
Serra Mesa Holidays
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Our guide on where to stay in Serra Mesa
Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Serra Mesa

Downtown San Diego
2 out of top 10 points of interest in this area
4.5/5(100 area reviews)
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Our pick of the best Serra Mesa Hotel Deals

Handlery Hotel
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
8/10 Very Good! (1,859 reviews)
"Needs serious updating"
Reviewed on 10 Jul. 2025

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is NZ$340 per night from 20 July to 21 July
NZ$340
20 July - 21 July
includes taxes & fees
8.2/10 Very Good! (5,698 reviews)
"Would come again."
Reviewed on 8 Jul. 2025

Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is NZ$426 per night from 20 July to 21 July
NZ$426
20 July - 21 July
includes taxes & fees
8.8/10 Excellent! (2,769 reviews)
"Overall great experience. Only downside is everyone can access property, cleanliness wasn’t top tier."
Reviewed on 9 Jul. 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Serra Mesa

San Diego Zoo
4.5/5(26 reviews)
Admire the animal kingdom in all its fascinating glory at one of America’s largest zoos.

Mission Bay
4/5(10 reviews)
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.

Petco Park
4.5/5(10 reviews)
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Activities

San Diego's City Harbor Sightseeing Cruise
NZ$58
per adult
90% of travellers recommend

San Diego SEAL Tour by Land & Sea
NZ$76
per adult
92% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.