Photo by Visit Greenville, South Carolina
Search Upstate South Carolina hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Upstate South Carolina
Check prices for these dates
Our top choices for Upstate South Carolina hotels
Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (466 reviews)
"Very clean and staff the super kind and friendly 10/10 stay"
Kevin
The price is NZ$170
includes taxes & fees
19 Apr - 20 Apr
Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,138 reviews)
"Clean room and great Breakfast "
Tara
The price is NZ$265
includes taxes & fees
12 Apr - 13 Apr
Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (699 reviews)
"Would stay again breakfast was amazing "
Theresa
The price is NZ$178
includes taxes & fees
12 Apr - 13 Apr
Baymont by Wyndham Easley/Greenville
Baymont by Wyndham Easley/GreenvilleEasley
7.4 out of 10, Good, (797 reviews)
"Fantastic place and staff most accommodating "
Walter
The price is NZ$125
includes taxes & fees
12 Apr - 13 Apr
Days Inn by Wyndham Anderson
Days Inn by Wyndham AndersonAnderson
8.0 out of 10, Very good, (1,005 reviews)
"Awesome place "
Tramaness
The price is NZ$114
includes taxes & fees
12 Apr - 13 Apr
Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (446 reviews)
"We love staying at the Hampton Inn in Greer, SC. The staff is always kind and efficient. The rooms are always clean and comfortable. Great place to stay!"
Dawn
The price is NZ$266
includes taxes & fees
9 Apr - 10 Apr
Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (776 reviews)
"The staff was very friendly, great breakfast and the room was very clean. Great stay. "
susan
The price is NZ$183
includes taxes & fees
19 Apr - 20 Apr
The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (823 reviews)
"Great location, great staff - loved the room! "
Eric
The price is NZ$310
includes taxes & fees
12 Apr - 13 Apr
Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (997 reviews)
"Excellent stay "
Elliott
The price is NZ$291
includes taxes & fees
7 Apr - 8 Apr
Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
9.2 out of 10, Wonderful, (871 reviews)
"Clean room , friendly staff , great location "
Gerad
The price is NZ$179
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Holiday Inn Express Hotel & Suites Spartanburg-North by IHGSpartanburg
8.6 out of 10, Excellent, (892 reviews)
"Clean room, helpful staff. Great breakfast! "
Christine
The price is NZ$177
includes taxes & fees
12 Apr - 13 Apr
Hampton Inn Anderson/ Alliance Business Park
Hampton Inn Anderson/ Alliance Business ParkAnderson
9.2 out of 10, Wonderful, (832 reviews)
"Staff were so helpful , place was clean and food spots near by"
osiry
The price is NZ$221
includes taxes & fees
13 Apr - 14 Apr
Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
9.2 out of 10, Wonderful, (1,439 reviews)
"Everything was great at this hotel "
Karen
The price is NZ$182
includes taxes & fees
12 Apr - 13 Apr
Days Inn by Wyndham Greenville South/Mauldin
Days Inn by Wyndham Greenville South/MauldinMauldin
7.4 out of 10, Good, (679 reviews)
"Staff is kind and the hotel is very clean"
Connie
The price is NZ$133
includes taxes & fees
12 Apr - 13 Apr
Quality Inn Clinton - Laurens I-26
Quality Inn Clinton - Laurens I-26Clinton
7.4 out of 10, Good, (541 reviews)
"Very friendly staff and places to eat close by! "
Burit
The price is NZ$111
includes taxes & fees
4 May - 5 May
Four Points by Sheraton Spartanburg
Four Points by Sheraton SpartanburgSpartanburg
9.4 out of 10, Exceptional, (474 reviews)
"Very nice hotel. Room was very clean and attractive. Gorgeous lobby! Would definitely stay here again. "
Edsel
The price is NZ$232
includes taxes & fees
19 Apr - 20 Apr
Best Western Travelers Rest Greenville
Best Western Travelers Rest GreenvilleTravelers Rest
7.6 out of 10, Good, (1,003 reviews)
"It was very clean. The staff was very friendly."
JEANNETTE
The price is NZ$170
includes taxes & fees
12 Apr - 13 Apr
Hampton Inn & Suites Greenville Airport, SC
Hampton Inn & Suites Greenville Airport, SCGreenville
9.2 out of 10, Wonderful, (1,002 reviews)
"The front desk staff at check in and check out were fantastic! "
Tara
The price is NZ$196
includes taxes & fees
12 Apr - 13 Apr
Fairfield Inn & Suites by Marriott Greenville Simpsonville
Fairfield Inn & Suites by Marriott Greenville SimpsonvilleSimpsonville
9.0 out of 10, Wonderful, (692 reviews)
"Great location, great service, great facility
"
henry
The price is NZ$180
includes taxes & fees
12 Apr - 13 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Upstate South Carolina
Cabin
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (68 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Discovery Island Water Park to Frankie's Fun Park.
Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina
Top Upstate South Carolina Hotel Reviews
Aloft Greenville Downtown
10/10 Excellent
More cheap accommodation in Upstate South Carolina
Urban Boutique Hotel, BW Signature Collection
536 Wade Hampton Blvd Greenville SC
The price is NZ$125 per night from 19 Apr to 20 Apr
NZ$125
19 Apr - 20 Apr
includes taxes & fees
8/10 Very Good! (988 reviews)
Explore a world of travel with Expedia
- Motels in Greenville - Spartanburg
- Resort in Greenville - Spartanburg
- Cabin Rentals in Upstate South Carolina
- Serviced Apartments in Greenville
- Apartments in Greenville
- Farmstay in Greenville
- Condo Rentals in Greenville
- Motels in Greenville
- B&B in Greenville
- Holiday Homes in Greenville
- Cabin Rentals in Taylors
- Romantic Hotels in Greenville - Spartanburg
- Lgbt Welcoming Hotels in Greenville Downtown
- Lgbt Welcoming Hotels in Wade Hampton
- Ski Hotels in Upstate South Carolina
- Romantic Hotels in Greenville
- Pet Friendly Hotels in Greenville
- Spa Hotels in Greenville
- Motel 6 Hotels in Greenville
- Drury Inn & Suites Hotels in Upstate South Carolina
- Belton Hotels
- West End Hotels
- Gray Court Hotels
- Williamston Hotels
- Mauldin Hotels
- Hotels near Bob Jones University
- Duncan Hotels
- Moore Hotels
- Woodside Cotton Mill Village Historic District Hotels
- Travelers Rest Hotels
- Liberty Hotels
- Fountain Inn Hotels
- Hotels near Golden Lanes and Golden Skate
- Greer Hotels
- Hotels near Happy Cow Dairy
- Hotels near Donaldson Center
- Greenville Downtown Hotels
- Wade Hampton Hotels
- Hotels near Haywood Mall
- Pelzer Hotels
- Piedmont Hotels
- Greenville Hotels
- Taylors Hotels
- Easley Hotels
- Hotels near Tyger River Park
- Sans Souci Hotels
- Five Forks Hotels
- Woodruff Hotels
- Hotels near Pebble Creek Golf Course
- Flights to Greenville
- Flights to Simpsonville
- Flights from Welcome
- Flights from Donaldson Center
- Flights from Greenville-Spartanburg Intl.
- Flights from Charlotte (CLT) to Greenville (GMU)
- Flights from Miami (MIA) to Greenville (GMU)
- Flights from Burlington (BTV) to Greenville (GSP)
- Flights from Bartow (BOW) to Greenville (GSP)
- Flights from Rota (ROP) to Greenville (GSP)
- Flights from Wellington (WLG) to Greenville (GSP)
- Flights from Los Angeles (LAX) to Greenville (GSP)
- Flights from Wyndham (WYN) to Greenville (GSP)
- Flights from Mason City (MCW) to Greenville (GSP)
- Flights from Atlanta (ATL) to Greenville (GSP)
- Flights from Houston (IAH) to Greenville (GSP)
- Flights from Philadelphia (PHL) to Greenville (GSP)
- Flights from Fort Lauderdale (FLL) to Greenville (GSP)
- Flights from Bari (BRI) to Greenville (GSP)
- Flights from Islamabad (ISB) to Greenville (GSP)
- Flights from Foggia (FOG) to Greenville (GSP)
- Flights from Roi Et (ROI) to Greenville (GSP)
- Flights from Casablanca (CMN) to Greenville (GDC)
- Flights from Clemson (CEU) to Greenville (GDC)
- Flights from Rome (FCO) to Greenville (GDC)
- Flights from Geneva (GVA) to Greenville (GDC)
- Flights from Pickens (LQK) to Greenville (GDC)
- Visit Pelzer
- Visit Hampton-Pinckney Historic District
- Visit Greenville
- Visit Greenville - Spartanburg
- Visit Greenville Downtown
- Visit Five Forks
- Greenville Little Theater
- Butler Springs Park
- Prisma Health Greenville Memorial Hospital
- Heritage Green
- Greenville Holidays
- Bob Jones University
- Gravitopia Trampoline Arena
