Serra Mesa Hotels, San Diego

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17 Nov - 18 Nov
Tomorrow
18 Nov - 19 Nov
This weekend
21 Nov - 23 Nov
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28 Nov - 30 Nov

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8953 Cheap Hotels in Serra Mesa - Specials, Reviews, & Last Minute Deals

Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 star property
9.9 km from Serra Mesa
8.4 out of 10, Very good, (6048)
"I enjoyed my stay."
United States
Kevin
The price is NZ$327
includes taxes & fees
23 Nov - 24 Nov
Wyndham San Diego Bayside
Outdoor pool
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4.0 star property
Gaslamp Quarter, 10.8 km from Serra Mesa
9.0 out of 10, Wonderful, (3079)
"Our stay was great! Would stay here again"
United States
Carla
The price is NZ$409
includes taxes & fees
8 Dec - 9 Dec
Hard Rock Hotel San Diego
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed)
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 star property
16.1 km from Serra Mesa
9.2 out of 10, Wonderful, (3406)
"Clean, staff friendly, great place for a stay"
United States
Derrick
The price is NZ$225
includes taxes & fees
23 Nov - 24 Nov
Best Western Plus Marina Gateway Hotel
Rooftop terrace
Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 10.1 km from Serra Mesa
8.6 out of 10, Excellent, (2034)
"Clean room, excellent staff and pleasant atmosphere "
United States
Estela
The price is NZ$235
includes taxes & fees
23 Nov - 24 Nov
Palihotel San Diego Gaslamp Quarter
Exterior
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
Gaslamp Quarter, 10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1208)
"Clean room ,friendly staff, great location "
United States
Jessica
The price is NZ$276
includes taxes & fees
19 Nov - 20 Nov
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Serves dinner and happy hour
The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
10.5 km from Serra Mesa
9.0 out of 10, Wonderful, (2656)
"Very nice location and rooms. "
United States
David
The Horton Grand, Downtown/Gaslamp Quarter
Lobby
El Cordova Hotel on Coronado Island

El Cordova Hotel on Coronado Island

3.5 star property
13.9 km from Serra Mesa
8.8 out of 10, Excellent, (1004)
"Thank you - great spot! I will stay again ⭐️ "
United States
Donna
The price is NZ$324
includes taxes & fees
30 Nov - 1 Dec
El Cordova Hotel on Coronado Island
Garden
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4.0 star property
5.7 km from Serra Mesa
9.2 out of 10, Wonderful, (2937)
"Great hotel"
United States
Michael
The price is NZ$356
includes taxes & fees
17 Dec - 18 Dec
Legacy Resort Hotel & Spa
Property entrance
The Bristol Hotel San Diego

The Bristol Hotel San Diego

3.5 star property
9.9 km from Serra Mesa
8.6 out of 10, Excellent, (1429)
"Nice staff, comfortable beds"
United States
Amber
The Bristol Hotel San Diego
Lobby
Gaslamp Plaza Suites

Gaslamp Plaza Suites

3.5 star property
Gaslamp Quarter, 10 km from Serra Mesa
8.8 out of 10, Excellent, (1005)
"An extremely clean and well kept vintage property. I loved the traditional hotel qualities, mended with modern amenities. A repeat stay is probable. "
United States
Paul
The price is NZ$222
includes taxes & fees
9 Dec - 10 Dec
Gaslamp Plaza Suites
Front of property
The Sofia Hotel

The Sofia Hotel

3.5 star property
10 km from Serra Mesa
8.4 out of 10, Very good, (1632)
"Excellent stay all-around!"
United States
Nalani
The Sofia Hotel
Outdoor pool, a heated pool
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
5.4 km from Serra Mesa
8.0 out of 10, Very good, (2398)
"We loved our stay, great price, very clean and excellent location! "
United States
Brenda
The price is NZ$179
includes taxes & fees
23 Nov - 24 Nov
Days Inn by Wyndham San Diego Hotel Circle
2 outdoor pools, a heated pool, pool loungers
The Dana on Mission Bay

The Dana on Mission Bay

3.5 star property
Mission Bay, 10.1 km from Serra Mesa
8.8 out of 10, Excellent, (3865)
"Overall, nice place to stay!"
United States
Jazmine
The price is NZ$357
includes taxes & fees
23 Nov - 24 Nov
The Dana on Mission Bay
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
Gaslamp Quarter, 10.4 km from Serra Mesa
9.4 out of 10, Exceptional, (1003)
"The room was immaculate, the staff were helpful and friendly and our stay was so wonderful. "
United States
Samantha Erin
The price is NZ$270
includes taxes & fees
24 Nov - 25 Nov
Staypineapple, Hotel Z, Gaslamp San Diego
2 outdoor pools, open 6 AM to 10:00 PM, pool cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4.0 star property
10.7 km from Serra Mesa
9.2 out of 10, Wonderful, (1914)
"The hotel was beautiful and the staff was amazingly kind, warm, and accommodating!"
United States
Leila
The price is NZ$417
includes taxes & fees
23 Nov - 24 Nov
Marriott Marquis San Diego Marina
Check-in/check-out kiosk
Urban Boutique Hotel

Urban Boutique Hotel

3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1279)
"Alwsys clean , great staff andvperfect location"
United States
Colleen
Urban Boutique Hotel
Exterior
La Pensione Hotel

La Pensione Hotel

3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1898)
"Friendly staff, very nice room, great location!"
United States
Lisa
La Pensione Hotel
Standard Room, 1 King Bed, Non Smoking, Bay View
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
9.3 km from Serra Mesa
8.8 out of 10, Excellent, (656)
"Great staff, great location, great value. "
United States
Juan
The price is NZ$183
includes taxes & fees
14 Dec - 15 Dec
The DEXTRO Little Italy, BW Premier Collection
City view from property
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4.0 star property
Little Italy, 9.3 km from Serra Mesa
8.2 out of 10, Very good, (1224)
"Beautiful hotel ."
United States
Emiliano
The price is NZ$224
includes taxes & fees
23 Nov - 24 Nov
Courtyard by Marriott San Diego Downtown Little Italy
3 outdoor pools, pool cabanas (surcharge), pool umbrellas
Sycuan Casino Resort

Sycuan Casino Resort

4.0 star property
29.1 km from Serra Mesa
9.2 out of 10, Wonderful, (1610)
"Nice hotel and friendly staff. Will definitely stay again ."
United States
Lorna
Sycuan Casino Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels in Serra Mesa with free breakfast

Terrace/patio
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4.0 star property
  • Breakfast included
8.4 out of 10, Very good, (6048)
The price is NZ$327
includes taxes & fees
23 Nov - 24 Nov
Wyndham San Diego Bayside
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Hotels in Serra Mesa with a pool

Suite, 1 King Bed with Sofa bed, City View | View from room
Marriott Vacation Club®, San Diego
Marriott Vacation Club®, San Diego
3.5 star property
  • Pool
9.4 out of 10, Exceptional, (1006)
The price is NZ$275
includes taxes & fees
14 Dec - 15 Dec
Marriott Vacation Club®, San Diego
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Top guest rated hotels in Serra Mesa

Standard Room, 1 King Bed, Non Smoking, Bay View
The DEXTRO Little Italy, BW Premier Collection
The DEXTRO Little Italy, BW Premier Collection
3.0 star property
    8.8 out of 10, Excellent, (656)
    The price is NZ$183
    includes taxes & fees
    14 Dec - 15 Dec
    The DEXTRO Little Italy, BW Premier Collection
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    Our guide on where to stay in Serra Mesa

    Find the best Serra Mesa areas for the activities you enjoy most.

    Downtown San Diego

    Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

    Gaslamp Quarter featuring a bar, street scenes and a city

    Gaslamp Quarter

    The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

    Pacific Beach Park featuring a beach

    Pacific Beach

    Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

    Belmont Park which includes a garden and rides

    Mission Beach

    If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

    Ocean Beach

    Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

    Top Serra Mesa Hotel Reviews

    Comfort Inn Sea World Area

    Comfort Inn Sea World Area

    10/10 Excellent
    "Clean room, good amenities a great location for the airport"
    Romina 1-night trip
    Posted 1 day ago
    Comfort Inn Sea World Area

    Explore a world of travel with Expedia

    Frequently asked questions

    What's it like in Serra Mesa?
    Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
    How many hotels can I expect to find in the Serra Mesa area?
    Expedia has 37 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
    If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
    Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
    What can I see and do in this San Diego neighbourhood?
    Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.