Photo by Anthony Hilario

Plan, book, travel with confidence
Better together
Save up to NZ$2,400 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Mountain San Luis Obispo Wine Country Hotels

San Luis Inn And Suites

404 Santa Rosa St San Luis Obispo CA

18 min walk from California Polytechnic State University

Stay at this motel in San Luis Obispo. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the clean rooms in their reviews. Popular attractions ...

7.2/10 Good! (346 reviews)

Workers were really nice and welcoming. The room was nice. Property was okay-maintained. Some positives is that there are lot of food places near the hotel, right next to 101 freeway and close to downtown. Neighborhood is okay but you still feel fairly safe. Beds were good and bathroom. A solid ...

Reviewed on 11 May 2026

Madonna Inn

100 Madonna Road San Luis Obispo CA

6 min drive from California Polytechnic State University

Stay at this spa hotel in San Luis Obispo. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...

9.2/10 Wonderful! (1,466 reviews)

Room was very clean, amazing, and affordable. The pool was bonkers!))

Reviewed on 11 May 2026

Inn at San Luis Obispo

1895 Monterey Street San Luis Obispo CA

16 min walk from California Polytechnic State University

Stay at this business-friendly motel in San Luis Obispo. Enjoy free Wi-Fi, free parking and a business centre. Our guests praise the helpful staff and the clean ...

7.6/10 Good! (1,014 reviews)

Good area to stay at. The hotel sheets were dirty, the curtain was torn and was coming off the wall. Besides that a good hotel if you need a room!

Reviewed on 10 May 2026

See all 403 properties in San Luis Obispo Wine Country

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.