Mira Mesa Hotels, San Diego

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mira Mesa hotels

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
32.8 km from Mira Mesa
9.2 out of 10, Wonderful, (1650)
"Very nice getaway for the family "
United States
Richard
Sycuan Casino Resort

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
19.1 km from Mira Mesa
7.4 out of 10, Good, (4127)
"Get location to the airport, safe, great staff, & overall wonderful stay"
United States
Tyler
The price is NZ$168
includes taxes & fees
6 Jan - 7 Jan 2026
Wyndham Garden San Diego Near SeaWorld

Holiday Inn Carlsbad by IHG

Holiday Inn Carlsbad by IHG
3.0 star property
26.1 km from Mira Mesa
9.0 out of 10, Wonderful, (1003)
"Always a great place to stay we love here "
United States
Luis
The price is NZ$188
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Carlsbad by IHG

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 16.4 km from Mira Mesa
8.4 out of 10, Very good, (1317)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
United States
Haley
The price is NZ$363
includes taxes & fees
4 Jan - 5 Jan 2026
San Diego Mission Bay Resort

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
22 km from Mira Mesa
8.4 out of 10, Very good, (6013)
"Always an amazing stay"
United States
Jana
The price is NZ$303
includes taxes & fees
4 Jan - 5 Jan 2026
Wyndham San Diego Bayside

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
Old Town San Diego, 19.1 km from Mira Mesa
8.2 out of 10, Very good, (1918)
"Great stay "
United States
Vanessa
The price is NZ$181
includes taxes & fees
20 Jan - 21 Jan 2026
Comfort Inn San Diego Old Town

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 22.8 km from Mira Mesa
9.4 out of 10, Exceptional, (1001)
"Great location "
United States
Mohammad
The price is NZ$226
includes taxes & fees
6 Jan - 7 Jan 2026
Staypineapple, Hotel Z, Gaslamp San Diego

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
16.3 km from Mira Mesa
8.4 out of 10, Very good, (1441)
"The room was super quiet and clean. The staff was kind at check in and check out. We would definitely stay here again. "
United States
Janelle
The price is NZ$223
includes taxes & fees
3 Jan - 4 Jan 2026
DoubleTree by Hilton Hotel San Diego - Mission Valley

Hampton Inn Carlsbad-North San Diego County

Hampton Inn Carlsbad-North San Diego County
2.5 star property
26.3 km from Mira Mesa
9.2 out of 10, Wonderful, (1000)
"Clean room, good breakfast, friendly staff and common areas very clean. "
United States
Viridiana
The price is NZ$207
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn Carlsbad-North San Diego County

Leucadia Beach Inn

Leucadia Beach Inn
2.5 star property
22.9 km from Mira Mesa
9.4 out of 10, Exceptional, (1000)
"Friendly staff, nice barbecue 😋 "
United States
Gary
The price is NZ$169
includes taxes & fees
4 Jan - 5 Jan 2026
Leucadia Beach Inn

Lakehouse Resort

Lakehouse Resort
4.0 star property
24 km from Mira Mesa
9.2 out of 10, Wonderful, (1310)
"It was a great time for the family We were able to walk to Brickman's restaurant for their Winter Wonderland festivities. "
United States
Ryan
The price is NZ$239
includes taxes & fees
5 Jan - 6 Jan 2026
Lakehouse Resort

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
23.5 km from Mira Mesa
9.2 out of 10, Wonderful, (3234)
"Great stay and location!"
United States
Jason
The price is NZ$213
includes taxes & fees
4 Jan - 5 Jan 2026
Bay Club Hotel & Marina

Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach
2.5 star property
Pacific Beach, 14.3 km from Mira Mesa
8.8 out of 10, Excellent, (814)
"Good location, good basic breakfast, good parking, recommended. "
United States
Leyla
The price is NZ$204
includes taxes & fees
5 Jan - 6 Jan 2026
Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
17.7 km from Mira Mesa
8.8 out of 10, Excellent, (3581)
"Nice staff, clean rooms and the Waffle Spot!!!!"
United States
brent
Kings Inn San Diego

Best Western Carlsbad by the Sea

Best Western Carlsbad by the Sea
2.5 star property
26.5 km from Mira Mesa
8.0 out of 10, Very good, (1054)
"Friendly staff, free breakfast and clean rooms"
United States
Kristen
The price is NZ$163
includes taxes & fees
7 Jan - 8 Jan 2026
Best Western Carlsbad by the Sea

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
21.5 km from Mira Mesa
8.4 out of 10, Very good, (3176)
"The stay and staff were wonderful and very helpful.."
United States
Elsie
The price is NZ$309
includes taxes & fees
4 Jan - 5 Jan 2026
Sheraton San Diego Resort

West Inn & Suites

West Inn & Suites
3.5 star property
30.1 km from Mira Mesa
9.4 out of 10, Exceptional, (1080)
"Great place!"
United States
Adam
The price is NZ$289
includes taxes & fees
3 Jan - 4 Jan 2026
West Inn & Suites

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 9 km from Mira Mesa
8.4 out of 10, Very good, (1932)
"Nice hotel"
United States
Xiaoyang
The price is NZ$228
includes taxes & fees
6 Jan - 7 Jan 2026
DoubleTree by Hilton San Diego - Del Mar

Carlsbad By The Sea Hotel

Carlsbad By The Sea Hotel
3.0 star property
28.2 km from Mira Mesa
7.8 out of 10, Good, (1773)
"Very kind staff, comfortable room, and an amazing heated pool! It was an amazing place to stay :) "
United States
Haley
Carlsbad By The Sea Hotel

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
23.8 km from Mira Mesa
8.8 out of 10, Excellent, (1561)
"Staff was great, easy check in and great location"
United States
Alysa
The price is NZ$233
includes taxes & fees
14 Jan - 15 Jan 2026
Best Western Plus Island Palms Hotel & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Mira Mesa

Find the best Mira Mesa areas for the activities you enjoy most. Learn more about Mira Mesa
Learn more about Mira Mesa

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Sunset Cliffs Natural Park.

Top Mira Mesa Hotel Reviews

Frequently asked questions

What's it like in Mira Mesa?
Mira Mesa is a neighbourhood that travellers like for its restaurants and bars. Consider a visit to Regal Edwards Mira Mesa as part of your Mira Mesa travel plans.
How many hotels should I expect to find in the Mira Mesa area?
Expedia has 44 hotels and other accommodation options in Mira Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Mira Mesa, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get the best deals in Mira Mesa.
What is there to do in this San Diego neighbourhood?
Regal Edwards Mira Mesa is an attraction you might want to check out while you're in Mira Mesa. While you're out sightseeing in San Diego, make sure that you visit other sights such as Rancho Penasquitos Tennis Center or Lake Miramar.

Explore a world of travel with Expedia