Upstate South Carolina Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by RVLuckyorWhat

  • Plan, book, travel with confidence

  • Better together

    Save up to NZ$616 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Our guide on where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Always thinking on how I traveled half way across the world just to come and study. Sometimes I think of home and I miss it sooo much. But, this is the area I have lived for the last 3 years. This is the home far from home. I call this home, not because I have family here. It is where I have met so many wonderful people in this city. This is my #adventure from one side of the world to here!

Greenville Downtown

2 out of top 10 points of interest in this area
5/5(1 area review)

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Find hotels in Greenville Downtown

Upstate South Carolina Holiday

Our pick of the best Upstate South Carolina Hotel Deals

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
The price is NZ$469 per night from 8 Feb to 9 Feb
NZ$469
8 Feb - 9 Feb
includes taxes & fees
9.4/10 Exceptional! (442 reviews)
I would have given it five stars, but the only reason I didn’t is because breakfast they only serve bacon and pork sausage. I wish they would have had turkey sausage, vegan sausage or beef as well to choose from but the food is delicious.!!!!

Reviewed on 28 Jan 2026

Grand Bohemian Lodge Greenville, Autograph Collection
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
The price is NZ$272 per night from 22 Feb to 23 Feb
NZ$272
22 Feb - 23 Feb
includes taxes & fees
8.6/10 Excellent! (1,005 reviews)
The staff was great to us during the ice storm! Lots of places to hang out.

Reviewed on 28 Jan 2026

Hyatt Regency Greenville
Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest

2.5 out of 5
501 South Blackstock Rd Spartanburg SC
Fully refundable
The price is NZ$114 per night from 1 Mar to 2 Mar
NZ$114
1 Mar - 2 Mar
includes taxes & fees
5.8/10 (536 reviews)
Room was very spotless and clean great staff and pet friendly hotel i would recommend anyone to come here 😀 me and my girlfriend had an amazing stay

Reviewed on 28 Jan 2026

Sleep Inn Spartanburg Southwest
See all 2,938 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Upstate South Carolina

At the foot of the Cross lies my peace... A popular place for weddings in the small open-sided chapel atop the mountain at the YMCA camp. To sit in the pews and look out on the world is a great side of peace. #cross #peace #mountains #SC #relaxing #beautifulday #outdoors #traveljunkie #ktphoenixphotography

Fred W. Symmes Chapel

You can find out about the history of Cleveland with a visit to Fred W. Symmes Chapel. Wander the lakeside and forests in this relaxing area.

Fred W. Symmes Chapel
Dorm Life.

Bob Jones University

Enjoy the student vibe when you visit Bob Jones University during your travels in Greenville. Attend a sporting event or visit the shops in this family-friendly area.

Bob Jones University
Lake Jocassee, the gorgeous blue heart of the Jocassee Gorges, is actually a man-made lake. It was created when the Jocassee Dam was built in 1973. ... flooding the town. Attakulla Lodge, an old hotel, is still standing at the bottom of Lake Jocassee, under 300 feet of water. You can dive here and see a gas station and the cemetery.

Devils Fork State Park

You can take time to visit Devils Fork State Park during your travels to Salem. Wander the lakeside or discover the area's mountain views.

Devils Fork State Park

What to do in Upstate South Carolina

Greenville: Saturday Morning Breakfast Tour

Greenville: Saturday Morning Breakfast Tour

NZ$156
per adult
Greenville: Saturday Morning Breakfast Tour
Greenville Bites and Sights Lunch Tour

Greenville Bites and Sights Lunch Tour

NZ$191
per adult
Greenville Bites and Sights Lunch Tour
Delicious breakfast on a sunny Saturday morning on the terrace

Small-Group Walking Tour in Greenville with Breakfast

NZ$165
per adult
100% of travellers recommend
Small-Group Walking Tour in Greenville with Breakfast
See all activities in Upstate South Carolina

Frequently asked questions

Can I cancel my flight booking to Upstate South Carolina due to COVID-19?
Head to our Customer Service Portal for important information about changing or cancelling flights due to COVID-19. Make sure you also read through the terms and conditions of your chosen airline before booking your fare to Upstate South Carolina.
What's the best way to find cheap flights to Upstate South Carolina that have flexible change policies?
We understand that travel plans can change in the blink of an eye, so reserving a flexible ticket with Expedia is a sensible idea. Simply tick the "No change fee" box under the "Flexible change policies" filter. Your low-cost, flexible flight to Upstate South Carolina is just a few clicks away.
What are some of the general tips for travellers to Upstate South Carolina during the COVID-19 outbreak?
COVID-19 has affected how the world works in endless ways, and travel has changed with it. These tips will help you navigate these new challenges and prepare you for your trip to Upstate South Carolina:
  • Before booking anything, see if any travel bans or restrictions apply — in both your origin and destination. Get up-to-date information by reviewing government and travel websites.
  • Wear a face mask even during airport screening. A TSA employee will require you to lower your mask temporarily to verify your identity.
  • You're no longer required to hand your boarding pass (paper or electronic) directly to a TSA officer. Rather, place your pass on the scanner and then hold it up for inspection.
  • One container of liquid hand sanitizer is now allowed in your carry-on luggage. It must not be larger than 12 oz (350 ml), and you'll need to remove it from your bag for screening.
  • To reduce handling during screening, place items such as your phone and loose change into your carry-on rather than the bins.
  • Separate any food you're carrying for X-ray screening. Placing it in a clear plastic bag and into a bin reduces the need for a TSA officer to touch and inspect your belongings.

Which airlines fly to Upstate South Carolina?
Secure your ticket with American Airlines and then start piecing together your Upstate South Carolina itinerary. This leading carrier offers 19932 flights each month to Charlotte-Douglas Intl. Airport (CLT), a key gateway.
How can I find cheap tickets to Upstate South Carolina?
You'll always nab a fabulous deal with Expedia, but our "flexible dates" feature makes it that much easier. Enter your preferred flight date, then check the flexible dates box above to see a list of prices for nearby days. was the lowest price for a flight to Upstate South Carolina in the last seven days.
How much is a flight to Upstate South Carolina?
One-way trips departing from () sold for as little as in the last seven days. During this period, the price of a round-trip fare to Upstate South Carolina ranged between and . If you find a bargain ticket, book as fast as you can — these prices don't stick around.
What are the most popular airports to fly into in Upstate South Carolina?
Book your flight to Charlotte-Douglas Intl. Airport (CLT) and experience everything that Upstate South Carolina has to offer. As the region's primary entry point, about 21666 flights touch down here every month.
When is the cheapest time to fly to Upstate South Carolina?
If you'd prefer to spend your hard-earned holiday money experiencing the delights of Upstate South Carolina rather than on your trip there, leave early in the week. The most affordable day to travel is normally Tuesday, with Monday coming in second. With many people travelling over the weekend, Saturday often has the costliest fares.
How much is a plane ticket to Upstate South Carolina?
Plane fares ranged anywhere from to in the last seven days. When you're ready to book, we'll help you find a low-cost flight to Upstate South Carolina.
Which airlines with flights to Upstate South Carolina employ COVID-19 cleanliness policies?
In response to the global COVID-19 pandemic, many airlines have introduced new rules and standards to help everybody get back in the skies. These carriers include:
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.