Apartments in Defiance

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Check prices for these dates

Next weekend
22 Aug - 24 Aug
In two weeks
29 Aug - 31 Aug
In one month
12 Sept - 14 Sept
In two months
10 Oct - 12 Oct

Featured Apartments in Defiance

Overlook Main St. in this 2 Bedroom Owners Suite!
Fridge, microwave, oven, stovetop

Overlook Main St. in this 2 Bedroom Owners Suite!

4.0 star property
9.4 out of 10, Exceptional, (32)
"Perfect place for a visit to St Charles! Hope to return and stay here again!"
Overlook Main St. in this 2 Bedroom Owners Suite!
Prime Loft of Main Street
Smart TV

Prime Loft of Main Street

9.8 out of 10, Exceptional, (95)
"The apartment had everything we needed for a quick getaway with family. Cute place and perfectly located. "
The price is NZ$420
includes taxes & fees
25 Aug - 26 Aug
Prime Loft of Main Street
Studio on Historic Main by StayLage
1 bedroom, iron/ironing board, WiFi, bed sheets

Studio on Historic Main by StayLage

9.4 out of 10, Exceptional, (27)
"Loved the studio apartment. did not know there were over 20 steps up to apartment. Also did not get much sleep on the weekend nights due to bar right across the street and no window insulation. Would add some decaf options for coffee/tea. Would add a bath mat for when you get out of shower. would add a rubber mat for tub/shower because it is slippery. But overall loved the apartment!"
The price is NZ$357
includes taxes & fees
25 Aug - 26 Aug
Studio on Historic Main by StayLage
The Hidden Gem - 2BR Basement Apartment on 7 Acres
Fridge, microwave, oven, stovetop

The Hidden Gem - 2BR Basement Apartment on 7 Acres

10.0 out of 10, Exceptional, (11)
"Another great stay at The Hidden Gem. Easy access in a quiet location!"
The price is NZ$463
includes taxes & fees
2 Sept - 3 Sept
The Hidden Gem - 2BR Basement Apartment on 7 Acres
The Wild West Getaway- 204-1
2 bedrooms, iron/ironing board, travel cot, WiFi

The Wild West Getaway- 204-1

7.8 out of 10, Good, (7)
"Just make sure you are fit and able to navigate steps. Great party place for the younger generation. The bar below has a nice back outside sitting area we were able to use. "
The Wild West Getaway- 204-1
The Lofts of North Main Street
Dining

The Lofts of North Main Street

9.6 out of 10, Exceptional, (144)
"Perfect location!"
The price is NZ$420
includes taxes & fees
25 Aug - 26 Aug
The Lofts of North Main Street
Remodeled Kirkwood Guest house
Smart TV

Remodeled Kirkwood Guest house

10.0 out of 10, Exceptional, (74)
"Great location and place to stay!"
Remodeled Kirkwood Guest house
Amazing Renovated Historic Loft on Main Street
Fridge, microwave, oven, stovetop

Amazing Renovated Historic Loft on Main Street

10.0 out of 10, Exceptional, (53)
"The place was great, just as advertised. Location was close to everything and made for a nice weekend away from kids"
The price is NZ$420
includes taxes & fees
25 Aug - 26 Aug
Amazing Renovated Historic Loft on Main Street
The Historic Bricks on Main
TV

The Historic Bricks on Main

9.6 out of 10, Exceptional, (10)
"Love how close it is to everything. Very clean. Would stay there again. "
The price is NZ$399
includes taxes & fees
17 Aug - 18 Aug
The Historic Bricks on Main
Augusta Studio at Halcyon Spa Bed & Breakfast
Property grounds

Augusta Studio at Halcyon Spa Bed & Breakfast

10.0 out of 10, Exceptional, (31)
"Our stay was perfect. It was very convenient being downtown Augusta and being able to catch a trolley to the wineries. I would highly recommend this stay."
Augusta Studio at Halcyon Spa Bed & Breakfast
‘The Merlot Bungalow’ Defiance Tiny Home on Trail
Dining

‘The Merlot Bungalow’ Defiance Tiny Home on Trail

10.0 out of 10, Exceptional, (3)
"We loved our stay and will be telling our friends!"
‘The Merlot Bungalow’ Defiance Tiny Home on Trail
Swim, Fish, Hike, Horseback
Outdoor dining

Swim, Fish, Hike, Horseback

9.6 out of 10, Exceptional, (60)
"We were in town for a wedding and this property was wonderful for us all to stary together. The owners were very friendlt and had so much knowledge to share with us of the area and their property. 10/10 reccomend staying here!"
Swim, Fish, Hike, Horseback
Cozy Clark Suite in Frenchtown Saint Charles
Smart TV

Cozy Clark Suite in Frenchtown Saint Charles

9.2 out of 10, Wonderful, (7)
Cozy Clark Suite in Frenchtown Saint Charles
Private Basement Retreat w/ HOT TUB by StayLage
TV

Private Basement Retreat w/ HOT TUB by StayLage

9.0 out of 10, Wonderful, (7)
"My husband could not say enough about his stay. We not only recommend this place but will stay there again. Great communication and a beautiful space!"
The price is NZ$404
includes taxes & fees
17 Aug - 18 Aug
Private Basement Retreat w/ HOT TUB by StayLage
Charming Duplex on Main
Fridge, microwave, stovetop, toaster

Charming Duplex on Main

10.0 out of 10, Exceptional, (13)
"Everything was awesome!!!!!!"
The price is NZ$461
includes taxes & fees
18 Aug - 19 Aug
Charming Duplex on Main
Zia New Haven
Shaman Suite | Living room

Zia New Haven

3.5 star property
9.8 out of 10, Exceptional, (8)
"The property was well kept up and the owners provided everything you could need for a comfortable stay. Laura is very sweet and made us feel very welcome for our 25th wedding anniversary. I highly recommend staying here. The town is small but it is only a short distance to wineries, distilleries and many other things of interest. "
Zia New Haven
Back Door Guest Suite, charming downtown area, 2 minute walk to Missouri River.
Smart TV, books

Back Door Guest Suite, charming downtown area, 2 minute walk to Missouri River.

10.0 out of 10, Exceptional, (4)
"Beautiful relaxing place in adorable neighborhood! Quite the find!"
The price is NZ$421
includes taxes & fees
9 Sept - 10 Sept
Back Door Guest Suite, charming downtown area, 2 minute walk to Missouri River.
1st Capitol Mansion - Suite 401
Private kitchen

1st Capitol Mansion - Suite 401

8.4 out of 10, Very good, (7)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
The price is NZ$395
includes taxes & fees
14 Aug - 15 Aug
1st Capitol Mansion - Suite 401
Spacious 2-Bedroom Near Main St by StayLage
Fridge, microwave, oven, stovetop

Spacious 2-Bedroom Near Main St by StayLage

8.8 out of 10, Excellent, (13)
"We are grateful for our comfortable stay, and the location felt safe as well as close to everything."
Spacious 2-Bedroom Near Main St by StayLage
Great for Business Travelers! Pool + Gym
Pool

Great for Business Travelers! Pool + Gym

The price is NZ$311
includes taxes & fees
25 Aug - 26 Aug
Great for Business Travelers! Pool + Gym
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"Clean. Quiet. Nice. "
Brittani 1-night trip
Posted 2 days ago
Ameristar Casino Resort and Spa

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your holiday.
Why would you choose apartments instead of traditional hotels?
An apartment is often more spacious than a traditional hotel room and comes with a kitchen, so you can cook some of your meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want to stay away from the tourist areas.
What's the top apartment I should consider for a stay in Defiance?
Here's a top apartment in the area to consider: 'the Ruebling House': Bright, Modern, & Renovated!: Located 0.1 mi/0.2 km away in Defiance .
How many apartments will I find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather in Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you are planning a longer stay in Defiance. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. Otherwise, look for flights into Lambert-St. Louis International Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, consider renting a car to explore more sights.