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Our top choices for Seneca hotels

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (73 reviews)
"Awesome place "
United States
Jason
The price is NZ$251
includes taxes & fees
16 June - 17 June
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (702 reviews)
"Clean room comfortable beds"
United States
Cheryl
The price is NZ$166
includes taxes & fees
14 June - 15 June
Quality Inn Seneca Clemson Area US-123

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,005 reviews)
"This place is tops! The area is great, rooms were wonderful, and amenities were amazing. Definitely plan on staying again asap!"
United States
Valarie Tina
The price is NZ$232
includes taxes & fees
18 May - 19 May
Lakeside Lodge Clemson

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (230 reviews)
"Excellent in every way … staff, room, amenities and very comfortable bed!"
United States
Sarah
The price is NZ$244
includes taxes & fees
24 May - 25 May
Fairfield Inn & Suites Seneca Clemson Univ Area

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (659 reviews)
"Room was clean and staff was very efficient. "
United States
Judith
The price is NZ$184
includes taxes & fees
19 May - 20 May
Best Western Seneca-Clemson

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (840 reviews)
"The staff was super friendly. The room was great and so was the breakfast. "
United States
Sydney
The price is NZ$215
includes taxes & fees
25 May - 26 May
Tru by Hilton Seneca Clemson

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (710 reviews)
"Nice stay"
United States
Stephanie
The price is NZ$229
includes taxes & fees
7 June - 8 June
Hampton Inn & Suites Seneca-Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (749 reviews)
"Strong disinfectant smell in room. Beds and linens were very comfortable."
United States
Mary Jane
The price is NZ$136
includes taxes & fees
7 June - 8 June
Days Inn by Wyndham Seneca / Clemson Area

Carolina Inn Anderson Clemson Area

Carolina Inn Anderson Clemson Area
2.5 star property
Anderson
10.0 out of 10, Exceptional, (1 review)
"The staff is great "
United States
Luis Fernando
The price is NZ$105
includes taxes & fees
18 May - 19 May
Carolina Inn Anderson Clemson Area

Hampton Inn Hartwell

Hampton Inn Hartwell
2.5 star property
Hartwell
9.0 out of 10, Wonderful, (370 reviews)
"Nice hotel for the area. "
United States
Judith
The price is NZ$219
includes taxes & fees
24 May - 25 May
Hampton Inn Hartwell

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
Anderson
9.2 out of 10, Wonderful, (615 reviews)
"Clean rooms, friendly staff, great breakfast options!"
United States
Lauren
The price is NZ$209
includes taxes & fees
24 May - 25 May
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
Pickens
10.0 out of 10, Exceptional, (3 reviews)
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
United States
Katlynn
The price is NZ$445
includes taxes & fees
20 May - 21 May
Carolina Camp Cedar

Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
Clemson
9.6 out of 10, Exceptional, (10 reviews)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
The price is NZ$407
includes taxes & fees
18 May - 19 May
Clemson Memorabilia House

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (823 reviews)
"Excellent stay... quiet, clean and very safe! Manager was amazing and took great care of us on arrival even though we were a bit early! 10/10...would recommend!!"
United States
Scott
The price is NZ$148
includes taxes & fees
25 May - 26 May
Baymont by Wyndham Easley/Greenville

Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville
2.5 star property
Easley
7.0 out of 10, Good, (441 reviews)
"The manager was great. Room quality for value was also great."
United States
Jennifer
The price is NZ$121
includes taxes & fees
20 May - 21 May
Quality Inn & Suites Easley - Greenville

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (922 reviews)
"Super wonderful staff, easy check in, good pick up spot for the concert, good location, fantastic head cleaning/room service lady. Didn't have breakfast there, but had a good set up for that. "
United States
Courtney
The price is NZ$108
includes taxes & fees
7 June - 8 June
Quality Inn Clemson near University

Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Anderson/ Alliance Business Park
2.5 star property
Anderson
9.2 out of 10, Wonderful, (839 reviews)
"Staff were so helpful , place was clean and food spots near by"
United States
osiry
The price is NZ$216
includes taxes & fees
25 May - 26 May
Hampton Inn Anderson/ Alliance Business Park

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
Anderson
8.0 out of 10, Very good, (1,004 reviews)
"Lovely stay, clean room, quiet property, wonderful pleasant staff and top notch location! "
United States
N
The price is NZ$111
includes taxes & fees
11 June - 12 June
Days Inn by Wyndham Anderson

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
Anderson
9.0 out of 10, Wonderful, (725 reviews)
"Great place to stay"
United States
Maureen
The price is NZ$189
includes taxes & fees
25 May - 26 May
Hilton Garden Inn Anderson

Home2 Suites by Hilton Anderson Downtown

Home2 Suites by Hilton Anderson Downtown
3.0 star property
Anderson
9.4 out of 10, Exceptional, (241 reviews)
"Great room and staff and breakfast was great "
United States
reginald
The price is NZ$266
includes taxes & fees
31 May - 1 June
Home2 Suites by Hilton Anderson Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Seneca

Find the best Seneca areas for the activities you enjoy most. Learn more about Seneca
Learn more about Seneca

Downtown

City centre Seneca captures the essence of small-town Southern charm with its well-preserved railway heritage and historic brick buildings. Tree-lined streets lead to charming shops and local eateries housed in structures dating back to the 1800s. Ram Cat Alley's colourful murals tell stories of local history while the old courthouse square hosts community gatherings. This walkable district offers a peaceful retreat from big city life. Visitors can browse antique stores for railway memorabilia, sample authentic Southern comfort food, or explore the cultural exhibits at the Bertha Lee Strickland Museum. The nearby Lake Keowee provides outdoor recreation just minutes away.

Serenity Bay

Serenity Bay offers a peaceful retreat within Saxony Forest's coastal embrace. The quiet residential streets wind through mature trees, creating a tranquil atmosphere away from tourist crowds. Nature lovers can explore nearby Lake Keowee or enjoy the neighborhood's forest trails. The area perfectly balances woodland serenity with beach proximity. Visitors should plan for self-contained holiday rentals rather than hotels. While dining options are limited within the area, the natural surroundings provide ideal conditions for relaxation and outdoor recreation.

Pine Ridge Point

Lake Keowee's serene waters lap against the shores of Pine Ridge Point, a tranquil residential haven in Seneca. Private docks stretch into crystal-clear waters where boats gently bob. Towering pines create natural privacy between lakefront homes. Visitors enjoy peaceful mornings watching mist rise over the water. This area offers an authentic lakeside living experience without tourist crowds. Holiday rentals range from cosy cabins to luxury estates with private boat slips. Days revolve around swimming, fishing, and water sports on Lake Keowee. Nature trails wind through mature forests for hiking and birdwatching.

Indian Oaks

Indian Oaks offers a tranquil retreat in suburban Seneca where mature oak trees create natural canopies over peaceful residential streets. This family-oriented community provides an authentic glimpse into American suburban living without tourist crowds. Landscaped yards and community green spaces showcase South Carolina's native beauty. Visitors can enjoy quiet morning walks on spacious pavements while listening to birdsong. Lake Keowee lies just beyond the area boundaries for those seeking water activities. With minimal commercial presence, Indian Oaks delivers a genuinely restful experience away from urban bustle.

Stay near popular Seneca attractions

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Lake Keowee South Carolina

Top Seneca Hotel Reviews

More cheap accommodation in Seneca

Frequently asked questions

Where is the best place for a stay in Seneca?
Lakeside Lodge Clemson is one of the top choices for your stay based on our traveller data. This hotel offers a restaurant and free parking. Other good options for your visit include Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy and Quality Inn Seneca Clemson Area US-123. See all available top hotels, or vacation rentals in Seneca.
What are some of the best holiday rentals that Seneca has to offer?
4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!: This highly rated holiday home rental in Seneca is located on a lake, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 5 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and an arcade/games room. Some other homes for rent in Seneca include Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub and Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock. See all vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
What's the best family accommodation in Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Also, attractions in the area such as Ultimate Action Sports are fun for the whole family. Find more child-friendly accommodations in Seneca.
What is the top LGBTQ-friendly accommodation in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Tru by Hilton Seneca Clemson is another good choice for your trip. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best dog-friendly hotel in Seneca?
Lakeside Lodge Clemson is a top hotel for people travelling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices for you and your pet's trip include Quality Inn Seneca Clemson Area US-123 and Tru by Hilton Seneca Clemson. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Lakeside Lodge Clemson: Hotel located near Clemson University. Features free self parking, a seasonal outdoor pool and complimentary wireless Internet access. Quality Inn Seneca Clemson Area US-123 and Fairfield Inn & Suites Seneca Clemson Univ Area are two additional hotels that feature an on-site pool. View all hotels with pools in Seneca.
What is staying in Seneca like?
Visitors to Seneca will definitely enjoy the sporting events, lakeside setting and university setting. Welcoming and scenic, this city also attracts tourists with its cafes. In Seneca, there are 308 hotels and other accommodation options to choose from. Find out more about Seneca.
What should I see while I'm in Seneca?
Cultural venues include Oconee Community Theatre and The Gauntlet. Natural beauty is on display at Lake Keowee, Lake Hartwell and Keowee Reservoir. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Take a look at what more there is to see and do in Expedia's Seneca guide.
What's the seasonal weather in Seneca?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Seneca is 1565 mm.

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