Popular airlines
Alaska Airlines
Delta
American Airlines
United
Southwest Airlines
Frontier Airlines
JetBlue Airways
Be in the knowGet alerts if flight prices drop or rise*
Book smarterSave up to 35% on select hotels after you book a flight*
Cheapest flights from South San Diego
These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.
Tue, 26 May - Tue, 2 June
SAN
San Diego
SFO
San Francisco
NZ$218 Return, found 5 days ago
NZ$218
Return
found 5 days ago
Tue, 26 May - Tue, 2 June
SAN
San Diego
SFO
San Francisco
NZ$218 Return, found 5 days ago
NZ$218
Return
found 5 days ago
Thu, 28 May - Wed, 3 June
SAN
San Diego
LAS
Las Vegas
NZ$248 Return, found 3 days ago
NZ$248
Return
found 3 days ago
Thu, 28 May - Wed, 3 June
SAN
San Diego
LAS
Las Vegas
NZ$248 Return, found 3 days ago
NZ$248
Return
found 3 days ago
Tue, 26 May - Tue, 2 June
SAN
San Diego
SFO
San Francisco
NZ$253 Return, found 5 days ago
NZ$253
Return
found 5 days ago
Tue, 26 May - Tue, 2 June
SAN
San Diego
SFO
San Francisco
NZ$261 Return, found 5 days ago
NZ$261
Return
found 5 days ago
Tue, 26 May - Tue, 2 June
SAN
San Diego
SFO
San Francisco
NZ$262 Return, found 5 days ago
NZ$262
Return
found 5 days ago
Thu, 28 May - Wed, 3 June
SAN
San Diego
LAS
Las Vegas
NZ$265 Return, found 3 days ago
NZ$265
Return
found 3 days ago
Tue, 26 May - Tue, 2 June
SAN
San Diego
SFO
San Francisco
NZ$269 Return, found 5 days ago
NZ$269
Return
found 5 days ago
Thu, 28 May - Wed, 3 June
SAN
San Diego
LAS
Las Vegas
NZ$317 Return, found 3 days ago
NZ$317
Return
found 3 days ago
Explore a world of travel with Expedia
- Boutique Hotels in South Bay
- Cheap Hotels in Otay Mesa
- Family Hotels in South San Diego
- Beach Hotels in South San Diego
- Romantic Hotels in South San Diego
- Beach Hotels in San Diego Coast
- All Inclusive Hotels in San Diego Coast
- Cheap Hotels in San Diego Coast
- B&B in San Diego Coast
- B&B in Chula Vista
- Residences in Chula Vista
- Apartments in Chula Vista
- Hostels in San Ysidro
- Cottages in National City
- Villas in South Bay
- Cottages in South Bay
- Apartments in South Bay
- Serviced Apartments in South Bay
- Holiday Homes in South Bay
- Guest Houses in South Bay
- Motels in Encanto - 62nd St Trolley Station
- Apartments in Imperial Beach
- Holiday Homes in Imperial Beach
- Best Western Hotels in San Ysidro
- Otay Hotels
- Hotels near Len Moore Skate Park
- Chula Vista Hotels
- Otay Mesa Hotels
- San Ysidro Hotels
- Nestor Hotels
- Hotels near Brown Field Municipal
- Otay Mesa West Hotels
- Imperial Beach Hotels
- Hotels near Palm Ave Trolley Station
- Bonita Hotels
- Eastlake Hotels
- Hotels near Sky Zone San Diego Indoor Trampoline Park
- Hotels near San Ysidro Border Crossing
- National City Hotels
- Hotels near Chula Vista Elite Athlete Training Center
- Flights from Brown Field Municipal
- Flights to San Ysidro
- Flights to National City
- Flights to Chula Vista
- Flights from La Mesa
- Flights from Spring Valley
- Flights from Lemon Grove
- Flights from La Jolla
- Flights from San Diego
- Flights from El Cajon
- Flights from Fairbanks Ranch
- Flights from Sydney (SYD) to San Diego (SDM)
- Flights from Hartford (BDL) to San Diego (SDM)
- Flights from Long Beach (LGB) to San Diego (SDM)
- Flights from Henderson (HSH) to San Diego (SDM)
- Flights from Hong Kong (HKG) to San Diego (SDM)
- Flights from Las Vegas (LAS) to San Diego (SDM)
- Flights from Los Angeles (LAX) to San Diego (SDM)
- Flights from Orange County (SNA) to San Diego (SDM)
- Flights from Houston (IAH) to San Diego (SDM)
- Flights from Denver (DEN) to San Diego (SDM)
- Flights from Boston (BOS) to San Diego (SDM)
- Flights from San Francisco (SFO) to San Diego (SDM)
- San Ysidro Border Crossing
- Silver Strand State Beach
- Sharp Chula Vista Medical Center
- Chula Vista Center
- San Diego-Coronado Bridge
- Chula Vista Elite Athlete Training Center
- North Island Credit Union Amphitheatre
- Kaiser Permanente Otay Mesa Medical Offices
- Atlantis Laser Tag
- Las Americas Premium Outlets
- Visit Otay Mesa
- Visit Encanto
- Visit Chula Vista
- Visit Otay Mesa West
- Visit Bonita
- Visit National City
- Visit Rancho del Rey
- Visit Otay
- Visit Bay Terraces
- Sixt Rental Cars in San Diego Coast
- Mex Rent A Car Rental Cars in San Diego Coast
- Fox Rental Cars Rental Cars in Chula Vista
- Midway Car Rental Rental Cars in South Bay
- Avis Rental Cars in South San Diego
- Addcar rental Rental Cars in South San Diego
- Hertz Rental Cars in South San Diego
- Centauro Rental Cars in South San Diego
- Car hire Bonita
- Car hire Chula Vista
*Available to Expedia members.