Santo Spirito Travel Guide
Tourist Guide





Visit Santo Spirito
Stay near popular Santo Spirito attractions
Activities

Reserved Entry Florence Duomo: Express Guided Tour

Florence: Pasta Cooking Class with Unlimited Wine

Accademia timed-entry Ticket with App Guide

Florence's Accademia Gallery Timed Entry Ticket

City Sightseeing Florence Hop-on Hop-off Bus Tour

Florence: Pizza & Gelato Masterclass Morning, Afternoon or Evening Delight
Our pick of the best Santo Spirito Hotel Deals

Hotel Horto Convento
"Absolutely amazing hotel. Beautiful grounds and building in a nice, quiet part of the neighborhood, but still so walkable and close to churches, museums, restaurants, etc. Cherish at check-in gave us some great recommendations for food nearby. Had some of the best baked goods I've ever had at breakfast ..."
Reviewed on 28 Sept 2026

La Torre Del Cestello
"The parking was difficult."
Reviewed on 28 Sept 2026

UNA Hotels Vittoria Firenze
"The entrance, the building, the lobby looked very well and promising. Room was small but ok. The shower was terrible, poor mainteined. Room decoration looked agressive. Breakfast was great. Location little far from downtown"
Reviewed on 6 Sept 2026

Casa Santo Nome di Gesù

Hostel Santa Monaca
"No"
Reviewed on 30 July 2026

Palazzo Mannaioni Suites
"Wonderful location and ideal living space, would have loved to stay there longer"
Reviewed on 30 Sept 2026
Our guide on where to stay in Santo Spirito

Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza del Duomo and Piazza di Santa Maria Novella are major draws. Catch the metro at UnitĆ Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza del Duomo or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Florence.

San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Croce
Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.























