Otay Mesa Hotels, San Diego

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25 Sept - 26 Sept
Tomorrow
26 Sept - 27 Sept
This weekend
26 Sept - 28 Sept
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3 Oct - 5 Oct

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4771 Cheap Hotels in Otay Mesa - Specials, Reviews, & Last Minute Deals

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Exterior

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
8.0 out of 10, Very good, (1475)
"Very good to stayed "
The price is NZ$221
includes taxes & fees
1 Oct - 2 Oct
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Quality Suites San Diego Otay Mesa
Desk, laptop workspace, blackout curtains, iron/ironing board

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1007)
"Hotel was great the staff was very attentive. "
The price is NZ$211
includes taxes & fees
5 Oct - 6 Oct
Quality Suites San Diego Otay Mesa
Ayres Hotel San Diego South - Chula Vista
Lobby lounge

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1097)
"Very nice clean hotel "
The price is NZ$256
includes taxes & fees
8 Oct - 9 Oct
Ayres Hotel San Diego South - Chula Vista
SpringHill Suites by Marriott Chula Vista Eastlake
Outdoor pool

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (455)
"Nice hotel, nice pool, free breakfast, clean spacious rooms. "
The price is NZ$260
includes taxes & fees
5 Oct - 6 Oct
SpringHill Suites by Marriott Chula Vista Eastlake
Sycuan Casino Resort
3 outdoor pools, pool cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1549)
"Great resort!"
Sycuan Casino Resort
Legacy Resort Hotel & Spa
Garden

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2891)
"Great stay overall"
The price is NZ$310
includes taxes & fees
28 Sept - 29 Sept
Legacy Resort Hotel & Spa
Staypineapple, Hotel Z, Gaslamp San Diego
Premium bedding, pillow-top beds, desk, blackout curtains

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
9.4 out of 10, Exceptional, (1000)
"Very cute and comfortable stay"
The price is NZ$329
includes taxes & fees
12 Oct - 13 Oct
Staypineapple, Hotel Z, Gaslamp San Diego
Best Western Plus Marina Gateway Hotel
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed)

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3322)
"Good place to stay"
The price is NZ$263
includes taxes & fees
28 Sept - 29 Sept
Best Western Plus Marina Gateway Hotel
Humphreys Half Moon Inn
Outdoor pool

Humphreys Half Moon Inn

3.5 star property
9.2 out of 10, Wonderful, (2547)
"Great front desk staff and beautiful grounds"
The price is NZ$327
includes taxes & fees
26 Oct - 27 Oct
Humphreys Half Moon Inn
Lafayette Hotel & Club
Outdoor pool, open 7:00 AM to 9:00 PM, pool cabanas (surcharge)

Lafayette Hotel & Club

4.0 star property
9.2 out of 10, Wonderful, (1166)
"Amazing, celebrated my birthday here with girlfriends and it was everything and more!"
The price is NZ$446
includes taxes & fees
29 Sept - 30 Sept
Lafayette Hotel & Club
Omni San Diego Hotel at the Ballpark
Lobby sitting area

Omni San Diego Hotel at the Ballpark

4.0 star property
9.2 out of 10, Wonderful, (2036)
"Love this hotel, wonderful staff and location "
The price is NZ$558
includes taxes & fees
2 Oct - 3 Oct
Omni San Diego Hotel at the Ballpark
Gaslamp Plaza Suites
Lobby

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1024)
"Great stay and great for tourist "
The price is NZ$203
includes taxes & fees
30 Sept - 1 Oct
Gaslamp Plaza Suites
Sentral Gaslamp Quarter
Premium bedding, pillow-top beds, desk, laptop workspace

Sentral Gaslamp Quarter

3.0 star property
9.2 out of 10, Wonderful, (412)
"Great place to stay!"
The price is NZ$317
includes taxes & fees
28 Sept - 29 Sept
Sentral Gaslamp Quarter
Westgate Hotel
Outdoor pool, pool loungers

Westgate Hotel

4.5 star property
9.0 out of 10, Wonderful, (1018)
"Really enjoyed our stay at the property. We have stayed here before and loved the location, room size, and rooftop pool/gym. "
Westgate Hotel
The Rambler
View from room

The Rambler

3.0 star property
9.0 out of 10, Wonderful, (1950)
"Nice motel with a very cool café and Arcade inside. The coffee is super bomb ! "
The price is NZ$197
includes taxes & fees
29 Sept - 30 Sept
The Rambler
The Horton Grand, Downtown/Gaslamp Quarter
Serves dinner and happy hour

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2562)
"great stay, very clean!"
The Horton Grand, Downtown/Gaslamp Quarter
Alma San Diego Downtown, a Tribute Portfolio Hotel
Presidential Suite, 2 Bedrooms, Non Smoking | Living room

Alma San Diego Downtown, a Tribute Portfolio Hotel

4.0 star property
9.0 out of 10, Wonderful, (812)
"Great stay!"
The price is NZ$400
includes taxes & fees
5 Oct - 6 Oct
Alma San Diego Downtown, a Tribute Portfolio Hotel
Hotel Republic San Diego, Autograph Collection
Lobby

Hotel Republic San Diego, Autograph Collection

4.0 star property
9.0 out of 10, Wonderful, (1129)
"Nice place to stay"
The price is NZ$404
includes taxes & fees
2 Oct - 3 Oct
Hotel Republic San Diego, Autograph Collection
Bay Club Hotel & Marina
Exterior

Bay Club Hotel & Marina

3.5 star property
9.0 out of 10, Wonderful, (2971)
"We really enjoyed our stay"
The price is NZ$288
includes taxes & fees
28 Sept - 29 Sept
Bay Club Hotel & Marina
Margaritaville Hotel San Diego Gaslamp Quarter
Exterior

Margaritaville Hotel San Diego Gaslamp Quarter

4.0 star property
9.0 out of 10, Wonderful, (1049)
"Hotel was great"
The price is NZ$481
includes taxes & fees
29 Sept - 30 Sept
Margaritaville Hotel San Diego Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring a bar, street scenes and a city

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach Park featuring a beach

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Belmont Park which includes a garden and rides

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Otay Mesa Hotel Reviews

Bay Club Hotel & Marina

Bay Club Hotel & Marina

10/10 Excellent
"Beautiful "
Tanya 2-night trip
Posted 6 days ago
Bay Club Hotel & Marina

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! Most room reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.

What is there to do in this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.