Photo by Karen Leone

Business Hotels & Resorts in South San Diego

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on South San Diego Business Hotels

Best South San Diego Business Hotels

Terrace/patio
Hampton Inn & Suites Imperial Beach San Diego

Hampton Inn & Suites Imperial Beach San Diego

2.5 star property
Imperial Beach
9.4 out of 10, Exceptional, (933)
"Great stay"
United States
Crystal
The price is NZ$249
includes taxes & fees
30 Nov - 1 Dec
Hampton Inn & Suites Imperial Beach San Diego
Meeting facility
Pier South Resort, Autograph Collection by Marriott

Pier South Resort, Autograph Collection by Marriott

4.0 star property
Imperial Beach
8.4 out of 10, Very good, (1000)
"Staff was amazing room with the view was just stunning "
United States
Alisa
The price is NZ$357
includes taxes & fees
23 Nov - 24 Nov
Pier South Resort, Autograph Collection by Marriott
Exterior
La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
Chula Vista
8.6 out of 10, Excellent, (1474)
"Great and friendly staff. Safe, clean and confortable rooms!"
United States
Eduardo E.
The price is NZ$202
includes taxes & fees
19 Nov - 20 Nov
La Quinta Inn by Wyndham San Diego Chula Vista
Exterior
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
Otay Mesa
8.0 out of 10, Very good, (1536)
"Good comfortable beds good breakfast "
United States
Andrey
The price is NZ$260
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Lobby
Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
Otay
7.8 out of 10, Good, (1522)
"Great place to stay, staff was fantastic "
United States
Pamela
The price is NZ$197
includes taxes & fees
25 Nov - 26 Nov
Best Western Chula Vista/Otay Valley Hotel
Lobby lounge
Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista

3.0 star property
Otay Ranch
9.8 out of 10, Exceptional, (1114)
"The room was spotless, the staff were all super nice, & the buffet breakfast was really good. "
United States
Sybil
The price is NZ$300
includes taxes & fees
24 Nov - 25 Nov
Ayres Hotel San Diego South - Chula Vista
Desk, laptop workspace, blackout curtains, iron/ironing board
Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa

2.5 star property
Otay Mesa
7.2 out of 10, Good, (1001)
"Clean, friendly staff and yummy breakfast :)"
United States
Iliana
The price is NZ$192
includes taxes & fees
19 Nov - 20 Nov
Quality Suites San Diego Otay Mesa
View from room
The Rambler

The Rambler

3.0 star property
Chula Vista
9.2 out of 10, Wonderful, (1990)
"Nice rooms, nice staff"
United States
Andrew
The price is NZ$179
includes taxes & fees
20 Nov - 21 Nov
The Rambler
Lobby
Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South

2.5 star property
Chula Vista
8.2 out of 10, Very good, (1198)
"Perfect family hotel "
United States
Lucia
The price is NZ$195
includes taxes & fees
7 Dec - 8 Dec
Comfort Inn Chula Vista San Diego South
Desk, blackout curtains, iron/ironing board, free WiFi
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
San Ysidro
7.8 out of 10, Good, (1354)
"Excelente hotel "
Mexico
Adrian Andrés
The price is NZ$122
includes taxes & fees
23 Nov - 24 Nov
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top South San Diego Hotel Reviews

Comfort Inn Sea World Area

Comfort Inn Sea World Area

10/10 Excellent
"Clean room, good amenities a great location for the airport"
Romina 1-night trip
Posted 2 days ago
Comfort Inn Sea World Area

Explore a world of travel with Expedia

Frequently asked questions

How much do business-friendly hotels in South San Diego cost?
Expect to pay between and per night for business-friendly hotels in South San Diego. Top deals on stays that cater to corporate travellers are just a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in South San Diego?
Pick from business-friendly hotels in South San Diego. Wherever work is taking you, Expedia can help you secure the ideal space with the amenities you need.
What are the top business-friendly motels in South San Diego?
Comfortable and cost-effective, motels are an ideal choice for your next South San Diego business trip. If a work event is taking you to Chula Vista, check in to Crown City Inn. It's around 10 kilometres northwest of downtown and includes amenities such as pool sun loungers and a swimming pool. The Rambler Motel also appeals to business travellers. It offers a swimming pool and a memory foam mattress and is located about 2 kilometres west of the centre of Chula Vista.Searching for some cool things to do during your downtime in Chula Vista? North Island Credit Union Amphitheatre and Len Moore Skate Park are among the excellent attractions you shouldn't miss.
What is there to do in South San Diego near my business-friendly hotel?
South San Diego offers so much to do and see, it can be challenging to decide where to start. If you're spending a night or two in Chula Vista, North Island Credit Union Amphitheatre is a much-loved attraction with travellers and locals alike.