A group of men in red uniforms with gold accents, holding rifles and wearing kilts.

Cheap Hotels & Resorts in Southeast Missouri from NZ$108

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Missouri Cheap Hotels

Tonight
21 Oct - 22 Oct
Tomorrow
22 Oct - 23 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Southeast Missouri cheap hotels

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

1. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Troy
NZ$143
includes taxes & fees
2 Nov - 3 Nov
Pear Tree Inn Cape Girardeau West
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.
A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.
A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

2. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
United States
Cindy
NZ$140
includes taxes & fees
4 Nov - 5 Nov
Motel 6 Poplar Bluff, MO
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.
A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.
A Travel Inn and Suites with a brick facade, a flat roof, and a welcoming entrance.

3. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
United States
Craig
NZ$123
includes taxes & fees
22 Oct - 23 Oct
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.
A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.
A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.
A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.

4. Town House Inn

Town House Inn
Jackson
United States
Jennifer
Town House Inn
A hotel room with a brick exterior, a sliding glass door, a window with a view, and a built-in heater.
A parking lot with a sign for 'Rosener's Inn' and a flagpole with an American flag.
A motel with a covered parking area, brick pillars, and a sign indicating it is a motel office.
A motel sign with "ROSENER'S INN" written on it.

5. Rosener's Inn and banquet center

Rosener's Inn and banquet center
Park Hills
United States
Jose
NZ$138
includes taxes & fees
25 Oct - 26 Oct
Rosener's Inn and banquet center
A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.
A wooden deck with a railing leading to a building with a metal roof and a brown door.
Front of property
A calm lake with a wooden dock and a forested island in the distance.

6. Lake Wappapello

Lake Wappapello
Williamsville
United States
Tonya
NZ$167
includes taxes & fees
22 Oct - 23 Oct
Lake Wappapello
A single-story house with a front porch, a chimney, and a well-maintained lawn.
A compact kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, an oven, and a toaster.
A bedroom with a bed, a ceiling fan, a chair, and a window with curtains.
A living room with a sectional sofa, a coffee table, a television mounted on the wall, and a floor lamp.

7. AV Bungalows #2

AV Bungalows #2
Arcadia
United States
Jill B.
NZ$500
includes taxes & fees
21 Nov - 22 Nov
AV Bungalows #2
A hotel room with a bed, two bedside tables, a ceiling fan, and two wall-mounted lamps.
A small kitchenette with a microwave, a sink, and a bench.
A reception area with a dark wooden counter, a water dispenser, potted plants, and a large window with an eagle mural.
A motel with a blue roof, a digital signboard, and a handicap parking space.

8. Motel 6 Sullivan, MO

Motel 6 Sullivan, MO
Sullivan
United States
Dane
NZ$144
includes taxes & fees
23 Oct - 24 Oct
Motel 6 Sullivan, MO
A hotel room with two beds, a desk, a chair, a lamp, and a painting on the wall.
A spacious indoor area with a reception desk, a dining table with chairs, a ceiling fan, and a television mounted on the wall.
A white bathtub with chrome fixtures and a shower curtain.
A reception area with a wooden reception desk, a sign indicating complimentary breakfast availability, and a ceiling fan.

9. Americas Best Value Inn Sullivan

Americas Best Value Inn Sullivan
Sullivan
United States
Emil
NZ$134
includes taxes & fees
23 Oct - 24 Oct
Americas Best Value Inn Sullivan
A hotel room with two beds, a desk, a chair, a dresser, and a TV.
Two white cups of coffee on a reflective black surface with a glass of milk in the background.
A modern building with a brick facade and a green roof.
A swimming pool with clear blue water, surrounded by lounge chairs and a fenced area.

10. Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
Fenton
United States
William
NZ$161
includes taxes & fees
27 Oct - 28 Oct
Wingate by Wyndham St. Louis/Fenton Route 66
View all properties

Top Southeast Missouri Hotel Reviews

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

10/10 Excellent
"Super clean and helpful friendly staff. Rooms are a bit small but still nice and modern. Only downside was no breakfast."
Sarah 1-night trip
Posted 19 hours ago
Motel 6 Poplar Bluff, MO
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"Stayed here for a long weekend motorcycle trip. The hotel is conveniently located near many shopping and dining choices. The room was basic but clean and quiet, and lots of channels on the tv! Staff were super friendly and helpful. I will definitely stay here again the next time I am in Cape Girardeau."
Robert 3-night trip
Posted 2 days ago
Pear Tree Inn Cape Girardeau West
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"good, clean, affordable :)"
Nicholas 1-night trip
Posted 8 days ago
Super 8 by Wyndham Sikeston/Miner Area

Explore a world of travel with Expedia