A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City Holiday Rentals

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Check prices for these dates

In two weeks
16 Oct - 18 Oct
In two months
27 Nov - 29 Nov
In three months
25 Dec - 27 Dec
In four months
22 Jan - 24 Jan

Our top choices for Panama City holiday rentals

A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

1. La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (212 reviews)
"Location in old town, across from Plaza Simon Bolivar, is the perfect place to venture around old town and the new city. Great restaurants and shops within easy walking distance. I relied on recommendations from the staff for a couple of things and their selections exceeded my expectations. Highly recommend staying if visiting Panama City."
United States
David
The price is NZ$284
includes taxes & fees
5 Oct - 6 Oct
La Isabela Suites
A modern hotel entrance with a well-lit facade, a prominent sign, and a landscaped garden area.

2. Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.2 out of 10, Very good, (136 reviews)
"Great location and very nice hotel. Great pool and restaurants."
Canada
Howard
The price is NZ$348
includes taxes & fees
6 Oct - 7 Oct
Yoo Panamá by Boutique Apartments
A rooftop pool with a city view, lounge chairs, and a clear sky.

3. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este
9.2 out of 10, Wonderful, (385 reviews)
"Nice place good location"
United States
Rame
The price is NZ$295
includes taxes & fees
3 Oct - 4 Oct
Corporate Stays Arcadia | Executive Furnished Apartments
A modern hotel lobby with a marble staircase, seating areas, and a large mirror reflecting the space.

4. Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (584 reviews)
"Restaurants nearby are nice. Room was quiet which is an accomplishment for Panama City."
United States
Robert
The price is NZ$180
includes taxes & fees
1 Oct - 2 Oct
Torres de Alba Hotel & Suites
A multi-story building with balconies, large windows, and a clear blue sky.

5. Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (203 reviews)
"Great food and location"
United States
James
The price is NZ$298
includes taxes & fees
31 Oct - 1 Nov
Las Clementinas
A rooftop pool area with lounge chairs and a table, overlooking a cityscape with tall buildings.

6. Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
8.0 out of 10, Very good, (376 reviews)
"Great stay!!!!"
United States
fitz
The price is NZ$287
includes taxes & fees
6 Oct - 7 Oct
Boutique Apartments Panama
A modern living room with a sofa, armchair, dining table, and kitchen area with a TV and appliances.

7. Modern Apartments at The Gray Prime Location

Modern Apartments at The Gray Prime Location
4.0 star property
Bella Vista
8.4 out of 10, Very good, (17 reviews)
"I love the place and it was in walking distance to many places if you want a uber"
United States
Denise
The price is NZ$147
includes taxes & fees
8 Oct - 9 Oct
Modern Apartments at The Gray Prime Location
A rooftop pool with lounge chairs and a cityscape view.

8. Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (768 reviews)
"Front desk staff were very friendly and accommodating. Clear communication throughout my stay. Breakfast varied day to day which was nice. Enjoyed the omelette bar. Overall great location and clean spacious rooms."
United States
Markeisha
The price is NZ$208
includes taxes & fees
1 Oct - 2 Oct
Marriott Executive Apartments Panama City, Finisterre
A modern living room with a sofa, a TV, a small table, and a balcony with a view of the city.

9. Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
9.0 out of 10, Wonderful, (2 reviews)
"Perfect"
United States
Lorenz
The price is NZ$397
includes taxes & fees
15 Oct - 16 Oct
Living 73 Panamá by Boutique Apartments
An outdoor seating area with tables and chairs, a tree with pink blossoms, and a cityscape view.

10. Modern Design Apartments near Sortis

Modern Design Apartments near Sortis
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (11 reviews)
"This property was much more than I expected, room and property was clean, lots of restaurants around the area, easy to get around, will certainly be back at this property"
United States
Kareem
The price is NZ$122
includes taxes & fees
6 Oct - 7 Oct
Modern Design Apartments near Sortis
A rooftop pool with lounge chairs and a bar, overlooking a city skyline at dusk.

11. Yoo Panama Luxury Ocean View Apartment

Yoo Panama Luxury Ocean View Apartment
3.5 star property
Bella Vista
8.4 out of 10, Very good, (6 reviews)
"Good price for the location."
United States
Mark
The price is NZ$241
includes taxes & fees
15 Oct - 16 Oct
Yoo Panama Luxury Ocean View Apartment
A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

12. Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.8 out of 10, Good, (234 reviews)
"very nice place to stay"
United States
purabi
The price is NZ$340
includes taxes & fees
1 Oct - 2 Oct
Boutique Apartments Panamá Coco del Mar
A modern building with a sign reading "LA RESIDENCE" and a car parked in front.

13. La Résidence Panamá

La Résidence Panamá
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (21 reviews)
"Excellent rooms and fantastic staff!"
United States
Mohamad
The price is NZ$256
includes taxes & fees
4 Oct - 5 Oct
La Résidence Panamá
A modern outdoor swimming pool with a clear view of a tall building in the background.

14. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.6 out of 10, Excellent, (35 reviews)
"Modern and clean, including a pool and gym with stunning view. Staff were wonderful. Basic but good breakfast included. Better than a hotel."
United States
David
The price is NZ$265
includes taxes & fees
9 Oct - 10 Oct
Dovle Residences by HMS-Preferred Member
A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

15. Casco View Life Residences

Casco View Life Residences
4.0 star property
Santa Ana
9.0 out of 10, Wonderful, (106 reviews)
"Amazing location and comfort"
United States
Ruben
The price is NZ$205
includes taxes & fees
8 Oct - 9 Oct
Casco View Life Residences
A modern living room with a sofa, a coffee table, a TV, and a dining area with chairs and a table.

16. La Moderna Downtown Nights by Wynwood

La Moderna Downtown Nights by Wynwood
3.0 star property
Casco Viejo
7.2 out of 10, Good, (51 reviews)
"Great place"
United States
Ross
The price is NZ$174
includes taxes & fees
1 Oct - 2 Oct
La Moderna Downtown Nights by Wynwood
A tall, modern skyscraper with a grid-like facade and numerous windows.

17. Luxury City View Apartments at Worldwide

Luxury City View Apartments at Worldwide
3.0 star property
Bella Vista
10.0 out of 10, Exceptional, (2 reviews)
"I had a wonderful stay at this property The property was exceptionally clean, and the staff went above and beyond to make sure I felt welcome. Early check in. Highly recommended."
United States
Andre
The price is NZ$143
includes taxes & fees
11 Oct - 12 Oct
Luxury City View Apartments at Worldwide
A bedroom with a wooden ceiling, a bed with a headboard, bedside lamps, and an air conditioning unit.

18. Modern apartment in the city center

Modern apartment in the city center
2.0 star property
Bella Vista
The price is NZ$160
includes taxes & fees
1 Oct - 2 Oct
Modern apartment in the city center
A modern hotel pool area with a circular hot tub, lounge chairs, and a view of the city skyline.

19. Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (4 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is NZ$398
includes taxes & fees
1 Oct - 2 Oct
Wanders Panama by Boutique Apartments
A modern living room with a flat-screen TV, a blue cabinet, a round coffee table, and a kitchen area with bar stools.

20. The Hub Modern Apartments by Wynwood

The Hub Modern Apartments by Wynwood
3.0 star property
San Francisco
The Hub Modern Apartments by Wynwood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

10/10 Excellent
"Beautiful hotel, amazing food, and even better staff. Everyone went above and beyond to genuinely make us feel welcome, and you could tell they took a lot of pride in the hotel and their roles. A special thank you to Jose Luis, Victor, Felix, and the rest of the restaurant staff. They were excellent and a big part of what made our stay so enjoyable. We will definitely be staying at Central Hotel again when we’re back in Panama next year. Highly recommend!"
Cale 7-night trip
Posted 4 hours ago
Central Hotel Panama Casco Viejo

Find out more about Panama City

You always said you would go on a dream holiday someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannonball into the deep end. Go ahead, unplug and unwind in style. When you book one of our Panama City holiday rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your holiday just got upgraded.

As much as you love your vacation rental, it’s always good to get out and explore to soak up Panama City. Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in Panama City. Seeing all the best attractions is bound to make you fall in love with Panama City. Who knows, you may even be tempted to extend your stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. 

It’s your escape so why share it? You deserve your own slice of paradise. Booking your holiday rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in Panama City short-term rentals, that won’t be hard to do.

Explore a world of travel with Expedia

Frequently asked questions

Can I find holiday rentals in Panama City?

Yes, there are holiday rentals in Panama City close to Panama Canal Railway, or you can select a more secluded option if you're looking for a relaxing stay. Tourists like the array of shops and top-notch restaurants in Panama City. While you're in the area, grab a bite or have a drink at the lively bars and cafes.

What are some of the best holiday rentals that Panama City has to offer?

Downtown Villa with Private Pool & Bar: This highly rated holiday home rental in Panama City offers an outdoor pool, a patio and air conditioning to help you feel perfectly comfortable in your new surroundings. It has 8 bedrooms, as well as a kitchen with a fridge, a stovetop and kitchenware, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a garden. Some other top choices in Panama City are Casa Randa: 6 Ensuite Bedrooms near the Panama Canal and Two Floors Duplex in the middle of Panama City..

How many holiday rentals are there in Panama City?

With 59 Expedia holiday rentals, you're guaranteed to find just the right place for your Panama City stay.

What can I see and do in Panama City?

Cultural attractions include National Theater and Interoceanic Canal Museum, whereas Cinta Costera and Miraflores Locks are a couple of picturesque spots to enjoy the outdoors. Albrook Shopping Mall and Via Espana are other places to visit while you're in town.

What are holiday rentals like in Panama City?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Panama City. Holiday rentals offer extras like WiFi and washers and dryers so you'll feel right at home. If you're concerned about a clean environment, holiday rentals can provide a sense of privacy away from public hotel lifts and lobbies bustling with people while still allowing you a great travel experience. You'll also get more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great choice for family gatherings.