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Go beyond your typical stay in Panacea
Pet friendly
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Spa pool
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Family friendly
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Check prices for these dates
Tonight
5 Oct - 6 OctTomorrow
6 Oct - 7 OctThis weekend
9 Oct - 11 OctNext weekend
16 Oct - 18 OctOur top choices for Panacea hotels




1. The Panacea Motel
The Panacea MotelPanacea
Dashawn
NZ$222
includes taxes & fees
6 Oct - 7 Oct




2. Best Western Wakulla Inn & Suites
Best Western Wakulla Inn & SuitesCrawfordville
James
NZ$230
includes taxes & fees
18 Oct - 19 Oct




3. Wildwood Inn
Wildwood InnCrawfordville
Shane
NZ$238
includes taxes & fees
22 Oct - 23 Oct




4. The Lodge at Wakulla Springs
The Lodge at Wakulla SpringsCrawfordville
Joy
NZ$167
includes taxes & fees
6 Oct - 7 Oct




5. St James Bay Golf & Pickleball Resort
St James Bay Golf & Pickleball ResortCarrabelle
Richard
NZ$255
includes taxes & fees
6 Oct - 7 Oct




6. The Moorings Hotel and Marina
The Moorings Hotel and MarinaCarrabelle
Tina
NZ$253
includes taxes & fees
12 Oct - 13 Oct




7. The Old Carrabelle Hotel
The Old Carrabelle HotelCarrabelle
Christy
NZ$207
includes taxes & fees
18 Oct - 19 Oct
Stay near popular Panacea attractions
Alligator Point Beach
8.8/10 (10 reviews)
Escape to this pristine stretch of old coastal Florida with white sands and shallow, clear waters. Spot dolphins and sea turtles while enjoying the serenity of an undeveloped shoreline.
Bald Point State Park
8.6/10 (20 reviews)
Where Ochlockonee Bay meets Apalachee Bay, this coastal park showcases diverse ecosystems from beaches to pine flatwoods. Spot migrating raptors and monarch butterflies while hiking through pristine natural habitats.
Mashes Sand Beach
8.8/10 (3 reviews)
Mashes Sands Beach offers serene shallow waters and expansive sandbars perfect for peaceful exploration. Wade through the tea-colored Gulf waters while spotting hermit crabs and enjoying spectacular sunset views.
Wilson Beach
Wilson Beach offers a serene Gulf Coast escape with pristine shores and gentle waves far from tourist crowds. Bring supplies and enjoy peaceful beachcombing along this unspoiled natural sanctuary.
Public Beach Access
Mashes Sands Beach features tranquil white-sand shores and shallow waters ideal for families. Wade in the gentle surf, cast a fishing line, or enjoy a peaceful picnic away from tourist crowds.
Panacea Springs
Once a popular health resort, these historic mineral springs were believed to possess healing properties in the early 1900s. Explore the remnants of spa structures while imagining the therapeutic rituals of a bygone era.
Silver Lake
Swim in crystal-clear waters along a pristine 250-foot white sand beach surrounded by longleaf pines. The mile-long interpretive trail offers peaceful wildlife encounters with bald eagles and turtles.
Gulf Specimen Public Aquarum
Take the children to visit the sea life you'll find at Gulf Specimen Public Aquarum during your holiday to Panacea. Stroll along the beaches in this relaxing area or seek out the fishing spots.
Learn more about Panacea
Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.
See all hotels in Panacea
Top Panacea Hotel Reviews
Recent Reviews in Panacea
Tiki House is a Unique Beach Front gathering spot for family, friends and pups.
10/10 Excellent
"The house was very nice, and as advertised. Right on the beach."
5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch
10/10 Excellent
"Great place to stay very peaceful and relaxing."
Great sunrise view from dining area and decks. Easy beach access.
10/10 Excellent
"Property is clean and in a great location for peace and quiet. We enjoyed meeting the host and I'm sure will book with them again."
Lighthouse- enjoy the water, bask in the view
10/10 Excellent
"A very remote location, laid back small community and very natural beaches."
Hideaway Beach Cottage on waterfront with amazing views.
10/10 Excellent
"Booking this stay was incredibly easy. Hosts are responsive and very accommodating. Price was great, especially considering that we thought the property was even better in person. Pictures truly don’t do it justice. The small town of Panacea is a breath of fresh air. Not your typical touristy beach town. We wanted to have a slow, low stim vacation with our young kids and that’s exactly what we got. There are still enough restaurants to choose from if you want to eat out every night in the town and even more within a 20 minute drive. If you want to stay in and cook, the kitchen has plenty of room and is stocked well. Large dining table with more than enough room. The living area large and comfy. We didn’t use the second bedroom beds because our kids are still in pack and plays. Two fit in the room just fine. The master bedroom mattress was genuinely one of the most comfortable beds I’ve slept in. Screened in porch was amazing to relax in and let in 0 bugs somehow. So impressed. Our absolute favorite part though was the yard and little beach on the bay. Our kids can’t stand to be inside and they played for HOURS in the good sized yard. We watched stingrays, fish, and birds in the bay. The only thing I’d tell people to consider is that the beach can be a drive. The closest beach, Mashes Sands, had almost no shoreline so you’ll need to drive \- 20 minutes for a beach. This didn’t bother us at all. There is virtually no traffic and tons of options."
Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +
10/10 Excellent
"This was our third trip to this house for a week. Enjoyed everything.. you don't need anything."
Coastal Getaway on canal-steps to the beach
10/10 Excellent
"Awesome weekend staying at this location. We was within walking distance to the beach and fishing. Loved that it had a complete bathroom downstairs when we came in from fishing all day and night. Great communication with the host. Very prompt responding to questions. Will recommend to family and friends!!"
"Somewhere In The Sun" Beachfront Cottage - Old Florida Style Hideaway
10/10 Excellent
"Great beach bungalow. Pictures don’t do it justice. Much more spacious than we anticipated. Had everything we needed. Very cute and wonderful views of the beach. Area was great for us, quiet, private, not touristy at all. We saw so many stars at night, even saw the Milky Way the first night there. Definitely recommend if you are looking for that old school small Florida beach house vibe."
Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes, Tennis, 🐶 friendly
10/10 Excellent
"House was perfict if your looking for a quit place and relaxing time this is your place"
More cheap accommodation in Panacea

The Old Carrabelle Hotel
201 Tallahassee St Carrabelle FL
NZ$207
18 Oct - 19 Oct
includes taxes & fees

The Panacea Motel
1545 Coastal Hwy Panacea FL
NZ$222
6 Oct - 7 Oct
includes taxes & fees

Best Western Wakulla Inn & Suites
3292 Coastal Hwy 98 Crawfordville FL
NZ$230
18 Oct - 19 Oct
includes taxes & fees
8.8/10 Excellent! (1,001 reviews)

The Moorings Hotel and Marina
1000 Hwy 98 Carrabelle FL
NZ$253
12 Oct - 13 Oct
includes taxes & fees
8.6/10 Excellent! (54 reviews)

Cozy Waterfront 'island House' on Live Oak Island!
Crawfordville FL
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