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Go beyond your typical stay in Panacea
Pet friendly
Villa
Apartment
Condo
Cottage
Family friendly
Waterpark
Check prices for these dates
Tonight
20 Aug - 21 AugTomorrow
21 Aug - 22 AugThis weekend
21 Aug - 23 AugNext weekend
28 Aug - 30 AugOur top choices for Panacea hotels




1. The Panacea Motel
The Panacea MotelPanacea
Michelle
NZ$210
includes taxes & fees
24 Aug - 25 Aug




2. Best Western Wakulla Inn & Suites
Best Western Wakulla Inn & SuitesCrawfordville
Lydia
NZ$194
includes taxes & fees
3 Sept - 4 Sept




3. Wildwood Inn
Wildwood InnCrawfordville
Megan
NZ$226
includes taxes & fees
8 Sept - 9 Sept




4. The Lodge at Wakulla Springs
The Lodge at Wakulla SpringsCrawfordville
Sherry
NZ$198
includes taxes & fees
24 Aug - 25 Aug




5. St James Bay Golf & Pickleball Resort
St James Bay Golf & Pickleball ResortCarrabelle
Mike
NZ$310
includes taxes & fees
21 Aug - 22 Aug




6. The Old Carrabelle Hotel
The Old Carrabelle HotelCarrabelle
David
NZ$196
includes taxes & fees
1 Sept - 2 Sept




7. The Moorings Hotel and Marina
The Moorings Hotel and MarinaCarrabelle
Tina
NZ$316
includes taxes & fees
25 Aug - 26 Aug




8. Franklin Inn
Franklin InnCarrabelle
Melynda
NZ$159
includes taxes & fees
23 Aug - 24 Aug
Stay near popular Panacea attractions
Alligator Point Beach
8.8/10 (10 reviews)
Escape to this pristine stretch of old coastal Florida with white sands and shallow, clear waters. Spot dolphins and sea turtles while enjoying the serenity of an undeveloped shoreline.
Bald Point State Park
8.6/10 (20 reviews)
Where Ochlockonee Bay meets Apalachee Bay, this coastal park showcases diverse ecosystems from beaches to pine flatwoods. Spot migrating raptors and monarch butterflies while hiking through pristine natural habitats.
Mashes Sand Beach
8.8/10 (3 reviews)
Mashes Sands Beach offers serene shallow waters and expansive sandbars perfect for peaceful exploration. Wade through the tea-colored Gulf waters while spotting hermit crabs and enjoying spectacular sunset views.
Wilson Beach
Wilson Beach offers a serene Gulf Coast escape with pristine shores and gentle waves far from tourist crowds. Bring supplies and enjoy peaceful beachcombing along this unspoiled natural sanctuary.
Panacea Springs
Once a popular health resort, these historic mineral springs were believed to possess healing properties in the early 1900s. Explore the remnants of spa structures while imagining the therapeutic rituals of a bygone era.
Public Beach Access
Mashes Sands Beach features tranquil white-sand shores and shallow waters ideal for families. Wade in the gentle surf, cast a fishing line, or enjoy a peaceful picnic away from tourist crowds.
Gulf Specimen Public Aquarum
Take the children to visit the sea life you'll find at Gulf Specimen Public Aquarum during your holiday to Panacea. Stroll along the beaches in this relaxing area or seek out the fishing spots.
Panacea Park
After visiting Panacea Park, make a plan to see the other sights and activities in Panacea. Stroll along this relaxing area's beaches or simply enjoy its seafood restaurants.
Learn more about Panacea
Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.
See all hotels in Panacea
Top Panacea Hotel Reviews
Recent Reviews in Panacea
Hideaway Beach Cottage on waterfront with amazing views.
10/10 Excellent
"Incredible experience all the way around !Clean, cozy, inviting and stellar communication!!"
Directly on the water, great sunrise and sunset.50% off monthly rate fall/winter
10/10 Excellent
"The property was amazing. We had a blast."
Bayfront/Ocean Views/Shared Boat Dock/Pets
8/10 Good
"Excellent, but it could have been even better! I rated it four stars because there was a foul odor left in the refrigerator by the previous tenant. The cleaning crew should have caught this. Also, there was no gas tank for the gas grill when we arrived. Molly took care of these things quickly once we were able to get through to her. We hope to return someday soon, and look forward to giving this wonderful place a five star review next time."
Best deal at Alligator Point
10/10 Excellent
"We had a clean, comfy, peaceful stay with a beautiful view!An attentive host! A deck w/ sunset views! Highly Recommend!Thank you for a wonderful stay!"
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
10/10 Excellent
"We had an amazing week. Best equipped home we have ever stayed. The privacy and peacefulness was just want we needed. Host was very responsive."
The Panacea Motel
10/10 Excellent
"I loved the retro feel of the place."
Gulf Breeze – Pet-Friendly 3BR Beachfront Stay with Stunning Views & Renovations
10/10 Excellent
"We’ve spent many years on Alligator Point, and this has to be our new favorite house to stay in. The guys fished from under the house most of the time. It was a wonderful trip!!"
Happy Shack BEACH & BAY! Kayak, paddle boards, tiki hut, firepit, grille, wifi
10/10 Excellent
"I just want to express my deepest gratitude for allowing us to stay in your beautiful home. From the moment we arrived, it brought such a sense of peace, calm, and relaxation — exactly what our family needed.Being able to paddleboard alongside the dolphins was absolutely incredible. It felt like we were in our own little world, surrounded by so much beauty and tranquility. The breathtaking sunrises, sunsets, and the precious quality time we shared together are memories we will cherish forever.Thank you again from the bottom of our hearts for opening your home to us and creating such a special place where we could reconnect, unwind, and enjoy every moment. We truly enjoyed our stay and are so grateful for this amazing experience."
5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch
10/10 Excellent
"Everyone had great time, house was very nice and accommodating for the whole family. Beds were very comfortable. Would definitely recommend mosquito spray though. Screened porch was a big plus for sitting outside at night. Overall a very peaceful place."
More cheap accommodation in Panacea

Franklin Inn
1589 US-98 Carrabelle FL
NZ$159
23 Aug - 24 Aug
includes taxes & fees
7.8/10 Good! (504 reviews)

Best Western Wakulla Inn & Suites
3292 Coastal Hwy 98 Crawfordville FL
NZ$194
3 Sept - 4 Sept
includes taxes & fees

The Old Carrabelle Hotel
201 Tallahassee St Carrabelle FL
NZ$196
1 Sept - 2 Sept
includes taxes & fees
9.6/10 Exceptional! (43 reviews)

The Panacea Motel
1545 Coastal Hwy Panacea FL
NZ$210
24 Aug - 25 Aug
includes taxes & fees
9/10 Wonderful! (188 reviews)

The Moorings Hotel and Marina
1000 Hwy 98 Carrabelle FL
NZ$316
25 Aug - 26 Aug
includes taxes & fees

Cozy Waterfront 'island House' on Live Oak Island!
Crawfordville FL
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