All hotels in Southern Illinois, Illinois
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
All hotels in Southern Illinois, Illinois
We have found 940 Southern Illinois Hotels
- The Westin St. Louis
- La Quinta Inn & Suites by Wyndham Terre Haute
- Drury Inn & Suites St. Louis Forest Park
- St. Louis Airport Hotel
- Drury Inn & Suites Terre Haute
- Drury Inn & Suites St. Louis Creve Coeur
- Holiday Inn Express & Suites St. Louis West - Fenton, an IHG Hotel
- Hilton St. Louis Frontenac
- SpringHill Suites St. Louis Brentwood
- Best Western St. Louis Airport North Hotel & Suites
- Courtyard by Marriott St. Louis Brentwood
- Holiday Inn St Louis SW - Route 66, an IHG Hotel
- Red Roof Inn Paducah
- The Charles F. Knight Center
- Courtyard by Marriott St Louis Creve Coeur
- Drury Inn & Suites Paducah
- Hotel Indigo St. Louis - Downtown, an IHG Hotel
- Drury Inn & Suites Sikeston, MO
- Hampton Inn Terre Haute
- The West End
- Terre Haute Casino Resort
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
- Silo Farm Haus- located in the heart of wine country!
- MainStay Suites St. Louis - Galleria
- Mustang Inn
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Baymont by Wyndham Tuscola
- SureStay Plus by Best Western Fenton
- Baymont by Wyndham Litchfield
- Courtyard by Marriott Cape Girardeau Downtown
Let Expedia take you to the best Hotels in Southern Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.