A pier extending into calm waters with a small boat docked at the end.

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Our top choices for Panacea hotels

The Panacea Motel

The Panacea Motel
2.0 star property
Panacea
9.0 out of 10, Wonderful, (184 reviews)
"Quiet clean great place to rest."
United States
Elias
The price is NZ$203
includes taxes & fees
8 July - 9 July
The Panacea Motel

Breezy Home w/ Grills, Pool & Beach Access!

Breezy Home w/ Grills, Pool & Beach Access!
3.0 star property
Panacea
Breezy Home w/ Grills, Pool & Beach Access!

The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
3.0 star property
Crawfordville
9.4 out of 10, Exceptional, (1,003 reviews)
"Spotless room, very comfortable beds and good choices on the menu at the restaurant."
United States
Margaret
The price is NZ$189
includes taxes & fees
8 July - 9 July
The Lodge at Wakulla Springs

The Old Carrabelle Hotel

The Old Carrabelle Hotel
2.0 star property
Carrabelle
9.4 out of 10, Exceptional, (35 reviews)
"It was very quiet and centrally located to local restaurants and bars. "
United States
Ricki
The price is NZ$219
includes taxes & fees
9 July - 10 July
The Old Carrabelle Hotel

Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
2.5 star property
Crawfordville
8.8 out of 10, Excellent, (1,003 reviews)
"Very friendly staff. Great overnight stay."
United States
Suzie
The price is NZ$241
includes taxes & fees
9 July - 10 July
Best Western Wakulla Inn & Suites

Franklin Inn

Franklin Inn
2.0 star property
Carrabelle
7.8 out of 10, Good, (496 reviews)
"The AC was very cold working perfectly, and the room was clean."
United States
Sugeil
The price is NZ$182
includes taxes & fees
7 July - 8 July
Franklin Inn

St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
3.5 star property
Carrabelle
9.0 out of 10, Wonderful, (405 reviews)
"Such a great place to stay! Clean, quiet and safe plus the restaurant on site is very good. Will definitely stay again!"
United States
Albert
The price is NZ$389
includes taxes & fees
6 Aug - 7 Aug
St James Bay Golf & Pickleball Resort

Wildwood Inn

Wildwood Inn
3.0 star property
Crawfordville
8.6 out of 10, Excellent, (1,002 reviews)
"Great place!"
United States
Phyllis
The price is NZ$249
includes taxes & fees
19 July - 20 July
Wildwood Inn

The Moorings Hotel and Marina

The Moorings Hotel and Marina
2.5 star property
Carrabelle
8.4 out of 10, Very good, (49 reviews)
"Very clean room!"
United States
Heriberto
The price is NZ$313
includes taxes & fees
9 July - 10 July
The Moorings Hotel and Marina

Waterfront Escape w/ Balcony on Shell Point Beach!

Waterfront Escape w/ Balcony on Shell Point Beach!
3.5 star property
Crawfordville
9.4 out of 10, Exceptional, (3 reviews)
"Quite and peaceful getaway."
United States
Michael
Waterfront Escape w/ Balcony on Shell Point Beach!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Panacea attractions

Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

A sunset over a calm body of water with silhouettes of birds flying and a distant tree line.

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Frequently asked questions

What is the best area to stay in Panacea?
The best area to stay in Panacea is right along the waterfront, particularly around the main highway, US-98.

This area is the heart of Panacea, offering direct access to the Gulf of Mexico's tranquil waters. You'll find most of the local seafood restaurants and shops concentrated along US-98, making it very convenient. It's a relaxed, coastal community known for its fishing and natural beauty.

Families often find this area ideal due to its proximity to the water-based activities. Many accommodations here offer easy access to fishing charters, boat rentals, and paddleboarding opportunities in the bay. The educational exhibits at the Gulf Specimen Marine Lab are also a short walk away, providing an engaging experience for children and adults alike.

Couples looking for a quiet escape will appreciate the peaceful atmosphere and scenic views. The waterfront properties often provide lovely spots to relax and enjoy the sunset over the bay, with several local eateries offering fresh seafood right on the water.
What are the best hotels in Panacea that travellers recommend?
For a highly recommended hotel in Panacea, consider The Panacea Motel.

The Panacea Motel, with a 9.0 rating, offers excellent value and is praised by guests for its comfortable beds and nice towels. It provides free self-parking and early check-in is often available. The motel is conveniently located near local attractions such as Woolley Park, just 1.0 km away, Gulf Specimen Public Aquarium, 1.5 km away, and Panacea Park, which is 1.2 km from the property.
What are the top pet-friendly hotels in Panacea?
For a top pet-friendly hotel in Panacea, consider The Panacea Motel.

The Panacea Motel, with a very good 9.0 rating, is an excellent choice for travellers with pets as both dogs and cats are permitted. Guests frequently mention the good beds and the nice towels, alongside the good value for the price. The hotel also offers early check-in, which can be very convenient. It is well-located near local attractions such as Woolley Park, just 1.0 km away, Gulf Specimen Public Aquarium, 1.5 km away, and Panacea Park, 1.2 km away.
What are the best budget hotels in Panacea?
For a top budget hotel in Panacea, consider The Panacea Motel.

This motel, with a 9.0 rating, is frequently praised by guests for its good value and comfortable beds, with many noting the nice towels provided. It offers free WiFi and complimentary self-parking. Early check-in is also available, which can be very convenient. The Panacea Motel is handily located near local attractions, being only 0.3 km from Panacea Springs, 1.0 km from Woolley Park, and 1.2 km from Panacea Park.
What are the best hotels in Panacea near Woolley Park?
For a highly-rated hotel in Panacea near Woolley Park, consider The Panacea Motel.

The Panacea Motel, with a 9.0 rating, is conveniently located just 1.0 km from Woolley Park. Guests often mention the comfortable beds and the good value for money. The motel also offers free WiFi and complimentary self-parking, and early check-in is available. It is also only 1.5 km from the Gulf Specimen Public Aquarum and 1.2 km from Panacea Park.
When is the best time to go to Panacea?
The best time to go to Panacea, Florida, is typically during the spring (March to May) and autumn (September to November) months.

During these periods, the weather is pleasantly warm, with comfortable temperatures ranging from the low 20s to high 20s Celsius. You'll find fewer crowds compared to the peak summer season, making it ideal for a relaxing and unhurried experience. It's superb for enjoying outdoor activities like kayaking, fishing, or exploring the nature trails without the intense heat and humidity of summer.

Travellers looking for a tranquil escape will appreciate the calm waters and the opportunity to spot local wildlife, such as manatees and various bird species. The mild weather makes it a great time for couples to enjoy romantic walks along the coastline or explore the local seafood restaurants.

Conversely, while summer (June to August) offers very warm weather for swimming, it also brings higher humidity, more frequent thunderstorms, and larger crowds.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, although it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24 to 48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to 'My Trips' and selecting your reservation. To find flexible deals, filter your search by 'Fully refundable property' for hotels in Panacea.
How can I save on a hotel booking in Panacea with Expedia?
One Key™ – Expedia's free travel rewards programme – gives you instant access to perks and Member Prices on Panacea hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Panacea?
Prices for hotels in Panacea often vary, but you can find a great deal from NZ$182 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by 'Price: low to high' for our cheapest rates.

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