Top Hotels Near Florida Keys National Marine Sanctuary in Key West from NZ$345

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Our top choices for Florida Keys National Marine Sanctuary hotels

Queen Deluxe ADA
Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
10.0 out of 10, Exceptional, (1001)
"Very nice & peaceful with a wonderful staff. Our second time staying here"
United States
Sandra
The price is NZ$438
includes taxes & fees
17 Dec - 18 Dec
Almond Tree Inn Hotel - Adults Only
Veranda Room | Terrace/patio
The Conch House Heritage Inn

The Conch House Heritage Inn

The Conch House Heritage Inn
3.5 star property
Old Town Key West, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (144)
"Fantastic location "
United States
ANDREW
The price is NZ$372
includes taxes & fees
18 Dec - 19 Dec
The Conch House Heritage Inn
Property grounds
Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1002)
"Staff awesome, good breakfast great location"
United States
Carin helen
The price is NZ$411
includes taxes & fees
17 Dec - 18 Dec
Orchid Key Inn - Adults Only
Exterior
The Marquesa Hotel

The Marquesa Hotel

The Marquesa Hotel
3.5 star property
Historic Seaport, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1001)
"Perfect place to stay. "
United States
Paulette
The price is NZ$928
includes taxes & fees
17 Dec - 18 Dec
The Marquesa Hotel
11 Gecko's Garden - Adults Only
Tropical Inn

Tropical Inn

Tropical Inn
3.5 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (363)
"The place was excellent and the service amazing "
United States
Janae
The price is NZ$375
includes taxes & fees
17 Dec - 18 Dec
Tropical Inn
Premium bedding, iron/ironing board, free WiFi, bed sheets
Weatherstation Inn

Weatherstation Inn

Weatherstation Inn
2.5 star property
Truman Annex, 0.6 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (995)
"Wonderful property safe neighborhood convenient to all activities would stay here again."
United States
William
The price is NZ$386
includes taxes & fees
18 Dec - 19 Dec
Weatherstation Inn
Front of property
L'Habitation Guest House

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Historic Seaport, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (922)
"Great place close to all. Manager was very helpful in recommending how to get around the island, what to do and where to eat."
United States
Robert
The price is NZ$454
includes taxes & fees
21 Dec - 22 Dec
L'Habitation Guest House
Property grounds
Duval House

Duval House

Duval House
3.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1010)
"I loved this place the location was absolutely perfect "
United States
Frank
The price is NZ$345
includes taxes & fees
18 Dec - 19 Dec
Duval House
Outdoor pool, open 8:00 AM to 10:00 PM, pool loungers
Ella's Cottages - Key West Historic Inns

Ella's Cottages - Key West Historic Inns

Ella's Cottages - Key West Historic Inns
3.5 star property
Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (408)
"The cottage was perfect, centrally located and a wonderful place to stay!"
United States
Claudia
The price is NZ$530
includes taxes & fees
17 Dec - 18 Dec
Ella's Cottages - Key West Historic Inns
Outdoor pool
Silver Palms Inn

Silver Palms Inn

Silver Palms Inn
3.5 star property
Old Town Key West, 1.3 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1024)
"We had a wonderful stay and it was a convenient location for all the activities along Duval Street. The room was clean & comfortable with a great breakfast."
United States
Susanne
The price is NZ$376
includes taxes & fees
18 Dec - 19 Dec
Silver Palms Inn
Front of property – evening/night
Southernmost House

Southernmost House

Southernmost House
4.0 star property
Uptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1002)
"Great place to stay. Staff was very friendly"
United States
Jacob
The price is NZ$684
includes taxes & fees
17 Dec - 18 Dec
Southernmost House
Property grounds
Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1004)
"Cozy place right near everything "
United States
Joseph
Paradise Inn Key West - Adults Only
Outdoor pool
The Key West Hotel

The Key West Hotel

The Key West Hotel
2.5 star property
Historic Seaport, 0.9 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (514)
"location was great nice bar party vibe"
United States
Robert Howard
The price is NZ$524
includes taxes & fees
17 Dec - 18 Dec
The Key West Hotel
Outdoor pool, pool loungers
Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1006)
"Great stay."
United States
Sarit
The price is NZ$945
includes taxes & fees
17 Dec - 18 Dec
Ocean Key Resort - A Noble House Resort
Porch
Heron House - Adult Only

Heron House - Adult Only

Heron House - Adult Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.0 out of 10, Wonderful, (1137)
"Loved the setup of the hotel and great location! "
United States
Rachel
The price is NZ$704
includes taxes & fees
4 Jan - 5 Jan 2026
Heron House - Adult Only
Exterior
Ridley House - Key West Historic Inns

Ridley House - Key West Historic Inns

Ridley House - Key West Historic Inns
3.5 star property
Historic Seaport, 1.1 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (857)
"Room was clean, staff were awesome."
United States
Bridget
The price is NZ$570
includes taxes & fees
17 Dec - 18 Dec
Ridley House - Key West Historic Inns
Exterior
Lighthouse Hotel - Key West Historic Inns

Lighthouse Hotel - Key West Historic Inns

Lighthouse Hotel - Key West Historic Inns
3.5 star property
Bahama Village, 0.6 km from Florida Keys National Marine Sanctuary
9.0 out of 10, Wonderful, (847)
"Great location. Near great food and entertainment."
United States
David
The price is NZ$488
includes taxes & fees
17 Dec - 18 Dec
Lighthouse Hotel - Key West Historic Inns
Front of property
Winslow's Bungalows - Key West Historic Inns

Winslow's Bungalows - Key West Historic Inns

Winslow's Bungalows - Key West Historic Inns
4.0 star property
Old Town Key West, 1.2 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1074)
"Beautiful property, nice clean bungalows and great staff!"
United States
Robert
The price is NZ$530
includes taxes & fees
17 Dec - 18 Dec
Winslow's Bungalows - Key West Historic Inns
Outdoor spa tub
Seascape Tropical Inn - Adult Exclusive

Seascape Tropical Inn - Adult Exclusive

Seascape Tropical Inn - Adult Exclusive
3.0 star property
Downtown Key West, 0.7 km from Florida Keys National Marine Sanctuary
9.0 out of 10, Wonderful, (404)
"Room was spotless and the front desk was excellent. I would stay with them again."
United States
Dave
The price is NZ$807
includes taxes & fees
11 Jan - 12 Jan 2026
Seascape Tropical Inn - Adult Exclusive
Food and drink
The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only
3.0 star property
Downtown Key West, 0.7 km from Florida Keys National Marine Sanctuary
8.8 out of 10, Excellent, (1005)
"Nice place "
United States
Suzanne
The Cabana Inn Key West - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Florida Keys National Marine Sanctuary Hotel Reviews

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

10/10 Excellent
"Beach and pool - bar, music and great staff"
Robert 6-night trip
Posted 1 day ago
Southernmost Beach Resort and Guesthouses

Hotels near other Florida Keys National Marine Sanctuary attractions

Florida Keys Eco - Discovery Center which includes interior views

Florida Keys Eco - Discovery Center

4.3/5 (128 reviews)
Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.
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Fort Zachary Taylor Park, Key West. State Park in Florida, USA., Shutterstock ID 761867707, Purchase Order: SP-1891 Wave 0, Client/Licensee: Hotels.com

Fort Zachary Taylor Historic State Park

4.4/5 (1,160 reviews)
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
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Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, cycling and lively festivals. If you're looking for a convenient place to stay, take a look at the 1604 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Florida Keys National Marine Sanctuary?
Adjacent to Florida Keys National Marine Sanctuary, Caribbean House is one of the top choices for your stay based on our traveller data, and this B&B offers free breakfast and private balconies. Other good choices close by include Southernmost Beach Resort and Guesthouses and La Concha Key West, Autograph Collection.
How many hotels will I find near Florida Keys National Marine Sanctuary?
Expedia has 1604 hotels and other accommodation options within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals near Florida Keys National Marine Sanctuary.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum and Audubon House and Tropical Gardens are some of the notable landmarks to see in the area. You can watch performances at Key West Film Society, Red Barn Theater and Waterfront Playhouse if you're interested in local theatre.

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