
Seneca Holidays
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Our guide on where to stay in Seneca
Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca

Downtown
2 out of top 10 points of interest in this area
If you're spending some time in Downtown, Seneca Historic District and Oconee County Library Seneca Branch are top sights worth seeing.
Seneca Holiday
Our pick of the best Seneca Hotel Deals

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is NZ$159 per night from 5 Oct to 6 Oct
NZ$159
5 Oct - 6 Oct
includes taxes & fees
7.8/10 Good! (643 reviews)
"Staff was friendly very clean"
Reviewed on 22 Sept 2025

Lakeside Lodge Clemson
13500 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is NZ$231 per night from 25 Sept to 26 Sept
NZ$231
25 Sept - 26 Sept
includes taxes & fees
8.8/10 Excellent! (1,006 reviews)
"Large living area much better than a standard hotel. Very close to shopping and restaurants."
Reviewed on 17 Sept 2025

Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is NZ$228 per night from 28 Sept to 29 Sept
NZ$228
28 Sept - 29 Sept
includes taxes & fees
9.2/10 Wonderful! (635 reviews)
"Everything was good"
Reviewed on 29 Aug 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More holiday ideas
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.