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Grand Center Hotels, St. Louis

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Check prices for these dates

Tonight
9 Dec - 10 Dec
Tomorrow
10 Dec - 11 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for Grand Center hotels

Terrace/patio
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4.0 star property
Grand Center
8.8 out of 10, Excellent, (1038)
"This was a wonderful first experience at a beautiful hotel with such friendly staff. We will definitely stay here again!"
United States
Alexis
The price is NZ$243
includes taxes & fees
14 Dec - 15 Dec
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Comfort Apartment
White House at Grand Central

White House at Grand Central

4.0 star property
Grand Center
8.6 out of 10, Excellent, (124)
"Very clean and very friendly people "
United States
Mary
The price is NZ$251
includes taxes & fees
17 Dec - 18 Dec
White House at Grand Central
Front of property
Grand Center Inn

Grand Center Inn

3.0 star property
Grand Center
9.4 out of 10, Exceptional, (70)
"Great place"
United States
Nguyet
The price is NZ$318
includes taxes & fees
16 Dec - 17 Dec
Grand Center Inn
Rooftop terrace
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3.0 star property
Downtown St. Louis, 4.1 km from Grand Center
9.4 out of 10, Exceptional, (3279)
"Our stay was very enjoyable. Location was great and kids loved the indoor pool!"
United States
Christy
The price is NZ$273
includes taxes & fees
14 Dec - 15 Dec
Drury Plaza Hotel St. Louis at the Arch
Lobby
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 star property
16.2 km from Grand Center
9.4 out of 10, Exceptional, (2743)
"The room was clean and staff were very friendly."
United States
Denise
The price is NZ$183
includes taxes & fees
24 Dec - 25 Dec
Pear Tree Inn St. Louis Airport
Indoor pool
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3.0 star property
Downtown West, 2.4 km from Grand Center
9.4 out of 10, Exceptional, (1296)
"Great location and staff are friendly. "
United States
GARY
The price is NZ$245
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Inn & Suites St. Louis Union Station
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4.0 star property
Downtown St. Louis, 4.2 km from Grand Center
8.4 out of 10, Very good, (4019)
"Loved our stay. Great location and awesome view from room "
United States
Phillip
The price is NZ$193
includes taxes & fees
27 Dec - 28 Dec
Hyatt Regency St. Louis at The Arch
Lobby sitting area
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
23.3 km from Grand Center
8.0 out of 10, Very good, (1034)
"Very friendly staff "
United States
Amber
The price is NZ$170
includes taxes & fees
14 Dec - 15 Dec
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Exterior
Moonrise Hotel

Moonrise Hotel

4.0 star property
6.1 km from Grand Center
9.0 out of 10, Wonderful, (1922)
"Great service, unique hotel. Would absolutely stay again!"
United States
Michael
The price is NZ$259
includes taxes & fees
18 Dec - 19 Dec
Moonrise Hotel
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

4.0 star property
Downtown St. Louis, 3.8 km from Grand Center
8.8 out of 10, Excellent, (1241)
"Great hospitality"
United States
Alejandro
The price is NZ$221
includes taxes & fees
30 Dec - 31 Dec
Embassy Suites by Hilton St. Louis Downtown
Room, 2 Queen Beds, Accessible, Non Smoking (Mobility, Tub W/Grab Bars)
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

2.5 star property
16.2 km from Grand Center
9.2 out of 10, Wonderful, (1496)
"We enjoyed staying is very close to airport "
United States
Ellis
The price is NZ$220
includes taxes & fees
24 Dec - 25 Dec
Wingate by Wyndham St. Louis Airport
Interior
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 star property
Downtown West, 2.8 km from Grand Center
9.0 out of 10, Wonderful, (1489)
"Room was perfect and parking was a breeze. We really enjoyed the art was wonderful. "
United States
London
The price is NZ$265
includes taxes & fees
4 Jan - 5 Jan 2026
21C Museum Hotel St Louis
Breakfast, lunch and dinner served
Live by Loews - St.Louis

Live by Loews - St.Louis

4.0 star property
Downtown St. Louis, 3.8 km from Grand Center
9.4 out of 10, Exceptional, (1101)
"Great staff"
United States
Phillip
The price is NZ$307
includes taxes & fees
14 Dec - 15 Dec
Live by Loews - St.Louis
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4.0 star property
Downtown St. Louis, 3.7 km from Grand Center
8.8 out of 10, Excellent, (1145)
"So pleased with my stay would definitely recommend! Affordable and exclusive, staff ensured my stay was immaculate!"
United States
Meli
The price is NZ$208
includes taxes & fees
27 Dec - 28 Dec
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Lobby
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

3.0 star property
Downtown West, 3.1 km from Grand Center
8.0 out of 10, Very good, (594)
"A convenient location downtown with great rooms and services."
United States
Paul
The price is NZ$154
includes taxes & fees
17 Dec - 18 Dec
Home2 Suites by Hilton St. Louis Downtown
Room, 2 Queen Beds
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

2.5 star property
Downtown West, 3.1 km from Grand Center
7.6 out of 10, Good, (580)
"Everything great….very nice staff and security….delicious breakfast!!"
Canada
Derek
The price is NZ$164
includes taxes & fees
4 Jan - 5 Jan 2026
Tru By Hilton St. Louis Downtown
Suite, 1 Bedroom, City View | Living room
Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center

3.0 star property
Downtown St. Louis, 3.6 km from Grand Center
9.0 out of 10, Wonderful, (1003)
"Was a great stay. "
United States
Lorilyn
The price is NZ$208
includes taxes & fees
18 Dec - 19 Dec
Courtyard by Marriott St. Louis Downtown/Convention Center
Lobby
AC Hotel by Marriott St. Louis Chesterfield

AC Hotel by Marriott St. Louis Chesterfield

3.5 star property
29.5 km from Grand Center
9.2 out of 10, Wonderful, (237)
"Newer hotel, very clean, up to date and in nice area. "
United States
Johnny
The price is NZ$239
includes taxes & fees
21 Dec - 22 Dec
AC Hotel by Marriott St. Louis Chesterfield
Lobby
Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport

2.5 star property
20.2 km from Grand Center
8.0 out of 10, Very good, (1028)
"The room was great and the bed was very comfortable "
United States
Joyce
The price is NZ$199
includes taxes & fees
8 Jan - 9 Jan 2026
Best Western Plus St. Louis West-Westport
Exterior
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 star property
9.2 km from Grand Center
8.8 out of 10, Excellent, (3035)
"Very clean, friendly staff, great breakfast!"
United States
Stephen
The price is NZ$183
includes taxes & fees
14 Dec - 15 Dec
Clayton Plaza Hotel & Extended Stay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Our guide on where to stay in Grand Center

Find the best Grand Center areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Top Grand Center Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"Great staff , Tim was funny and fun to chat with. The breakfast and dinner were more than we expected. You even get 3 adult drinks "
Beau 5-night trip
Posted 17 hours ago
Drury Plaza Hotel St. Louis at the Arch

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Frequently asked questions

What's it like in Grand Center?
Grand Center is a neighbourhood that travellers like for its theatre scene and opera houses. Make sure that you visit Powell Symphony Hall and St. Louis Symphony Orchestra as part of your Grand Center travel plans.
Where is the best hotel for a stay in Grand Center?
Based on Expedia customer reviews, Grand Center Inn is the highest ranked property in Grand Center. This guest house offers free parking and private gardens. Another top choice in the area is Angad Arts Hotel St. Louis, Tapestry Collection by Hilton.
How many hotels will I find in Grand Center?
Expedia has 31 hotels and other accommodation options in Grand Center to choose from, making this an ideal home base for exploring the greater St. Louis area.
If I need to cancel my hotel reservation in Grand Center, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the best options available in Grand Center.
What are the top things to see and do in Grand Center?
While you're in Grand Center, you can catch a show at Powell Symphony Hall, St. Louis Symphony Orchestra and Sheldon Concert Hall. Fox Theater and Grandel Theater are also a couple of places to visit in the neighbourhood. St. Louis Union Station and Gateway Arch are some popular places to visit in the area around Grand Center. While you're out sightseeing in St. Louis, make sure that you visit other sights such as Urban League St. Louis or Vaughn Cultural Center.