
South Carolina Midlands Pet-friendly Holidays
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to NZ$2,400 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top Pet-friendly South Carolina Midlands Hotels

La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St Florence SC
Stay at this business-friendly hotel in Florence. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
7.8/10 Good! (1,601 reviews)
Lobby is big and well kept. Clerk was barely friendly only as much as required. Our room (queen non smoking) was roomy. Cleaning staff sucks….tub had leftover hair, mirror spotted, floors were sticky…..under couch hadn’t been cleaned in a year….bathroom floor and under sink had pee and leftover lotion ...
Reviewed on 11 May 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
Stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Millwood Plantation Ruins and Palmetto ...
8/10 Very Good! (1,016 reviews)
The hotel is freshly renovated, feels very modern and the room even had a clothes steamer (which my daughter needed for a dress). Breakfast was well stocked and the staff friendly and helpful.
Reviewed on 10 May 2026

Hampton Inn Columbia I-26/Harbison Blvd.
101 Woodcross Dr Columbia SC
Stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.2/10 Wonderful! (1,007 reviews)
What a nice place to stay! Just 20 minutes to the U of SC campus. Staff was very friendly and accommodating during our few day stay. The room was very clean, updated, and a decent size. They offer a continental breakfast with coffee, yogurts, oatmeal with toppings and a few hot items that change ...
Reviewed on 10 May 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
