Spa Hotels & Resorts in James Island from NZ$284
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on James Island Spa Hotels
Our top choices for James Island hotels with a spa
Harborside at Charleston Harbor Resort and Marina
Harborside at Charleston Harbor Resort and MarinaMount Pleasant
8.6 out of 10, Excellent, (2,036 reviews)
"Everything was great! "
GLOVENIA
9.0 out of 10, Wonderful, (2,058 reviews)
"great location, Beautiful older hotel, staff very friendly and helpful"
elizabeth
The price is NZ$284
includes taxes & fees
18 Jan - 19 Jan
The Beach Club at Charleston Harbor Resort and Marina
The Beach Club at Charleston Harbor Resort and MarinaMount Pleasant
9.2 out of 10, Wonderful, (1,000 reviews)
"The resort is absolutely beautiful. My week stay was amazing and relaxing."
Melissa
The price is NZ$320
includes taxes & fees
19 Jan - 20 Jan
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
Wild Dunes Resort – Sweetgrass Inn and Boardwalk InnIsle of Palms
8.8 out of 10, Excellent, (1,003 reviews)
"We loved this resort! It was comfortable, convenient, and had a touch of everything for everyone. A great stay. "
Meghan
The price is NZ$487
includes taxes & fees
26 Jan - 27 Jan
Wild Dunes Resort – Residences at Sweetgrass
Wild Dunes Resort – Residences at SweetgrassIsle of Palms
8.6 out of 10, Excellent, (179 reviews)
"Love it "
Lawanda
The price is NZ$536
includes taxes & fees
18 Jan - 19 Jan
9.6 out of 10, Exceptional, (1,001 reviews)
"Very nice , helpful and friendly staff, great location. Great ambiance for family vacation. "
Nazanin
9.6 out of 10, Exceptional, (1,002 reviews)
"Wonderful stay!"
Suzanne
The price is NZ$483
includes taxes & fees
22 Jan - 23 Jan
9.6 out of 10, Exceptional, (983 reviews)
"Great stay "
Christopher
The price is NZ$737
includes taxes & fees
1 Feb - 2 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top James Island Hotel Reviews
Planters Inn
10/10 Excellent
Explore a world of travel with Expedia
- Ski Hotels in Coastal South Carolina
- Beach Hotels in Coastal South Carolina
- Cheap Hotels in North Charleston
- Cheap Hotels in Isle of Palms
- Pet Friendly Hotels in Isle of Palms
- Hotels with Pool in Downtown Charleston
- All Inclusive Hotels in Downtown Charleston
- Historic Hotels in Mount Pleasant
- Beach Hotels in Mount Pleasant
- Luxury Hotels in Summerville
- Lgbt Welcoming Hotels in Kiawah Island
- Cheap Hotels in Kiawah Island
- Family Hotels in Kiawah Island
- Beach Hotels in Kiawah Island
- Beach Hotels in Charleston
- Luxury Hotels in Charleston
- Spa Hotels in Charleston
- Romantic Hotels in Charleston
- Pet Friendly Hotels in Charleston
- Beach Hotels in West Ashley
- Beach Hotels in Sullivan's Island
- Luxury Hotels in Daniel Island
- Beach Hotels in Daniel Island
- Beach Hotels in Folly Beach
- Pet Friendly Hotels in Charleston Historic District
- Beach Hotels in Charleston Historic District
- Boutique Hotels in Charleston Historic District
- Charleston County Hotels
- Hotels near The Citadel
- French Quarter Hotels
- Hotels near Rainbow Row
- Charleston Historic District Hotels
- Old Village Hotels
- Sullivan's Island Hotels
- West Ashley Hotels
- Downtown Charleston Hotels
- Hotels near Cinebarre Mount Pleasant
- Hotels near Ashley Plaza Mall Shopping Center
- Harleston Village Hotels
- Hotels near Rainbow Market Shopping Center
- Charleston Hotels
- Folly Beach Hotels
- Resort in James Island
- Cabin Rentals in Morris Island
- Resort in Morris Island
- Condo Rentals in Folly Beach
- Holiday Homes in Folly Beach
- Cottages in Folly Beach
- Villas in Folly Beach
- B&B in Charleston
- Condo Rentals in Charleston
- Cottages in Charleston
- Serviced Apartments in Charleston
- Villas in Charleston
- Cabin Rentals in Charleston
- Motels in Charleston
- Villas in Sullivan's Island
- Inns in Sullivan's Island
- Resort in Mount Pleasant
- Marriott Hotels & Resorts in Charleston
- Sea Island Shopping Center
- Charleston Holidays
- Heyward-Washington House
- Shem Creek Park
- Aiken-Rhett House Museum
- Charleston Museum
- Angel Oak Tree
- White Point Gardens
- The Citadel
- Music Farm
- Pink House Gallery
- Orange Grove Plaza Shopping Center
- Charleston City Market
- Marion Square
- Visit Charleston Historic District
- Visit Charleston
- Visit Daniel Island
- Visit Secessionville Historic District
- Visit Riverland Terrace
- Visit Folly Beach
- Visit Radcliffeborough
- Visit James Island