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Check prices for these dates
Tonight
17 Aug - 18 AugTomorrow
18 Aug - 19 AugThis weekend
21 Aug - 23 AugNext weekend
28 Aug - 30 AugOur top choices for Southeast Missouri hotels
1. Shepherd Mountain Inn
Shepherd Mountain InnIronton
Katie
NZ$229
includes taxes & fees
18 Aug - 19 Aug
2. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
Jamie
NZ$144
includes taxes & fees
23 Aug - 24 Aug
3. Fort Davidson Hotel
Fort Davidson HotelIronton
richard
NZ$232
includes taxes & fees
18 Aug - 19 Aug
4. Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
Louise
NZ$188
includes taxes & fees
23 Aug - 24 Aug
5. Madison Inn Lodge
Madison Inn LodgeFredericktown
Christine
NZ$162
includes taxes & fees
18 Aug - 19 Aug
6. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
JoAnn
NZ$191
includes taxes & fees
23 Aug - 24 Aug
7. EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
JANEEN
NZ$148
includes taxes & fees
18 Aug - 19 Aug
8. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
Joni
NZ$194
includes taxes & fees
23 Aug - 24 Aug
9. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
Arsenia
NZ$194
includes taxes & fees
23 Aug - 24 Aug
10. Holiday Inn Express & Suites Farmington by IHG
Holiday Inn Express & Suites Farmington by IHGFarmington
Shawn
NZ$194
includes taxes & fees
23 Aug - 24 Aug
11. Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
Philip
NZ$178
includes taxes & fees
13 Sept - 14 Sept
12. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
Sally
NZ$183
includes taxes & fees
23 Aug - 24 Aug
13. Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MOFarmington
Kellie
NZ$106
includes taxes & fees
23 Aug - 24 Aug
14. Super 8 by Wyndham Farmington
Super 8 by Wyndham FarmingtonFarmington
Saundra
NZ$110
includes taxes & fees
23 Aug - 24 Aug
15. The Riverview
The RiverviewCape Girardeau
James
NZ$206
includes taxes & fees
25 Aug - 26 Aug
16. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
Ronrecus
NZ$242
includes taxes & fees
23 Aug - 24 Aug
17. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
Kevin
NZ$155
includes taxes & fees
18 Aug - 19 Aug
18. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
Heather
NZ$194
includes taxes & fees
23 Aug - 24 Aug
19. Perryville RV Resort
Perryville RV ResortPerryville
Von
NZ$129
includes taxes & fees
18 Aug - 19 Aug
20. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
michael
NZ$186
includes taxes & fees
23 Aug - 24 Aug
Holiday Rentals in Southeast Missouri
Cabin
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
"I really enjoyed my time at the stay !"
Holiday Home
Tiny Houses of French Village
Tiny Houses of French VillageFrench Village
"Very nice place very clean well kept inside an out it's a nice little romantic getaway they have it set up so great its a must see sunset very relaxing "
Cottage
'turtle Rock' - Ironton Cabin w/ Furnished Patio!
'turtle Rock' - Ironton Cabin w/ Furnished Patio!Ironton
"Stroller, pack n play and high chair. This was amazing "
Aparthotel
The Atrium - A Boutique Hotel
The Atrium - A Boutique HotelPerryville
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."
Cottage
Walk to Dtwn: Ironton Home in Historic District
Walk to Dtwn: Ironton Home in Historic DistrictIronton
"Clean and comfortable "
Cottage
40-acre Poplar Bluff Nature Lovers Paradise!
40-acre Poplar Bluff Nature Lovers Paradise!Poplar Bluff
"Beautiful place enjoyed our stay"
Cottage
Walk to Current River: Ozarks Adventure Home!
Walk to Current River: Ozarks Adventure Home!Van Buren
"Teresa & Chuck went out of their way to make the stay EXCELENT. Teresa is a great cook and shared some of her creations with me, again EXCELENT. The lodging was comfortable and easy to access. Next time in town that will be the place for me."
Cottage
Cozy Belgrade Cottage w/ Wood-burning Stove!
Cozy Belgrade Cottage w/ Wood-burning Stove!Belgrade
Cottage
Cottage w/ Yard, Walk to Historic Attractions
Cottage w/ Yard, Walk to Historic AttractionsSte Genevieve
"The little blue cottage was very comfortable, clean and close to everything downtown. We parked the car and walked everywhere. It was on a quiet street. The bed was comfy, clean kitchen. We liked the little back yard, for relaxing. "
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Stay near popular Southeast Missouri attractions
Photo by Pat Long
Elephant Rocks State Park
9.6/10 (98 reviews)
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
Southeast Missouri State University
8.8/10 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
Photo by JG Morris
Lake Wappapello
8.8/10 (54 reviews)
Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.
Century Casino & Hotel Cape Girardeau
8.4/10 (176 reviews)
Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your time in Cape Girardeau? While in this family-friendly area, you can savour the top-notch restaurants.
Century Casino Caruthersville
7.0/10 (57 reviews)
Why not try your luck with a visit to Century Casino Caruthersville during your visit to Caruthersville? While in this family-friendly area, you can enjoy the restaurants.
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.
See all hotels in Southeast Missouri
Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Recent Reviews in Southeast Missouri
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
"Great room, great breakfast. Friendly, helpful staff."
Baymont Inn and Suites by Wyndham Farmington, MO
10/10 Excellent
"The staff were very helpful. The room was in good shape."
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
10/10 Excellent
"Excellent experience here. No complaints or concerns. Our travels in the next six weeks will include this hotel chain because of this experience!"
Drury Inn & Suites Sikeston, MO
10/10 Excellent
"very nice staff and good food"
Candlewood Suites Cape Girardeau by IHG
10/10 Excellent
"Property was clean a room was stocked. Had microwave refrigerator and a stove refrigerator had working ice maker. Great room for the price"
Comfort Inn Festus - St Louis South
10/10 Excellent
"I always choose to stay here when visiting family. This stay was as always a delight."
Fairfield Inn & Suites by Marriott Poplar Bluff
10/10 Excellent
"Clean room help staff basic breakfast, but was good parking. Plenty easy to reach."
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
10/10 Excellent
"It was a very unique and great experience! Would definitely recommend to others."
Silo Farm Haus- located in the heart of wine country!
10/10 Excellent
"Our stay at the Silo House was absolutely wonderful! The home and surrounding property are stunning, and the peaceful setting made it the perfect escape from the hustle and bustle of everyday life. If you’re looking for a place to truly relax and recharge, this is it.My favorite part of the entire stay was starting each morning on the porch swing, watching the sunrise while listening to the sounds of nature. It was such a calming and memorable experience.The house itself was immaculate and thoughtfully equipped with every amenity you could possibly need. It was clear that every detail had been considered to make guests feel comfortable and at home.We couldn’t have asked for a better getaway and would absolutely stay here again. Highly recommend the Silo House to anyone looking for a peaceful, beautiful retreat!"
More cheap accommodation in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
NZ$106
23 Aug - 24 Aug
includes taxes & fees
8/10 Very good! (1,008 reviews)
Comfort Inn Festus - St Louis South
1303 Veterans Blvd Festus MO
NZ$120
7 Sept - 8 Sept
includes taxes & fees
7.8/10 Good! (987 reviews)
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
NZ$123
13 Sept - 14 Sept
includes taxes & fees
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
NZ$150
19 Aug - 20 Aug
includes taxes & fees
The Farmstead Hotel
778 E 3rd St Caruthersville MO
NZ$151
28 Aug - 29 Aug
includes taxes & fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
NZ$211
20 Aug - 21 Aug
includes taxes & fees
9.4/10 Exceptional! (1,004 reviews)
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