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Top Luxury Eastern Tennessee Hotels

Carnegie Hotel & Spa

1216 W State Of Franklin Rd Johnson City TN

2 hours drive from Great Smoky Mountains National Park

Stay at this spa hotel in Johnson City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the restaurant and the helpful staff in their ...

9.6/10 Exceptional! (1,325 reviews)

Spacious rooms. Handsome decor in the public areas. Very affordable. Nobody builds hotels like this! For the price of plain vanilla you get beautiful sculpture , art , and leather chairs in the lobby anf other spaces including the restaurant where the waiters are young and happy.

Reviewed on 19 Jan 2026

THE TENNESSEAN Hotel

531 Henley Street Knoxville TN

55 min drive from Great Smoky Mountains National Park

Stay at this luxury hotel in Knoxville. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...

9.4/10 Exceptional! (1,005 reviews)

Great location and wonderful staff

Reviewed on 19 Jan 2026

The Read House Hotel

107 West Martin Luther King Blvd Chattanooga TN

4 hours drive from Great Smoky Mountains National Park

Stay at this business-friendly hotel in Chattanooga. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean ...

9.4/10 Exceptional! (2,345 reviews)

The hotel and staff were great! Clean Rooms updated and comfortable. Beautiful lobby and hotel.

Reviewed on 19 Jan 2026

See all 25,816 properties in Eastern Tennessee

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.