Photo by Karla Hernandez
Middletown Hotels, San Diego
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Middletown hotels
9.6 out of 10, Exceptional, (108)
"would definitely go back and stay there again "
Kounwick
Hyatt Regency Mission Bay Spa and Marina
Hyatt Regency Mission Bay Spa and MarinaMission Bay, 6.8 km from Middletown
8.4 out of 10, Very good, (1589)
"Totally Recommend! Rooms are really clean and comfortable, the staff are great as well. "
Fernando
The price is NZ$357
includes taxes & fees
10 Jan - 11 Jan 2026
8.4 out of 10, Very good, (6013)
"Always an amazing stay"
Jana
The price is NZ$303
includes taxes & fees
4 Jan - 5 Jan 2026
7.4 out of 10, Good, (4128)
"Get location to the airport, safe, great staff, & overall wonderful stay"
Tyler
The price is NZ$168
includes taxes & fees
6 Jan - 7 Jan 2026
Staypineapple, Hotel Z, Gaslamp San Diego
Staypineapple, Hotel Z, Gaslamp San DiegoGaslamp Quarter, 3.6 km from Middletown
9.4 out of 10, Exceptional, (1001)
"Great location "
Mohammad
The price is NZ$226
includes taxes & fees
6 Jan - 7 Jan 2026
8.4 out of 10, Very good, (1317)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
Haley
The price is NZ$363
includes taxes & fees
4 Jan - 5 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our guide on where to stay in Middletown
Find the best Middletown areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Gaslamp Quarter
The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Ocean Beach
Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Sunset Cliffs Natural Park.
Top Middletown Hotel Reviews
DoubleTree by Hilton Hotel San Diego - Mission Valley
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- Spa Hotels in San Diego
- Beach Hotels in Hillcrest
- All Inclusive Hotels in Downtown San Diego
- Wyndham Extra Holidays Hotels in San Diego
- Little Italy Hotels
- North Park Hotels
- Hotels near San Diego Zoo
- Marina District Hotels
- Hotels near Hotel Circle
- Hillcrest Hotels
- South Park Hotels
- Mission Valley Hotels
- East Village Hotels
- Hotels near Seaport Village
- Downtown San Diego Hotels
- San Diego Hotels
- Mission Hills Hotels
- Hotels near Maritime Museum of San Diego
- Bankers Hill Hotels
- Liberty Station Hotels
- Gaslamp Quarter Hotels
- Cortez Hill Hotels
- Hotels near Humphreys Concerts by the Bay
- Hotels near Balboa Park Carousel
- Hotels near San Diego Intl.
- Midway-Pacific Highway Hotels
- San Diego County Hotels
- Hotels near Navy Pier
- Hotels near Centennial Park
- Linda Vista Hotels
- Hotels near Balboa Park
- Hotels near B Street Cruise Ship Terminal
- Old Town San Diego Hotels
- Virgin Atlantic London (LHR) to San Diego (SAN) flights
- American Airlines Vail (EGE) to San Diego (SAN) flights
- Alaska Airlines San Francisco (SFO) to San Diego (SAN) flights
- Delta St. Louis (STL) to San Diego (SAN) flights
- Air Canada Rio de Janeiro (GIG) to San Diego (SAN) flights
- Flights from Columbus (LCK) to San Diego (SAN)
- Flights from Calgary (YYC) to San Diego (SAN)
- Flights from Santa Cruz (STU) to San Diego (SAN)
- Flights from Jacksonville (JAX) to San Diego (SAN)
- Flights from Las Vegas (LAS) to San Diego (SAN)
- Flights from Eugene (EUG) to San Diego (SAN)
- Flights from Brisbane (BNE) to San Diego (SAN)
- Flights from San Francisco (SFO) to San Diego (SAN)
- Flights from Coffman Cove (KCC) to San Diego (SAN)
- Flights from Sydney (SYD) to San Diego (SAN)
- Flights from Charlotte (CLT) to San Diego (SAN)
- Flights from Burbank (BUR) to San Diego (SAN)
- Flights from Redding (RDD) to San Diego (SAN)
- Flights from San Juan (SJU) to San Diego (SAN)
- Flights from Greenville (PGV) to San Diego (SAN)
- Flights from Raleigh (RDU) to San Diego (SAN)
- Flights from León (BJX) to San Diego (SAN)
- Flights from Silver City (SVC) to San Diego (SAN)
- Flights from Wilmington (ILM) to San Diego (SAN)
- Flights from Providence (PVD) to San Diego (SAN)
- Flights from Dunedin (DUD) to San Diego (SAN)
- Flights from Sacramento (SAC) to San Diego (SAN)
- Flights from Brownsville (BRO) to San Diego (SAN)
- Flights from Milan (LIN) to San Diego (SAN)
- Flights from Buenaventura (BUN) to San Diego (SAN)
- Flights from Palm Springs (PSP) to San Diego (SAN)
- Flights from Boulder (WBU) to San Diego (SAN)
- Flights from Washington (DCA) to San Diego (SAN)
- Flights from Taipei (TPE) to San Diego (SAN)
- Flights from Pontianak (PNK) to San Diego (SAN)
- Flights from Gamarra (GRA) to San Diego (SAN)
- Flights from Boston (BOS) to San Diego (SAN)
- Flights from Amsterdam (AMS) to San Diego (SAN)
- Flights from Kansas City (MCI) to San Diego (SAN)
- Flights from Nadi (NAN) to San Diego (SAN)
- Flights from Lexington (LEX) to San Diego (SAN)
- Flights from Auckland (AKL) to San Diego (SAN)
- Flights from Niamey (NIM) to San Diego (SAN)
- Flights from Nashville (BNA) to San Diego (SAN)
- Flights from Cape Town (CPT) to San Diego (SAN)
- Flights from Querétaro (QRO) to San Diego (SAN)
- Flights from New York (LGA) to San Diego (SAN)
- Flights from Carson City (CSN) to San Diego (SAN)
- Flights from Panama City (ECP) to San Diego (SAN)
- Flights from Vancouver (YVR) to San Diego (SAN)
- Flights from Villahermosa (VSA) to San Diego (SAN)
- Flights from Mexico City (MEX) to San Diego (SAN)
- Flights from Tortola (EIS) to San Diego (SAN)
- Flights from Hanoi (HAN) to San Diego (SAN)
- Flights from Lancaster (LNS) to San Diego (SAN)
- Flights from Niagara Falls (IAG) to San Diego (SAN)
- Flights from Houston (IAH) to San Diego (SAN)
- Flights from Santiago (SCL) to San Diego (SAN)
- Flights from Anchorage (ANC) to San Diego (SAN)
- Flights from Lihue (LIH) to San Diego (SAN)