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23 Nov - 24 Nov
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Top hotels and accommodation in Defiance

Lobby sitting area
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
Fenton
8.0 out of 10, Very good, (1018)
"Very friendly staff "
United States
Amber
The price is NZ$175
includes taxes & fees
30 Nov - 1 Dec
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Ballroom
The Wildwood Hotel

The Wildwood Hotel

3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1604)
"Great hotel in a great neighborhood "
United States
Linda
The price is NZ$190
includes taxes & fees
24 Nov - 25 Nov
The Wildwood Hotel
Front of property
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

3.0 star property
Chesterfield
8.0 out of 10, Very good, (1025)
"Clean room,Friendly staff, Good location and Good Breakfast options"
United States
Micheal
The price is NZ$192
includes taxes & fees
30 Nov - 1 Dec
Sonesta ES Suites St. Louis - Chesterfield
Property amenity
Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton

2.5 star property
Warrenton
7.4 out of 10, Good, (1000)
"The room was amazing the jacuzzi tub worked great we love our stay at Baymont "
United States
Christopher
The price is NZ$175
includes taxes & fees
30 Nov - 1 Dec
Baymont by Wyndham Warrenton
Lobby
Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport

2.5 star property
Maryland Heights
8.0 out of 10, Very good, (1018)
"Clean rooms, courteous staff, good breakfast. Great stay at a reasonable price. "
United States
Shanna
The price is NZ$205
includes taxes & fees
24 Nov - 25 Nov
Best Western Plus St. Louis West-Westport
Exterior
Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG

2.5 star property
Wentzville
9.4 out of 10, Exceptional, (825)
"Good all around stay "
United States
Chad
The price is NZ$238
includes taxes & fees
12 Dec - 13 Dec
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Exterior
Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG

2.5 star property
O'Fallon
8.6 out of 10, Excellent, (821)
"The staff was so friendly and helpful! The hotel was exceptionally clean. Breakfast was very good with lots of variety!"
United States
Millie
The price is NZ$200
includes taxes & fees
25 Nov - 26 Nov
Holiday Inn Express St. Louis West - O'Fallon by IHG
Lobby
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1001)
"Hotel was very clean."
United States
christine
The price is NZ$238
includes taxes & fees
30 Nov - 1 Dec
Drury Plaza Hotel St. Louis St. Charles
1 bedroom, Egyptian cotton sheets, premium bedding, pillow-top beds
Best Western Plus Washington Hotel

Best Western Plus Washington Hotel

2.5 star property
Washington
9.2 out of 10, Wonderful, (630)
"Would stay again. "
United States
Alisa
The price is NZ$262
includes taxes & fees
24 Nov - 25 Nov
Best Western Plus Washington Hotel
Lobby
Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

2.5 star property
O'Fallon
8.8 out of 10, Excellent, (1004)
"Nice breakfast, friendly staff"
United States
Damon
The price is NZ$187
includes taxes & fees
24 Nov - 25 Nov
Sleep Inn & Suites O'Fallon MO - Technology Drive
Desk, blackout curtains, iron/ironing board, free cots/infant beds
Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66

3.0 star property
Fenton
7.8 out of 10, Good, (1096)
"We’ve stayed here often and love it! "
United States
Joan
The price is NZ$163
includes taxes & fees
30 Nov - 1 Dec
Wingate by Wyndham St. Louis/Fenton Route 66
Front of property – evening/night
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 star property
Maryland Heights
8.4 out of 10, Very good, (2207)
"We had a pleasant stay."
United States
Larry
The price is NZ$186
includes taxes & fees
8 Dec - 9 Dec
Hollywood Casino & Hotel St. Louis
Front of property
Super 8 by Wyndham Eureka/Six Flags Nearby

Super 8 by Wyndham Eureka/Six Flags Nearby

2.0 star property
Eureka
7.0 out of 10, Good, (1004)
"A much needed comfortable bed and hot shower, staff was lovely. "
United States
Rachel
The price is NZ$125
includes taxes & fees
7 Dec - 8 Dec
Super 8 by Wyndham Eureka/Six Flags Nearby
Exterior
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

2.5 star property
St. Charles
8.0 out of 10, Very good, (1005)
"polite staff, great service, nice breakfast, clean room "
United States
John
The price is NZ$179
includes taxes & fees
14 Dec - 15 Dec
Hampton Inn St. Charles St. Peters
In-room safe, desk, laptop workspace, blackout curtains
Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton

2.0 star property
Warrenton
7.4 out of 10, Good, (610)
"I have stayed several times at this hotel, it is always very clean, the staff are super nice and very convenient to I-70; would recommend this hotel and I will definitely stay there again."
United States
Kimberly
The price is NZ$129
includes taxes & fees
21 Dec - 22 Dec
Super 8 by Wyndham Warrenton
Lobby
Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles

2.0 star property
St. Peters
6.4 out of 10, (1001)
"Staff was very friendly. Room was kept clean."
United States
Sandra
The price is NZ$127
includes taxes & fees
8 Dec - 9 Dec
Days Inn by Wyndham St Peters/St Charles
Lobby
AC Hotel by Marriott St. Louis Chesterfield

AC Hotel by Marriott St. Louis Chesterfield

3.5 star property
Chesterfield
9.2 out of 10, Wonderful, (229)
"Newer hotel, very clean, up to date and in nice area. "
United States
Johnny
The price is NZ$246
includes taxes & fees
27 Nov - 28 Nov
AC Hotel by Marriott St. Louis Chesterfield
Daily buffet breakfast (USD 12.95 per person)
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3.0 star property
Chesterfield
8.2 out of 10, Very good, (781)
"Just a really nice hotel tucked away from everything, but still close to get whereevre you need to go!"
United States
Roy
The price is NZ$202
includes taxes & fees
30 Nov - 1 Dec
Hilton Garden Inn Chesterfield
Premium bedding, desk, iron/ironing board, free cots/infant beds
Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles

2.0 star property
St. Charles
8.0 out of 10, Very good, (1002)
"I'd stay at this place again. "
United States
Suzanne
The price is NZ$155
includes taxes & fees
21 Dec - 22 Dec
Super 8 by Wyndham St Charles
Exterior
Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Holiday Inn Express & Suites St. Louis West - Fenton by IHG

3.0 star property
Fenton
8.8 out of 10, Excellent, (1004)
"Spotless room great mattress and pillows and super friendly staff"
United States
judith
The price is NZ$196
includes taxes & fees
3 Dec - 4 Dec
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Missouri wineries have some of the most superb wine we've ever tasted! We recommend sipping on some chambourcin while basking in the sunshine.
Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

You can enjoy a tasting or tour at Chandler Hill Vineyards during your travels to Defiance. While in this romantic area, you can savour the top-notch restaurants.
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Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

August A. Busch Memorial Conservation Area

Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savour the top-notch restaurants.
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

10/10 Excellent
"Great service - quaint location"
Kim 1-night trip
Posted 1 day ago
Country Inn & Suites by Radisson, St. Charles Historic District

More cheap accommodation in Defiance

Relax Inn Saint Charles

Relax Inn Saint Charles

3800 Harry S Truman Blvd St. Charles MO
The price is NZ$125 per night from 26 Nov to 27 Nov
NZ$125
26 Nov - 27 Nov
includes taxes & fees
6.4/10 (1,001 reviews)

Frequently asked questions

What's the best place to stay in Defiance?
Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and Hilton St. Louis Frontenac. See all available top hotels, or vacation rentals in Defiance.
What are some of the best holiday rentals that Defiance has to offer?
The St. Charles Guest House, lovely historic home, fun for families and groups: This holiday home rental outside of Defiance is located on a river, and has a fireplace, a selection of games and air conditioning to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. See all vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Offers an indoor pool, an outdoor pool and buffet. Hilton St. Louis Frontenac and La Quinta Inn & Suites by Wyndham St. Louis Westport are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station and Gateway Arch. In Defiance, there are 20 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at Matson Hill Park Trailhead, August A. Busch Memorial Conservation Area and Missouri River. A couple of additional sights to add to your itinerary are Yellow Farmhouse Winery and Chandler Hill Vineyards. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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