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Middletown Hotels, San Diego

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Our top choices for Middletown hotels

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (108)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay, 6.8 km from Middletown
8.4 out of 10, Very good, (1589)
"Totally Recommend! Rooms are really clean and comfortable, the staff are great as well. "
United States
Fernando
The price is NZ$357
includes taxes & fees
10 Jan - 11 Jan 2026
Hyatt Regency Mission Bay Spa and Marina

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
2.3 km from Middletown
8.4 out of 10, Very good, (6013)
"Always an amazing stay"
United States
Jana
The price is NZ$303
includes taxes & fees
4 Jan - 5 Jan 2026
Wyndham San Diego Bayside

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
4.1 km from Middletown
7.4 out of 10, Good, (4128)
"Get location to the airport, safe, great staff, & overall wonderful stay"
United States
Tyler
The price is NZ$168
includes taxes & fees
6 Jan - 7 Jan 2026
Wyndham Garden San Diego Near SeaWorld

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 3.6 km from Middletown
9.4 out of 10, Exceptional, (1001)
"Great location "
United States
Mohammad
The price is NZ$226
includes taxes & fees
6 Jan - 7 Jan 2026
Staypineapple, Hotel Z, Gaslamp San Diego

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 5.4 km from Middletown
8.4 out of 10, Very good, (1317)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
United States
Haley
The price is NZ$363
includes taxes & fees
4 Jan - 5 Jan 2026
San Diego Mission Bay Resort

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 3.4 km from Middletown
9.0 out of 10, Wonderful, (2880)
"Lovely hotel with friendly staff."
United States
Lynnea
The price is NZ$446
includes taxes & fees
1 Jan - 2 Jan 2026
Manchester Grand Hyatt San Diego

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
3.6 km from Middletown
8.4 out of 10, Very good, (1442)
"The room was super quiet and clean. The staff was kind at check in and check out. We would definitely stay here again. "
United States
Janelle
The price is NZ$223
includes taxes & fees
3 Jan - 4 Jan 2026
DoubleTree by Hilton Hotel San Diego - Mission Valley

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
Old Town San Diego, 2.1 km from Middletown
8.2 out of 10, Very good, (1918)
"Great stay "
United States
Vanessa
The price is NZ$181
includes taxes & fees
20 Jan - 21 Jan 2026
Comfort Inn San Diego Old Town

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
5.4 km from Middletown
9.2 out of 10, Wonderful, (3234)
"Great stay and location!"
United States
Jason
The price is NZ$213
includes taxes & fees
4 Jan - 5 Jan 2026
Bay Club Hotel & Marina

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
2.2 km from Middletown
8.8 out of 10, Excellent, (833)
"would stay again and recommend "
United States
Brendi
The price is NZ$221
includes taxes & fees
4 Jan - 5 Jan 2026
The DEXTRO Little Italy, BW Premier Collection

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 3.7 km from Middletown
9.0 out of 10, Wonderful, (1239)
"Clean, courteous staff, good location. "
United States
Carla
The price is NZ$274
includes taxes & fees
2 Jan - 3 Jan 2026
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Marina District, 4.2 km from Middletown
8.6 out of 10, Excellent, (1892)
"Enjoyed my stay"
United States
Brandon
The price is NZ$327
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton San Diego Bayfront

Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach
2.5 star property
Pacific Beach, 7.8 km from Middletown
8.8 out of 10, Excellent, (814)
"Good location, good basic breakfast, good parking, recommended. "
United States
Leyla
The price is NZ$204
includes taxes & fees
5 Jan - 6 Jan 2026
Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 3.8 km from Middletown
9.0 out of 10, Wonderful, (3178)
"Beautiful hotel"
United States
Jordan M.
Hard Rock Hotel San Diego

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
5.7 km from Middletown
8.8 out of 10, Excellent, (1562)
"Staff was great, easy check in and great location"
United States
Alysa
The price is NZ$233
includes taxes & fees
14 Jan - 15 Jan 2026
Best Western Plus Island Palms Hotel & Marina

Hotel Palmeras Chula Vista

Hotel Palmeras Chula Vista
2.0 star property
13.5 km from Middletown
7.2 out of 10, Good, (2024)
"Great stay"
United States
Bobby
The price is NZ$119
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Palmeras Chula Vista

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 22.6 km from Middletown
8.4 out of 10, Very good, (1932)
"Nice hotel"
United States
Xiaoyang
The price is NZ$228
includes taxes & fees
6 Jan - 7 Jan 2026
DoubleTree by Hilton San Diego - Del Mar

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
2.5 km from Middletown
8.4 out of 10, Very good, (3177)
"The stay and staff were wonderful and very helpful.."
United States
Elsie
The price is NZ$309
includes taxes & fees
4 Jan - 5 Jan 2026
Sheraton San Diego Resort

Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown
2.5 star property
2.1 km from Middletown
8.2 out of 10, Very good, (2319)
"Nice and convenient place to stay!"
United States
Esperanza
The price is NZ$226
includes taxes & fees
14 Jan - 15 Jan 2026
Hampton Inn San Diego-Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Middletown

Find the best Middletown areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Sunset Cliffs Natural Park.

Top Middletown Hotel Reviews

Frequently asked questions

What's it like in Middletown?
Middletown is a neighbourhood that travellers like for its live music, bars and theatres.
How many hotels can I expect to find in the Middletown area?
Expedia has 91 hotels and other accommodation options in Middletown to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Middletown, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to view top deals in Middletown.
What are the top things to see and do in Middletown?
Favourite places to visit in the surrounding area include San Diego Zoo, Hotel Circle and Port of San Diego. While you're out sightseeing, Petco Park and Marston House are a couple of additional sights to visit in San Diego.
How can I get around Middletown and the greater San Diego area?
Ready to get out and explore the city? Middletown Station is the closest metro station.

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