Search Panacea hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
20 Nov - 21 Nov
Tomorrow
21 Nov - 22 Nov
This weekend
21 Nov - 23 Nov
Next weekend
28 Nov - 30 Nov

Filter by

Guest rating
Guest rating
Star rating

Top hotels and accommodation in Panacea

Exterior
The Panacea Motel

The Panacea Motel

2.0 star property
Panacea
9.0 out of 10, Wonderful, (132)
"A v nice place to stay "
United States
Harry
The Panacea Motel
Reception
The Lodge at Wakulla Springs

The Lodge at Wakulla Springs

3.0 star property
Crawfordville
9.4 out of 10, Exceptional, (1003)
"Everything about our stay was great! Location, The Lodge, Staff, The food was excellent, and the staff. We only stayed one night as a halfway trip to Disney, but we will definitely be back because our family loved it so much!"
United States
Kaitlyn
The Lodge at Wakulla Springs
Fireplace
Wildwood Inn

Wildwood Inn

3.0 star property
Crawfordville
8.6 out of 10, Excellent, (1003)
"Clean, friendly staff, good location. "
United States
Jennifer
The price is NZ$233
includes taxes & fees
21 Dec - 22 Dec
Wildwood Inn
Dining
Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites

2.5 star property
Crawfordville
8.8 out of 10, Excellent, (944)
"Great hotel. Very good customer service and very clean"
United States
claudina
The price is NZ$240
includes taxes & fees
18 Dec - 19 Dec
Best Western Wakulla Inn & Suites
Exterior
The Moorings Hotel and Marina

The Moorings Hotel and Marina

2.5 star property
Carrabelle
8.4 out of 10, Very good, (39)
"Hotel was really nice and convenient to everything we wanted to do in the area. Very quiet and peaceful. Bed was a little uncomfortable, but that's a personal preference thing and I won't fault them for that. Really nice staff and easy check in and check out. Would definitely return!"
United States
Cheryl
The price is NZ$269
includes taxes & fees
1 Dec - 2 Dec
The Moorings Hotel and Marina
Outdoor pool
St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort

3.5 star property
Carrabelle
9.0 out of 10, Wonderful, (365)
"The facility and amenities were wonderful! Everyone was so friendly and helpful. Our pup enjoyed his stay also. We will be back for sure! "
United States
Amy
The price is NZ$254
includes taxes & fees
23 Nov - 24 Nov
St James Bay Golf & Pickleball Resort
Suite, Courtyard View | Bathroom
The Old Carrabelle Hotel

The Old Carrabelle Hotel

2.0 star property
Carrabelle
The price is NZ$278
includes taxes & fees
23 Nov - 24 Nov
The Old Carrabelle Hotel
Free WiFi, bed sheets
Franklin Inn

Franklin Inn

2.0 star property
Carrabelle
7.8 out of 10, Good, (451)
"JJ was great great location clean room comfortable bed and good value. "
United States
Crystal
The price is NZ$157
includes taxes & fees
2 Dec - 3 Dec
Franklin Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Black Friday Sale

Save up to 40% on select hotels
Book now
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Panacea attractions

Alligator Point Beach

3.5/5 (2 reviews)
Why not spend a lazy afternoon at Alligator Point Beach during your trip to Alligator Point?
See properties

Bald Point State Park

4.6/5 (9 reviews)
You can take time to visit Bald Point State Park during your travels to Alligator Point. Stroll along the beaches in this relaxing area or seek out the fishing spots.
See properties

Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

See all hotels in Panacea
Sunset over a lake at Panacea, northern Florida, USA | NONE |

Top Panacea Hotel Reviews

Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.

Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.

10/10 Excellent
"Host was very hospitable, quick to respond. and very accommodating. Great views, clean home, amenities are exactly what were advertised. Great theme for a home in a beautiful relaxing area on the gulf. Highly recommend "
Jordan C. 4-night trip
Posted 10 days ago
Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.

More cheap accommodation in Panacea

Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites

3292 Coastal Hwy 98 Crawfordville FL
The price is NZ$240 per night from 18 Dec to 19 Dec
NZ$240
18 Dec - 19 Dec
includes taxes & fees
8.6/10 Excellent! (942 reviews)

Frequently asked questions

Where is the best place to stay in Panacea?
Expedia customers give high marks to The Panacea Motel. See all available top hotels, or vacation rentals in Panacea.
What are some of the best holiday rentals that Panacea has to offer?
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front: This highly rated holiday home rental in Panacea is located on the beach, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 7 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You can relax into your holiday with a garden and a selection of games. Other favourite homes for rent in Panacea are NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property! and Coastal Getaway on canal-steps to the beach. See all vacation rentals in Panacea.
If I need to cancel my hotel reservation in Panacea, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.
What's the best dog-friendly place to stay in Panacea?
The Panacea Motel is a top dog-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.
What are some accommodation options with pools in Panacea?
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front: Offers complimentary wireless Internet access, a pool and kitchens. View all hotels with pools in Panacea.
How is it to stay in Panacea?
Nature enthusiasts will enjoy exploring Panacea, and many visitors will definitely appreciate the beaches and seafood restaurants. The relaxing and secluded setting also entices those visiting the city. In Panacea, there are 216 hotels and other accommodation options to choose from. Find out more about Panacea.
What are the top places to visit in Panacea?
Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach and Bald Point State Park. Dolphin viewing is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your itinerary are Wilson Beach and Public Beach Access. Take a look at what more there is to see and do in Expedia's Panacea guide.
What's the seasonal weather in Panacea?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. The rainiest months in Panacea are August, July, June and September, with each month seeing an average of 201 mm of rainfall.

Explore a world of travel with Expedia