Serra Mesa Hotels, San Diego

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2 Oct - 3 Oct
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8927 Cheap Hotels in Serra Mesa - Specials, Reviews, & Last Minute Deals

Wyndham San Diego Bayside
Terrace/patio

Wyndham San Diego Bayside

4.0 star property
8.4 out of 10, Very good, (5952)
"Great stay near the airport."
The price is NZ$353
includes taxes & fees
5 Oct - 6 Oct
Wyndham San Diego Bayside
Hard Rock Hotel San Diego
Outdoor pool

Hard Rock Hotel San Diego

4.0 star property
9.0 out of 10, Wonderful, (2971)
"Loved staying here. Will definitely stay again "
The price is NZ$536
includes taxes & fees
22 Oct - 23 Oct
Hard Rock Hotel San Diego
Palihotel San Diego Gaslamp Quarter
Rooftop terrace

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.8 out of 10, Excellent, (1866)
"would definitely stay again!"
The price is NZ$231
includes taxes & fees
23 Oct - 24 Oct
Palihotel San Diego Gaslamp Quarter
Loews Coronado Bay Resort
Exterior

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1036)
"Beautiful quiet hotel."
The price is NZ$458
includes taxes & fees
26 Oct - 27 Oct
Loews Coronado Bay Resort
Best Western Plus Marina Gateway Hotel
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed)

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3292)
"Great hotel"
The price is NZ$263
includes taxes & fees
5 Oct - 6 Oct
Best Western Plus Marina Gateway Hotel
Ramada Suites by Wyndham San Diego/Hotel Circle Area
Outdoor pool

Ramada Suites by Wyndham San Diego/Hotel Circle Area

2.5 star property
6.2 out of 10, (1007)
"comfortable, easy access, friendly staff"
The price is NZ$132
includes taxes & fees
5 Oct - 6 Oct
Ramada Suites by Wyndham San Diego/Hotel Circle Area
Gaslamp Plaza Suites
Lobby

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1004)
"Had a great stay "
The price is NZ$211
includes taxes & fees
6 Oct - 7 Oct
Gaslamp Plaza Suites
The Horton Grand, Downtown/Gaslamp Quarter
Serves dinner and happy hour

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2576)
"Great location and lovely staff. "
The Horton Grand, Downtown/Gaslamp Quarter
The Sofia Hotel
Front of property

The Sofia Hotel

3.5 star property
8.4 out of 10, Very good, (1588)
"Fantastic staff and property. "
The Sofia Hotel
El Cordova Hotel on Coronado Island
Lobby

El Cordova Hotel on Coronado Island

3.5 star property
8.8 out of 10, Excellent, (1003)
"We love this hotel. It gives a feel of having your own apartment on the island. The rooms is are clean and comfortable. The staff is welcoming and accommodating. The location is perfect. Close walking distance to the beach, dining, shopping, as well as the famous Del across the street. "
El Cordova Hotel on Coronado Island
The Bristol Hotel San Diego
Property entrance

The Bristol Hotel San Diego

3.5 star property
8.4 out of 10, Very good, (1385)
"Pleasant stay"
The Bristol Hotel San Diego
Legacy Resort Hotel & Spa
Garden

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2876)
"Great stay overall"
The price is NZ$326
includes taxes & fees
5 Oct - 6 Oct
Legacy Resort Hotel & Spa
La Pensione Hotel
Exterior

La Pensione Hotel

3.0 star property
8.6 out of 10, Excellent, (1895)
"Great place to stay they are right in the middle of everything "
La Pensione Hotel
Days Inn by Wyndham San Diego Hotel Circle
Outdoor pool, a heated pool

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
8.0 out of 10, Very good, (2341)
"We loved our stay, great price, very clean and excellent location! "
The price is NZ$194
includes taxes & fees
5 Oct - 6 Oct
Days Inn by Wyndham San Diego Hotel Circle
The Dana on Mission Bay
2 outdoor pools, a heated pool, pool loungers

The Dana on Mission Bay

3.5 star property
8.8 out of 10, Excellent, (3746)
"Great stay and great location "
The price is NZ$301
includes taxes & fees
26 Oct - 27 Oct
The Dana on Mission Bay
Staypineapple, Hotel Z, Gaslamp San Diego
Premium bedding, pillow-top beds, desk, blackout curtains

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
9.4 out of 10, Exceptional, (1000)
"Great staff and clean rooms"
The price is NZ$346
includes taxes & fees
22 Oct - 23 Oct
Staypineapple, Hotel Z, Gaslamp San Diego
Glorietta Bay Inn Coronado Island
Front of property – evening/night

Glorietta Bay Inn Coronado Island

3.5 star property
8.6 out of 10, Excellent, (1000)
"Great location"
The price is NZ$451
includes taxes & fees
8 Oct - 9 Oct
Glorietta Bay Inn Coronado Island
Days Inn by Wyndham San Diego-East/El Cajon
Standard Room, 1 King Bed, Smoking

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1002)
"Place was nice and comfy. Decent stay at a very genuine price. "
The price is NZ$150
includes taxes & fees
9 Oct - 10 Oct
Days Inn by Wyndham San Diego-East/El Cajon
Urban Boutique Hotel
Check-in/check-out kiosk

Urban Boutique Hotel

3.0 star property
8.6 out of 10, Excellent, (1246)
"Great hotel and excellent location!"
The price is NZ$215
includes taxes & fees
12 Oct - 13 Oct
Urban Boutique Hotel
Bay Club Hotel & Marina
Exterior

Bay Club Hotel & Marina

3.5 star property
9.0 out of 10, Wonderful, (2978)
"Fantastic location, friendly staff great rooms"
The price is NZ$272
includes taxes & fees
6 Oct - 7 Oct
Bay Club Hotel & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring a bar, street scenes and a city

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach Park featuring a beach

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Belmont Park which includes a garden and rides

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Serra Mesa Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"It was centrally located,. I had private car and they had parking in. It was perfect for me, the rooms were comfortable and clean. Pretty view."
Milagros 3-night trip
Posted 1 day ago
The DEXTRO Little Italy, BW Premier Collection

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels can I expect to find in the Serra Mesa area?

Expedia has 34 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.

What can I see and do in this San Diego neighbourhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.