All hotels in Southern Illinois, Illinois
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
All hotels in Southern Illinois, Illinois
We have found 994 Southern Illinois Hotels
- Silo Farm Haus- located in the heart of wine country!
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
- Days Inn by Wyndham Paducah
- Best Western St. Louis Airport North Hotel & Suites
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Courtyard by Marriott Cape Girardeau Downtown
- Welcome Suites Hazelwood
- Baymont by Wyndham Litchfield
- Red Roof Inn Paducah
- Drury Inn & Suites Cape Girardeau
- Comfort Suites Jackson-Cape Girardeau
- Best Western Premier Alton-St. Louis Area Hotel
- Hampton Inn St. Louis Southwest
- Baymont by Wyndham Tuscola
- Embassy Suites by Hilton St. Louis Airport
- Hampton Inn Cape Girardeau I 55 East
- Travelodge by Wyndham Terre Haute
- SpringHill Suites by Marriott Terre Haute
- Hampton Inn Paris
- New Harmony Inn Resort and Conference Center
Let Expedia take you to the best Hotels in Southern Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.