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Top hotels and accommodation in Defiance

The Wildwood Hotel

3.5 star property
9.2 out of 10, Wonderful, (1559)
"Great location for our stay"
The Wildwood Hotel

Drury Inn & Suites St. Louis St. Peters

3.0 star property
9.2 out of 10, Wonderful, (1011)
"Great stay and awesome continental breakfast too!"
The price is NZ$204
includes taxes & fees
17 Aug - 18 Aug
Drury Inn & Suites St. Louis St. Peters

Comfort Inn & Suites St. Louis - O'Fallon

2.5 star property
7.6 out of 10, Good, (1006)
"Very clean and quite stay."
The price is NZ$176
includes taxes & fees
27 July - 28 July
Comfort Inn & Suites St. Louis - O'Fallon

Super 8 by Wyndham St. Clair MO

2.0 star property
7.2 out of 10, Good, (875)
"I would stay here again. "
The price is NZ$105
includes taxes & fees
22 Aug - 23 Aug
Super 8 by Wyndham St. Clair MO

Sleep Inn & Suites O'Fallon MO - Technology Drive

2.5 star property
8.8 out of 10, Excellent, (1013)
"Good place to stay"
The price is NZ$174
includes taxes & fees
27 July - 28 July
Sleep Inn & Suites O'Fallon MO - Technology Drive

Drury Plaza Hotel St. Louis Creve Coeur

3.0 star property
9.2 out of 10, Wonderful, (1003)
"Great environment, friendly staff, and clean spacious rooms."
The price is NZ$237
includes taxes & fees
3 Aug - 4 Aug
Drury Plaza Hotel St. Louis Creve Coeur

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

2.5 star property
9.2 out of 10, Wonderful, (917)
"Great place to stay. Felt safe and secure there"
The price is NZ$208
includes taxes & fees
22 Aug - 23 Aug
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Drury Inn & Suites Southwest St. Louis

3.0 star property
9.4 out of 10, Exceptional, (1010)
"Always a great stay"
The price is NZ$222
includes taxes & fees
10 Aug - 11 Aug
Drury Inn & Suites Southwest St. Louis

Super 8 by Wyndham Eureka/Six Flags Nearby

2.0 star property
7.0 out of 10, Good, (1004)
"The room was clean and cool when we arrived. We really enjoyed our stay!"
The price is NZ$128
includes taxes & fees
3 Aug - 4 Aug
Super 8 by Wyndham Eureka/Six Flags Nearby

Super 8 by Wyndham Union

2.0 star property
8.2 out of 10, Very good, (601)
"Staff was nice,rooms were clean,and hotel was clean "
The price is NZ$151
includes taxes & fees
31 July - 1 Aug
Super 8 by Wyndham Union

Super 8 by Wyndham Washington

2.0 star property
8.4 out of 10, Very good, (658)
"Very clean rooms, friendly staff, great parking!"
The price is NZ$170
includes taxes & fees
31 July - 1 Aug
Super 8 by Wyndham Washington

Courtyard by Marriott St. Louis Chesterfield

3.0 star property
9.0 out of 10, Wonderful, (540)
"Close to several food choices "
The price is NZ$214
includes taxes & fees
22 Aug - 23 Aug
Courtyard by Marriott St. Louis Chesterfield

Comfort Suites St Charles - St Louis

2.5 star property
8.6 out of 10, Excellent, (981)
"Nice place to stay."
The price is NZ$186
includes taxes & fees
27 July - 28 July
Comfort Suites St Charles - St Louis

Holiday Inn Express & Suites St Peters by IHG

2.5 star property
9.2 out of 10, Wonderful, (326)
"Spacious, clean room with a huge bathroom... definitely will stay here again "
The price is NZ$171
includes taxes & fees
10 Aug - 11 Aug
Holiday Inn Express & Suites St Peters by IHG

Wingate by Wyndham St. Louis/Fenton Route 66

3.0 star property
8.2 out of 10, Very good, (1026)
"Decent hotel for its price!"
The price is NZ$170
includes taxes & fees
27 July - 28 July
Wingate by Wyndham St. Louis/Fenton Route 66

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
8.4 out of 10, Very good, (1027)
"Great place to stay and staff are nice, kind, and helpful. "
The price is NZ$180
includes taxes & fees
3 Aug - 4 Aug
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Hampton Inn St. Louis/Chesterfield

3.5 star property
8.6 out of 10, Excellent, (1005)
"Great place to stay"
The price is NZ$189
includes taxes & fees
23 Aug - 24 Aug
Hampton Inn St. Louis/Chesterfield

Drury Plaza Hotel St. Louis St. Charles

3.0 star property
9.6 out of 10, Exceptional, (1017)
"It was a very enjoyable stay."
The price is NZ$211
includes taxes & fees
17 Aug - 18 Aug
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis Chesterfield

3.0 star property
9.6 out of 10, Exceptional, (1016)
"Hotel staff was very nice and helpful and the location is great to be near nice areas for shopping."
The price is NZ$249
includes taxes & fees
29 July - 30 July
Drury Plaza Hotel St. Louis Chesterfield

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
9.4 out of 10, Exceptional, (1015)
"Great location, loved the staff, so nice and helpful. "
The price is NZ$200
includes taxes & fees
27 July - 28 July
Country Inn & Suites by Radisson, St. Charles Historic District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near top Defiance attractions

Learn more about Defiance

Trip time! Discover the wineries, parks and history in Defiance.

Top Defiance Hotel Reviews

Frequently asked questions

What's the best place to stay in Defiance?

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Hollywood Casino & Hotel St. Louis and Days Inn and Suites by Wyndham St. Louis/Westport Plaza. See all available top hotels, or vacation rentals in Defiance.

What are some of the best holiday rentals that Defiance has to offer?

Stunning 1890's Home - Sleeps 8! : This holiday home rental outside of Defiance has air conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Defiance.

If I need to cancel my hotel reservation in Defiance, will I receive a refund?

Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.

What are some accommodation options with pools in Defiance?
How is it staying in Defiance?

Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium and Gateway Arch. In Defiance, there are 20 hotels and other accommodation options to choose from. Find out more about Defiance.

What should I do while I'm visiting Defiance?

Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. A couple of additional sights to add to your itinerary are Yellow Farmhouse Winery and Chandler Hill Vineyards. Take a look at what more there is to see and do in Expedia's Defiance guide.

What's the weather like in Defiance?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.