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Our top choices for Southeast Missouri hotels
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1006)
Explore Shawnee National Forest from this Cape Girardeau hotel offering complimentary breakfast, WiFi, and parking. Enjoy the indoor pool and spa pool after a day out, or dine at The Southerner restaurant. Each room includes handy refrigerators and microwaves.
"This Drury is our preferred place to stay when visiting family in Cape Girardeau. The hotel Staff is always warm and small town friendly! The hotel is nice and the breakfast buffet is outstanding!! "
Michael
The price is NZ$176
includes taxes & fees
6 Jan - 7 Jan
8.8 out of 10, Excellent, (467)
Surrounded by tranquil environments for rest and relaxation, this Caruthersville hotel offers gaming excitement at the on-site casino. Clean rooms and helpful staff earn praise from guests, while Century Casino and the public library wait just minutes away.
"Clean room, very nice staff"
Mack
The price is NZ$169
includes taxes & fees
3 Jan - 4 Jan
Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (861)
"The size of the room. The staff were great. The room was very clean. Will definitely stay there again."
Brenda
The price is NZ$204
includes taxes & fees
9 Jan - 10 Jan
9.6 out of 10, Exceptional, (1004)
This quiet retreat offers an indoor pool for morning swims and a relaxing spa pool to end your day. Clean rooms provide a peaceful atmosphere near Litz Park and Lazy L Safari Park, with free breakfast, WiFi, and parking to enhance your stay.
"Breakfast was great- staff was welcoming. Will stay there again."
Laura
The price is NZ$152
includes taxes & fees
4 Jan - 5 Jan
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
9.2 out of 10, Wonderful, (547)
Modern accommodation near Perryville Country Club featuring an indoor pool for morning swims and a 24-hour fitness centre. Enjoy complimentary breakfast, WiFi and parking while exploring nearby Saint Marys Lake. Travellers praise the clean rooms and helpful staff.
"lean, updated rooms, friendly staff and great breakfast."
Linda
The price is NZ$181
includes taxes & fees
4 Jan - 5 Jan
8.0 out of 10, Very good, (1004)
Enjoy a welcoming stay at this motel with free WiFi and parking near North Main Street Historic District. Staff receives praise for helpfulness, while convenient access to Margaret Harwell Art Museum enriches your Poplar Bluff experience.
"It was a nice stay."
Rebecca
The price is NZ$145
includes taxes & fees
10 Jan - 11 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Southeast Missouri, MO
Showing deals for:9 Jan - 11 Jan
Image gallery for Johnson's Shut-ins State Park
Johnson's Shut-ins State Park
Middle Brook
10/10Exceptional (1 review)
Member Price available
Price is NZ$977
for 2 nights, 1 cabin
NZ$488 per night
includes taxes & fees
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Stay near popular Central United States attractions
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Lake Wappapello State Park.
Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
10/10 Excellent
More cheap accommodation in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is NZ$106 per night from 16 Jan to 17 Jan
NZ$106
16 Jan - 17 Jan
includes taxes & fees
7.8/10 Good! (1,009 reviews)
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