Serra Mesa Hotels, San Diego

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Our top choices for Serra Mesa hotels

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
6.4 km from Serra Mesa
8.0 out of 10, Very good, (1,004 reviews)
"Great stay"
United States
Viviann
The price is NZ$185
includes taxes & fees
8 Mar - 9 Mar
Crowne Plaza San Diego - Mission Valley by IHG

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
28.1 km from Serra Mesa
9.0 out of 10, Wonderful, (1,213 reviews)
"Great stay"
United States
Elisa
The price is NZ$217
includes taxes & fees
16 Feb - 17 Feb
Best Western Americana Inn

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
5.3 km from Serra Mesa
9.4 out of 10, Exceptional, (1,470 reviews)
"Stunning hotel, I could have stayed there all day looking at every little design detail. "
United States
Holly
The price is NZ$435
includes taxes & fees
17 Feb - 18 Feb
Lafayette Hotel & Club

The Sands of La Jolla

The Sands of La Jolla
2.5 star property
12 km from Serra Mesa
9.0 out of 10, Wonderful, (747 reviews)
"Great location and nice area."
United States
Gary
The price is NZ$232
includes taxes & fees
16 Feb - 17 Feb
The Sands of La Jolla

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.8 km from Serra Mesa
9.2 out of 10, Wonderful, (1,733 reviews)
"Very clean resort. "
United States
Petrina
Sycuan Casino Resort

Bahia Resort Hotel

Bahia Resort Hotel
3.5 star property
Central Mission Beach, 10.7 km from Serra Mesa
8.6 out of 10, Excellent, (1,881 reviews)
"Amazing place "
United States
Richard
The price is NZ$382
includes taxes & fees
1 Mar - 2 Mar
Bahia Resort Hotel

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.1 km from Serra Mesa
9.2 out of 10, Wonderful, (3,728 reviews)
"My favorite place to stay"
United States
Rubidia
The price is NZ$232
includes taxes & fees
16 Feb - 17 Feb
Best Western Plus Marina Gateway Hotel

Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
3.0 star property
8.2 km from Serra Mesa
9.2 out of 10, Wonderful, (633 reviews)
"Great place to stay, nice room Highly recommended !!"
United States
Wilfredo
The price is NZ$225
includes taxes & fees
22 Feb - 23 Feb
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 7.2 km from Serra Mesa
8.4 out of 10, Very good, (1,349 reviews)
"Great place for our family getaway! Loved the S’mores on the beach! "
United States
Dani
The price is NZ$466
includes taxes & fees
1 Mar - 2 Mar
San Diego Mission Bay Resort

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4,152 reviews)
"Good location friendly staff"
United States
Anya
The price is NZ$161
includes taxes & fees
22 Feb - 23 Feb
Wyndham Garden San Diego Near SeaWorld

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
7.9 km from Serra Mesa
9.2 out of 10, Wonderful, (1,055 reviews)
"great stay"
United States
Jose
The price is NZ$259
includes taxes & fees
22 Feb - 23 Feb
Holiday Inn Express San Diego Airport - Old Town by IHG

Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
25.1 km from Serra Mesa
7.8 out of 10, Good, (1,615 reviews)
"Clean rooms and the breakfast was amazing "
United States
Vanessa
The price is NZ$188
includes taxes & fees
16 Feb - 17 Feb
Best Western Chula Vista/Otay Valley Hotel

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (1,932 reviews)
"Great stay"
United States
Lizeth
The price is NZ$168
includes taxes & fees
22 Feb - 23 Feb
GreenTree Inn San Diego Mission Bay

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
9.9 km from Serra Mesa
8.4 out of 10, Very good, (6,039 reviews)
"Great place to stay"
United States
David
The price is NZ$350
includes taxes & fees
1 Mar - 2 Mar
Wyndham San Diego Bayside

Old Town Inn

Old Town Inn
2.5 star property
8.1 km from Serra Mesa
9.2 out of 10, Wonderful, (1,801 reviews)
"Clean, friendly staff, good value, nice pool area"
Canada
Mark
The price is NZ$241
includes taxes & fees
16 Feb - 17 Feb
Old Town Inn

SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
23.9 km from Serra Mesa
9.6 out of 10, Exceptional, (581 reviews)
"Clean room and friendly staff "
United States
Michael
The price is NZ$328
includes taxes & fees
15 Mar - 16 Mar
SpringHill Suites by Marriott Chula Vista Eastlake

Ash&9th

Ash&9th
2.0 star property
9.4 km from Serra Mesa
8.4 out of 10, Very good, (341 reviews)
"Great location… stuff was really friendly "
United States
Aurora
The price is NZ$154
includes taxes & fees
9 Mar - 10 Mar
Ash&9th

Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,635 reviews)
"Very easy vacation, convenient breakfast as well as location."
United States
Kathy
The price is NZ$389
includes taxes & fees
1 Mar - 2 Mar
Embassy Suites by Hilton San Diego Bay Downtown

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay, 9.9 km from Serra Mesa
8.6 out of 10, Excellent, (2,416 reviews)
"Clean Rooms, staff very friendly, very relaxing place "
United States
AlmaDelia
The price is NZ$385
includes taxes & fees
1 Mar - 2 Mar
Paradise Point Resort & Spa

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
12.9 km from Serra Mesa
8.8 out of 10, Excellent, (1,591 reviews)
"Great place.very clean great for family would definitely stay there again."
United States
Joseph
The price is NZ$257
includes taxes & fees
16 Feb - 17 Feb
Best Western Plus Island Palms Hotel & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Seaport Village and Petco Park are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach and Dog Beach.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 39 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

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