Otay Mesa Hotels, San Diego

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Check prices for these dates

Tonight
4 Aug - 5 Aug
Tomorrow
5 Aug - 6 Aug
This weekend
8 Aug - 10 Aug
Next weekend
15 Aug - 17 Aug

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4633 Cheap Hotels in Otay Mesa - Specials, Reviews, & Last Minute Deals

Sycuan Casino Resort
3 outdoor pools, pool cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1457)
"We had a wonderful stay, will definitely visit again!"
Sycuan Casino Resort
Best Western San Diego Pacific Beach/Mission Bay
Outdoor pool

Best Western San Diego Pacific Beach/Mission Bay

2.5 star property
7.2 out of 10, Good, (1258)
"Excellent hotel !! "
The price is NZ$182
includes taxes & fees
7 Aug - 8 Aug
Best Western San Diego Pacific Beach/Mission Bay
Hampton Inn & Suites San Diego Seaworld
Reception

Hampton Inn & Suites San Diego Seaworld

2.5 star property
6.0 out of 10, (6)
"Nice new hotel, comfortable bed, clean, quiet and friendly staff"
The price is NZ$278
includes taxes & fees
6 Aug - 7 Aug
Hampton Inn & Suites San Diego Seaworld
Quality Suites San Diego Otay Mesa
Desk, laptop workspace, blackout curtains, iron/ironing board

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1005)
"Great location and spacious room "
The price is NZ$210
includes taxes & fees
9 Aug - 10 Aug
Quality Suites San Diego Otay Mesa
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Exterior

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
7.8 out of 10, Good, (1413)
"Great stay, close to the Cross Border Xpress "
The price is NZ$227
includes taxes & fees
10 Aug - 11 Aug
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Sea Harbor Hotel
Marina

Sea Harbor Hotel

2.0 star property
8.6 out of 10, Excellent, (912)
"Great location, very customer friendly staff."
The price is NZ$270
includes taxes & fees
5 Aug - 6 Aug
Sea Harbor Hotel
Best Western Plus Marina Gateway Hotel
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed)

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3181)
"This location was great for our family get away"
The price is NZ$267
includes taxes & fees
1 Sept - 2 Sept
Best Western Plus Marina Gateway Hotel
Berkshire Motor Hotel
Suite | Private kitchenette

Berkshire Motor Hotel

2.5 star property
8.4 out of 10, Very good, (953)
"Great location within walking distance from the places we wanted to visit."
The price is NZ$180
includes taxes & fees
10 Aug - 11 Aug
Berkshire Motor Hotel
Best Western Americana Inn
1 bedroom, pillow-top beds, in-room safe, desk

Best Western Americana Inn

2.5 star property
9.0 out of 10, Wonderful, (1119)
"The breakfast was very good and the front desk and housekeeping hospitality were great. I would definitely stay here again!"
The price is NZ$235
includes taxes & fees
11 Aug - 12 Aug
Best Western Americana Inn
SpringHill Suites by Marriott Chula Vista Eastlake
Outdoor pool

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (391)
"Clean property and great breakfast!"
The price is NZ$270
includes taxes & fees
10 Aug - 11 Aug
SpringHill Suites by Marriott Chula Vista Eastlake
La Quinta Inn by Wyndham San Diego Chula Vista
Exterior

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1336)
"Love the breakfast and convenient location. "
The price is NZ$209
includes taxes & fees
1 Sept - 2 Sept
La Quinta Inn by Wyndham San Diego Chula Vista
Ayres Hotel San Diego South - Chula Vista
Lobby lounge

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1087)
"Prefect stay with the family. Would stay again and recommend to friends. "
The price is NZ$446
includes taxes & fees
7 Aug - 8 Aug
Ayres Hotel San Diego South - Chula Vista
Loews Coronado Bay Resort
Exterior

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1014)
"Loved our stay very accommodating "
The price is NZ$450
includes taxes & fees
1 Sept - 2 Sept
Loews Coronado Bay Resort
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Desk, blackout curtains, iron/ironing board, free WiFi

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.8 out of 10, Good, (1175)
"Nice hotel to stay in "
The price is NZ$160
includes taxes & fees
11 Aug - 12 Aug
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Valli Hi Motel
Desk, blackout curtains, soundproofing, free WiFi

Valli Hi Motel

2.5 star property
8.2 out of 10, Very good, (1017)
"Great hotel "
Valli Hi Motel
Quality Inn San Diego South - Chula Vista
Coffee service

Quality Inn San Diego South - Chula Vista

2.5 star property
7.8 out of 10, Good, (1006)
"Staff and front desk were very friendly and helpful."
The price is NZ$172
includes taxes & fees
10 Aug - 11 Aug
Quality Inn San Diego South - Chula Vista
Sentral Gaslamp Quarter
Premium bedding, pillow-top beds, desk, laptop workspace

Sentral Gaslamp Quarter

3.0 star property
9.2 out of 10, Wonderful, (237)
"great place to stay"
The price is NZ$340
includes taxes & fees
17 Aug - 18 Aug
Sentral Gaslamp Quarter
The Rambler Motel
View from room

The Rambler Motel

3.0 star property
9.0 out of 10, Wonderful, (1882)
"Very pleased with this stay."
The price is NZ$213
includes taxes & fees
5 Aug - 6 Aug
The Rambler Motel
Howard Johnson by Wyndham National City/San Diego South
Hair dryer, towels

Howard Johnson by Wyndham National City/San Diego South

2.0 star property
7.2 out of 10, Good, (1005)
"Great place 👍"
The price is NZ$141
includes taxes & fees
10 Aug - 11 Aug
Howard Johnson by Wyndham National City/San Diego South
Best Western Chula Vista/Otay Valley Hotel
Lobby

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1462)
"Clean, great staff. "
The price is NZ$220
includes taxes & fees
24 Aug - 25 Aug
Best Western Chula Vista/Otay Valley Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Belmont Park which includes a garden and rides
Mission Beach map

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach Park featuring a beach
Pacific Beach map

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Gaslamp Quarter featuring a bar, street scenes and a city
Gaslamp Quarter map

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Ocean Beach map

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Otay Mesa Hotel Reviews

San Diego Mission Bay Resort

San Diego Mission Bay Resort

10/10 Excellent
"The staff was friendly and very helpful. They went out of their way to make you feel at home."
Arthur 3-night trip
Posted 18 hours ago
San Diego Mission Bay Resort

Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.

How many hotels will I find in the Otay Mesa area?

Expedia has 5 Otay Mesa hotels and other accommodation options, and one might make a good home base for venturing out into the greater San Diego area.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! Most room reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.

What is there to do in this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.