San Francisco Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by Fabiola Tile

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    Save up to NZ$616 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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Our guide on where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about San Francisco
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Casco Viejo

5/5(2 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Find hotels in Casco Viejo

Our pick of the best San Francisco Hotel Deals

Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is NZ$246 per night from 26 Sept to 27 Sept
NZ$246
26 Sept - 27 Sept
includes taxes & fees
8.4/10 Very Good! (947 reviews)
"My favorite things were the Bakery, a restaurant and a Casino on property."

Reviewed on 14 Sept 2025

Sheraton Grand Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
Fully refundableReserve now, pay when you stay
The price is NZ$233 per night from 19 Sept to 20 Sept
NZ$233
19 Sept - 20 Sept
includes taxes & fees
8.2/10 Very Good! (1,077 reviews)
"Very beautiful"

Reviewed on 16 Sept 2025

Megapolis Hotel Panamá
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is NZ$404 per night from 18 Oct to 19 Oct
NZ$404
18 Oct - 19 Oct
includes taxes & fees
8.8/10 Excellent! (1,003 reviews)
"I love the spa and everything else"

Reviewed on 6 Sept 2025

JW Marriott Panama
See all 1,538 properties in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Francisco holiday package cost?
Much less than you might think — from a low , in fact! By bundling hotels, flights and car rentals into a custom-built holiday package, your San Francisco escape is only clicks away.
How do I get a cheap travel package to San Francisco?
Lock in flights that suit your schedule, add a hotel to your booking and watch how much you save with a San Francisco holiday package. It's that easy! From flights and hotels to rental cars and activities, Expedia makes travelling on the cheap easy. And with more than 550 partner airlines and 1 000 000 hotel options around the globe to pick from, you'll never be short of choice.
Where should I stay in San Francisco?
Make sightseeing easy by staying near San Francisco's main attractions. Miraflores Locks and Metropolitan Cathedral of Panama are two which top many visitors' bucket lists.
What are the top hotels in San Francisco?
If this will be your first visit to San Francisco, secure a room at Sublime Apartment City Centre. Ph Boutique Quartier Atlapa or New Cosy Apartment Ocean View. Quartier Del Mar. Both hotels will make you feel at home and are popular options with lots of travellers.
How far in advance should I book my San Francisco holiday?
It can be hard to know when is the ideal time to book your trip to San Francisco. But typically the earlier you book, the lower the prices. Sometimes, you can reserve your flights and hotels up to a year prior to your departure date. If you're eager to escape on a last-minute getaway, no need to fret! There are unbeatable deals announced on Expedia every day.
What does an Expedia San Francisco travel package include?
That mostly depends on you. You can choose from a range of San Francisco packages, such as a hotel, rental car and flight. You can also book a hotel and a flight, or a flight and a rental car. Once you've made your booking, you can add the fun stuff like experiences and tours. Whatever your ideal San Francisco holiday looks like, you're sure to save!
What should I know before booking a San Francisco travel package?
So many places to go, so many things to see and do. With a travel package, you'll be able to afford more of them. Bundle your hotels, flights and rental cars and land big savings.
Can I choose my airline with a San Francisco Expedia holiday package?
Yes, definitely. Expedia has more than 550 airline partners to choose from worldwide. With such a huge range of choice, finding the ideal carrier to whisk you off to San Francisco won't be difficult.
If I'm not able to travel, can I cancel my San Francisco holiday package?
Your situation can change in a flash, so yes, you can. You may be able to amend or cancel your San Francisco holiday package for free if you've booked in the last 24 hours. For older bookings, you can still make changes, but your car rental company, airline or hotel may charge a fee. Need more information? Look up our Customer Service Portal. We'll help make sure your trip goes off without a hitch.

Discover the most popular places to visit in San Francisco

Multicentro Panama

During your trip to Panama City, you can find the perfect gifts to bring home at Multicentro Panama. Stroll along the seaside or visit the casinos in this vibrant area.

Multicentro Panama

Hospital Punta Pacífica

If Hospital Punta Pacífica is what brings you to town, hopefully you'll have a chance to explore more of Panama City.

Hospital Punta Pacífica

Activities

Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

NZ$252
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Boat tour in the Panama Canal to Monkeys and sloths islands

Boat tour in the Panama Canal to Monkeys and sloths islands

NZ$125
per adult
96% of travellers recommend
Boat tour in the Panama Canal to Monkeys and sloths islands
La casa de papel Day tour in San Blas Islands - All inclusive- No hidden fees.

All included - Day tour in San Blas Islands - No extra fees

NZ$185
per adult
All included - Day tour in San Blas Islands - No extra fees
See all activities in Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.