Clayton Hotels, St. Louis

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Clayton hotels

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (562 reviews)
"Excellent hotel with various restaurants and expansive lobby area.. staff very attentive."
United States
Diane M
The price is NZ$1,019
includes taxes & fees
5 Apr - 6 Apr
The Ritz-Carlton, St. Louis

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (704 reviews)
"Clean room & good included breakfast "
United Kingdom
Felix
The price is NZ$295
includes taxes & fees
3 Apr - 4 Apr
Le Méridien St. Louis Clayton

AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton
3.0 star property
Clayton
9.0 out of 10, Wonderful, (268 reviews)
"Great location"
United States
Rolando
The price is NZ$294
includes taxes & fees
19 Apr - 20 Apr
AC Hotel St. Louis Clayton

Residence Inn By Marriott St. Louis Clayton

Residence Inn By Marriott St. Louis Clayton
3.0 star property
Clayton
9.2 out of 10, Wonderful, (210 reviews)
"Great location and staff"
United States
Matthew
The price is NZ$366
includes taxes & fees
5 Apr - 6 Apr
Residence Inn By Marriott St. Louis Clayton

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
Clayton
9.0 out of 10, Wonderful, (953 reviews)
"Clean, convenient, good breakfast. Nice workout room. Wish there was a pool outside, like a hot tub. Should have explained that you have to pay to park on-site. We did park less than a block away on the street for free."
United States
Anthony
The price is NZ$235
includes taxes & fees
12 Apr - 13 Apr
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Clayton
8.8 out of 10, Excellent, (3,139 reviews)
"Wonderful breakfast, easy and safe parking, comfortable beds, great shower!"
United States
Amy M.
The price is NZ$204
includes taxes & fees
19 Apr - 20 Apr
Clayton Plaza Hotel & Extended Stay

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Clayton
8.4 out of 10, Very good, (586 reviews)
"Rooms were very clean and the staff was friendly!"
United States
Deanna
The price is NZ$301
includes taxes & fees
19 Apr - 20 Apr
Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Homewood Suites by Hilton St Louis - Galleria

Homewood Suites by Hilton St Louis - Galleria
3.0 star property
Clayton
7.8 out of 10, Good, (1,004 reviews)
"I stayed for one night it was nice clean good breakfast "
United States
Doris
The price is NZ$254
includes taxes & fees
12 Apr - 13 Apr
Homewood Suites by Hilton St Louis - Galleria

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights
3.0 star property
29.7 km from Clayton
9.2 out of 10, Wonderful, (1,009 reviews)
"Staff was very welcoming and friendly. Breakfast was very good. Room was clean and comfortable. Excellent motel for the price. "
United States
MEDFORD
The price is NZ$186
includes taxes & fees
6 Apr - 7 Apr
Drury Inn & Suites St. Louis Fairview Heights

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
30.8 km from Clayton
8.4 out of 10, Very good, (833 reviews)
"Very friendly staff, comfortable room and convenient location "
United States
Aimee
The price is NZ$222
includes taxes & fees
26 Apr - 27 Apr
Comfort Inn Edwardsville - St. Louis

Days Inn by Wyndham Collinsville/St. Louis

Days Inn by Wyndham Collinsville/St. Louis
2.5 star property
27.3 km from Clayton
7.2 out of 10, Good, (1,002 reviews)
"For the most part when we travel, we are looking for a clean and safe place to sleep. I do not need a fancy facility with a beautiful pool and outstanding breakfast spread. This was definitely not a fancy hotel, but it was what we needed and served our purpose. The mgt at the Days Inn was friendly and courteous, and we had everything we needed to be comfortable. The location in Collinsville was great. "
United States
Michelle
The price is NZ$128
includes taxes & fees
13 Apr - 14 Apr
Days Inn by Wyndham Collinsville/St. Louis

Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach
3.0 star property
24.6 km from Clayton
8.6 out of 10, Excellent, (842 reviews)
"Room was very nice and breakfast had a good selection "
United States
Jonathon
The price is NZ$200
includes taxes & fees
19 Apr - 20 Apr
Best Western Plus Pontoon Beach

Casino Queen Hotel

Casino Queen Hotel
3.0 star property
13 km from Clayton
7.6 out of 10, Good, (2,038 reviews)
"Hotel staff was extremely helpful and friendly Room was clean"
United States
Kimberly
The price is NZ$170
includes taxes & fees
15 Apr - 16 Apr
Casino Queen Hotel

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 12 km from Clayton
8.8 out of 10, Excellent, (1,249 reviews)
"Loved my stay. Great location!"
United States
Rhonda
The price is NZ$250
includes taxes & fees
7 Apr - 8 Apr
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Missouri Athletic Club

Missouri Athletic Club
3.5 star property
Downtown St. Louis, 12 km from Clayton
8.8 out of 10, Excellent, (1,004 reviews)
"Hidden gem right next to the convention center. Staff was very accommodating and friendly. Clean and comfortable. Walking distance to most of downtown attractions and restaurants."
United States
Joseph
The price is NZ$320
includes taxes & fees
1 Apr - 2 Apr
Missouri Athletic Club

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 12 km from Clayton
8.4 out of 10, Very good, (3,995 reviews)
"Great hotel in a prime location."
United States
Preston
The price is NZ$349
includes taxes & fees
12 Apr - 13 Apr
Hyatt Regency St. Louis at The Arch

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 11.9 km from Clayton
8.8 out of 10, Excellent, (1,023 reviews)
"Great service and friendly staff!"
United States
Douglas
The price is NZ$235
includes taxes & fees
7 Apr - 8 Apr
Hilton Pennywell St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 11.9 km from Clayton
9.4 out of 10, Exceptional, (3,358 reviews)
"Great location and breakfast "
United States
Jenny
The price is NZ$368
includes taxes & fees
1 Apr - 2 Apr
Drury Plaza Hotel St. Louis at the Arch

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 11.7 km from Clayton
8.8 out of 10, Excellent, (1,298 reviews)
"Clean rooms, good breakfast, staff was fantastic!! "
United States
Christina
The price is NZ$251
includes taxes & fees
8 Apr - 9 Apr
Embassy Suites by Hilton St. Louis Downtown

Comfort Inn Collinsville near St. Louis

Comfort Inn Collinsville near St. Louis
2.5 star property
27.4 km from Clayton
8.6 out of 10, Excellent, (933 reviews)
"Clean, comfortable, and pleasant staff"
United States
Kathleen
The price is NZ$238
includes taxes & fees
13 Apr - 14 Apr
Comfort Inn Collinsville near St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Clayton

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Property amenity
AC Hotel St. Louis Clayton
3.0 star property
9.0
Wonderful
268 reviews
View
Outdoor dining
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
9.0
Wonderful
953 reviews
View
Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, pool loungers
Le Méridien St. Louis Clayton
4.0 star property
8.8
Excellent
704 reviews
View
Exterior
Clayton Plaza Hotel & Extended Stay
3.5 star property
8.8
Excellent
3,139 reviews
View
Lobby
Homewood Suites by Hilton St Louis - Galleria
3.0 star property
7.8
Good
1,004 reviews
View

Our guide on where to stay in Clayton

Find the best Clayton areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and Enterprise Center.

Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top Clayton Hotel Reviews

Frequently asked questions

What's it like in Clayton?
Clayton is a welcoming neighbourhood known for its array of dining options and sporting events. Make sure that you visit Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center as part of your Clayton travel plans.
Where is the best place to stay in Clayton?
Based on Expedia customer reviews, AC Hotel St. Louis Clayton is the highest ranked property in Clayton. This hotel offers 2 restaurants and 2 bars. Other top choices in the neighbourhood include Residence Inn By Marriott St. Louis Clayton and The Ritz-Carlton, St. Louis.
How many hotels will I find in Clayton?
Expedia has 20 hotels and other accommodation options in Clayton to choose from, making this an ideal home base for exploring the greater St. Louis area.
If I need to cancel my hotel reservation in Clayton, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the top deals on offer in Clayton.
What are the top things to see and do in Clayton?
A few attractions you might want to check out while you're in Clayton are Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. When you're sightseeing in St. Louis, St. Louis Zoo and Tao Tennis Center are also worth a stop.
How can I get around Clayton and the greater St. Louis area?
Ready to get out and explore the city? Clayton Station is the closest metro station.

Explore a world of travel with Expedia