Southeast Missouri Holidays

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    Save up to NZ$616 when you book a flight and hotel together*
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Southeast Missouri Holiday

Our pick of the best Southeast Missouri Hotel Deals

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St, Farmington, MO
Fully refundableReserve now, pay when you stay
The price is NZ$108 per night from 14 Aug to 15 Aug
NZ$108
14 Aug - 15 Aug
includes taxes & fees
8/10 Very Good! (1,008 reviews)
"Fair prices and nice staff well taken care ofby the Baymont family"

Reviewed on 30 Jul. 2025

Baymont Inn and Suites by Wyndham Farmington, MO
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is NZ$201 per night from 6 Aug to 7 Aug
NZ$201
6 Aug - 7 Aug
includes taxes & fees
9.2/10 Wonderful! (369 reviews)
"A very cool destination!"

Reviewed on 1 Aug. 2025

The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is NZ$194 per night from 10 Aug to 11 Aug
NZ$194
10 Aug - 11 Aug
includes taxes & fees
9.4/10 Exceptional! (1,003 reviews)
"The property was clean and well staffed. They offered various food and drink options from the time we checked in until the time we checked out. Great staff great hotel and a wonderful experience!"

Reviewed on 1 Aug. 2025

Drury Plaza Hotel Cape Girardeau Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Southeast Missouri

What to do in Southeast Missouri

Frequently asked questions

How much does a Southeast Missouri holiday package cost?
Cross off another part of the world with our Southeast Missouri holiday packages, which start from just . Select the flights and hotels that match your travel plans. Then, add on one or two tours or experiences for an unforgettable adventure.
How do I get a cheap travel package to Southeast Missouri?
Browse and book everything in the one place with our Southeast Missouri holiday packages. You'll find deals on flights, hotels, tours and more that'll keep your pocket happy and your adventurous spirit alive. And, with more than 550 partner airlines and 1 000 000 hotels around the world to select from, you'll have endless opportunities to mix and match your own way.
What are the top hotels in Southeast Missouri?
When it comes to properties in Cape Girardeau, Drury Plaza Hotel Cape Girardeau Conference Centre and Pear Tree Inn Cape Girardeau West are a couple of favourites. If you're considering heading to Ste Genevieve, City Place St. Louis Downtown and The Branson Hillside Hotel are waiting to welcome you.
How far in advance should I book my Southeast Missouri holiday?
It's tricky picking the perfect time for airfares, but we generally say the earlier, the better. Many international journeys on Expedia become available up to a year in advance. If you can't book ahead, don't worry. Cheap prices appear from time to time within a few weeks of departure dates.
What does an Expedia Southeast Missouri travel package include?
From hotels and flights to car rentals, Expedia can help you craft a Southeast Missouri package that fits you. Holidaying for a week or two? Look into a rental car, hotel and flight bundle. If you're taking a quick break, a hotel and airfare deal may suit you better. Experiences can also be added once you've made your booking. Our packages make it a breeze to plan and save.
What should I know before booking a Southeast Missouri travel package?
When you book your flights, hotels and car rentals together, you'll pick up terrific discounts. Whether you're planning a beach escape in a villa or prefer to stay in a comfortable hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Southeast Missouri Expedia holiday package?
You can, and with over 550 airlines to pick from around the world, you're spoiled for choice. Have a look through the available options and see which airline best suits your budget and needs.
If I'm not able to travel, can I cancel my Southeast Missouri holiday package?
Because we understand life is full of surprises, the answer is yes. To learn more, head to our Customer Service Portal. But generally speaking, if you've booked your Southeast Missouri holiday package in the last 24 hours, you may be able to cancel or change it for no charge. Your hotel, airline or car rental company may charge a fee if your booking is older than that.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.