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Our top choices for Saint James City hotels

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
Saint James City
9.6 out of 10, Exceptional, (160 reviews)
"second floor with the screened in porch was fabulous! Loved the hanging chair and we had a full view of all of the manatee's outback! Perfectly located, will stay here again for sure!~"
United States
Kevin
The price is NZ$349
includes taxes & fees
28 May - 29 May
Off the Charts Inn & Out Island Resort

HomeTowne Studios by Red Roof Fort Myers

HomeTowne Studios by Red Roof Fort Myers
2.5 star property
Fort Myers
The price is NZ$118
includes taxes & fees
25 May - 26 May
HomeTowne Studios by Red Roof Fort Myers

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
Fort Myers Beach
9.0 out of 10, Wonderful, (1,487 reviews)
"Beach view fabulous, all the staff was very helpful and polite "
United States
Shari
The price is NZ$305
includes taxes & fees
26 May - 27 May
Lani Kai Beachfront Resort

Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
Daniels Corridor
9.6 out of 10, Exceptional, (1,032 reviews)
"Very nice stay"
United States
James
The price is NZ$185
includes taxes & fees
3 June - 4 June
Holiday Inn Express & Suites Fort Myers Airport by IHG

Comfort Suites Fort Myers East I-75

Comfort Suites Fort Myers East I-75
2.5 star property
Fort Myers
9.6 out of 10, Exceptional, (458 reviews)
"Great place to stay"
United States
Dennis
The price is NZ$165
includes taxes & fees
7 June - 8 June
Comfort Suites Fort Myers East I-75

TownePlace Suites by Marriott Fort Myers Gulf Coast

TownePlace Suites by Marriott Fort Myers Gulf Coast
3.0 star property
Fort Myers
9.2 out of 10, Wonderful, (197 reviews)
"Such fantastic staff"
United States
Emily
The price is NZ$200
includes taxes & fees
12 June - 13 June
TownePlace Suites by Marriott Fort Myers Gulf Coast

Extended Stay America Premier Suites - Fort Myers - Airport

Extended Stay America Premier Suites - Fort Myers - Airport
2.5 star property
Daniels Corridor
8.8 out of 10, Excellent, (981 reviews)
"very nice place to stay!"
United States
Natalia
The price is NZ$111
includes taxes & fees
24 May - 25 May
Extended Stay America Premier Suites - Fort Myers - Airport

Hampton Inn & Suites Fort Myers-Estero/FGCU

Hampton Inn & Suites Fort Myers-Estero/FGCU
2.5 star property
Estero
9.2 out of 10, Wonderful, (1,001 reviews)
"Nice hotel."
United States
Irinel
The price is NZ$159
includes taxes & fees
11 June - 12 June
Hampton Inn & Suites Fort Myers-Estero/FGCU

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
2.0 star property
Daniels Corridor
8.0 out of 10, Very good, (1,689 reviews)
"very clean, nice and pretty hotel!"
United States
Natalia
The price is NZ$138
includes taxes & fees
17 May - 18 May
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
Fort Myers
8.2 out of 10, Very good, (1,144 reviews)
"Clean room, nice pool, near beaches, good breakfast."
United States
Kenneth
The price is NZ$142
includes taxes & fees
9 June - 10 June
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
Fort Myers
8.8 out of 10, Excellent, (1,000 reviews)
"Wonderful location and accommodations!"
United States
Karen
The price is NZ$193
includes taxes & fees
14 May - 15 May
Residence Inn by Marriott Fort Myers Sanibel

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
8.8 out of 10, Excellent, (1,002 reviews)
"Amazing place to stay! "
United States
Kristen
The price is NZ$178
includes taxes & fees
14 May - 15 May
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island
10.0 out of 10, Exceptional, (35 reviews)
"We had a great time and would definitely stay there again!"
United States
William Edward
The price is NZ$393
includes taxes & fees
31 May - 1 June
The Anchor Inn

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
Fort Myers Beach
9.2 out of 10, Wonderful, (1,014 reviews)
"The staff from check-in to check-out was super friendly. The complimentary breakfast was great.The room was clean and inviting. Great place to stay at a great price. Close to Fort Myers beach"
United States
LISA
The price is NZ$174
includes taxes & fees
21 May - 22 May
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Quality Suites Fort Myers I-75

Quality Suites Fort Myers I-75
2.5 star property
Daniels Corridor
8.4 out of 10, Very good, (1,003 reviews)
"Great hotel! Comfortable clean and safe area!"
United States
Coltin
The price is NZ$123
includes taxes & fees
7 June - 8 June
Quality Suites Fort Myers I-75

Drury Inn & Suites Fort Myers Airport FGCU

Drury Inn & Suites Fort Myers Airport FGCU
4.0 star property
Miromar Lakes
9.6 out of 10, Exceptional, (1,001 reviews)
"Great staff easy check in property in great shape "
United States
Craig
The price is NZ$206
includes taxes & fees
17 May - 18 May
Drury Inn & Suites Fort Myers Airport FGCU

Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers
3.0 star property
Fort Myers
7.6 out of 10, Good, (1,241 reviews)
"The rooms are really nice and affordable and I was pleased...."
United States
James
The price is NZ$126
includes taxes & fees
20 May - 21 May
Americas Best Value Inn Ft. Myers

Hampton Inn Fort Myers-Airport & I-75

Hampton Inn Fort Myers-Airport & I-75
3.5 star property
Daniels Corridor
9.0 out of 10, Wonderful, (1,000 reviews)
"Excellent stay. Great staff. Clean"
United States
Anthony
The price is NZ$182
includes taxes & fees
24 May - 25 May
Hampton Inn Fort Myers-Airport & I-75

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island
9.2 out of 10, Wonderful, (1,888 reviews)
"Loved the room and the location, the grounds were beautiful and had a convenient beach access, very charming!"
United States
Hillary
The price is NZ$454
includes taxes & fees
4 June - 5 June
Sanibel Island Beach Resort

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
Villas
8.6 out of 10, Excellent, (869 reviews)
"Staff very friendly. Fabulous breakfast. Clean and very nice hotel"
United States
michael
The price is NZ$167
includes taxes & fees
27 May - 28 May
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Saint James City

Find the best Saint James City areas for the activities you enjoy most.

Manatee Bay

Though Manatee Bay may not have many top sights, you can venture to the surrounding area to see attractions like Harbour View Gallery and Chabad Jewish Center.

Learn more about Saint James City

Rent a boat to explore Pine Island's mangrove-lined waterways where dolphins often play alongside fishing enthusiasts. Savour fresh-caught seafood at waterfront restaurants while watching spectacular Gulf Coast sunsets that paint the sky in vibrant colours.

Sunset on the southern end of Pine Island, Florida.

Top Saint James City Hotel Reviews

More cheap accommodation in Saint James City

Frequently asked questions

Where is the best place for a stay in Saint James City?
Based on Expedia's traveller preferences, Off the Charts Inn & Out Island Resort is a top place to stay in Saint James City. Two other choices for your trip to the area are Margaritaville Beach Resort Fort Myers and Sanibel Island Beach Resort. See all available top hotels, or vacation rentals in Saint James City.
What are some of the best holiday rentals that Saint James City has to offer?
North Captiva Point House - Boat/Water Taxi Only NEWLY RENOVATED : This holiday home rental outside of Saint James City is located on the beach, and has a balcony, a BBQ and air conditioning to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in Saint James City.
If I need to cancel my hotel reservation in Saint James City, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Saint James City.
What's the best dog-friendly accommodation option in Saint James City?
Off the Charts Inn & Out Island Resort is a top dog-friendly option for your stay. Other good choices for you and your pet include Off the Charts Inn - Queen Double Room and Off the Charts Inn - King Suite. See more pet-friendly hotel accommodations in Saint James City.
What are some hotels with pools in Saint James City?
Margaritaville Beach Resort Fort Myers: Hotel, 2-minute walk from Estero Boulevard Beach. Offers 4 restaurants, an outdoor pool and a full-service spa. Sanibel Island Beach Resort and Lani Kai Beachfront Resort are a couple of other choices that feature an on-site pool. View all hotels with pools in Saint James City.
What's it like to stay in Saint James City?
Visitors can enjoy all that Saint James City has to offer, including its seafood restaurants. This city also attracts tourists with its relaxing setting. In Saint James City, there are 197 hotels and other accommodation options to choose from. Find out more about Saint James City.
What should I see while I'm in Saint James City?
Places to visit in the wider area include J. N. Ding Darling National Wildlife Refuge, Causeway Islands Park B and Periwinkle Way. You'll also find Sanibel Harbour and Sanibel Harbour Beach in the area. Take a look at what more there is to see and do in Expedia's Saint James City guide.
What's the seasonal weather in Saint James City?
The hottest months are usually August and July, with an average temperature of 28°C, while the coldest months are January and February, with an average of 20°C. The rainiest months in Saint James City are August, June, September and July, with each month seeing an average of 178 mm of rainfall.

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