South Main Hotels, Houston

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Tonight
25 Sept - 26 Sept
Tomorrow
26 Sept - 27 Sept
This weekend
26 Sept - 28 Sept
Next weekend
3 Oct - 5 Oct

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6550 Cheap Hotels in South Main - Specials, Reviews, & Last Minute Deals

Wyndham Houston near NRG Park/Medical Center
Lobby

Wyndham Houston near NRG Park/Medical Center

3.5 star property
7.2 out of 10, Good, (1164)
"I use the app and its been really helpful for our trips we have planned so far."
The price is NZ$197
includes taxes & fees
26 Sept - 27 Sept
Wyndham Houston near NRG Park/Medical Center
Candlewood Suites Houston Medical Center by IHG
Exterior

Candlewood Suites Houston Medical Center by IHG

2.5 star property
7.4 out of 10, Good, (798)
"The staff is great. The area is questionable due to homeless population."
The price is NZ$156
includes taxes & fees
28 Sept - 29 Sept
Candlewood Suites Houston Medical Center by IHG
Wingate Houston near NRG Park/Medical Center
Gazebo

Wingate Houston near NRG Park/Medical Center

3.0 star property
6.6 out of 10, (940)
"Walking distance to NRG Stadium "
The price is NZ$158
includes taxes & fees
4 Oct - 5 Oct
Wingate Houston near NRG Park/Medical Center
Quality Inn & Suites NRG Park - Medical Center
1 bedroom, hypo-allergenic bedding, in-room safe, individually decorated

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
6.6 out of 10, (1008)
"Wonderful experience absolutely love my stay"
The price is NZ$125
includes taxes & fees
8 Oct - 9 Oct
Quality Inn & Suites NRG Park - Medical Center
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
Pillow-top beds, desk, iron/ironing board, WiFi

La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd

3.5 star property
9.2 out of 10, Wonderful, (1010)
"Clean and comfortable hotel"
The price is NZ$147
includes taxes & fees
26 Oct - 27 Oct
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
Champions Club and Hotel, Houston Westchase
Breakfast, lunch and dinner served

Champions Club and Hotel, Houston Westchase

4.0 star property
9.0 out of 10, Wonderful, (448)
"Great place to stay"
Champions Club and Hotel, Houston Westchase
Blossom Hotel Houston
Front of property

Blossom Hotel Houston

4.0 star property
9.0 out of 10, Wonderful, (3541)
"Great stay "
The price is NZ$293
includes taxes & fees
24 Oct - 25 Oct
Blossom Hotel Houston
Drury Inn & Suites Houston Near the Galleria
Lobby

Drury Inn & Suites Houston Near the Galleria

3.0 star property
9.4 out of 10, Exceptional, (1233)
"Love this place ide so stay again and recommend "
The price is NZ$188
includes taxes & fees
16 Oct - 17 Oct
Drury Inn & Suites Houston Near the Galleria
Houston Marriott South at Hobby Airport
Lobby

Houston Marriott South at Hobby Airport

3.5 star property
8.8 out of 10, Excellent, (1240)
"Great clean stay , very quiet and close to the airport "
The price is NZ$171
includes taxes & fees
26 Sept - 27 Sept
Houston Marriott South at Hobby Airport
La Quinta Inn & Suites by Wyndham Houston NW Beltway8/WestRD
Coffee service

La Quinta Inn & Suites by Wyndham Houston NW Beltway8/WestRD

3.0 star property
9.0 out of 10, Wonderful, (935)
"The staff was AMAZING."
The price is NZ$163
includes taxes & fees
27 Sept - 28 Sept
La Quinta Inn & Suites by Wyndham Houston NW Beltway8/WestRD
The Chifley Houston, Tapestry Collection by Hilton
Lobby

The Chifley Houston, Tapestry Collection by Hilton

4.0 star property
9.2 out of 10, Wonderful, (1110)
"excellent hotel, spacious rooms"
The price is NZ$321
includes taxes & fees
10 Oct - 11 Oct
The Chifley Houston, Tapestry Collection by Hilton
The Laura Hotel, Houston Downtown, Autograph Collection
Egyptian cotton sheets, premium bedding, pillow-top beds, in-room safe

The Laura Hotel, Houston Downtown, Autograph Collection

4.5 star property
9.0 out of 10, Wonderful, (1013)
"Great place to stay!"
The price is NZ$432
includes taxes & fees
26 Sept - 27 Sept
The Laura Hotel, Houston Downtown, Autograph Collection
Palace Inn 290 & Jones Rd
Room, 1 King Bed, Non Smoking | View from room

Palace Inn 290 & Jones Rd

2.5 star property
8.8 out of 10, Excellent, (472)
"Good staff and safe "
The price is NZ$108
includes taxes & fees
29 Sept - 30 Sept
Palace Inn 290 & Jones Rd
La Quinta Inn & Suites by Wyndham Houston Channelview
Exterior

La Quinta Inn & Suites by Wyndham Houston Channelview

3.5 star property
8.6 out of 10, Excellent, (812)
"Excellent and friendly staff "
The price is NZ$165
includes taxes & fees
28 Sept - 29 Sept
La Quinta Inn & Suites by Wyndham Houston Channelview
Haven Inn & Suites Downtown Houston
Premium bedding, desk, iron/ironing board, free WiFi

Haven Inn & Suites Downtown Houston

2.5 star property
9.4 out of 10, Exceptional, (1012)
"Was great stay."
Haven Inn & Suites Downtown Houston
Hampton Inn & Suites Houston-Bush Intercontinental Aprt
Exterior

Hampton Inn & Suites Houston-Bush Intercontinental Aprt

3.0 star property
8.8 out of 10, Excellent, (1546)
"Clean spacious wheelchair accessible room, friendly helpful staff, good breakfast"
The price is NZ$165
includes taxes & fees
5 Oct - 6 Oct
Hampton Inn & Suites Houston-Bush Intercontinental Aprt
Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham
Lobby

Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham

3.0 star property
8.8 out of 10, Excellent, (1021)
"Clean and good place to stay "
The price is NZ$166
includes taxes & fees
28 Sept - 29 Sept
Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham
Hyatt Regency Houston/Galleria
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, pool loungers

Hyatt Regency Houston/Galleria

4.0 star property
9.0 out of 10, Wonderful, (1068)
" Good hotel"
The price is NZ$338
includes taxes & fees
23 Oct - 24 Oct
Hyatt Regency Houston/Galleria
Omni Houston Hotel
Interior

Omni Houston Hotel

4.0 star property
9.0 out of 10, Wonderful, (1015)
"Enjoyed the stay "
The price is NZ$345
includes taxes & fees
18 Oct - 19 Oct
Omni Houston Hotel
Prestige Inn
Lobby sitting area

Prestige Inn

2.5 star property
8.6 out of 10, Excellent, (250)
"Good experience "
Prestige Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in South Main

Find the best South Main areas for the activities you enjoy most.
Discovery Green which includes a high-rise building, a square or plaza and a city

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Menil Collection showing interior views and art

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Houston showing a high-rise building and a city

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Top South Main Hotel Reviews

Heritage Place Houston Brookhollow

Heritage Place Houston Brookhollow

10/10 Excellent
"The pool was nice staff nice hotel was clean and smelt wonderful "
Lisa 1-night trip
Posted 2 days ago
Heritage Place Houston Brookhollow

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is South Main like?

You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighbourhood include Candlewood Suites Houston Medical Center by IHG and Quality Inn & Suites NRG Park - Medical Center.

How many hotels should I expect to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 64 South Main hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.

What can I see and do in this Houston neighbourhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.