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South Main Hotels, Houston

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6449 Cheap Hotels in South Main - Specials, Reviews, & Last Minute Deals

Wyndham Houston near NRG Park/Medical Center

3.5 star property
7.2 out of 10, Good, (1133)
"A well kept hotel with great service and atmosphere."
The price is NZ$163
includes taxes & fees
25 July - 26 July
Wyndham Houston near NRG Park/Medical Center

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
6.4 out of 10, (1011)
"Great place to stay right next to the NRG stadium "
The price is NZ$114
includes taxes & fees
23 Aug - 24 Aug
Quality Inn & Suites NRG Park - Medical Center

Wingate Houston near NRG Park/Medical Center

3.0 star property
6.6 out of 10, (927)
"Great location, rooms were hot/warm. Needs a huge make over."
The price is NZ$130
includes taxes & fees
31 July - 1 Aug
Wingate Houston near NRG Park/Medical Center

Candlewood Suites Houston Medical Center by IHG

2.5 star property
7.4 out of 10, Good, (786)
"Will definitely be back again!"
The price is NZ$145
includes taxes & fees
8 Aug - 9 Aug
Candlewood Suites Houston Medical Center by IHG

La Quinta Inn & Suites by Wyndham Deer Park

3.0 star property
8.4 out of 10, Very good, (396)
"For the price, best in Deer Park"
The price is NZ$163
includes taxes & fees
24 Aug - 25 Aug
La Quinta Inn & Suites by Wyndham Deer Park

La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd

3.5 star property
9.2 out of 10, Wonderful, (996)
"Amazing staff and amazing property overall!"
The price is NZ$137
includes taxes & fees
24 Aug - 25 Aug
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd

Sonesta Simply Suites Houston – NASA Clear Lake

2.5 star property
8.2 out of 10, Very good, (967)
"I always enjoy my extended stay in Sonesta at Clear Lake. The property is well maintained, the staff is caring and friendly and the location is very good."
The price is NZ$112
includes taxes & fees
7 Aug - 8 Aug
Sonesta Simply Suites Houston – NASA Clear Lake

SureStay Hotel by Best Western Deer Park

2.5 star property
8.4 out of 10, Very good, (247)
"Good Place to stay "
The price is NZ$137
includes taxes & fees
28 July - 29 July
SureStay Hotel by Best Western Deer Park

Platinum Inn & Suites Webster

2.5 star property
8.0 out of 10, Very good, (37)
"Very good staff, always attended to needs quickly. Wonderful place to stay. "
The price is NZ$130
includes taxes & fees
29 July - 30 July
Platinum Inn & Suites Webster

Best Western Webster Hotel, Nasa

2.5 star property
7.6 out of 10, Good, (1006)
"Great stay"
The price is NZ$124
includes taxes & fees
7 Aug - 8 Aug
Best Western Webster Hotel, Nasa

La Quinta Inn & Suites by Wyndham Houston Channelview

3.5 star property
8.4 out of 10, Very good, (776)
"Convenient location "
The price is NZ$173
includes taxes & fees
24 Aug - 25 Aug
La Quinta Inn & Suites by Wyndham Houston Channelview

La Quinta Inn & Suites by Wyndham Pasadena North

3.0 star property
7.6 out of 10, Good, (596)
"Will go again I like this hotel!!!!"
The price is NZ$156
includes taxes & fees
10 Aug - 11 Aug
La Quinta Inn & Suites by Wyndham Pasadena North

Bluestar Inn

2.5 star property
9.0 out of 10, Wonderful, (252)
"Nice place at a good rate "
The price is NZ$113
includes taxes & fees
28 July - 29 July
Bluestar Inn

Best Western Plus Pasadena Inn and Suites

2.5 star property
8.6 out of 10, Excellent, (422)
"Excellent place to stay"
The price is NZ$179
includes taxes & fees
3 Aug - 4 Aug
Best Western Plus Pasadena Inn and Suites

Best Western Plus Heritage Inn

3.0 star property
8.0 out of 10, Very good, (698)
"The best stay i have ever had ! "
The price is NZ$152
includes taxes & fees
9 Aug - 10 Aug
Best Western Plus Heritage Inn

Woodspring Suites South Houston Hobby

2.5 star property
8.0 out of 10, Very good, (244)
"Nice stay"
The price is NZ$125
includes taxes & fees
27 July - 28 July
Woodspring Suites South Houston Hobby

Palace Inn Blue Edgebrook

2.5 star property
9.6 out of 10, Exceptional, (126)
"Really great hospitality"
The price is NZ$155
includes taxes & fees
27 July - 28 July
Palace Inn Blue Edgebrook

Sonesta Essential Houston Hobby Airport

2.5 star property
6.4 out of 10, (1007)
"I love the breakfast."
The price is NZ$126
includes taxes & fees
26 July - 27 July
Sonesta Essential Houston Hobby Airport

Days Inn & Suites by Wyndham Houston Hobby Airport

2.5 star property
8.6 out of 10, Excellent, (1003)
"It was good stay"
The price is NZ$172
includes taxes & fees
3 Aug - 4 Aug
Days Inn & Suites by Wyndham Houston Hobby Airport

Houston Marriott South at Hobby Airport

3.5 star property
8.8 out of 10, Excellent, (1149)
"The location was great."
The price is NZ$166
includes taxes & fees
26 July - 27 July
Houston Marriott South at Hobby Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in South Main

Find the best South Main areas for the activities you enjoy most.
Downtown Houston map

Downtown Houston

3 out of top 10 points of interest in this area

Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria map

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center map

Texas Medical Center

1 out of top 10 points of interest in this area

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Montrose map

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Houston Central Business District map

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Top South Main Hotel Reviews

Frequently asked questions

What is South Main like?

You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighbourhood include Candlewood Suites Houston Medical Center by IHG and Quality Inn & Suites NRG Park - Medical Center.

How many hotels should I expect to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 61 South Main hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.

What can I see and do in this Houston neighbourhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.