Photo by Karen Leone
Business Hotels & Resorts in South San Diego from NZ$147
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on South San Diego Business Hotels
Our top choices for South San Diego business-friendly hotels
Hampton Inn & Suites Imperial Beach San Diego
Hampton Inn & Suites Imperial Beach San DiegoImperial Beach
9.4 out of 10, Exceptional, (1,009 reviews)
"Everything was great!"
Michelle
The price is NZ$281
includes taxes & fees
3 May - 4 May
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, Very good, (1,684 reviews)
"Great breakfast!"
Susan
The price is NZ$224
includes taxes & fees
3 May - 4 May
8.4 out of 10, Very good, (1,011 reviews)
"Great location, near shops, restaurants and beaches. "
Miguelina
The price is NZ$150
includes taxes & fees
12 Apr - 13 Apr
Pier South Resort, Autograph Collection by Marriott
Pier South Resort, Autograph Collection by MarriottImperial Beach
8.4 out of 10, Very good, (1,003 reviews)
"Just wished I didn’t have to pay for parking, but I do understand it is on the water and it is limited space to park not a complaint. Just wish I didn’t have to pay for parking though."
JOHN
The price is NZ$434
includes taxes & fees
10 May - 11 May
8.0 out of 10, Very good, (1,677 reviews)
"Very satisfied with stay, would recommend. "
Roberto
The price is NZ$207
includes taxes & fees
26 Apr - 27 Apr
8.4 out of 10, Very good, (278 reviews)
"Clean rooms, beautiful property, nice pools, great service."
Karen Lynn
The price is NZ$693
includes taxes & fees
10 May - 11 May
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Studio 6 Suites San Ysidro, CA -San Diego South BaySan Ysidro
8.0 out of 10, Very good, (1,583 reviews)
"Good location"
Joshua
The price is NZ$147
includes taxes & fees
12 Apr - 13 Apr
7.0 out of 10, Good, (1,005 reviews)
"Great staff.. location close to the airport!"
Vivian
The price is NZ$193
includes taxes & fees
10 May - 11 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top South San Diego Hotel Reviews
Marriott Marquis San Diego Marina
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- Otay Hotels
- Hotels near Len Moore Skate Park
- Chula Vista Hotels
- San Ysidro Hotels
- Nestor Hotels
- Hotels near Brown Field Municipal
- Otay Mesa West Hotels
- Imperial Beach Hotels
- Hotels near Palm Ave Trolley Station
- Bonita Hotels
- Hotels near Sky Zone San Diego Indoor Trampoline Park
- Hotels near San Ysidro Border Crossing
- Apartments in Chula Vista
- B&B in Chula Vista
- Residences in Chula Vista
- Hostels in San Ysidro
- Cottages in National City
- Apartments in South Bay
- Guest Houses in South Bay
- Serviced Apartments in South Bay
- Holiday Homes in South Bay
- Villas in South Bay
- Cottages in South Bay
- Holiday Homes in Imperial Beach
- Apartments in Imperial Beach
- Spa Hotels in San Diego
- Historic Hotels in San Diego
- Beach Hotels in San Diego
- Golf Hotels in San Diego
- Hotels with Parking in San Diego
- Boutique Hotels in San Diego
- Lgbt Welcoming Hotels in San Diego
- Ski Hotels in San Diego
- Family Hotels in Coronado
- Beach Hotels in Coronado
- Boutique Hotels in Downtown San Diego
- Luxury Hotels in Gaslamp Quarter
- Cheap Hotels in Gaslamp Quarter
- Boutique Hotels in South Bay
- Cheap Hotels in Otay Mesa
- Family Hotels in South San Diego
- Romantic Hotels in South San Diego
- Beach Hotels in South San Diego
- Luxury Hotels in Asian Pacific Thematic Historic District
- Cheap Hotels in San Diego County
- Casino Hotels in San Diego County
- Family Hotels in San Diego County
- All Inclusive Hotels in San Diego County
- Cheap Hotels in San Diego Coast
- Beach Hotels in San Diego Coast
- Hotels with Pool in San Diego Coast
- Winery Hotels in San Diego Coast
- All Inclusive Hotels in San Diego Coast
- Family Hotels in San Diego Coast
- Lgbt Welcoming Hotels in East Village
- Best Western Hotels in San Ysidro
- Flights from Las Vegas (LAS) to San Diego (SDM)
- Flights from Sydney (SYD) to San Diego (SDM)
- Flights from Los Angeles (LAX) to San Diego (SDM)
- Flights from San Francisco (SFO) to San Diego (SDM)
- Flights from Hong Kong (HKG) to San Diego (SDM)
- Flights from Long Beach (LGB) to San Diego (SDM)
- Flights from Henderson (HSH) to San Diego (SDM)
- Flights from Houston (IAH) to San Diego (SDM)
- Flights from Hartford (BDL) to San Diego (SDM)
- Flights from Boston (BOS) to San Diego (SDM)
- Flights from Denver (DEN) to San Diego (SDM)
- Flights from Orange County (SNA) to San Diego (SDM)
- Flights to San Ysidro
- Flights to Chula Vista
- Flights from Brown Field Municipal
- Visit Otay Mesa
- Visit Chula Vista
- Visit Eastlake Greens
- Visit Otay Mesa West
- Visit Bonita
- Visit Rancho del Rey
- Visit Otay
- San Ysidro Border Crossing
- Silver Strand State Beach
- Sharp Chula Vista Medical Center
- Chula Vista Center
- North Island Credit Union Amphitheatre
- Kaiser Permanente Otay Mesa Medical Offices
- Atlantis Laser Tag
- Las Americas Premium Outlets