Our guide on where to stay in Santo Spirito
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.
Our pick of the best Santo Spirito Hotel Deals
Reviewed on 23 May 2024
Reviewed on 23 May 2024
Reviewed on 23 Apr. 2024
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Discover the most popular places to visit in Santo Spirito
Piazza Santo Spirito
Learn about the local history of San Frediano with a stop at Piazza Santo Spirito. Discover the acclaimed art galleries and stunning cathedral in this vibrant area.
Porta Romana
Find out about the history of San Frediano when you spend time at Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.