Defiance Hotel & Accommodation Deals 2026 from NZ$139 - Fully Refundable Options

A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Our top choices for Defiance hotels

A hotel room with a bed, a sofa, a coffee table, and wall art.

A Sleep Inn & Suites hotel with a modern brick facade, a covered entrance, and a parking lot.

An indoor swimming pool with a clear view of the outside, a metal ladder, and a ceiling with recessed lighting.

A hotel lobby with a reception desk, seating area, and a large potted plant.

1. Sleep Inn & Suites O'Fallon MO - Technology Drive

O'Fallon

Tim

NZ$163

includes taxes & fees

6 Oct - 7 Oct

A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

A modern hotel room with a desk, chair, and a large mirror.

A Holiday Inn Express hotel with a brick facade, a covered entrance, and a clear sky.

A reception desk with a modern design, featuring a blue geometric wall and a wooden finish.

2. Holiday Inn Express St. Louis West - O'Fallon by IHG

O'Fallon

Greg

NZ$187

includes taxes & fees

11 Oct - 12 Oct

A multi-story hotel with a central entrance featuring a covered patio area.

A hotel room with a sofa, armchair, bedside table, lamp, TV, and a bed with patterned bedding.

A hotel with a swimming pool, outdoor seating, and a covered patio area.

A hotel lobby with a sectional sofa, a fireplace, a flat-screen TV, and framed artwork on the walls.

3. Staybridge Suites O'Fallon Chesterfield by IHG

O'Fallon

Norman

NZ$233

includes taxes & fees

18 Oct - 19 Oct

An outdoor patio area with a stone fire pit, wicker furniture, and a covered seating area with a view of the building's interior.

A hotel room with a sofa, a side table, a lamp, a flat-screen TV, and a bed with a red blanket.

A modern kitchen with wooden cabinets, a stainless steel countertop, and various appliances including a coffee maker and a rice cooker.

A multi-story hotel with a brick facade, a covered outdoor seating area with a fire feature, and a sign indicating it is a Marriott property.

4. TownePlace Suites by Marriott St. Louis Chesterfield

Chesterfield

Bobbi jo

NZ$268

includes taxes & fees

12 Oct - 13 Oct

A hotel with a prominent tower, a fountain in the courtyard, and a well-maintained garden.

A hotel room with a large bed, a bedside lamp, a telephone, a mirror, and a bathroom with a sink and towel rack.

A modern bathroom with a large mirror, white vanity, and a bathtub.

A formal dining table set for six with a vase of white flowers, candles, and a view of buildings through large windows.

5. The Wildwood Hotel

Wildwood

Ryan

NZ$172

includes taxes & fees

2 Nov - 3 Nov

A spacious lobby with a stone fireplace, seating area, and a bar with high stools.

A hotel lobby with a seating area featuring two armchairs, a round coffee table, and a flat-screen TV mounted on a wooden wall.

A hotel pantry stocked with beverages and snacks, a refrigerated display case, and a sign reading "The Market".

A modern living room with a fireplace, a flat-screen TV, a sofa, a coffee table, and a dining area.

6. Residence Inn by Marriott O'Fallon

O'Fallon

Gerald

NZ$275

includes taxes & fees

18 Oct - 19 Oct

A modern dining area with a brick fireplace, yellow and blue chairs, and a blue sofa.

A picnic area with a table and benches, surrounded by grass and trees.

A gym with a treadmill, elliptical, stationary bike, and a rack of dumbbells.

A hotel with a brick facade, multiple parking spaces, and a grassy area in the foreground.

7. Comfort Inn & Suites Chesterfield - St. Louis

Chesterfield

Brenda

NZ$181

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a high ceiling, a central seating area with sofas and a coffee table, and a large window providing natural light.

A spacious lobby with a fireplace, comfortable seating, a large painting, and a view of the kitchen area.

A shop with a variety of snacks and beverages, including a refrigerated section with drinks and a display of packaged snacks.

A hotel with a covered entrance, multiple flags, and a well-maintained lawn.

8. Hilton Garden Inn St. Louis/O'Fallon MO

O'Fallon

Kassie

NZ$229

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio area with wicker furniture and a central fire feature.

A hotel room with a bed, a sofa, a desk, and a chair.

A modern hotel lobby with a bar area, seating arrangements, and a reception desk.

A Courtyard Marriott hotel with a parking lot and a green shuttle service.

9. Courtyard by Marriott St. Louis Chesterfield

Chesterfield

Kelly

NZ$250

includes taxes & fees

11 Oct - 12 Oct

Two people in a swimming pool with colorful inflatable rings.

A buffet counter with a variety of food items, including pastries and beverages, and a person serving.

A spacious lobby with a stone fireplace, a chandelier, and a staircase.

A hotel room with a large bed, a desk, a TV, and a view of a pool through the glass door.

10. Holiday Inn St. Louis West Six Flags by IHG

Eureka

Rob

NZ$245

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a central round table, two sofas, and a chandelier.

A hotel room with two beds, a patterned wall, and a view of the city through sheer curtains.

An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

A Drury Plaza hotel with a modern design, featuring a curved facade, large windows, and a Drury Plaza sign on the top.

11. Drury Plaza Hotel St. Louis Chesterfield

Chesterfield

Parvaneh Pattie

NZ$269

includes taxes & fees

11 Oct - 12 Oct

A modern kitchen area with a breakfast bar, a coffee machine, and a refrigerator displaying menu options.

A coffee station with two coffee machines and a display of coffee pods and cups.

A hotel room with two beds, a blue sofa, a small table, and a kitchenette.

A pool area with a blue pool lift chair, a pool user capacity sign, and a tiled wall.

12. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Chesterfield

Terry

NZ$236

includes taxes & fees

11 Oct - 12 Oct

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.

A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract painting on the wall.

A hotel room with three computer workstations, each with a monitor, keyboard, and a lamp.

13. Hyatt Place St. Louis/Chesterfield

Chesterfield

Shane

NZ$249

includes taxes & fees

18 Oct - 19 Oct

A courtyard with a central seating area, surrounded by trees and a building with a pitched roof.

A modern dining area with a long table, multiple chairs, and pendant lighting.

A reception desk with a "WELCOME TO THE SHOW ME STATE" sign, a wooden counter, and a Hilton Honors sign.

A store interior with a 'Treats' sign, snack shelves, and a chalkboard with a welcome message.

14. Hampton Inn & Suites St. Louis/Chesterfield

Chesterfield

Vijay

NZ$236

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio with a built-in grill, seating area, and stone walls.

A spacious lounge area with a stone fireplace, comfortable seating, and a large TV screen.

A multi-story hotel with a parking lot in front.

A modern lobby with a stone accent wall, a flat-screen TV, a reception desk, seating area with sofas and ottomans, and a patterned rug.

15. Residence Inn by Marriott St. Louis Chesterfield

Chesterfield

Chelsea

NZ$394

includes taxes & fees

11 Oct - 12 Oct

A modern hotel with a prominent entrance, a landscaped courtyard, and a well-lit facade.

A modern conference room with a large table, four chairs, a computer, and a bookshelf with books and a framed picture.

An outdoor patio area with a stone wall, seating, and a table.

A hotel room with two beds, a desk, a chair, and a TV.

16. AC Hotel by Marriott St. Louis Chesterfield

Chesterfield

Richard

NZ$328

includes taxes & fees

11 Oct - 12 Oct

An indoor swimming pool with a hot tub, clear signage, and a view of the outside through large windows.

A modern dining area with yellow and blue chairs, a flat-screen TV, and a kitchen area with appliances.

A spacious living area with a blue wall, yellow armchairs, a blue sofa, and a wooden coffee table.

A modern hotel room with a grey sofa, a wooden coffee table, a flat-screen TV, a wooden dresser, and a large window with curtains.

17. Comfort Inn Near Six Flags St. Louis

Pacific

Gail

NZ$198

includes taxes & fees

26 Oct - 27 Oct

A spacious lobby with a high ceiling, a dining area, and a kitchen in the background.

A modern hotel lobby with a computer desk, a flat-screen TV, and a ceiling fan.

A lobby with a checkered carpet, a marble coffee table, two armchairs with patterned cushions, a sofa, and a dining table with chairs.

A hotel room with a bathroom, a bed, a nightstand, and a window.

18. Quality Inn Near Six Flags St. Louis

Pacific

Rachel

NZ$198

includes taxes & fees

26 Oct - 27 Oct

A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows allowing natural light.

A modern hotel room with a neatly made bed, a bedside table with a lamp, a wall-mounted artwork, and a small seating area with a bench.

An indoor swimming pool with a clear water area, a shallow end, and a tiled deck surrounding the pool. There are lounge chairs and tables on the deck, and a sign indicating a maximum capacity of 62.

A Hampton Inn with a brick facade, outdoor seating area, and a clear sky.

19. Hampton Inn St. Louis Wentzville

Wentzville

Jill

NZ$282

includes taxes & fees

11 Oct - 12 Oct

A spacious living room with a large painting, a fireplace, a staircase, and modern furniture.

A swimming pool with tiled edges and a hot tub area, surrounded by windows and chairs.

A hotel room with a large bed, two sofas, a desk, and a TV.

An outdoor patio with a beige sofa set, two armchairs, and a table.

20. Best Western Plus Washington Hotel

Washington

Shawn

NZ$262

includes taxes & fees

11 Oct - 12 Oct

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Stay near popular Defiance attractions

A glass of red wine on a wooden table with a vineyard in the background.

Chandler Hill Vineyards

7.8/10 (7 reviews)

This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.

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A wooden dock extending into a pond with lily pads, surrounded by lush greenery and a clear blue sky.

August A. Busch Memorial Conservation Area

8.6/10 (7 reviews)

This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.

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Sugar Creek Winery

8.0/10 (1 review)

Sip award-winning Missouri wines at this hillside vineyard along the scenic Katy Trail. Relax on covered decks with your own picnic while enjoying live weekend music and panoramic countryside views.

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Historic Daniel Boone Home and Heritage Center

9.6/10 (4 reviews)

Step into the limestone home where Daniel Boone's son Nathan crafted a frontier masterpiece with seven fireplaces. Explore the surrounding historic village for an authentic glimpse into 19th-century pioneer life.

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Broemmelsiek Park

This 494-acre natural playground offers nine miles of trails through forests and around serene lakes. Attend a monthly stargazing event at the astronomy viewing area for a uniquely celestial park experience.

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Yellow Farmhouse Winery

This boutique winery in Defiance, Missouri was known for its distinctive unfiltered wines and relaxed atmosphere. Visitors could enjoy tastings with live music while picnicking on scenic grounds with vineyard views.

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Matson Hill Park Trailhead

Wander through 475 acres of rugged forest terrain with challenging hiking paths and gravity-flow mountain bike trails. The historic 1830s Hays Home offers a glimpse into pioneer life amid the natural splendour.

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Hamburg Trail Trailhead

This moderate 6.9-mile loop winds through the scenic Weldon Spring Conservation Area, connecting to the Katy Trail State Park. Spot native wildlife while traversing diverse landscapes of shaded woodlands and open fields.

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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance

Top Defiance Hotel Reviews

Recent Reviews in Defiance

Hyatt Place St. Louis/Chesterfield

8/10 Good

"The staff was very helpful to working out a problem with my reservation"

Drury Plaza Hotel St. Louis St. Charles

10/10 Excellent

"The evening snacks and morning breakfast were excellent; the staff was friendly and responsive."

Sonesta ES Suites St. Louis - Chesterfield

10/10 Excellent

"The only complaint is out dead bolt got stuck so it was hard to close our door"

The Wildwood Hotel

8/10 Good

"Room was clean, yet picures and description are a bit deceiving. Overall, stay was good and would come back again."

Ameristar Casino Resort and Spa

10/10 Excellent

"Easy parking, friendly staff, and large rooms were the highlights of Ameristar. I picked this hotel for my last night in St. Louis before a depressingly early flight. At 10 minutes to the airport, it was a very easy morning. The casino was an added bonus, giving me a way to unwind before my time home. Unfortunately, it is extremely smoky from the moment you get off the elevator from the parking garage. Even on the non-smoking floor of the casino, there is no refuge from the cigarette smell. That was to be expected though, and my non-smoking room was clean and unexpectedly large with a sunken living room and view of a body of water that I'm too lazy to look up."

Wingate by Wyndham St. Louis/Fenton Route 66

10/10 Excellent

"Good channel sel"

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

10/10 Excellent

"Clean and quiet place to walk from a concert at the theater. No drinking and driving"

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

8/10 Good

"It’s a former Drury Inn property so it’s built well and pretty quiet. Room was clean and comfortable. A bit on the small size but not cramped."

Studio 6 Extended Stay - St Louis, MO - Westport/Craig Road

8/10 Good

"Hotel is in a safe, convenient location. NO elevator, but there was an entrance with no steps on the first level. The hallway is a little grody but the room was very clean and arranged in a very convenient way. Lots of space to set things out to organize. Full kitchen but no utensils or cooking pans or dishes. I suppose they would be stolen if they were provided. I did not need them anyway. No ice machine, but ice trays to make your own ice in the freezer. Nice TV with lots of channels. Comfortable bed but lumpy pillow. Nice shower and bathroom. Basically it was perfect for my purposes as I was attending a meeting just down the street at a more expensive hotel. Families do live there and there was more noise in the hall than some would probably like. I ignored it. The office does not open until 9 in the morning and I had to be at my meeting before that time on the day of checkout. So, I had to return in the afternoon as I wanted my checkout paper. The staff was very nice and very helpful."

More cheap accommodation in Defiance

Sleep Inn & Suites O'Fallon MO - Technology Drive

1147 Technology Drive O'Fallon MO

NZ$163

6 Oct - 7 Oct

includes taxes & fees

9/10 Wonderful! (1,132 reviews)

Quality Inn Foristell

12 Highway W Foristell MO

NZ$168

3 Nov - 4 Nov

includes taxes & fees

Country Inn & Suites by Radisson, St. Peters, MO

3877 Veterans Memorial Pkwy St. Charles MO

NZ$174

1 Nov - 2 Nov

includes taxes & fees

8/10 Very good! (1,002 reviews)

Comfort Suites St Charles - St Louis

1400 S 5th St St. Charles MO

NZ$197

1 Nov - 2 Nov

includes taxes & fees

Hampton Inn St. Charles St. Peters

3720 W Clay St St. Charles MO

NZ$243

25 Oct - 26 Oct

includes taxes & fees

Country Inn & Suites by Radisson, St. Charles Historic District

1190 S Main St St. Charles MO

NZ$272

1 Nov - 2 Nov

includes taxes & fees

Frequently asked questions

What is the best area to stay in Defiance?

The best area to stay in Defiance is directly within the village centre, particularly near the intersection of Highway F and Femme Osage Creek Road.This area is the heart of Defiance, offering a collection of local businesses, dining options, and access to the Katy Trail. It's a small, walkable village with a relaxed pace, surrounded by scenic vineyards and rolling hills. The historic Defiance Roadhouse is a popular landmark here.For couples looking for a romantic getaway, the village centre is ideal. You'll find boutique accommodation options, often with a focus on local wines and cuisine. It's great for enjoying leisurely meals, exploring the nearby wineries, and taking peaceful walks along the Katy Trail.Solo travellers seeking a peaceful retreat and outdoor activities will also find the village centre appealing.

When is the best time to go to Defiance?

The best times to go to Defiance are during the spring (late April to early June) and autumn (September to October) when the weather is pleasant and the natural beauty of the area is at its peak.Spring offers mild temperatures, making it ideal for outdoor activities like cycling and hiking along the Katy Trail. The vineyards begin to bud, and the countryside is lush and green. This period is particularly good for couples who enjoy scenic walks and wine tasting without the summer crowds.Autumn brings cooler, crisp air and the stunning transformation of the leaves, creating a picturesque backdrop for exploring the region. Many local wineries also host harvest festivals during this time. For those who appreciate outdoor beauty and a relaxed pace, this season provides an excellent experience.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, although it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24 to 48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to 'My Trips' and selecting your reservation. To find flexible deals, filter your search by 'Fully refundable property' for hotels in Defiance.

How can I save on a hotel booking in Defiance with Expedia?

One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Defiance hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

How much is the nightly rate for a hotel in Defiance?

Prices for hotels in Defiance often vary, but you can find a great deal from NZ$139 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by 'Price: low to high' for our cheapest rates.

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Activities in Town and Country

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Search Defiance hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Defiance

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Defiance hotels

1. Sleep Inn & Suites O'Fallon MO - Technology Drive

2. Holiday Inn Express St. Louis West - O'Fallon by IHG

3. Staybridge Suites O'Fallon Chesterfield by IHG

4. TownePlace Suites by Marriott St. Louis Chesterfield

5. The Wildwood Hotel

6. Residence Inn by Marriott O'Fallon

7. Comfort Inn & Suites Chesterfield - St. Louis

8. Hilton Garden Inn St. Louis/O'Fallon MO

9. Courtyard by Marriott St. Louis Chesterfield

10. Holiday Inn St. Louis West Six Flags by IHG

11. Drury Plaza Hotel St. Louis Chesterfield

12. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

13. Hyatt Place St. Louis/Chesterfield

14. Hampton Inn & Suites St. Louis/Chesterfield

15. Residence Inn by Marriott St. Louis Chesterfield

16. AC Hotel by Marriott St. Louis Chesterfield

17. Comfort Inn Near Six Flags St. Louis

18. Quality Inn Near Six Flags St. Louis

19. Hampton Inn St. Louis Wentzville

20. Best Western Plus Washington Hotel

Stay near popular Defiance attractions

Chandler Hill Vineyards

August A. Busch Memorial Conservation Area

Sugar Creek Winery

Historic Daniel Boone Home and Heritage Center

Broemmelsiek Park

Yellow Farmhouse Winery

Matson Hill Park Trailhead

Hamburg Trail Trailhead

Learn more about Defiance

Top Defiance Hotel Reviews

Recent Reviews in Defiance

Hyatt Place St. Louis/Chesterfield

Drury Plaza Hotel St. Louis St. Charles

Sonesta ES Suites St. Louis - Chesterfield

The Wildwood Hotel

Ameristar Casino Resort and Spa

Wingate by Wyndham St. Louis/Fenton Route 66

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Studio 6 Extended Stay - St Louis, MO - Westport/Craig Road

More cheap accommodation in Defiance

Sleep Inn & Suites O'Fallon MO - Technology Drive

Quality Inn Foristell

Country Inn & Suites by Radisson, St. Peters, MO

Comfort Suites St Charles - St Louis

Hampton Inn St. Charles St. Peters

Country Inn & Suites by Radisson, St. Charles Historic District

Frequently asked questions

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