Southeast Missouri Holidays

Book a Hotel + Flight or Car together to unlock savings

Choose two or more items and save on your trip:
    Plan, book, travel with confidence
  • payments icon
    Better together
    Save up to NZ$545 when you book a flight and hotel together*
  • lob hotels icon
    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • lob packages icon
    Rest easy
    Plan, book, and manage your trip all in one place

Our pick of the best Southeast Missouri Hotel Deals

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is NZ$121 per night from 9 Jun to 10 Jun
NZ$121
per night
9 Jun - 10 Jun
8.8/10 Excellent! (1,001 reviews)
One night in Cape Girardeau
"There are two Pear Tree Inns in Cape G. We enjoyed the comfortable bed and pillows. No eggs, bacon at the breakfast but offers were good"

Reviewed on 22 May 2024

Pear Tree Inn Cape Girardeau West
Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
2.5 out of 5
3265 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is NZ$125 per night from 3 Jun to 4 Jun
NZ$125
per night
3 Jun - 4 Jun
8.6/10 Excellent! (1,003 reviews)
"Staff and premises were top knotch.i had family come vist and swim for a bit and they were welcoming to my guest.The manager and staff complimented eachother.very good work= physicaly and socially..room was clean smelled good nothing out of place.. I DIDNT WANT TO LEAVE!! LOL THANK YOU FOLKS FOR ..."

Reviewed on 21 May 2024

Auburn Place Hotel And Suites
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is NZ$126 per night from 30 May to 31 May
NZ$126
per night
30 May - 31 May
7/10 Good! (1,001 reviews)
A good place to stay
"Check-in and check-out went smoothly. The hotel was quiet and comfortable. The check-in clerk recommended a restaurant in town where we ate some of the best Mexican food I have ever eaten. She was also very friendly and quick. The duck families crossing the road to the pond as we left was just another ..."

Reviewed on 21 May 2024

Days Inn and Suites by Wyndham Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Southeast Missouri holiday package cost?
Cross off another part of the world with our Southeast Missouri holiday packages, which start from just . Select the flights and hotels that match your travel plans. Then, add on one or two tours or experiences for an unforgettable adventure.
How do I get a cheap travel package to Southeast Missouri?
Browse and book everything in the one place with our Southeast Missouri holiday packages. You’ll find deals on flights, hotels, tours and more that’ll keep your pocket happy and your adventurous spirit alive. And, with more than 550 partner airlines and 1 000 000 hotels around the world to select from, you’ll have endless opportunities to mix and match your own way.
What are the top hotels in Southeast Missouri?
When it comes to properties in Cape Girardeau, Drury Plaza Hotel Cape Girardeau Conference Centre and Pear Tree Inn Cape Girardeau West are a couple of favourites. If you’re considering heading to Ste Genevieve, City Place St. Louis Downtown and The Branson Hillside Hotel are waiting to welcome you.
How far in advance should I book my Southeast Missouri holiday?
It’s tricky picking the perfect time for airfares, but we generally say the earlier, the better. Many international journeys on Expedia become available up to a year in advance. If you can’t book ahead, don’t worry. Cheap prices appear from time to time within a few weeks of departure dates.
What does an Expedia Southeast Missouri travel package include?
From hotels and flights to car rentals, Expedia can help you craft a Southeast Missouri package that fits you. Holidaying for a week or two? Look into a rental car, hotel and flight bundle. If you’re taking a quick break, a hotel and airfare deal may suit you better. Experiences can also be added once you’ve made your booking. Our packages make it a breeze to plan and save.
What should I know before booking a Southeast Missouri travel package?
When you book your flights, hotels and car rentals together, you’ll pick up terrific discounts. Whether you’re planning a beach escape in a villa or prefer to stay in a comfortable hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Southeast Missouri Expedia holiday package?
You can, and with over 550 airlines to pick from around the world, you’re spoiled for choice. Have a look through the available options and see which airline best suits your budget and needs.
If I'm not able to travel, can I cancel my Southeast Missouri holiday package?
Because we understand life is full of surprises, the answer is yes. To learn more, head to our Customer Service Portal. But generally speaking, if you’ve booked your Southeast Missouri holiday package in the last 24 hours, you may be able to cancel or change it for no charge. Your hotel, airline or car rental company may charge a fee if your booking is older than that.

Discover the most popular places to visit in Southeast Missouri

What to do in Southeast Missouri

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.