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Top Luxury Panhandle Plains Hotels

Studio 6 Amarillo, TX – West Medical Center

6801 W Interstate 40 Amarillo TX

4 hours drive from Texas Tech University

Stay at this business-friendly hotel in Amarillo. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the breakfast and the pool in their ...

7.4/10 Good! (1,000 reviews)

The room was absolutely amazing for the price. The bed was so comfortable that I actually overslept and didn't want to leave. I would have loved yo have been able to stay longer and make use of v the gym and the pool. Both looked great. If I am ever in Amarillo again I know where I will be staying. ...

Reviewed on 19 Dec 2025

Spark by Hilton Amarillo East

2301 East I40 Amarillo TX

4 hours drive from Texas Tech University

Stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...

8.8/10 Excellent! (278 reviews)

The A/C was somewhat weak - however, we were able to open a window and the cool fresh air was a nice alternative.

Reviewed on 14 Jan 2026

Hawthorn Suites by Wyndham Lubbock

4435 Marsha Sharp Fwy Lubbock TX

25 min walk from Texas Tech University

Stay at this business-friendly hotel in Lubbock. Enjoy free Wi-Fi, free parking and a fitness centre. Our guests praise the helpful staff and the clean rooms ...

7.8/10 Good! (1,007 reviews)

Loved the breakfast. And enjoyed the room and its cleanlines

Reviewed on 19 Jan 2026

See all 2,261 properties in Panhandle Plains

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.