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Our top choices for Seneca hotels

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (689 reviews)
"Room was very clean, the grounds was in well taken care of, was safe. Overall a good place to stay."
United States
Billy
The price is NZ$160
includes taxes & fees
16 Apr - 17 Apr
Quality Inn Seneca Clemson Area US-123

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,003 reviews)
"Great place and location, great mattress, "
United States
Jeffrey
The price is NZ$236
includes taxes & fees
3 Apr - 4 Apr
Lakeside Lodge Clemson

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (214 reviews)
"Hotel and room were super clean. Hotel is fairly new and it shows. Nice view of Lake Keowee. Breakfast was quite good & excellent coffee. Would definitely stay there again. "
United States
Matthew
The price is NZ$230
includes taxes & fees
12 Apr - 13 Apr
Fairfield Inn & Suites Seneca Clemson Univ Area

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (689 reviews)
"Everything was great. "
United States
Wendy
The price is NZ$254
includes taxes & fees
26 Apr - 27 Apr
Hampton Inn & Suites Seneca-Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (735 reviews)
"Our stay was ok..the bathroom was in need of renovation "
United States
clyde
The price is NZ$133
includes taxes & fees
12 Apr - 13 Apr
Days Inn by Wyndham Seneca / Clemson Area

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (653 reviews)
"Room was clean and staff was very efficient. "
United States
Judith
The price is NZ$187
includes taxes & fees
14 Apr - 15 Apr
Best Western Seneca-Clemson

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (66 reviews)
"Excellent stay."
United States
Beonca
The price is NZ$266
includes taxes & fees
7 Apr - 8 Apr
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (820 reviews)
"Nice clean hotel with several food options available nearby."
United States
kelsey
The price is NZ$217
includes taxes & fees
13 Apr - 14 Apr
Tru by Hilton Seneca Clemson

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (797 reviews)
"Fantastic place and staff most accommodating "
United States
Walter
The price is NZ$122
includes taxes & fees
5 Apr - 6 Apr
Baymont by Wyndham Easley/Greenville

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very good, (1,001 reviews)
"Good stay and breakfast"
United States
Jeff
The price is NZ$195
includes taxes & fees
15 Apr - 16 Apr
Best Western Plus Clemson Hotel & Conference Center

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
Anderson
8.0 out of 10, Very good, (1,010 reviews)
"Awesome place "
United States
Tramaness
The price is NZ$113
includes taxes & fees
12 Apr - 13 Apr
Days Inn by Wyndham Anderson

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
Anderson
9.0 out of 10, Wonderful, (607 reviews)
"Clean rooms, friendly staff, great breakfast options!"
United States
Lauren
The price is NZ$199
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Anderson/ Alliance Business Park
2.5 star property
Anderson
9.2 out of 10, Wonderful, (832 reviews)
"Staff were so helpful , place was clean and food spots near by"
United States
osiry
The price is NZ$219
includes taxes & fees
12 Apr - 13 Apr
Hampton Inn Anderson/ Alliance Business Park

Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.2 out of 10, Very good, (1,003 reviews)
"All of the staff we encountered were extremely nice and helpful. The beds were very comfortable thoroughly enjoyed our stay."
United States
Tina
The price is NZ$158
includes taxes & fees
2 Apr - 3 Apr
Inn @ Clemson

Hampton Inn Hartwell

Hampton Inn Hartwell
2.5 star property
Hartwell
9.0 out of 10, Wonderful, (365 reviews)
"Great stay"
United States
Annmargaret
The price is NZ$265
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn Hartwell

Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville
2.5 star property
Easley
7.0 out of 10, Good, (419 reviews)
"Clean room Friendly Staff"
United States
Andrina
The price is NZ$108
includes taxes & fees
8 Apr - 9 Apr
Quality Inn & Suites Easley - Greenville

Home2 Suites by Hilton Anderson Downtown

Home2 Suites by Hilton Anderson Downtown
3.0 star property
Anderson
9.4 out of 10, Exceptional, (233 reviews)
"Room was great and the staff polite and helpful "
United States
Sheila D
The price is NZ$276
includes taxes & fees
12 Apr - 13 Apr
Home2 Suites by Hilton Anderson Downtown

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (907 reviews)
"Staff was great and our beds were very comfortable!"
United States
Laurie
The price is NZ$101
includes taxes & fees
12 Apr - 13 Apr
Quality Inn Clemson near University

Holiday Inn Anderson by IHG

Holiday Inn Anderson by IHG
3.0 star property
Anderson
8.8 out of 10, Excellent, (714 reviews)
"Great hotel in all regards"
Canada
Dan
The price is NZ$213
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Anderson by IHG

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
Anderson
9.0 out of 10, Wonderful, (710 reviews)
"Great stay. Clean room, quiet stay, convenient location."
United States
Scott
The price is NZ$192
includes taxes & fees
12 Apr - 13 Apr
Hilton Garden Inn Anderson
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Our guide on where to stay in Seneca

Find the best Seneca areas for the activities you enjoy most. Learn more about Seneca
Learn more about Seneca

Downtown

City centre Seneca captures the essence of small-town Southern charm with its well-preserved railway heritage and historic brick buildings. Tree-lined streets lead to charming shops and local eateries housed in structures dating back to the 1800s. Ram Cat Alley's colourful murals tell stories of local history while the old courthouse square hosts community gatherings. This walkable district offers a peaceful retreat from big city life. Visitors can browse antique stores for railway memorabilia, sample authentic Southern comfort food, or explore the cultural exhibits at the Bertha Lee Strickland Museum. The nearby Lake Keowee provides outdoor recreation just minutes away.

Serenity Bay

Serenity Bay offers a peaceful retreat within Saxony Forest's coastal embrace. The quiet residential streets wind through mature trees, creating a tranquil atmosphere away from tourist crowds. Nature lovers can explore nearby Lake Keowee or enjoy the neighborhood's forest trails. The area perfectly balances woodland serenity with beach proximity. Visitors should plan for self-contained holiday rentals rather than hotels. While dining options are limited within the area, the natural surroundings provide ideal conditions for relaxation and outdoor recreation.

Pine Ridge Point

Lake Keowee's serene waters lap against the shores of Pine Ridge Point, a tranquil residential haven in Seneca. Private docks stretch into crystal-clear waters where boats gently bob. Towering pines create natural privacy between lakefront homes. Visitors enjoy peaceful mornings watching mist rise over the water. This area offers an authentic lakeside living experience without tourist crowds. Holiday rentals range from cosy cabins to luxury estates with private boat slips. Days revolve around swimming, fishing, and water sports on Lake Keowee. Nature trails wind through mature forests for hiking and birdwatching.

Indian Oaks

Indian Oaks offers a tranquil retreat in suburban Seneca where mature oak trees create natural canopies over peaceful residential streets. This family-oriented community provides an authentic glimpse into American suburban living without tourist crowds. Landscaped yards and community green spaces showcase South Carolina's native beauty. Visitors can enjoy quiet morning walks on spacious pavements while listening to birdsong. Lake Keowee lies just beyond the area boundaries for those seeking water activities. With minimal commercial presence, Indian Oaks delivers a genuinely restful experience away from urban bustle.

Stay near popular Seneca attractions

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Lake Keowee South Carolina

Top Seneca Hotel Reviews

More cheap accommodation in Seneca

Frequently asked questions

Where is the best place for a stay in Seneca?
Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel is a short 15-minute walk from Clemson University, and it offers free breakfast and free parking. Traveller reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.
What are some of the best holiday rentals that Seneca has to offer?
4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!: This highly rated holiday home rental in Seneca is located on a lake, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 5 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and an arcade/games room. Some other homes for rent in Seneca include Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock and Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson.. See all vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
What's the best family accommodation in Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Also, attractions in the area such as Ultimate Action Sports are fun for the whole family. Find more child-friendly accommodations in Seneca.
What is the top LGBTQ-friendly accommodation in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Tru by Hilton Seneca Clemson is another good choice for your trip. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best dog-friendly hotel in Seneca?
Lakeside Lodge Clemson is a top hotel for people travelling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices for you and your pet's trip include Quality Inn Seneca Clemson Area US-123 and Tru by Hilton Seneca Clemson. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Lakeside Lodge Clemson: Hotel located near Clemson University. Offers free self parking, a seasonal outdoor pool and complimentary wireless Internet access. Hampton Inn & Suites Seneca-Clemson Area and Quality Inn Seneca Clemson Area US-123 are two additional hotels that feature an on-site pool. View all hotels with pools in Seneca.
What is staying in Seneca like?
Visitors to Seneca will definitely enjoy the sporting events, lakeside setting and university setting. Welcoming and scenic, this city also attracts tourists with its cafes. In Seneca, there are 302 hotels and other accommodation options to choose from. Find out more about Seneca.
What should I see while I'm in Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Take a look at what more there is to see and do in Expedia's Seneca guide.
What's the seasonal weather in Seneca?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Seneca is 1565 mm.

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