Otay Mesa Hotels, San Diego

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4845 Cheap Hotels in Otay Mesa - Specials, Reviews, & Last Minute Deals

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
Otay Mesa
8.0 out of 10, Very good, (1520)
"Good comfortable beds good breakfast "
United States
Andrey
The price is NZ$260
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Quality Suites San Diego Otay Mesa

2.5 star property
Otay Mesa
7.2 out of 10, Good, (1002)
"Hotel was great the staff was very attentive. "
United States
Anibal
The price is NZ$200
includes taxes & fees
12 Nov - 13 Nov
Quality Suites San Diego Otay Mesa

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
Gaslamp Quarter, 24.1 km from Otay Mesa
9.0 out of 10, Wonderful, (1205)
"Clean room ,friendly staff, great location "
United States
Jessica
The price is NZ$260
includes taxes & fees
23 Nov - 24 Nov
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
24.3 km from Otay Mesa
9.0 out of 10, Wonderful, (2652)
"Very nice location and rooms. "
United States
David
The Horton Grand, Downtown/Gaslamp Quarter

Hard Rock Hotel San Diego

4.0 star property
Gaslamp Quarter, 24 km from Otay Mesa
9.0 out of 10, Wonderful, (3070)
"Our stay was great! Would stay here again"
United States
Carla
The price is NZ$346
includes taxes & fees
23 Nov - 24 Nov
Hard Rock Hotel San Diego

Palihotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 24.5 km from Otay Mesa
8.6 out of 10, Excellent, (2015)
"Clean room, excellent staff and pleasant atmosphere "
United States
Estela
The price is NZ$236
includes taxes & fees
23 Nov - 24 Nov
Palihotel San Diego Gaslamp Quarter

AC Hotel by Marriott San Diego Downtown Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 24.4 km from Otay Mesa
8.8 out of 10, Excellent, (948)
"Great spot in Gaslamp! "
United States
Cassie
The price is NZ$257
includes taxes & fees
23 Nov - 24 Nov
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter

Wyndham San Diego Bayside

4.0 star property
25.7 km from Otay Mesa
8.4 out of 10, Very good, (6041)
"So Close to Cruise Port! Staff were Excellent!!"
Canada
Donna
The price is NZ$329
includes taxes & fees
23 Nov - 24 Nov
Wyndham San Diego Bayside

El Cordova Hotel on Coronado Island

3.5 star property
23.5 km from Otay Mesa
8.8 out of 10, Excellent, (1008)
"Thank you - great spot! I will stay again ⭐️ "
United States
Donna
The price is NZ$326
includes taxes & fees
30 Nov - 1 Dec
El Cordova Hotel on Coronado Island

Gaslamp Plaza Suites

3.5 star property
Gaslamp Quarter, 24.6 km from Otay Mesa
9.0 out of 10, Wonderful, (1007)
"Everything was amazing! Both of the hotel desk clerks at check-in in the afternoon were so helpful, kind, and knowledgeable. Plenty of places to walk to and eat around the hotel. Clean and felt safe!"
United States
Yadira
The price is NZ$225
includes taxes & fees
9 Dec - 10 Dec
Gaslamp Plaza Suites

Best Western Plus Marina Gateway Hotel

3.5 star property
16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3388)
"Clean, staff friendly, great place for a stay"
United States
Derrick
The price is NZ$244
includes taxes & fees
23 Nov - 24 Nov
Best Western Plus Marina Gateway Hotel

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
Gaslamp Quarter, 24.2 km from Otay Mesa
9.4 out of 10, Exceptional, (1011)
"They let me check in early and check out late. the staff was great. Ill def be trying to book there again for the conference i was at next year. "
United States
Justin
The price is NZ$266
includes taxes & fees
24 Nov - 25 Nov
Staypineapple, Hotel Z, Gaslamp San Diego

Best Western Plus Suites Hotel Coronado Island

2.5 star property
24.1 km from Otay Mesa
8.8 out of 10, Excellent, (1005)
"Great staff and breakfast "
United States
Samantha
The price is NZ$299
includes taxes & fees
30 Nov - 1 Dec
Best Western Plus Suites Hotel Coronado Island

The Sofia Hotel

3.5 star property
24.9 km from Otay Mesa
8.4 out of 10, Very good, (1627)
"Great location, great rooms. Friendly & helpful staff, I will definitely look to go there again."
United Kingdom
RICHARD
The price is NZ$325
includes taxes & fees
20 Nov - 21 Nov
The Sofia Hotel

Courtyard by Marriott San Diego Downtown

4.0 star property
24.6 km from Otay Mesa
8.8 out of 10, Excellent, (1016)
"It was a good stay, the room seemed clean and "
United States
Soraya Lizbeth
The price is NZ$271
includes taxes & fees
23 Nov - 24 Nov
Courtyard by Marriott San Diego Downtown

The Bristol Hotel San Diego

3.5 star property
24.9 km from Otay Mesa
8.6 out of 10, Excellent, (1423)
"Nice staff, comfortable beds"
United States
Amber
The Bristol Hotel San Diego

Holiday Inn Express San Diego Downtown by IHG

2.5 star property
24.9 km from Otay Mesa
8.4 out of 10, Very good, (1524)
"Clean corner room, great breakfast, safe and affordable "
United States
Janeen
The price is NZ$226
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Express San Diego Downtown by IHG

Best Western Plus La Mesa San Diego

2.5 star property
24.5 km from Otay Mesa
8.2 out of 10, Very good, (1005)
"Great place "
United States
Fadi
The price is NZ$186
includes taxes & fees
11 Dec - 12 Dec
Best Western Plus La Mesa San Diego

Marriott Marquis San Diego Marina

4.0 star property
24.5 km from Otay Mesa
9.2 out of 10, Wonderful, (1906)
"Great property and friendly people"
United States
Cynthia
The price is NZ$420
includes taxes & fees
23 Nov - 24 Nov
Marriott Marquis San Diego Marina

Margaritaville Hotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 24.1 km from Otay Mesa
9.0 out of 10, Wonderful, (1122)
"Great Hotel - good position and very helpful staff. "
United Kingdom
James
The price is NZ$402
includes taxes & fees
24 Nov - 25 Nov
Margaritaville Hotel San Diego Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Otay Mesa with free breakfast

Hotels in Otay Mesa with a pool

Top guest rated hotels in Otay Mesa

Our guide on where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Otay Mesa Hotel Reviews

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Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! Most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.
What is there to do in this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.