South Main Travel Guide
Tourist Guide


Visit South Main
Activities

Houston's Official City & Mural Tour!

NASA's Space Center & Official Houston City Tour with tickets

Houston: Space Center Houston Admission Ticket

Houston: Museum of Natural Science General Admission Ticket

Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
Our pick of the best South Main Hotel Deals

Wyndham Houston near NRG Park/Medical Center
"Rooms were big and spacious. Clean, lots of towels. Front lobby has a weird smell but very beautiful furniture and lots of snacks and drinks to choose from."
Reviewed on 3 July 2026

Hotel Zaza Houston Museum District
"Nice"
Reviewed on 4 July 2026

Grand Tuscany Hotel
"A LOT OF CONSTRUCTION!! Getting off of the one elevator that worked that didn’t have AC btw..was like walking into a workshop. Paint brushes & paint cans, ladders..Construction noises. I def would’ve stayed somewhere else if I knew all that was going on"
Reviewed on 4 July 2026

Club Quarters Hotel Downtown, Houston
"Thanks, Staff for the kindness, attentiveness and clean water!"
Reviewed on 3 July 2026

Marriott Marquis Houston
"Location is excellent but the trade off is lots of noise and light pollution. Beware of hidden fees. Disappointing experience for the price."
Reviewed on 4 July 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
"I Didn’t Like The parkin & once i got checked in the next morning i tried to get coffee had to pay 4 for a cup & wasn’t complementary to breakfast i had to pay which i thought i had when i booked my room once i checked out this morning it wasn’t no cart to bring my belongings down from the 18th floor ..."
Reviewed on 4 July 2026
Our guide on where to stay in South Main

Downtown Houston
Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.





















