Spa Hotels & Resorts in San Francisco

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on San Francisco Spa Hotels

Tonight
23 Nov - 24 Nov
Tomorrow
24 Nov - 25 Nov
Next weekend
28 Nov - 30 Nov
In two weeks
5 Dec - 7 Dec

Best San Francisco Spa Hotels

Treatment room
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1018)
"Wonderful stay!"
United States
Martha
The price is NZ$258
includes taxes & fees
29 Nov - 30 Nov
Las Americas Golden Tower Panama
Couples treatment room(s), sauna, hot tub, steam room
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 star property
San Francisco
8.4 out of 10, Very good, (1219)
"Great stay "
United States
Mark
Megapolis Hotel Panamá
Couples treatment room(s), sauna, hot tub, steam room
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4.0 star property
San Francisco
8.6 out of 10, Excellent, (1401)
"Good place for a short stay"
United States
carlos
Decapolis Hotel Panama City
Executive Suite, 1 King Bed, Partial Ocean View | Bathroom
JW Marriott Panama

JW Marriott Panama

5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1009)
"Spotless, friendly and great food. Great pools a restaurants. "
Canada
David
The price is NZ$468
includes taxes & fees
10 Dec - 11 Dec
JW Marriott Panama
View from property
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2143)
"Very nice hotel, all amenities met our needs. "
Canada
gordon
The price is NZ$244
includes taxes & fees
24 Nov - 25 Nov
Plaza Paitilla Inn Hotel
Couples treatment room(s), sauna, hot tub, Turkish bath/hammam
Sheraton Grand Panama

Sheraton Grand Panama

4.0 star property
San Francisco
8.6 out of 10, Excellent, (979)
"Centrally located and friendly staff "
United States
Julio
The price is NZ$265
includes taxes & fees
29 Nov - 30 Nov
Sheraton Grand Panama
Outdoor pool
Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments

4.0 star property
San Francisco
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
United States
GISY ITZEL
The price is NZ$495
includes taxes & fees
30 Nov - 1 Dec
Wanders Panama by Boutique Apartments
Couples treatment room(s), sauna, steam room, body treatments
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5.0 star property
Veracruz
8.0 out of 10, Very good, (1004)
"Staff very friendly, clean room, amazing food&drinks"
United States
Ashley Ethel
The price is NZ$326
includes taxes & fees
14 Dec - 15 Dec
The Westin Playa Bonita Panama
Lobby
Hyatt Regency Panama City

Hyatt Regency Panama City

4.5 star property
Bella Vista
10.0 out of 10, Exceptional, (112)
"Great stay for a birthday celebration "
United States
Carmenzina
The price is NZ$293
includes taxes & fees
28 Nov - 29 Nov
Hyatt Regency Panama City
Meeting facility
W Panama

W Panama

5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1002)
"Clean room, great views, great staff!"
United States
Ashley
The price is NZ$359
includes taxes & fees
5 Dec - 6 Dec
W Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top San Francisco Hotel Reviews

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

10/10 Excellent
"I had a great stay at the Ramada Plaza by Wyndham Panama Punta Pacifica. The room was clean, comfortable, and well-maintained, and the staff were consistently friendly and helpful. The location is convenient, with easy access to shops, restaurants, and nearby attractions. Amenities like the pool, breakfast, and overall atmosphere made the experience even better. I’d definitely stay here again and recommend it to anyone visiting Panama City."
Reginald 4-night trip
Posted 3 days ago
Ramada Plaza by Wyndham Panama Punta Pacifica

Explore a world of travel with Expedia

Frequently asked questions

Looking for a spa hotel in San Francisco?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Make sure you enjoy the many popular restaurants during your stay. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in San Francisco?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping centre and a rooftop terrace. Enjoy a facial, body scrub or detox wrap at the on-site spa. Other popular spa hotels in San Francisco include Las Americas Golden Tower Panama and Sheraton Grand Panama.
How many spa hotels will I find in San Francisco?
Among Expedia's 215 accommodation options in San Francisco, there are 5 spa hotels.
What's there to see and do in San Francisco?
Enjoy San Francisco and visit Multiplaza Pacific Mall, Calle 50 and Avenida Balboa. If you have spare time during your trip, you might want to make a stop at Multicentro Panama and Panama Canal Murals.
What is a San Francisco spa hotel?
Spa hotels in San Francisco provide lodging and have an on-site spa which offers services such as couples massages and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.