Santo Spirito Hotels, Florence

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Check prices for these dates

Tonight
23 Feb - 24 Feb
Tomorrow
24 Feb - 25 Feb
This weekend
27 Feb - 1 Mar
Next weekend
6 Mar - 8 Mar

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Our top choices for Santo Spirito hotels

Panoramic Double Room, 1 Bedroom, Air conditioning, City View

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
Santo Spirito
10.0 out of 10, Exceptional, (25 reviews)
"My husband and I enjoyed our stay here! Large rooms and bathrooms, wonderful location, and great staff! "
United States
Christina
The price is NZ$298
includes taxes & fees
26 Feb - 27 Feb
SPIRIT OF FLORENCE Boutique Rooms
Royal Double Room

Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (107 reviews)
"It was a great stay. The renovation style is very tasteful. "
Singapore
Maoying
The price is NZ$358
includes taxes & fees
24 Feb - 25 Feb
Oltrarno Splendid
Double Room, Garden View

La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (173 reviews)
"The room was beautiful and clean, the staff was pleasant, breakfast was fantastic, 10/10"
United States
Dan
The price is NZ$223
includes taxes & fees
1 Mar - 2 Mar
La Fonderia Firenze
Lobby sitting area

AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (224 reviews)
"Wonderful room and everyone who worked at the hotel couldn’t be more helpful. Peaceful and calm, would thoroughly recommend."
United Kingdom
James
The price is NZ$352
includes taxes & fees
25 Feb - 26 Feb
AdAstra Suites
Rooftop terrace

Hotel Palazzo Guadagni

Hotel Palazzo Guadagni
3.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (201 reviews)
"Absolutely amazing stay! Great location to all major attractions, great restaurants nearby, beautiful rooms, certain room has Duomo view, incredibly helpful staff! Definitely recommend it and we are planning to come back! "
United States
Ann
The price is NZ$478
includes taxes & fees
8 Mar - 9 Mar
Hotel Palazzo Guadagni
Fireplace

Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (169 reviews)
"Great location and extremely charming!"
United States
Brook
The price is NZ$390
includes taxes & fees
19 Mar - 20 Mar
Ottantotto Firenze
Superior Double Room, 1 King Bed

La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.0 out of 10, Wonderful, (236 reviews)
"Great location and great rooms"
United States
David
La Torre Del Cestello
Lobby

Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (621 reviews)
"Wonderful place, super clean, very nice staff and wonderful breakfast. Also great location for beautiful walks not too close to areas overcrowded by tourists!"
United States
Gianmaria
The price is NZ$268
includes taxes & fees
1 Mar - 2 Mar
Hotel Horto Convento
Property entrance

Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
8.8 out of 10, Excellent, (140 reviews)
"Our stay was wonderful! Roxy was so welcoming and helpful! The room and view was beautiful as well! Great location with amazing food and sights nearby! "
United States
Jacqueline
Residenza D'Epoca Al Numero 8
Property entrance

Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (196 reviews)
"The room was clean a d comfortable, and the staff was very courteous and helpful. The location was also good with most attractions being a 30 to 40 minute walk or less."
United States
Roger
Foresteria Valdese di Firenze - Casa per Ferie
Suite

Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1,085 reviews)
"Clean room, great staff, excellent location."
United States
Joseph
Palazzo Mannaioni Suites
Front of property

Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca
Santo Spirito
9.4 out of 10, Exceptional, (46 reviews)
"Excellent place to stay!"
United States
Diane
The price is NZ$243
includes taxes & fees
9 Mar - 10 Mar
Palazzo D'Oltrarno - Residenza D'Epoca
Standard Double or Twin Room, 1 Double or 2 Single Beds, Private Bathroom

1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (178 reviews)
"Our stay here was wonderful! The host was so pleasant and the view from the terrace was beautiful. The location was in a great spot for enjoying the Florentine neighborhoods, and close to many of the restaurants recommended to us. We would stay here again in a heartbeat."
United States
Bianca
1900 Artevita
Bar (on property)

Hotel Firenze 2000

Hotel Firenze 2000
2.0 star property
Santo Spirito
7.2 out of 10, Good, (191 reviews)
"The staff was wonderful and very helpful; 24 hr service ! The room was very clean and breakfast was plentiful. Great location if you don’t mind a short walk to the historic town center ; would definitely recommend."
Canada
Josee
The price is NZ$177
includes taxes & fees
5 Mar - 6 Mar
Hotel Firenze 2000
Suite | Room amenity

Torre di Bellosguardo

Torre di Bellosguardo
4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103 reviews)
"Beautiful property and wonderful staff."
United States
Brad
The price is NZ$725
includes taxes & fees
24 Feb - 25 Feb
Torre di Bellosguardo
Interior

Casa Santo Nome di Gesù

Casa Santo Nome di Gesù
Santo Spirito
8.8 out of 10, Excellent, (344 reviews)
"Really a nice place, like the room style and good for family stay!"
United States
Ning
Casa Santo Nome di Gesù
Hallway

Soggiorno Alessandra

Soggiorno Alessandra
Santo Spirito
8.6 out of 10, Excellent, (86 reviews)
"Alessandra is an amazing host, we had a perfect stay! The apartment is in excellent condition and very clean! "
United States
Elias
Soggiorno Alessandra
Courtyard

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (137 reviews)
"Ver clean and quiet, wonderful stay."
United States
kevin
The price is NZ$146
includes taxes & fees
24 Feb - 25 Feb
Drom Florence Rooms & Apartments
Deluxe Apartment | Bathroom

Santo Spirito View by Mmega

Santo Spirito View by Mmega
Santo Spirito
8.6 out of 10, Excellent, (8 reviews)
"All as advertised and recommend"
United States
Jeff
Santo Spirito View by Mmega
Family Apartment | Living area

Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.6 out of 10, Excellent, (29 reviews)
"We stayed here in November and had a wonderful experience. The location worked perfectly for my husband and I, close enough to the center to get everywhere easily, yet set in a quiet residential part of Florence where we could feel the local rhythm of the city. The staff who look after the house were all very easy to communicate with. The whole stay was smooth and comfortable. We truly enjoyed our time here!"
United States
Ray
The price is NZ$326
includes taxes & fees
24 Feb - 25 Feb
Appartamenti degli Artisti by Mmega
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most.
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo featuring heritage architecture and a church or cathedral

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza di Santa Maria Novella or Via de' Calzaiuoli while you're exploring the neighbourhood.

Ponte Vecchio showing a bridge and a river or creek

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Basilica of Santa Croce showing a church or cathedral and religious elements

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

AdAstra Suites

AdAstra Suites

10/10 Excellent
"Gorgeous room in a beautiful property, very helpful staff, tranquil setting"
Olivia 1-night trip
Posted 4 days ago
AdAstra Suites

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighbourhood known for its stunning river views. Make sure that you visit Piazza Santo Spirito and Arno River as part of your Santo Spirito travel plans.
What's a favourite place to stay in Santo Spirito?
Based on Expedia customer reviews, Oltrarno Splendid is the highest ranked property in Santo Spirito. This B&B is a short 7-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and free WiFi. Other favourite options in the area include SPIRIT OF FLORENCE Boutique Rooms and La Fonderia Firenze.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 496 hotels and other accommodation options in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get top deals in Santo Spirito.
What can I see and do in this Florence neighbourhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighbourhood, Piazza Santo Spirito and Piazza del Carmine are some other places worth a visit. A few places to visit in the area around Santo Spirito include Piazza di Santa Maria Novella, Santa Maria della Carmine and Brancacci Chapel. When you're sightseeing in Florence, Il Nabucco di Matteo Gabellini and Teatro Comunale Florence are also worth a stop.

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