The best area to stay in Villanova is generally along Lancaster Avenue (US Route 30), which serves as the main thoroughfare through the area.This stretch of Villanova, often referred to as the "Main Line," is characterised by its tree-lined streets, large homes, and the presence of Villanova University. It's a well-kept area with several high-quality hotels, local shops, and restaurants, providing a convenient and pleasant base for visitors.For visitors attending events or visiting students at Villanova University, staying directly on or just off Lancaster Avenue is the most convenient option. Many hotels in this area are within walking distance or a very short drive to the university campus, making it easy to get to lectures, sports events, or campus tours.Business travellers will also find Lancaster Avenue appealing due to its proximity to corporate offices and easy access to major roadways like I-476 and I-76, facilitating travel to Philadelphia or other business hubs in the region.