Otay Mesa West Hotels, San Diego
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Otay Mesa West hotels
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG11 km from Otay Mesa West
8.2 out of 10, Very good, (1,696 reviews)
"Great breakfast!"
Susan
The price is NZ$228
includes taxes & fees
22 Apr - 23 Apr
Lafayette Hotel & Club
Lafayette Hotel & Club21.3 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,596 reviews)
"Everything about that stay was perfect"
Victoria
The price is NZ$486
includes taxes & fees
22 Apr - 23 Apr
Sheraton San Diego Resort
Sheraton San Diego Resort21.4 km from Otay Mesa West
8.4 out of 10, Very good, (3,466 reviews)
"Nice hotel with great location "
DIANA
The price is NZ$475
includes taxes & fees
3 May - 4 May
Best Western Americana Inn
Best Western Americana Inn2.1 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,256 reviews)
"Great place and service. Will definitely stay there again. "
Maria
The price is NZ$236
includes taxes & fees
26 Apr - 27 Apr
Sycuan Casino Resort
Sycuan Casino Resort31.2 km from Otay Mesa West
9.4 out of 10, Exceptional, (1,859 reviews)
"Awesome place "
Jonathan
The price is NZ$252
includes taxes & fees
19 Apr - 20 Apr
Bahia Resort Hotel
Bahia Resort HotelCentral Mission Beach, 28.2 km from Otay Mesa West
8.6 out of 10, Excellent, (1,993 reviews)
"We stay here a few times a year normally and love the location. "
Lindsay
The price is NZ$425
includes taxes & fees
10 May - 11 May
GreenTree Inn San Diego Mission Bay
GreenTree Inn San Diego Mission BayPacific Beach, 29.3 km from Otay Mesa West
8.0 out of 10, Very good, (2,029 reviews)
"Great stay"
Lizeth
The price is NZ$204
includes taxes & fees
26 Apr - 27 Apr
SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake12.4 km from Otay Mesa West
9.6 out of 10, Exceptional, (627 reviews)
"By far, one of the best hotels we have stayed at! Very clean, friendly and knowledgeable front desk staff, amenities galore and right across the street from family friendly entertainment venues like play city and ninja factory. The pool was amazing - we had all a great time! "
Daniel
The price is NZ$352
includes taxes & fees
3 May - 4 May
San Diego Mission Bay Resort
San Diego Mission Bay ResortMission Bay, 26.8 km from Otay Mesa West
8.4 out of 10, Very good, (1,414 reviews)
"The restaurant on site was delicious "
Blanca
The price is NZ$518
includes taxes & fees
26 Apr - 27 Apr
Embassy Suites by Hilton San Diego Bay Downtown
Embassy Suites by Hilton San Diego Bay Downtown18.4 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,727 reviews)
"Wonderful hotel and great location!! "
Jan
The price is NZ$475
includes taxes & fees
3 May - 4 May
Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG22.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,054 reviews)
"Clean room, friendly staff, and only a 15 minute walk to Old Town. Also conveniently located close to the airport just a short shuttle drive away. "
Olivia
The price is NZ$297
includes taxes & fees
26 Apr - 27 Apr
Marriott Marquis San Diego Marina
Marriott Marquis San Diego Marina17.9 km from Otay Mesa West
9.2 out of 10, Wonderful, (2,092 reviews)
"good atmosphere, good staff, friendly staff, good food, pool is amazing, restaurants are affordable and excellent."
Artsrun
The price is NZ$552
includes taxes & fees
2 May - 3 May
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Studio 6 Suites San Ysidro, CA -San Diego South Bay3.1 km from Otay Mesa West
8.0 out of 10, Very good, (1,604 reviews)
"Good location"
Joshua
The price is NZ$149
includes taxes & fees
19 Apr - 20 Apr
Old Town Inn
Old Town Inn23.7 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,850 reviews)
"Nice hotel, would stay here again. "
Samantha
The price is NZ$336
includes taxes & fees
22 Apr - 23 Apr
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel10.5 km from Otay Mesa West
9.2 out of 10, Wonderful, (3,782 reviews)
"Great hotel"
Deante
The price is NZ$285
includes taxes & fees
26 Apr - 27 Apr
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld24.7 km from Otay Mesa West
7.4 out of 10, Good, (4,197 reviews)
"great place"
souheil
The price is NZ$233
includes taxes & fees
26 Apr - 27 Apr
Ocean Beach Hotel
Ocean Beach HotelOcean Beach, 26.5 km from Otay Mesa West
8.8 out of 10, Excellent, (1,307 reviews)
"Cute place, easy location & staff was so friendly. "
Ericka A
The price is NZ$327
includes taxes & fees
20 Apr - 21 Apr
Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station22.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,702 reviews)
"Great location for the airport stay"
Christopher
The price is NZ$325
includes taxes & fees
26 Apr - 27 Apr
Courtyard by Marriott San Diego Airport/Liberty Station
Courtyard by Marriott San Diego Airport/Liberty Station22.8 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,298 reviews)
"Great hotel"
Amy
The price is NZ$346
includes taxes & fees
26 Apr - 27 Apr
Wyndham San Diego Bayside
Wyndham San Diego Bayside19.2 km from Otay Mesa West
8.4 out of 10, Very good, (6,122 reviews)
"Clean room and great location "
Evanthia
The price is NZ$412
includes taxes & fees
27 Apr - 28 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our guide on where to stay in Otay Mesa West
Find the best Otay Mesa West areas for the activities you enjoy most. Learn more about Otay Mesa West
Learn more about Otay Mesa West
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Gaslamp Quarter
The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.
Ocean Beach
Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Sunset Cliffs Natural Park.
Frequently asked questions
Explore a world of travel with Expedia
- Otay Hotels
- Hotels near Len Moore Skate Park
- Chula Vista Hotels
- Otay Mesa Hotels
- Hotels near San Diego-Coronado Bridge
- Hotels near Naval Base Coronado
- San Ysidro Hotels
- Hotels near Seaport Village
- San Diego Hotels
- Hotels near Maritime Museum of San Diego
- Nestor Hotels
- Hotels near Brown Field Municipal
- Gaslamp Quarter Hotels
- Spring Valley Hotels
- Encanto Hotels
- Logan Heights Hotels
- Imperial Beach Hotels
- San Diego County Hotels
- Hotels near Coronado Shopping Plaza Shopping Center
- Hotels near Palm Ave Trolley Station
- Bonita Hotels
- Eastlake Hotels
- Hotels near Sky Zone San Diego Indoor Trampoline Park
- Hotels near San Ysidro Border Crossing
- National City Hotels
- Hotels near B Street Cruise Ship Terminal
- Hotels near Chula Vista Elite Athlete Training Center
- Boutique Hotels in South Bay
- Cheap Hotels in Otay Mesa
- Romantic Hotels in South San Diego
- Beach Hotels in South San Diego
- Family Hotels in South San Diego
- Family Hotels in San Diego Coast
- All Inclusive Hotels in San Diego Coast
- Winery Hotels in San Diego Coast
- B&B in San Diego Coast
- Apartments in Chula Vista
- B&B in Chula Vista
- Residences in Chula Vista
- Hostels in San Ysidro
- Guest Houses in South Bay
- Holiday Homes in South Bay
- Serviced Apartments in South Bay
- Villas in South Bay
- Apartments in South Bay
- Cottages in South Bay
- Holiday Homes in Imperial Beach
- Apartments in Imperial Beach
- Best Western Hotels in San Ysidro
- Flights to San Ysidro
- Flights to National City
- Flights to Chula Vista
- Flights from Henderson (HSH) to San Diego (SDM)
- Flights from Long Beach (LGB) to San Diego (SDM)
- Flights from Los Angeles (LAX) to San Diego (SDM)
- Flights from Sydney (SYD) to San Diego (SDM)
- Flights from Hartford (BDL) to San Diego (SDM)
- Flights from San Francisco (SFO) to San Diego (SDM)
- Flights from Houston (IAH) to San Diego (SDM)
- Flights from Boston (BOS) to San Diego (SDM)
- Flights from Orange County (SNA) to San Diego (SDM)
- Flights from Hong Kong (HKG) to San Diego (SDM)
- Flights from Denver (DEN) to San Diego (SDM)
- Flights from Las Vegas (LAS) to San Diego (SDM)
- Flights from Brown Field Municipal
- San Ysidro Border Crossing
- Silver Strand State Beach
- Sharp Chula Vista Medical Center
- Chula Vista Center
- Chula Vista Elite Athlete Training Center
- North Island Credit Union Amphitheatre
- Kaiser Permanente Otay Mesa Medical Offices
- Atlantis Laser Tag
- Las Americas Premium Outlets
- Visit Otay Mesa
- Visit Chula Vista
- Visit Eastlake Greens
- Visit Otay Mesa West
- Visit Bonita
- Visit National City
- Visit Rancho del Rey
- Visit Otay
- Visit Bay Terraces
- All inclusive Holiday Packages San Diego Coast