A bench, a bicycle, and a lake surrounded by trees.

Business Hotels & Resorts in Upstate South Carolina from NZ$138

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Check availability on Upstate South Carolina Business Hotels

Tonight
21 Oct - 22 Oct
Tomorrow
22 Oct - 23 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Upstate South Carolina business-friendly hotels

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.
A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.
A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.
A pool area with lounge chairs and a sign for Best Western Plus.

1. Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites
Greenville
United States
Karyn
NZ$148
includes taxes & fees
1 Nov - 2 Nov
Best Western Plus Greenville I-385 Inn & Suites
A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.
An outdoor patio area with tables and chairs, a covered seating area, and a building in the background labeled "Embassy Suites."
A conference room with a long table, chairs, and a carpeted floor.
Electric vehicle charging stations along a sidewalk with a building in the background.

2. Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center
Greenville
United States
Caitlin
NZ$212
includes taxes & fees
1 Nov - 2 Nov
Embassy Suites Greenville Golf Resort & Conference Center
A modern kitchen with hanging light fixtures and bar seating.
A modern bar area with a central island, bar stools, and overhead lighting.
A hotel patio with outdoor seating, stone pillars, and a modern building in the background.
A modern lobby with a curved reception desk, comfortable seating, and a large wall-mounted TV.

3. DoubleTree by Hilton Greenville Woodruff Road

DoubleTree by Hilton Greenville Woodruff Road
Greenville
United States
Farrah
NZ$222
includes taxes & fees
1 Nov - 2 Nov
DoubleTree by Hilton Greenville Woodruff Road
A hotel with a stone facade, multiple windows, and a sign indicating it's a Wyndham hotel.
A room with a wall-mounted ATM, decorative wall panels, a window with red curtains, and a tiled floor.
A modern hotel lobby with vending machines, a refrigerator, a glass door, and a 'Liquor Beer Wine' sign.
A hotel room with two beds, a desk, a TV, and a window with curtains.

4. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
Greenville
United States
Maclin
NZ$138
includes taxes & fees
5 Nov - 6 Nov
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
An indoor swimming pool with a tiled floor, a covered area, and a seating area with chairs.
A modern restaurant with high ceilings, large windows, and a mix of seating options including booths and tables.
A modern hotel lobby with a wooden cabinet, a flat-screen TV, a sofa, and a table.
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a red accent wall.

5. Drury Inn & Suites Greenville

Drury Inn & Suites Greenville
Greenville
United States
David
NZ$223
includes taxes & fees
2 Nov - 3 Nov
Drury Inn & Suites Greenville
A modern hotel room with a large bed, a desk, and a seating area with chairs and a table.
A hotel room with a large bed, a television on a dresser, a nightstand with a lamp, and a window with curtains.
A hotel pool area with lounge chairs, a flag, and a sunset view.
A cafe with a checkered floor, wooden cabinets, and hanging pendant lights.

6. Hampton Inn Greenville I-385 - Woodruff Rd.

Hampton Inn Greenville I-385 - Woodruff Rd.
Greenville
United States
Joseph
NZ$203
includes taxes & fees
29 Oct - 30 Oct
Hampton Inn Greenville I-385 - Woodruff Rd.
A spacious hotel lobby with a central bar area, seating arrangements, and large windows providing natural light.
A modern kitchen with a central island, bar stools, and built-in shelving.
A modern kitchen with a bar area, a seating area with a sofa and chairs, and a television mounted on the wall.
A hotel room with a bed, desk, chair, TV, and a window with a geometric pattern.

7. Holiday Inn Greenville - Woodruff Road by IHG

Holiday Inn Greenville - Woodruff Road by IHG
Greenville
United States
Rick
NZ$213
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Greenville - Woodruff Road by IHG
A multi-story hotel with a modern design, featuring a prominent 'La Quinta' sign, a parking lot, and a landscaped entrance area.
A modern living room with a fireplace, a flat-screen TV, and comfortable seating.
A modern kitchen with a refrigerator, coffee machine, and various food items.
A La Quinta hotel with a covered outdoor seating area, stone pillars, and a parking lot.

8. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
Greenville
United States
Lissette
NZ$195
includes taxes & fees
25 Oct - 26 Oct
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
A modern living room with a sofa, armchairs, a coffee table, and a patterned rug.
A hotel room with two beds, a desk, a TV, and a large window with curtains.
A spacious hotel lobby with a reception desk, seating area, and a large plant.
A hotel lobby with a reception desk, computers, and a seating area.

9. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Greenville
United States
Taleigha
NZ$186
includes taxes & fees
1 Nov - 2 Nov
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
A spacious lobby with a large beige sofa, a fireplace, and a modern chandelier.
A conference room with rows of chairs, a flat-screen TV, a door, and a carpeted floor.
An outdoor patio area with a fire feature, wicker furniture, and potted plants.
A row of Tesla electric vehicle charging stations.

10. Hilton Garden Inn Greenville

Hilton Garden Inn Greenville
Greenville
United States
Leroy
NZ$194
includes taxes & fees
1 Nov - 2 Nov
Hilton Garden Inn Greenville
View all properties

Top Upstate South Carolina Hotel Reviews

Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

10/10 Excellent
"Great stay"
Rubin 1-night trip
Posted 15 hours ago
Best Western Plus Greenville I-385 Inn & Suites
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

10/10 Excellent
"The room was on the ground level so walked out onto the gorgeous sprawling golf course and the lake and the beautiful pool/hot tub facilites. The location was great for where you meet to start a Clemson tour, however it's completely away from the main part of campus and the town otherwise, so nothing is really walkable from it. That's not a big deal b/c everything is a less than 5-10 min drive and the location is so pretty and peaceful it's worth it. we used the pool and hot tub at 8pm and were the only ones there and it was really lovely. The bed was incredibly hard, which was my only complaint."
Alina 1-night trip
Posted 23 hours ago
Clemson University's James F. Martin Inn
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

8/10 Good
"Had some issues with the room but they were minor. The door was difficult to close and lock without having to lean against the door to lock it. The upper lock was loose (safety issue). The grab bar in shower also needed some tightening. For the price, I thought it would be better. I did enjoy my stay though. Just pointing out a few things that could easily be fixed checking between guests."
Cecelia 4-night trip
Posted 1 day ago
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

10/10 Excellent
"."
FLOYD 1-night trip
Posted 2 days ago
Hyatt Place Greenville/Haywood

Frequently asked questions

How much do business-friendly hotels in Upstate South Carolina cost?
Business-friendly hotels in Upstate South Carolina range between NZ$138 and NZ$223 per night. This means you can reserve a stay with useful amenities like workspaces and conference rooms at a price that won't stretch the budget. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Upstate South Carolina?
Take your pick of 144 business-friendly hotels in Upstate South Carolina. When you need to get down to work, Expedia can help you secure the perfect space with the amenities you want.
What are the top business-friendly motels in Upstate South Carolina?
Expedia's business-friendly motels in Upstate South Carolina come with amenities that make it easy to work and play. One of our favourites is Urban Boutique Hotel, BW Signature Collection in Greenville. Located around 3 kilometres northeast of downtown, complimentary breakfast and free WiFi are among its many conveniences. Another property suited to business guests is Days Inn by Wyndham Greenville. It's approximately 8 kilometres east of the centre of Greenville and features a swimming pool, front desk services and more.Greenville is brimming with awesome attractions to keep you busy! Visit Frankie's Fun Park and Greenville Zoo if you find yourself with some free time.
What is there to do in Upstate South Carolina near my business-friendly hotel?
There are countless things to keep you entertained in Upstate South Carolina. If you're making your way to Greenville, don't miss Greenville Zoo, The Children's Museum of the Upstate and Shoeless Joe Jackson Museum. Packing your suitcases for Spartanburg? Spartanburg Regional History Museum, Wofford College and Converse College are among the best sights in this city.

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