A calm lake with mountains in the background.

Seneca Holiday Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Seneca holiday rentals

1. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (120 reviews)
"Perfect location for getting away in a quiet cabin!"
United States
Lori
The price is NZ$246
includes taxes & fees
9 Dec - 10 Dec
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2. Enjoyable 1-bedroom hotel suites with AC in Seneca

Enjoyable 1-bedroom hotel suites with AC in Seneca
Downtown
The price is NZ$372
includes taxes & fees
12 Nov - 13 Nov
Enjoyable 1-bedroom hotel suites with AC in Seneca

3. Cozy Clemson TIny House Cabin

Cozy Clemson TIny House Cabin
Seneca
10.0 out of 10, Exceptional, (4 reviews)
"Extremely clean and well maintained, suited our needs for a long weekend just fine. We even cooked a couple of meals. We enjoyed using the fire pit for the first campfire of the season."
United States
Rebecca J.
The price is NZ$365
includes taxes & fees
11 Nov - 12 Nov
Cozy Clemson TIny House Cabin

4. Peaceful 3-bedroom home 4 miles from Clemson.

Peaceful 3-bedroom home 4 miles from Clemson.
Seneca
10.0 out of 10, Exceptional, (1 review)
"We were very comfortable for our stay and the property was everything we expected and more."
United States
Justin K.
The price is NZ$498
includes taxes & fees
11 Nov - 12 Nov
Peaceful 3-bedroom home 4 miles from Clemson.

5. Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms
Seneca
10.0 out of 10, Exceptional, (33 reviews)
"Great place to stay. The rooms were clean and we had plenty of space. Definitely would come back!"
United States
Brandon P.
The price is NZ$653
includes taxes & fees
1 Dec - 2 Dec
Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

6. Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Seneca
10.0 out of 10, Exceptional, (17 reviews)
"Perfect pet friendly spot to enjoy a weekend getaway! Quiet campground, homey vibe, and awesome location!"
United States
Josie G.
The price is NZ$336
includes taxes & fees
11 Nov - 12 Nov
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

7. Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Downtown
10.0 out of 10, Exceptional, (23 reviews)
"This home was cozy and convenient. Communication was great; they are kind folks that enjoy what they do! We are grateful we could stay there!"
United States
Krystine F.
The price is NZ$632
includes taxes & fees
11 Nov - 12 Nov
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

8. Camping on Fancy-Perfect for small family getaway or couples retreat!

Camping on Fancy-Perfect for small family getaway or couples retreat!
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Perfect space for me and my husband to stay for family weekend at Clemson. Perfectly located, comfortable, and the hostess was incredibly kind and thoughtful.We will definitely be staying here again."
United States
Regina J.
The price is NZ$472
includes taxes & fees
22 Nov - 23 Nov
Camping on Fancy-Perfect for small family getaway or couples retreat!

9. 8 Mi to Clemson: Peaceful Family Home w/ Yard

8 Mi to Clemson: Peaceful Family Home w/ Yard
3.0 star property
Seneca
10.0 out of 10, Exceptional, (1 review)
"The place was all out perfect the owner was polite and perfect. It was a very peaceful place to stay thank you so much."
United States
Jason
The price is NZ$897
includes taxes & fees
27 Nov - 28 Nov
8 Mi to Clemson: Peaceful Family Home w/ Yard

10. Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
Seneca
6.0 out of 10, (2 reviews)
"The house was immaculate and welcoming. It was well stocked with everything you could possibly need. We would definitely stay again."
United States
Stacey W.
The price is NZ$765
includes taxes & fees
11 Nov - 12 Nov
Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

11. Renovated 3BR near Lake Keowee & Clemson

Renovated 3BR near Lake Keowee & Clemson
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Fantastic location and really nicely done home. It was a perfect touch having a desk in one of the rooms to be able to get work done."
United States
Brenda B.
The price is NZ$645
includes taxes & fees
9 Dec - 10 Dec
Renovated 3BR near Lake Keowee & Clemson

12. 3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Seneca
9.8 out of 10, Exceptional, (13 reviews)
"Easy check in, pet-friendly, great location!!"
United States
Jason M.
The price is NZ$631
includes taxes & fees
11 Nov - 12 Nov
3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

13. Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
Seneca
8.4 out of 10, Very good, (8 reviews)
"Adorable and clean house! The yard is beautiful "
United States
Diana H.
The price is NZ$503
includes taxes & fees
29 Nov - 30 Nov
Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

14. Lakefront Retreat l Near Clemson, Hot Tub, Game Room, Kayaks, Private Dock

Lakefront Retreat l Near Clemson, Hot Tub, Game Room, Kayaks, Private Dock
Seneca
9.6 out of 10, Exceptional, (13 reviews)
"We had a great time at Seneca Lake House. We would definitely stay here again. "
United States
Scott M.
The price is NZ$1,443
includes taxes & fees
17 Nov - 18 Nov
Lakefront Retreat l Near Clemson, Hot Tub, Game Room, Kayaks, Private Dock

15. The Big Golf House- 10 miles to Clemson

The Big Golf House- 10 miles to Clemson
Seneca
10.0 out of 10, Exceptional, (4 reviews)
"Great house and host!"
United States
David E.
The price is NZ$1,038
includes taxes & fees
11 Nov - 12 Nov
The Big Golf House- 10 miles to Clemson

16. Waterfront 3br home on Lake Hartwell near Clemson

Waterfront 3br home on Lake Hartwell near Clemson
Seneca
9.8 out of 10, Exceptional, (19 reviews)
"We enjoyed our stay. Had everything we needed. "
United States
Diane S.
The price is NZ$908
includes taxes & fees
20 Nov - 21 Nov
Waterfront 3br home on Lake Hartwell near Clemson

17. Earth Dome @ Seneca Treehouse Project

Earth Dome @ Seneca Treehouse Project
Seneca
The price is NZ$493
includes taxes & fees
8 Dec - 9 Dec
Earth Dome @ Seneca Treehouse Project

18. Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
Seneca
9.6 out of 10, Exceptional, (15 reviews)
"Everything was lovely."
United States
Allison C.
The price is NZ$1,136
includes taxes & fees
11 Nov - 12 Nov
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

19. Perfect 1-bedroom hotel suites with AC in fabulous Seneca- ROOM 2

Perfect 1-bedroom hotel suites with AC in fabulous Seneca- ROOM 2
Downtown
The price is NZ$387
includes taxes & fees
11 Dec - 12 Dec
Perfect 1-bedroom hotel suites with AC in fabulous Seneca- ROOM 2

20. Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
Clemson
9.6 out of 10, Exceptional, (10 reviews)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
The price is NZ$422
includes taxes & fees
1 Dec - 2 Dec
Clemson Memorabilia House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Seneca Hotel Reviews

Find out more about Seneca

You always said you would go on a dream holiday someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannonball into the deep end. Go ahead, unplug and unwind in style. When you book one of our Seneca holiday rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your holiday just got upgraded.

As much as you love your vacation rental, it’s always good to get out and explore to soak up Seneca. Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in Seneca. Seeing all the best attractions is bound to make you fall in love with Seneca. Who knows, you may even be tempted to extend your stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. 

It’s your escape so why share it? You deserve your own slice of paradise. Booking your holiday rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in Seneca short-term rentals, that won’t be hard to do.

Explore a world of travel with Expedia

Frequently asked questions

Are there holiday rentals in Seneca?

Yes, there are holiday rentals in Seneca close to Blue Ridge Arts Center, or you can select a more secluded option if you're looking for a relaxing stay. Discover why Seneca is known for its marina and lakeside. While you're here, grab a bite or have a drink at the coffee shops.

What are some of the best holiday rentals that Seneca has to offer?

Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water: This highly rated holiday home rental in Seneca is located on a lake, and has a fireplace, a patio and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. You can relax into your holiday with a garden and a selection of games. Some other homes for rent in Seneca include Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub and New to VRBO! Big water views, private dock, pool table, 15 min Clemson!.

How many holiday rentals are there in Seneca?

Choose from 217 Expedia holiday rentals in Seneca for a memorable holiday.

What’s there to see and do in Seneca?

Cultural attractions include The Gauntlet and Oconee Community Theatre, whereas Lake Keowee and Lake Hartwell are a couple of picturesque spots to enjoy the outdoors. While here, Keowee Key Golf Course and Oconee County Library Seneca Branch are other places worth a visit.

What’s a holiday rental in Seneca like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Seneca. Holiday rentals offer extras such as WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about a sanitised environment, a holiday rental can offer a sense of seclusion away from public hotel lifts and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also get more space in a holiday rental than in a traditional hotel, which is another reason why a holiday rental is an attractive choice for family trips.