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Our top choices for La Mesa hotels

Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego
2.5 star property
La Mesa
8.2 out of 10, Very good, (1001)
"Clean room, great breakfast, pleasant staff. It was comfortable. "
United States
Vonda
The price is NZ$184
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus La Mesa San Diego

Heritage Inn La Mesa

Heritage Inn La Mesa
2.0 star property
La Mesa
7.0 out of 10, Good, (1198)
"room was clean and staff very friendly"
United States
Charles
The price is NZ$121
includes taxes & fees
14 Dec - 15 Dec
Heritage Inn La Mesa

Holiday Inn Express La Mesa Near SDSU by IHG

Holiday Inn Express La Mesa Near SDSU by IHG
3.0 star property
La Mesa
8.2 out of 10, Very good, (450)
"Great Stay"
United States
Jazmin
The price is NZ$257
includes taxes & fees
18 Dec - 19 Dec
Holiday Inn Express La Mesa Near SDSU by IHG

Motel 6 La Mesa, CA

Motel 6 La Mesa, CA
2.0 star property
La Mesa
7.2 out of 10, Good, (1001)
"Easy parking, clean, nice staff, safe"
United States
Martha
The price is NZ$170
includes taxes & fees
24 Dec - 25 Dec
Motel 6 La Mesa, CA

Motel 6 La Mesa, CA - San Diego

Motel 6 La Mesa, CA - San Diego
2.0 star property
La Mesa
7.4 out of 10, Good, (976)
"Best Motel 6 I’ve ever been too! Clean marbel showers and comfortable beds!"
United States
Izaiah
The price is NZ$164
includes taxes & fees
14 Dec - 15 Dec
Motel 6 La Mesa, CA - San Diego

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
National City
9.2 out of 10, Wonderful, (3506)
"Great friendly staff "
United States
mohammed
The price is NZ$221
includes taxes & fees
16 Dec - 17 Dec
Best Western Plus Marina Gateway Hotel

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (3143)
"Great stay"
United States
Laurence
The price is NZ$418
includes taxes & fees
24 Dec - 25 Dec
Hard Rock Hotel San Diego

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
Downtown San Diego
8.4 out of 10, Very good, (6045)
"Always an amazing stay"
United States
Jana
The price is NZ$319
includes taxes & fees
24 Dec - 25 Dec
Wyndham San Diego Bayside

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1229)
"Very nice clean room and amenities and staff was pleasant and we love the location. "
United States
Arnold
The price is NZ$273
includes taxes & fees
24 Dec - 25 Dec
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Ayres Lodge Alpine

Ayres Lodge Alpine
3.0 star property
Alpine
9.2 out of 10, Wonderful, (1004)
"Great hotel."
United States
TOMLINSON,
The price is NZ$204
includes taxes & fees
21 Dec - 22 Dec
Ayres Lodge Alpine

The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter
3.5 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2696)
"Clean facilities and friendly staff!"
United States
EMMA
The Horton Grand, Downtown/Gaslamp Quarter

Viejas Casino & Willows Hotel

Viejas Casino & Willows Hotel
4.0 star property
Alpine
9.2 out of 10, Wonderful, (1003)
"Nice location and the ambient was the best."
United States
ivan
The price is NZ$266
includes taxes & fees
15 Dec - 16 Dec
Viejas Casino & Willows Hotel

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
Downtown San Diego
8.6 out of 10, Excellent, (1445)
"So clean, Very Nice staff, convenient location ! "
United States
Cindy
The Bristol Hotel San Diego

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1012)
"Yes everything was great I will stay there again."
United States
Sergio
The price is NZ$233
includes taxes & fees
24 Dec - 25 Dec
Gaslamp Plaza Suites

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
Point Loma
9.2 out of 10, Wonderful, (3177)
"Great stay and location!"
United States
Jason
The price is NZ$240
includes taxes & fees
6 Jan - 7 Jan 2026
Bay Club Hotel & Marina

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2941)
"Everything was super comfortable and the room was surprisingly affordable for the amenities you get. We will definitely stay there again if we go to San Diego."
United States
Eric
The price is NZ$303
includes taxes & fees
14 Dec - 15 Dec
Legacy Resort Hotel & Spa

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1000)
"Great location "
United States
Mohammad
The price is NZ$263
includes taxes & fees
30 Dec - 31 Dec
Staypineapple, Hotel Z, Gaslamp San Diego

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay
9.0 out of 10, Wonderful, (3912)
"The room was spotless the bed was so comfy the Amenities were great!! The food at the restaurant very delish"
United States
Emily
The price is NZ$309
includes taxes & fees
4 Jan - 5 Jan 2026
The Dana on Mission Bay

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

La Quinta Inn & Suites by Wyndham San Diego Mission Bay
3.0 star property
Pacific Beach
8.0 out of 10, Very good, (1424)
"Friendly staff, clean room"
United States
Janice
The price is NZ$189
includes taxes & fees
14 Dec - 15 Dec
La Quinta Inn & Suites by Wyndham San Diego Mission Bay

The Sofia Hotel

The Sofia Hotel
3.5 star property
Downtown San Diego
8.4 out of 10, Very good, (1654)
"Great location and history to the hotel "
United States
Stephanie
The Sofia Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in La Mesa

Find the best La Mesa areas for the activities you enjoy most. Learn more about La Mesa
Learn more about La Mesa

Mount Helix

If you're looking for some top things to see and do in Mount Helix and surrounding area, you can visit Mount Helix Park and The Magnolia.

Windsor Hills

While there might not be top attractions in Windsor Hills, you can explore the larger area and discover places like Cal Coast Credit Union Open Air Theater and Viejas Arena.

Stay near popular La Mesa attractions

Learn more about La Mesa

Nestled between rolling hills, this charming suburb offers hiking trails through Mission Trails Park and Lake Murray's scenic waterfront paths. Visit the vibrant farmers market on Fridays, then explore the antique shops and local breweries along La Mesa Boulevard's historic district.

View from Mount Helix, in La Mesa, near San Diego, California

Top La Mesa Hotel Reviews

More cheap accommodation in La Mesa

Frequently asked questions

What's the best place for a stay in La Mesa?
Best Western Plus La Mesa San Diego is a favourite property for Expedia customers. This hotel offers free breakfast and an outdoor pool. Reviews from our site also recommend Holiday Inn Express La Mesa Near SDSU by IHG and Motel 6 La Mesa, CA as top choices for your stay. See all available top hotels, or vacation rentals in La Mesa.
What are some of the best holiday rentals that La Mesa has to offer?
Spanish Casita in the Village of La Jolla - Walk to Everything: This holiday home rental outside of La Mesa is located near the beach, and has a balcony, a selection of games and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a fridge, a microwave and a coffee maker. See all vacation rentals in La Mesa.
If I need to cancel my hotel reservation in La Mesa, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.
What's the best family accommodation in La Mesa?
Holiday Inn Express La Mesa Near SDSU by IHG is a hotel with an outdoor pool and free breakfast, and it's a top choice on Expedia for families. Also, children of all ages will enjoy a visit to Computer Museum of America. Find more child-friendly accommodations in La Mesa.
What is the favourite LGBTQ-friendly accommodation in La Mesa?
Holiday Inn Express La Mesa Near SDSU by IHG is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Heritage Inn La Mesa is another good option for your trip. See all available hotels listed as LGBTQ-friendly in La Mesa.
What's the best dog-friendly place to stay in La Mesa?
Holiday Inn Express La Mesa Near SDSU by IHG is a top hotel for people travelling with their pets, and offers an outdoor pool and free WiFi for its human guests. Two other good options for you and your pet include Motel 6 La Mesa, CA - San Diego and Motel 6 La Mesa, CA. See more pet-friendly hotel accommodations in La Mesa.
What are some accommodation options with pools in La Mesa?
Holiday Inn Express La Mesa Near SDSU by IHG is a top hotel with a pool, free buffet breakfast and free WiFi. View all hotels with pools in La Mesa.
What is staying in La Mesa like?
Families will find child-friendly activities in La Mesa, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its shopping, zoo and entertainment. Around the area, top sights include San Diego Zoo, Petco Park and Port of San Diego. In La Mesa, there are 155 hotels and other accommodation options to choose from. Find out more about La Mesa.
What is there to see in La Mesa?
A couple of favourite places to visit are Mount Helix Park and Computer Museum of America. You'll also find San Diego Zoo and Petco Park in the area. Take a look at what more there is to see and do in Expedia's La Mesa guide.
How should I get around La Mesa?
You can take advantage of metro transport at La Mesa Boulevard Station, Spring St Trolley Station and 70th St. Trolley Station. If you want to venture out around the area, you may want a rental car in La Mesa for your journey.
What's the seasonal weather in La Mesa?
The hottest months are usually August and September, with an average temperature of 22°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for La Mesa is 308 mm.

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