Santo Domingo Hotels, Mexico City

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Our top choices for Santo Domingo hotels

Hotel Stanza

Hotel Stanza
3.5 star property
Roma Norte, 10.1 km from Santo Domingo
9.0 out of 10, Wonderful, (1,001 reviews)
"Hotel location was perfect for all the things that we wanted to do! "
United States
Eduardo
Hotel Stanza

Gran Hotel Ciudad de Mexico Zocalo View

Gran Hotel Ciudad de Mexico Zocalo View
4.5 star property
Historic Center, 11.9 km from Santo Domingo
9.8 out of 10, Exceptional, (1,128 reviews)
"Great location; beautiful historical hotel; great staff and awesome views "
United States
Raquel
The price is NZ$471
includes taxes & fees
3 Mar - 4 Mar
Gran Hotel Ciudad de Mexico Zocalo View

Hotel Casa González

Hotel Casa González
3.0 star property
Colonia Cuauhtémoc, 11.3 km from Santo Domingo
9.0 out of 10, Wonderful, (398 reviews)
"Lovely local place, very clean and excellent location. Great value for cost."
United States
Mia
The price is NZ$141
includes taxes & fees
16 Feb - 17 Feb
Hotel Casa González

Casa Decu

Casa Decu
4.0 star property
Hipódromo, 8.9 km from Santo Domingo
9.4 out of 10, Exceptional, (848 reviews)
"Great location if youre looking to explore Condesa"
United States
Caroline
Casa Decu

Suites Mine

Suites Mine
3.0 star property
Colonia Cuauhtémoc, 11.3 km from Santo Domingo
9.6 out of 10, Exceptional, (539 reviews)
"Excelente "
Mexico
Francisco
Suites Mine

Emporio Reforma

Emporio Reforma
3.5 star property
Juárez, 11.5 km from Santo Domingo
8.8 out of 10, Excellent, (1,003 reviews)
"Staff was amazing all around. Very friendly, amazing location, walked to the big park to the "
United States
Edward
The price is NZ$227
includes taxes & fees
3 Feb - 4 Feb
Emporio Reforma

Geneve Ciudad de México

Geneve Ciudad de México
4.0 star property
Zona Rosa, 10.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1,797 reviews)
"Room was clean and hotel located in a great spot."
Canada
Andreas
The price is NZ$226
includes taxes & fees
1 Mar - 2 Mar
Geneve Ciudad de México

Amberes 64, an Ascend Collection Hotel

Amberes 64, an Ascend Collection Hotel
3.0 star property
Zona Rosa, 10.7 km from Santo Domingo
9.4 out of 10, Exceptional, (557 reviews)
"Friendly staff and great location. "
United States
Sonia
The price is NZ$286
includes taxes & fees
4 Feb - 5 Feb
Amberes 64, an Ascend Collection Hotel

Hotel Casa Blanca

Hotel Casa Blanca
3.5 star property
11.9 km from Santo Domingo
9.0 out of 10, Wonderful, (1,206 reviews)
"Breakfast menu was excellent, so I recommend to pay extra for this. The staff at the restaurant are amazing. "
United States
Fernando Sanchez
The price is NZ$183
includes taxes & fees
10 Feb - 11 Feb
Hotel Casa Blanca

Historico Central Hotel

Historico Central Hotel
4.0 star property
Historic Center, 12 km from Santo Domingo
9.8 out of 10, Exceptional, (2,400 reviews)
"We loved everything from this hotel! The location, cleanliness, welcome gift, amenities, free breakfast, staff, and 24-hour food and drink service. I’d definitely stay here again."
United States
Jolene
The price is NZ$286
includes taxes & fees
24 Feb - 25 Feb
Historico Central Hotel

LaiLa Hotel CDMX

LaiLa Hotel CDMX
4.0 star property
Colonia Cuauhtémoc, 11 km from Santo Domingo
9.0 out of 10, Wonderful, (1,486 reviews)
"Excelente hotel "
Mexico
Cristian
LaiLa Hotel CDMX

Fiesta Inn Centro Historico

Fiesta Inn Centro Historico
3.5 star property
Reforma, 12 km from Santo Domingo
9.0 out of 10, Wonderful, (1,074 reviews)
"Nice location, specious and cean rooms. Friendly and efficient staff. "
United States
Enrique
The price is NZ$209
includes taxes & fees
22 Feb - 23 Feb
Fiesta Inn Centro Historico

Reforma Capital Inn

Reforma Capital Inn
2.0 star property
Juárez, 10.8 km from Santo Domingo
8.6 out of 10, Excellent, (311 reviews)
"Clean room nice staff "
United States
Gilberto
The price is NZ$162
includes taxes & fees
9 Feb - 10 Feb
Reforma Capital Inn

KALI Centro Mexico City

KALI Centro Mexico City
3.0 star property
Downtown Mexico City, 11.2 km from Santo Domingo
9.4 out of 10, Exceptional, (379 reviews)
"Great stay. Need a better brunch. "
Canada
Cedrik
KALI Centro Mexico City

Hotel Block Suites

Hotel Block Suites
3.0 star property
Roma Norte, 10.5 km from Santo Domingo
8.6 out of 10, Excellent, (1,000 reviews)
"good place to stay for the price all the amenities are perfect"
United States
Andrea Vianney
The price is NZ$184
includes taxes & fees
3 Feb - 4 Feb
Hotel Block Suites

KALI Escandon Mexico City

KALI Escandon Mexico City
3.5 star property
8.2 km from Santo Domingo
9.2 out of 10, Wonderful, (1,002 reviews)
"Everything, the staff is excellent and very helpful, rooms are well maintained, very quiet neighborhood "
Canada
Andre
KALI Escandon Mexico City

Colony Residences & Suites

Colony Residences & Suites
2.5 star property
Roma Norte, 9.9 km from Santo Domingo
9.2 out of 10, Wonderful, (171 reviews)
"Nice location!"
United States
Rancer
The price is NZ$170
includes taxes & fees
9 Feb - 10 Feb
Colony Residences & Suites

HS HOTSSON Long Stay CDMX Condesa Sur

HS HOTSSON Long Stay CDMX Condesa Sur
3.5 star property
8.8 km from Santo Domingo
9.2 out of 10, Wonderful, (849 reviews)
"The service is nice and the hotel is very clean"
Canada
Fangyun
The price is NZ$202
includes taxes & fees
15 Feb - 16 Feb
HS HOTSSON Long Stay CDMX Condesa Sur

Zocalo Central & Rooftop Mexico City

Zocalo Central & Rooftop Mexico City
4.0 star property
Historic Center, 12.1 km from Santo Domingo
9.8 out of 10, Exceptional, (2,694 reviews)
"Always a wonderful stay. Great staff, comfortable room and great restaurant."
Canada
John
The price is NZ$295
includes taxes & fees
23 Feb - 24 Feb
Zocalo Central & Rooftop Mexico City

Holiday Inn Mexico Dali Airport by IHG

Holiday Inn Mexico Dali Airport by IHG
4.0 star property
Venustiano Carranza, 9.9 km from Santo Domingo
9.2 out of 10, Wonderful, (1,002 reviews)
"Room was great and the staff were amazing, kindness and very helpful. Restaurant is really good."
Canada
Salomon
The price is NZ$255
includes taxes & fees
4 Feb - 5 Feb
Holiday Inn Mexico Dali Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Santo Domingo

Find the best Santo Domingo areas for the activities you enjoy most.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

Polanco

Visit the most diverse section of Mexico City for sophisticated shopping, dining, accommodations and sightseeing.

La Condesa

Enjoy 20th-century history in these two sections of Mexico City, with interesting art and architecture reflecting European influences.

Historic Center

Consider a visit to Palacio de Bellas Artes and take some time to enjoy the interesting museums during your time in Historic Center. If you want to see more of the city, jump on the metro at Allende Station or Bellas Artes Station.

Reforma

Consider a visit to Angel of Independence Monument and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.

Top Santo Domingo Hotel Reviews

Frequently asked questions

What is Santo Domingo like?
Travellers to Mexico City's Santo Domingo neighbourhood will be sure to enjoy a stay here.
How many hotels will I find in the Santo Domingo area?
Book one of Expedia's 5 hotels and other accommodation options in Santo Domingo and start exploring everything Mexico City has to offer.
If I need to cancel my hotel reservation in Santo Domingo, will I receive a refund?
Yes, most room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best deals available in Santo Domingo.
What are the top things to see and do in Santo Domingo?
Parroquia de San Juan Bautista, Casa del Teatro and Museo Diego Rivera Anahuacalli are just a few of the places to visit in and around Santo Domingo. While you're out sightseeing, Museo de la Ciudad and Hidalgo Plaza are a couple of additional sights to visit in Mexico City.

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