Otay Mesa Hotels, San Diego

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4826 Cheap Hotels in Otay Mesa - Specials, Reviews, & Last Minute Deals

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
Otay Mesa
8.0 out of 10, Very good, (1531)
"Good comfortable beds good breakfast "
United States
Andrey
The price is NZ$260
includes taxes & fees
16 Nov - 17 Nov
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Quality Suites San Diego Otay Mesa

2.5 star property
Otay Mesa
7.0 out of 10, Good, (1000)
"Hotel was great the staff was very attentive. "
United States
Anibal
The price is NZ$193
includes taxes & fees
16 Nov - 17 Nov
Quality Suites San Diego Otay Mesa

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
Gaslamp Quarter, 24.1 km from Otay Mesa
9.0 out of 10, Wonderful, (1208)
"Clean room ,friendly staff, great location "
United States
Jessica
The price is NZ$243
includes taxes & fees
23 Nov - 24 Nov
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
24.3 km from Otay Mesa
9.0 out of 10, Wonderful, (2651)
"Very nice location and rooms. "
United States
David
The Horton Grand, Downtown/Gaslamp Quarter

Hard Rock Hotel San Diego

4.0 star property
Gaslamp Quarter, 24 km from Otay Mesa
9.0 out of 10, Wonderful, (3076)
"Our stay was great! Would stay here again"
United States
Carla
The price is NZ$409
includes taxes & fees
8 Dec - 9 Dec
Hard Rock Hotel San Diego

Palihotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 24.5 km from Otay Mesa
8.6 out of 10, Excellent, (2028)
"Clean room, excellent staff and pleasant atmosphere "
United States
Estela
The price is NZ$236
includes taxes & fees
23 Nov - 24 Nov
Palihotel San Diego Gaslamp Quarter

AC Hotel by Marriott San Diego Downtown Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 24.4 km from Otay Mesa
8.8 out of 10, Excellent, (949)
"Great spot in Gaslamp! "
United States
Cassie
The price is NZ$246
includes taxes & fees
27 Nov - 28 Nov
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter

Wyndham San Diego Bayside

4.0 star property
25.7 km from Otay Mesa
8.4 out of 10, Very good, (6035)
"I enjoyed my stay."
United States
Kevin
The price is NZ$329
includes taxes & fees
23 Nov - 24 Nov
Wyndham San Diego Bayside

El Cordova Hotel on Coronado Island

3.5 star property
23.5 km from Otay Mesa
8.8 out of 10, Excellent, (1004)
"Thank you - great spot! I will stay again ⭐️ "
United States
Donna
The price is NZ$324
includes taxes & fees
8 Dec - 9 Dec
El Cordova Hotel on Coronado Island

Best Western Plus Marina Gateway Hotel

3.5 star property
16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3392)
"Clean, staff friendly, great place for a stay"
United States
Derrick
The price is NZ$225
includes taxes & fees
30 Nov - 1 Dec
Best Western Plus Marina Gateway Hotel

Gaslamp Plaza Suites

3.5 star property
Gaslamp Quarter, 24.6 km from Otay Mesa
8.8 out of 10, Excellent, (1005)
"An extremely clean and well kept vintage property. I loved the traditional hotel qualities, mended with modern amenities. A repeat stay is probable. "
United States
Paul
The price is NZ$222
includes taxes & fees
9 Dec - 10 Dec
Gaslamp Plaza Suites

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
Gaslamp Quarter, 24.2 km from Otay Mesa
9.4 out of 10, Exceptional, (1003)
"The room was immaculate, the staff were helpful and friendly and our stay was so wonderful. "
United States
Samantha Erin
The price is NZ$266
includes taxes & fees
27 Nov - 28 Nov
Staypineapple, Hotel Z, Gaslamp San Diego

Best Western Plus Suites Hotel Coronado Island

2.5 star property
24.1 km from Otay Mesa
8.8 out of 10, Excellent, (1002)
"Great staff and breakfast "
United States
Samantha
The price is NZ$296
includes taxes & fees
30 Nov - 1 Dec
Best Western Plus Suites Hotel Coronado Island

The Sofia Hotel

3.5 star property
24.9 km from Otay Mesa
8.4 out of 10, Very good, (1626)
"Excellent stay all-around!"
United States
Nalani
The Sofia Hotel

The Bristol Hotel San Diego

3.5 star property
24.9 km from Otay Mesa
8.6 out of 10, Excellent, (1427)
"Nice staff, comfortable beds"
United States
Amber
The Bristol Hotel San Diego

Holiday Inn Express San Diego Downtown by IHG

2.5 star property
24.9 km from Otay Mesa
8.4 out of 10, Very good, (1527)
"Very nice hotel. "
United States
James
The price is NZ$210
includes taxes & fees
15 Dec - 16 Dec
Holiday Inn Express San Diego Downtown by IHG

Courtyard by Marriott San Diego Downtown

4.0 star property
24.6 km from Otay Mesa
8.8 out of 10, Excellent, (1002)
"It was a good stay, the room seemed clean and "
United States
Soraya Lizbeth
The price is NZ$269
includes taxes & fees
15 Dec - 16 Dec
Courtyard by Marriott San Diego Downtown

Best Western Plus La Mesa San Diego

2.5 star property
24.5 km from Otay Mesa
8.2 out of 10, Very good, (1003)
"Great place "
United States
Fadi
The price is NZ$184
includes taxes & fees
11 Dec - 12 Dec
Best Western Plus La Mesa San Diego

Alma San Diego Downtown, a Tribute Portfolio Hotel

4.0 star property
24.7 km from Otay Mesa
9.0 out of 10, Wonderful, (844)
"Lovely hotel. Really enjoyed the complimentary bottle of wine as well as how convenient it was to walk to restaurants & bars . "
United States
Gisselle
The price is NZ$331
includes taxes & fees
15 Dec - 16 Dec
Alma San Diego Downtown, a Tribute Portfolio Hotel

Margaritaville Hotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 24.1 km from Otay Mesa
9.0 out of 10, Wonderful, (1128)
"Great Hotel - good position and very helpful staff. "
United Kingdom
James
The price is NZ$395
includes taxes & fees
23 Nov - 24 Nov
Margaritaville Hotel San Diego Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Otay Mesa with free breakfast

Hotels in Otay Mesa with a pool

Top guest rated hotels in Otay Mesa

Our guide on where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Otay Mesa Hotel Reviews

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Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! Most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.
What is there to do in this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.