A pier extending into calm waters with a small boat docked at the end.

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Check prices for these dates

Tonight
20 Aug - 21 Aug
Tomorrow
21 Aug - 22 Aug
This weekend
21 Aug - 23 Aug
Next weekend
28 Aug - 30 Aug

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Our top choices for Panacea hotels

1. The Panacea Motel

The Panacea Motel
Panacea
United States
Michelle
NZ$210
includes taxes & fees
24 Aug - 25 Aug
The Panacea Motel

2. Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
Crawfordville
United States
Lydia
NZ$194
includes taxes & fees
3 Sept - 4 Sept
Best Western Wakulla Inn & Suites

3. Wildwood Inn

Wildwood Inn
Crawfordville
United States
Megan
NZ$226
includes taxes & fees
8 Sept - 9 Sept
Wildwood Inn

4. The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
Crawfordville
United States
Sherry
NZ$198
includes taxes & fees
24 Aug - 25 Aug
The Lodge at Wakulla Springs

5. St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
Carrabelle
United States
Mike
NZ$310
includes taxes & fees
21 Aug - 22 Aug
St James Bay Golf & Pickleball Resort

6. The Old Carrabelle Hotel

The Old Carrabelle Hotel
Carrabelle
United States
David
NZ$196
includes taxes & fees
1 Sept - 2 Sept
The Old Carrabelle Hotel

7. The Moorings Hotel and Marina

The Moorings Hotel and Marina
Carrabelle
United States
Tina
NZ$316
includes taxes & fees
25 Aug - 26 Aug
The Moorings Hotel and Marina

8. Franklin Inn

Franklin Inn
Carrabelle
United States
Melynda
NZ$159
includes taxes & fees
23 Aug - 24 Aug
Franklin Inn
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Stay near popular Panacea attractions

Alligator Point Beach

8.8/10 (10 reviews)
Escape to this pristine stretch of old coastal Florida with white sands and shallow, clear waters. Spot dolphins and sea turtles while enjoying the serenity of an undeveloped shoreline.
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Bald Point State Park

8.6/10 (20 reviews)
Where Ochlockonee Bay meets Apalachee Bay, this coastal park showcases diverse ecosystems from beaches to pine flatwoods. Spot migrating raptors and monarch butterflies while hiking through pristine natural habitats.
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Mashes Sand Beach

8.8/10 (3 reviews)
Mashes Sands Beach offers serene shallow waters and expansive sandbars perfect for peaceful exploration. Wade through the tea-colored Gulf waters while spotting hermit crabs and enjoying spectacular sunset views.
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Wilson Beach

Wilson Beach offers a serene Gulf Coast escape with pristine shores and gentle waves far from tourist crowds. Bring supplies and enjoy peaceful beachcombing along this unspoiled natural sanctuary.
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Panacea Springs

Once a popular health resort, these historic mineral springs were believed to possess healing properties in the early 1900s. Explore the remnants of spa structures while imagining the therapeutic rituals of a bygone era.
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Public Beach Access

Mashes Sands Beach features tranquil white-sand shores and shallow waters ideal for families. Wade in the gentle surf, cast a fishing line, or enjoy a peaceful picnic away from tourist crowds.
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Gulf Specimen Public Aquarum

Take the children to visit the sea life you'll find at Gulf Specimen Public Aquarum during your holiday to Panacea. Stroll along the beaches in this relaxing area or seek out the fishing spots.
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Panacea Park

After visiting Panacea Park, make a plan to see the other sights and activities in Panacea. Stroll along this relaxing area's beaches or simply enjoy its seafood restaurants.
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Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

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A sunset over a calm body of water with silhouettes of birds flying and a distant tree line.

Top Panacea Hotel Reviews

Recent Reviews in Panacea

Hideaway Beach Cottage on waterfront with amazing views.

Hideaway Beach Cottage on waterfront with amazing views.

10/10 Excellent
"Incredible experience all the way around !Clean, cozy, inviting and stellar communication!!"
Cherie D. 10-night trip
Posted 7 hours ago
Hideaway Beach Cottage on waterfront with amazing views.
Directly on the water, great sunrise and sunset.50% off monthly rate fall/winter

Directly on the water, great sunrise and sunset.50% off monthly rate fall/winter

10/10 Excellent
"The property was amazing. We had a blast."
Anonymous traveller 7-night trip
Posted 5 days ago
Directly on the water, great sunrise and sunset.50% off monthly rate fall/winter
Bayfront/Ocean Views/Shared Boat Dock/Pets

Bayfront/Ocean Views/Shared Boat Dock/Pets

8/10 Good
"Excellent, but it could have been even better! I rated it four stars because there was a foul odor left in the refrigerator by the previous tenant. The cleaning crew should have caught this. Also, there was no gas tank for the gas grill when we arrived. Molly took care of these things quickly once we were able to get through to her. We hope to return someday soon, and look forward to giving this wonderful place a five star review next time."
Phil B. 4-night trip
Posted 5 days ago
Bayfront/Ocean Views/Shared Boat Dock/Pets
Best deal at Alligator Point

Best deal at Alligator Point

10/10 Excellent
"We had a clean, comfy, peaceful stay with a beautiful view!An attentive host! A deck w/ sunset views! Highly Recommend!Thank you for a wonderful stay!"
Lynn P. 3-night trip
Posted 5 days ago
Best deal at Alligator Point
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

10/10 Excellent
"We had an amazing week. Best equipped home we have ever stayed. The privacy and peacefulness was just want we needed. Host was very responsive."
Tracy G. 7-night trip
Posted 5 days ago
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
The Panacea Motel

The Panacea Motel

10/10 Excellent
"I loved the retro feel of the place."
Michelle 1-night trip
Posted 8 days ago
The Panacea Motel
Gulf Breeze – Pet-Friendly 3BR Beachfront Stay with Stunning Views & Renovations

Gulf Breeze – Pet-Friendly 3BR Beachfront Stay with Stunning Views & Renovations

10/10 Excellent
"We’ve spent many years on Alligator Point, and this has to be our new favorite house to stay in. The guys fished from under the house most of the time. It was a wonderful trip!!"
Jessica H. 7-night trip
Posted 12 days ago
Gulf Breeze – Pet-Friendly 3BR Beachfront Stay with Stunning Views & Renovations
Happy Shack BEACH & BAY! Kayak, paddle boards, tiki hut, firepit, grille, wifi

Happy Shack BEACH & BAY! Kayak, paddle boards, tiki hut, firepit, grille, wifi

10/10 Excellent
"I just want to express my deepest gratitude for allowing us to stay in your beautiful home. From the moment we arrived, it brought such a sense of peace, calm, and relaxation — exactly what our family needed.Being able to paddleboard alongside the dolphins was absolutely incredible. It felt like we were in our own little world, surrounded by so much beauty and tranquility. The breathtaking sunrises, sunsets, and the precious quality time we shared together are memories we will cherish forever.Thank you again from the bottom of our hearts for opening your home to us and creating such a special place where we could reconnect, unwind, and enjoy every moment. We truly enjoyed our stay and are so grateful for this amazing experience."
Sabrina P. 4-night trip
Posted 2 weeks ago
Happy Shack BEACH & BAY! Kayak, paddle boards, tiki hut, firepit, grille, wifi
5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

10/10 Excellent
"Everyone had great time, house was very nice and accommodating for the whole family. Beds were very comfortable. Would definitely recommend mosquito spray though. Screened porch was a big plus for sitting outside at night. Overall a very peaceful place."
Carolynn G. 3-night trip
Posted 3 weeks ago
5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

More cheap accommodation in Panacea

Franklin Inn

Franklin Inn

1589 US-98 Carrabelle FL
NZ$159
23 Aug - 24 Aug
includes taxes & fees
7.8/10 Good! (504 reviews)
Franklin Inn
Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites

3292 Coastal Hwy 98 Crawfordville FL
NZ$194
3 Sept - 4 Sept
includes taxes & fees
Best Western Wakulla Inn & Suites
The Old Carrabelle Hotel

The Old Carrabelle Hotel

201 Tallahassee St Carrabelle FL
NZ$196
1 Sept - 2 Sept
includes taxes & fees
9.6/10 Exceptional! (43 reviews)
The Old Carrabelle Hotel
The Panacea Motel

The Panacea Motel

1545 Coastal Hwy Panacea FL
NZ$210
24 Aug - 25 Aug
includes taxes & fees
9/10 Wonderful! (188 reviews)
The Panacea Motel
The Moorings Hotel and Marina

The Moorings Hotel and Marina

1000 Hwy 98 Carrabelle FL
NZ$316
25 Aug - 26 Aug
includes taxes & fees
The Moorings Hotel and Marina
Cozy Waterfront 'island House' on Live Oak Island!

Cozy Waterfront 'island House' on Live Oak Island!

Crawfordville FL
Get ratesCozy Waterfront 'island House' on Live Oak Island!

Frequently asked questions

What is the best area to stay in Panacea?
The best area to stay in Panacea is right along the waterfront, particularly around the main highway, US-98.This area is the heart of Panacea, offering direct access to the Gulf of Mexico's tranquil waters. You'll find most of the local seafood restaurants and shops concentrated along US-98, making it very convenient. It's a relaxed, coastal community known for its fishing and natural beauty.Families often find this area ideal due to its proximity to the water-based activities. Many accommodations here offer easy access to fishing charters, boat rentals, and paddleboarding opportunities in the bay. The educational exhibits at the Gulf Specimen Marine Lab are also a short walk away, providing an engaging experience for children and adults alike.Couples looking for a quiet escape will appreciate the peaceful atmosphere and scenic views. The waterfront properties often provide lovely spots to relax and enjoy the sunset over the bay, with several local eateries offering fresh seafood right on the water.
What are the best hotels in Panacea that travellers recommend?
For a highly recommended hotel in Panacea, consider The Panacea Motel.The Panacea Motel, with a 9.0 rating, offers excellent value and is praised by guests for its comfortable beds and nice towels. It provides free self-parking and early check-in is often available. The motel is conveniently located near local attractions such as Woolley Park, just 1.0 km away, Gulf Specimen Public Aquarium, 1.5 km away, and Panacea Park, which is 1.2 km from the property.
What are the top pet-friendly hotels in Panacea?
For a top pet-friendly hotel in Panacea, consider The Panacea Motel.The Panacea Motel, with a very good 9.0 rating, is an excellent choice for travellers with pets as both dogs and cats are permitted. Guests frequently mention the good beds and the nice towels, alongside the good value for the price. The hotel also offers early check-in, which can be very convenient. It is well-located near local attractions such as Woolley Park, just 1.0 km away, Gulf Specimen Public Aquarium, 1.5 km away, and Panacea Park, 1.2 km away.
What are the best budget hotels in Panacea?
For a top budget hotel in Panacea, consider The Panacea Motel.This motel, with a 9.0 rating, is frequently praised by guests for its good value and comfortable beds, with many noting the nice towels provided. It offers free WiFi and complimentary self-parking. Early check-in is also available, which can be very convenient. The Panacea Motel is handily located near local attractions, being only 0.3 km from Panacea Springs, 1.0 km from Woolley Park, and 1.2 km from Panacea Park.
What are the best hotels in Panacea near Woolley Park?
For a highly-rated hotel in Panacea near Woolley Park, consider The Panacea Motel.The Panacea Motel, with a 9.0 rating, is conveniently located just 1.0 km from Woolley Park. Guests often mention the comfortable beds and the good value for money. The motel also offers free WiFi and complimentary self-parking, and early check-in is available. It is also only 1.5 km from the Gulf Specimen Public Aquarum and 1.2 km from Panacea Park.
When is the best time to go to Panacea?
The best time to go to Panacea, Florida, is typically during the spring (March to May) and autumn (September to November) months.During these periods, the weather is pleasantly warm, with comfortable temperatures ranging from the low 20s to high 20s Celsius. You'll find fewer crowds compared to the peak summer season, making it ideal for a relaxing and unhurried experience. It's superb for enjoying outdoor activities like kayaking, fishing, or exploring the nature trails without the intense heat and humidity of summer.Travellers looking for a tranquil escape will appreciate the calm waters and the opportunity to spot local wildlife, such as manatees and various bird species. The mild weather makes it a great time for couples to enjoy romantic walks along the coastline or explore the local seafood restaurants.Conversely, while summer (June to August) offers very warm weather for swimming, it also brings higher humidity, more frequent thunderstorms, and larger crowds.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, although it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24 to 48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to 'My Trips' and selecting your reservation. To find flexible deals, filter your search by 'Fully refundable property' for hotels in Panacea.
How can I save on a hotel booking in Panacea with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Panacea hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Panacea?
Prices for hotels in Panacea often vary, but you can find a great deal from NZ$159 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by 'Price: low to high' for our cheapest rates.

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