Photo by Karen Leone

Business Hotels & Resorts in South San Diego from NZ$136

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on South San Diego Business Hotels

This weekend
Next weekend

Our top choices for South San Diego business-friendly hotels

Hampton Inn & Suites Imperial Beach San Diego

Hampton Inn & Suites Imperial Beach San Diego
2.5 star property
Imperial Beach
9.4 out of 10, Exceptional, (968)
"It’s always a great place to stay. The staff are so nice and friendly, rooms are very nice."
United States
Carolyn
The price is NZ$283
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn & Suites Imperial Beach San Diego

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very good, (1578)
"Great place to stay. Really clean and helpful staff "
United States
Zulma
The price is NZ$235
includes taxes & fees
11 Jan - 12 Jan
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Pier South Resort, Autograph Collection by Marriott

Pier South Resort, Autograph Collection by Marriott
4.0 star property
Imperial Beach
8.4 out of 10, Very good, (1005)
"Room was beautiful, everything about my stay was perfect."
United States
Victoria
The price is NZ$374
includes taxes & fees
8 Jan - 9 Jan
Pier South Resort, Autograph Collection by Marriott

La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
Chula Vista
8.6 out of 10, Excellent, (1504)
"Everything was great, staff , Room , clean , great place to stay "
United States
Luis
The price is NZ$177
includes taxes & fees
15 Jan - 16 Jan
La Quinta Inn by Wyndham San Diego Chula Vista

Hercor Hotel - Urban Boutique

Hercor Hotel - Urban Boutique
3.0 star property
Chula Vista
8.6 out of 10, Excellent, (1349)
"Clean room, friendly staff. Great breakfast. Many stores and food places near by. Highly recommended 👌 "
United States
Daniel
The price is NZ$161
includes taxes & fees
6 Jan - 7 Jan
Hercor Hotel - Urban Boutique

The Rambler

The Rambler
3.0 star property
Chula Vista
9.2 out of 10, Wonderful, (2025)
"Absolutely amazing stay will def be coming back!"
United States
Victor
The price is NZ$189
includes taxes & fees
6 Jan - 7 Jan
The Rambler

Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
Otay
7.8 out of 10, Good, (1568)
"Great relaxing stay "
United States
Gustavo
The price is NZ$193
includes taxes & fees
18 Jan - 19 Jan
Best Western Chula Vista/Otay Valley Hotel

Quality Inn San Diego South - Chula Vista

Quality Inn San Diego South - Chula Vista
2.5 star property
Chula Vista
7.8 out of 10, Good, (1003)
"Staff was great!"
United States
jennifer
The price is NZ$136
includes taxes & fees
11 Jan - 12 Jan
Quality Inn San Diego South - Chula Vista

Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
Chula Vista
8.2 out of 10, Very good, (1285)
"Great hotel"
United States
Rafael
The price is NZ$193
includes taxes & fees
18 Jan - 19 Jan
Comfort Inn Chula Vista San Diego South

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.2 out of 10, Good, (1010)
"Clean, convenient location "
United States
Mary
The price is NZ$194
includes taxes & fees
11 Jan - 12 Jan
Quality Suites San Diego Otay Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top South San Diego Hotel Reviews

Frequently asked questions

How much do business-friendly hotels in South San Diego cost?
Expect to pay between NZ$136 and NZ$374 per night for business-friendly hotels in South San Diego. Top deals on stays that cater to corporate travellers are just a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in South San Diego?
Pick from 24 business-friendly hotels in South San Diego. Wherever work is taking you, Expedia can help you secure the ideal space with the amenities you need.
What are the top business-friendly motels in South San Diego?
Comfortable and cost-effective, motels are an ideal choice for your next South San Diego business trip. If a work event is taking you to Chula Vista, check in to Crown City Inn. It's around 10 kilometres northwest of downtown and includes amenities such as pool sun loungers and a swimming pool. The Rambler Motel also appeals to business travellers. It offers a swimming pool and a memory foam mattress and is located about 2 kilometres west of the centre of Chula Vista.Searching for some cool things to do during your downtime in Chula Vista? North Island Credit Union Amphitheatre and Len Moore Skate Park are among the excellent attractions you shouldn't miss.
What is there to do in South San Diego near my business-friendly hotel?
South San Diego offers so much to do and see, it can be challenging to decide where to start. If you're spending a night or two in Chula Vista, North Island Credit Union Amphitheatre is a much-loved attraction with travellers and locals alike.

Explore a world of travel with Expedia