Spa Hotels & Resorts in Seneca from NZ$121

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Seneca Spa Hotels

Tonight
1 Jan - 2 Jan
Tomorrow
2 Jan - 3 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan
No exact matches found, but these alternatives could be just right

Recommended hotels in Seneca

Aerial view
Lakeside Lodge Clemson

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1000)
"Great place to stay. "
United States
Gene
The price is NZ$235
includes taxes & fees
4 Jan - 5 Jan
Lakeside Lodge Clemson
Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (666)
"Good available parking. Room clean. Breakfast was minimal, but good. The tub was slippery and needed a mat. I almost fell a couple of times. I would stay here again."
United States
Denise
The price is NZ$155
includes taxes & fees
11 Jan - 12 Jan
Quality Inn Seneca Clemson Area US-123
Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (53)
"Excellent stay."
United States
Beonca
The price is NZ$221
includes taxes & fees
6 Jan - 7 Jan
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Lobby
Best Western Seneca-Clemson

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (643)
"The stay was amazing "
United States
Tabatha
The price is NZ$171
includes taxes & fees
8 Jan - 9 Jan
Best Western Seneca-Clemson
Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
Seneca
9.4 out of 10, Exceptional, (205)
"Nice hotel by the lake"
United States
Mike
The price is NZ$239
includes taxes & fees
6 Jan - 7 Jan
Fairfield Inn & Suites Seneca Clemson Univ Area
Lobby
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (800)
"Staff is amazing, hotel and amenities are great. "
United States
Shannon
The price is NZ$193
includes taxes & fees
11 Jan - 12 Jan
Tru by Hilton Seneca Clemson
Property grounds
Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC

Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC

Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC
Seneca
10.0 out of 10, Exceptional, (12)
"Great hidden gem in Seneca for a Clemson football weekend. Property was amazing, loved the animals…..we will be back! "
United States
Allison H.
The price is NZ$355
includes taxes & fees
4 Jan - 5 Jan
Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC
Exterior
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (669)
"Great place to stay"
United States
Jose
The price is NZ$230
includes taxes & fees
15 Jan - 16 Jan
Hampton Inn & Suites Seneca-Clemson Area
Smart TV, fireplace
Enjoy one of our RV units son less of a headache for you this vacation!

Enjoy one of our RV units son less of a headache for you this vacation!

Enjoy one of our RV units son less of a headache for you this vacation!
Seneca
8.0 out of 10, Very good, (3)
"My partner and I stayed 5 nights and we enjoyed it so much. It's such a convenient place to reside for a get away. If you're looking for that "outback" feeling but want to be cozy; look no further. Communication was always qick with responses and was more than willing to help with anything we needed! We would definitely stay again."
United States
Denise s.
The price is NZ$266
includes taxes & fees
8 Jan - 9 Jan
Enjoy one of our RV units son less of a headache for you this vacation!
Room, 1 King Bed, Non Smoking
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (722)
"Room was clean. Quiet place to rest. Lisa at the front desk was very helpful and very nice. "
United States
Teresa
The price is NZ$138
includes taxes & fees
25 Jan - 26 Jan
Days Inn by Wyndham Seneca / Clemson Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Seneca Hotel Reviews

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent
"All good"
Tonya Michelle 2-night trip
Posted 6 days ago
Hampton Inn & Suites Seneca-Clemson Area

Frequently asked questions

Looking for a spa hotel in Seneca?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Discover the lakeside setting in Seneca—worth a picture or two! Make sure you enjoy the coffee shops during your stay. Hotels with spas are the perfect way to take a break from your routine and add a layer of luxury to your weekend away.
What's there to see and do in Seneca?
Take in the sights and attractions that Seneca offers with a visit to Keowee Reservoir, Lake Keowee and Keowee Key Golf Course. If you have extra time while you're in the area, you might want to see Lake Hartwell and Oconee County Library Seneca Branch.
What is a Seneca spa hotel?
Spa hotels in Seneca provide lodging and have an on-site spa offering services such as therapies as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.

Explore a world of travel with Expedia