All hotels in Southern Illinois, Illinois
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
All hotels in Southern Illinois, Illinois
We have found 1155 Southern Illinois Hotels
- Drury Inn & Suites St. Louis Fairview Heights
- Drury Inn & Suites Marion
- Drury Plaza Hotel Mt. Vernon
- Drury Inn & Suites St. Louis O'Fallon, IL
- Super 8 by Wyndham O'Fallon
- Comfort Suites Mount Vernon
- Best Western Delta Inn
- Quality Inn O'Fallon IL - St. Louis
- Americas Best Value Inn Collinsville St. Louis
- Comfort Suites Fairview Heights - St. Louis
- Red Lion Inn & Suites Pontoon Beach
- Holiday Inn Express Metropolis by IHG
- Super 8 by Wyndham Troy IL/St. Louis Area
- Country Inn & Suites by Radisson, Fairview Heights, IL
- Baymont by Wyndham Marion
- Seasons Inn & Suites Highland
- Unique Suites Hotel
- Drury Inn & Suites St. Louis Collinsville
- Holiday Inn Express & Suites Mount Vernon by IHG
- Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
- Quality Inn & Suites near St. Louis and I-255
- Country Hearth Inn & Suites Edwardsville St. Louis
- Red Roof Inn St Louis - Troy, IL
- Sleep Inn O'Fallon near I-64
- Walker's Bluff Casino Resort
- Holiday Inn Express & Suites Effingham by IHG
- Days Inn by Wyndham Collinsville/St. Louis
- La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
- Baymont by Wyndham Effingham
- Baymont by Wyndham O'Fallon St. Louis Area
- Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
- Super 8 by Wyndham Carbondale
- Best Western Plus MidAmerica Hotel
- Best Western Plus Pontoon Beach
- Quality Inn And Suites
- Welcome Suites
- Super 8 by Wyndham Fairview Heights-St. Louis
- Holiday Inn Express & Suites Edwardsville by IHG
- Best Western Marion Hotel
- Fairfield Inn & Suites by Marriott O'Fallon, IL
- Fairgrounds Inn
- DoubleTree by Hilton Mt. Vernon
- Econo Lodge & Suites Granite City
- La Quinta Inn & Suites by Wyndham Effingham
- Comfort Inn & Suites O'Fallon - St. Louis Area
- Holiday Inn Carbondale-Conference Center by IHG
- La Quinta Inn & Suites by Wyndham Pontoon Beach
- Home2 Suites by Hilton Carbondale
- Comfort Suites Mattoon East
- Quality Inn & Suites Metropolis I-24
- Best Western Saluki Inn
- Candlewood Suites O Fallon by IHG
- Quality Inn & Suites Caseyville - St. Louis
- Super 8 by Wyndham Mattoon
- Econo Lodge Inn & Suites Fairview Heights - St. Louis
- The Principal Hotel
- Country Inn & Suites by Radisson, Effingham, IL
- Comfort Inn & Suites Marion I-57
- Radisson Hotel Fairview Heights - St. Louis
- Baymont by Wyndham Chester IL
- Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG
- Days Inn by Wyndham Mount Vernon
- Super 8 by Wyndham Mt. Vernon IL
- Hilton Garden Inn St. Louis Shiloh/O'Fallon IL
- Country Inn & Suites by Radisson, Marion, IL
- Quality Inn & Suites Vandalia near I-70 and Hwy 51
- Holiday Inn Express Hotel & Suites Marion Northeast by IHG
- Holiday Inn Express Hotel & Suites Sparta by IHG
- Hampton Inn St. Louis - Columbia
- Red Lion Inn & Suites Caseyville
- Hampton Inn O'Fallon
- Hampton Inn Carbondale
- Hampton Inn & Suites St. Louis-Edwardsville
- Comfort Inn Edwardsville - St. Louis
- University Inn of Carbondale
- Super 8 by Wyndham Marion
- Super 8 by Wyndham Belleville St. Louis Area
- Motel 6 Marion, IL
- Days Inn by Wyndham Salem, Illinois
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Quality Inn & Suites Salem near I-57
- Economy Inn & Suites
- Hilton Garden Inn Mattoon, Il
- Holiday Inn St. Louis Fairview Heights by IHG
- Country View Inn & Suites
- Holiday Inn Effingham by IHG
- Best Western Plus Centralia Hotel & Suites
- Hampton Inn & Suites Effingham
- Best Western Troy Hotel
- Quality Inn Mount Vernon, IL
- Quality Inn Effingham North
- Super 8 by Wyndham Collinsville St. Louis
- Super 8 by Wyndham Metropolis
Let Expedia take you to the best Hotels in Southern Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.