Otay Mesa Hotels, San Diego

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Check prices for these dates

Tonight
13 Feb - 14 Feb
Tomorrow
14 Feb - 15 Feb
This weekend
13 Feb - 15 Feb
Next weekend
20 Feb - 22 Feb

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Our top choices for Otay Mesa hotels

Free buffet breakfast

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very good, (1,643 reviews)
"Clean, great breakfast, good service."
United States
Sara
The price is NZ$243
includes taxes & fees
8 Mar - 9 Mar
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Free on-the-go breakfast

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.0 out of 10, Good, (1,001 reviews)
"Great staff.. location close to the airport!"
United States
Vivian
The price is NZ$187
includes taxes & fees
15 Feb - 16 Feb
Quality Suites San Diego Otay Mesa
Exterior

The Sofia Hotel

The Sofia Hotel
3.5 star property
24.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,762 reviews)
"Great hotel "
United States
Alexander
The Sofia Hotel
5 outdoor pools, a heated pool, pool umbrellas, pool loungers

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay, 34.5 km from Otay Mesa
8.6 out of 10, Excellent, (2,412 reviews)
"Clean Rooms, staff very friendly, very relaxing place "
United States
AlmaDelia
The price is NZ$385
includes taxes & fees
1 Mar - 2 Mar
Paradise Point Resort & Spa
Lobby lounge

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
24.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,486 reviews)
"Great location. Good value for money."
United States
Mohammad
The Bristol Hotel San Diego
Interior entrance

Westgate Hotel

Westgate Hotel
4.5 star property
24.9 km from Otay Mesa
9.0 out of 10, Wonderful, (1,001 reviews)
"Great stay"
United States
ESMERALDA
Westgate Hotel
3 restaurants, breakfast, lunch, dinner served; Regional cuisine

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
25.7 km from Otay Mesa
8.4 out of 10, Very good, (6,026 reviews)
"Great place to stay"
United States
David
The price is NZ$350
includes taxes & fees
16 Feb - 17 Feb
Wyndham San Diego Bayside
Exterior

Holiday Inn Express San Diego Downtown by IHG

Holiday Inn Express San Diego Downtown by IHG
2.5 star property
24.9 km from Otay Mesa
8.4 out of 10, Very good, (1,599 reviews)
"Lovely stay, friendly staff and great breakfast "
Canada
Louella
The price is NZ$260
includes taxes & fees
1 Mar - 2 Mar
Holiday Inn Express San Diego Downtown by IHG
Standard Room, 1 King Bed, Non Smoking, Bay View

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
25.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1,048 reviews)
"Great restaurant/Bar."
United States
Maria Elena
The price is NZ$223
includes taxes & fees
22 Feb - 23 Feb
The DEXTRO Little Italy, BW Premier Collection
Lobby

Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
25 km from Otay Mesa
9.0 out of 10, Wonderful, (1,628 reviews)
"Very easy vacation, convenient breakfast as well as location."
United States
Kathy
The price is NZ$390
includes taxes & fees
1 Mar - 2 Mar
Embassy Suites by Hilton San Diego Bay Downtown
Lobby sitting area

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
31.3 km from Otay Mesa
7.4 out of 10, Good, (4,149 reviews)
"Good location friendly staff"
United States
Anya
The price is NZ$161
includes taxes & fees
19 Feb - 20 Feb
Wyndham Garden San Diego Near SeaWorld
3 outdoor pools, pool cabanas (surcharge), pool umbrellas

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay, 33.9 km from Otay Mesa
8.4 out of 10, Very good, (1,598 reviews)
"Balcony view is awesome, clean room, staff at counter and restaurant service was stunning."
United States
francisco
The price is NZ$391
includes taxes & fees
26 Feb - 27 Feb
Hyatt Regency Mission Bay Spa and Marina
Front of property – evening/night

Handlery Hotel

Handlery Hotel
3.5 star property
29.1 km from Otay Mesa
8.2 out of 10, Very good, (2,308 reviews)
"Staff was amazing, rooms were clean, and very quiet!"
United States
Michelle
The price is NZ$193
includes taxes & fees
22 Feb - 23 Feb
Handlery Hotel
2 outdoor pools, a heated pool, pool loungers

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay, 33.8 km from Otay Mesa
9.0 out of 10, Wonderful, (4,079 reviews)
"Great location and grounds!"
United States
Ethan
The price is NZ$360
includes taxes & fees
23 Feb - 24 Feb
The Dana on Mission Bay
Breakfast, lunch, dinner served; Mediterranean cuisine

Bahia Resort Hotel

Bahia Resort Hotel
3.5 star property
Central Mission Beach, 34.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,878 reviews)
"Amazing place "
United States
Richard
The price is NZ$382
includes taxes & fees
1 Mar - 2 Mar
Bahia Resort Hotel
Lobby sitting area

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
29.1 km from Otay Mesa
8.8 out of 10, Excellent, (3,625 reviews)
"Love the Kings Inn, always on our travel list!!"
United States
Linzee
Kings Inn San Diego
Restaurant

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 24.1 km from Otay Mesa
9.0 out of 10, Wonderful, (1,269 reviews)
"Clean room, friendly staff, great location Very affordable rate Good breakfast variety "
United States
Mary
The price is NZ$249
includes taxes & fees
16 Feb - 17 Feb
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3 outdoor pools, pool cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.5 km from Otay Mesa
9.2 out of 10, Wonderful, (1,731 reviews)
"Very clean resort. "
United States
Petrina
Sycuan Casino Resort
Standard Room, 2 Queen Beds, Non Smoking, Microwave

Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel
2.5 star property
29.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,727 reviews)
"Well stay again love the location"
United States
Lynette
The price is NZ$207
includes taxes & fees
3 Mar - 4 Mar
Best Western Yacht Harbor Hotel
Lobby sitting area

Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter
4.0 star property
Gaslamp Quarter, 24.5 km from Otay Mesa
8.8 out of 10, Excellent, (2,240 reviews)
"The rooms were clean, the staff was very friendly. I would stay there again"
United States
Kadisha
The price is NZ$257
includes taxes & fees
16 Feb - 17 Feb
Palihotel San Diego Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa
Seaport Village featuring a church or cathedral

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Seaport Village and Petco Park are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Belmont Park which includes rides

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Pacific Beach Park showing surfing, swimming and rugged coastline

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Gaslamp Quarter featuring signage

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Ocean Beach

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach and Dog Beach.

Top Otay Mesa Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"Nice hotel i would stay here again."
Modesto 2-night trip
Posted 6 hours ago
The DEXTRO Little Italy, BW Premier Collection

Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on Expedia customer reviews, Quality Suites San Diego Otay Mesa is the highest ranked property in Otay Mesa. This hotel offers free breakfast and free parking.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! Most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.
What is there to do in this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

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