A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Check prices for these dates

This weekend
10 Jul - 12 Jul
Next weekend
17 Jul - 19 Jul

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Our top choices for Defiance hotels

Indoor pool

Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.6 out of 10, Good, (1,005 reviews)
"Excellent place to stay!"
United States
Steven
The price is NZ$155
includes taxes & fees
14 July - 15 July
Baymont by Wyndham Warrenton
Lobby

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (1,004 reviews)
"Staff was helpful, area was easy tp navigate. Place was great for the price"
United States
Ryan
The price is NZ$166
includes taxes & fees
13 July - 14 July
Quality Inn Foristell
Reception

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
7.8 out of 10, Good, (1,412 reviews)
"Will definitely stay again!"
United States
Trevor
The price is NZ$191
includes taxes & fees
8 July - 9 July
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Standard Room, 1 Queen Bed

Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton
2.0 star property
Warrenton
7.4 out of 10, Good, (663 reviews)
"Terrific staff very helpful manager"
United States
Dale
The price is NZ$128
includes taxes & fees
12 July - 13 July
Super 8 by Wyndham Warrenton
Lobby

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
Wentzville
6.4 out of 10, (549 reviews)
"Room was clean but basic"
United States
James
The price is NZ$139
includes taxes & fees
22 July - 23 July
Economy Inn Wentzville
Premium bedding, desk, iron/ironing board, free WiFi

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,044 reviews)
"We enjoyed our stay. The staff was very nice and the hotel was well kept and clean."
United States
Patrice
The price is NZ$173
includes taxes & fees
13 July - 14 July
Sleep Inn & Suites O'Fallon MO - Technology Drive
Room, 2 Queen Beds, Non Smoking

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
7.8 out of 10, Good, (1,270 reviews)
"nice place"
United States
diana
The price is NZ$170
includes taxes & fees
8 July - 9 July
Wingate by Wyndham St. Louis/Fenton Route 66
Free daily buffet breakfast

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.2 out of 10, Wonderful, (366 reviews)
"Was a good place to stay"
Canada
Blake
The price is NZ$193
includes taxes & fees
12 July - 13 July
Best Western Plus Fenton
Indoor pool

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,006 reviews)
"Good staff "
United States
Solomon
The price is NZ$197
includes taxes & fees
19 July - 20 July
Hampton Inn St. Charles St. Peters
Exterior

Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
St. Peters
9.4 out of 10, Exceptional, (423 reviews)
"Great stay. Easy and quick check in."
United States
John
The price is NZ$214
includes taxes & fees
19 July - 20 July
Holiday Inn Express & Suites St Peters by IHG
Front of property – evening/night

Cedar Creek

Cedar Creek
3.0 star property
New Haven
9.0 out of 10, Wonderful, (271 reviews)
"Nice quiet stay for nearby wedding. "
United States
joan
The price is NZ$271
includes taxes & fees
28 July - 29 July
Cedar Creek
Lobby

Quality Inn Near Six Flags St. Louis

Quality Inn Near Six Flags St. Louis
2.5 star property
Pacific
8.4 out of 10, Very good, (389 reviews)
"Great last minute booking when we needed to get off the road after a long day."
United States
Brent
The price is NZ$227
includes taxes & fees
12 July - 13 July
Quality Inn Near Six Flags St. Louis
Lobby

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.0 out of 10, Wonderful, (704 reviews)
"Very clean and staff were friendly. Breakfast was good and will definitely stay here again. "
United States
Rod
The price is NZ$257
includes taxes & fees
12 July - 13 July
Best Western Plus Washington Hotel
Room, 2 Queen Beds, Non Smoking

Super 8 by Wyndham Washington

Super 8 by Wyndham Washington
2.0 star property
Washington
8.4 out of 10, Very good, (734 reviews)
"This was a very good place to stay with our dogs. Clean, comfortable, accessible, with friendly staff."
United States
Lisa
The price is NZ$172
includes taxes & fees
20 July - 21 July
Super 8 by Wyndham Washington
Lobby

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.4 out of 10, Exceptional, (1,006 reviews)
"Great location and clean hotel!"
United States
Admir
The price is NZ$221
includes taxes & fees
2 Aug - 3 Aug
Drury Inn & Suites St. Louis St. Peters
Family Studio Suite (No Elevator Access)

River Sirens Hotel

River Sirens Hotel
2.5 star property
Washington
9.8 out of 10, Exceptional, (205 reviews)
"We love the theme, the hotel was clean and we love that we could walk down to the alley and play arcade games and have a beer and we love the breakfast voucher as well. What a neat place to stay."
United States
Natalie
The price is NZ$268
includes taxes & fees
12 July - 13 July
River Sirens Hotel
In-room safe, desk, laptop workspace, blackout curtains

TownePlace Suites by Marriott Wentzville

TownePlace Suites by Marriott Wentzville
3.0 star property
Wentzville
9.4 out of 10, Exceptional, (56 reviews)
"Room was excellent, staff very nice "
United States
Amy
The price is NZ$349
includes taxes & fees
31 July - 1 Aug
TownePlace Suites by Marriott Wentzville
Iron/ironing board, free WiFi, bed sheets, alarm clocks

Americas Best Inn - Eureka

Americas Best Inn - Eureka
2.5 star property
Eureka
6.4 out of 10, (148 reviews)
"Good Stay"
United States
Brianna
The price is NZ$149
includes taxes & fees
8 July - 9 July
Americas Best Inn - Eureka
Exterior

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
8.4 out of 10, Very good, (190 reviews)
"The location was great"
United States
DeLante
The price is NZ$161
includes taxes & fees
2 Aug - 3 Aug
WoodSpring Suites St Peters-OFallon
43-inch LED TV with digital channels, TV

Comfort Inn & Suites St. Louis - O'Fallon

Comfort Inn & Suites St. Louis - O'Fallon
2.5 star property
O'Fallon
7.6 out of 10, Good, (1,003 reviews)
"I was very comfortable. Great green spaces for my little dog. Breakfast was okay."
United States
Louise
The price is NZ$153
includes taxes & fees
28 July - 29 July
Comfort Inn & Suites St. Louis - O'Fallon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

A glass of red wine on a wooden table with a vineyard in the background.
Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

7.8/10 (7 reviews)
This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
See properties

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Top Defiance Hotel Reviews

Recent Reviews in Defiance

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"Check-in was a 10/10 they were very nice even aloud us to check-in early.walked us through everything from the start of breakfast to where we should park, my family and I really enjoyed our stay and we will book again 🤗"
Melissa 3-night trip
Posted 2 hours ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

More cheap accommodation in Defiance

Motel 6 Maryland Heights, MO

Motel 6 Maryland Heights, MO

12330 Dorsett Rd Maryland Heights MO
The price is NZ$132 per night from 8 July to 9 July
NZ$132
8 July - 9 July
includes taxes & fees
6.2/10 (1,003 reviews)

Frequently asked questions

What's the best place to stay in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Hollywood Casino & Hotel St. Louis and The Wildwood Hotel. See all available top hotels, or vacation rentals in Defiance.
What are some of the best holiday rentals that Defiance has to offer?
🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟: This holiday home rental outside of Defiance offers a patio, a garden and air conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool and buffet. The Wildwood Hotel and Hilton St. Louis Frontenac are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium and Gateway Arch. In Defiance, there are 19 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
The picturesque setting of August A. Busch Memorial Conservation Area and Missouri River exemplify the area's natural beauty. A couple of additional sights to add to your itinerary are Chandler Hill Vineyards and Sugar Creek Winery. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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