Santa Ana Hotels, Panama City

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Tonight
25 Sept - 26 Sept
Tomorrow
26 Sept - 27 Sept
This weekend
26 Sept - 28 Sept
Next weekend
3 Oct - 5 Oct

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1532 Cheap Hotels in Santa Ana - Specials, Reviews, & Last Minute Deals

Our top choices for Santa Ana hotels

Casco View Apartments
Luxury Apartment | Balcony

Casco View Apartments

3.5 star property
9.4 out of 10, Exceptional, (47)
"Great stay, would recommend."
Casco View Apartments
Hostal La Cigarra
Bar (on property)

Hostal La Cigarra

2.5 star property
7.4 out of 10, Good, (53)
"Helpful staff, secure, close to sights"
Hostal La Cigarra
Hotel República
Balcony

Hotel República

2.0 star property
6.6 out of 10, (176)
"Fantastic customer service"
Hotel República
La Manzana by Wynwood House
Apartment (20)

La Manzana by Wynwood House

3.0 star property
7.0 out of 10, Good, (14)
"Great hotel. Very close to Casco viejo"
The price is NZ$116
includes taxes & fees
28 Sept - 29 Sept
La Manzana by Wynwood House
Casa Quijano 06 By Wynwood House
Apartment | Terrace/patio

Casa Quijano 06 By Wynwood House

4.0 star property
9.0 out of 10, Wonderful, (4)
"The apartment itself was very nice, very spacious, clean, newer furniture. Just know it’s on the third floor and there is no elevator. I didn’t see a sign on the building so it was a bit tricky to figure out which door to go to after being dropped off by the Uber. Email communication from property with building entry code and picture of the property was helpful. There are two balconies but all you really see is the apartment immediately in front of you, and so just know people can see you if you...
The price is NZ$152
includes taxes & fees
26 Sept - 27 Sept
Casa Quijano 06 By Wynwood House
ART CASCO The Hotel
Front of property

ART CASCO The Hotel

2.0 star property
6.6 out of 10, (8)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
ART CASCO The Hotel
Hotel Riazor
Single Room

Hotel Riazor

3.0 star property
3.8 out of 10, (11)
"Rough neighborhood "
Hotel Riazor
Room-sofa Bed Stay Rooftop Pool & Gym, A
Room, Multiple Bedrooms, Accessible, Smoking | Pool

Room-sofa Bed Stay Rooftop Pool & Gym, A

2.0 star property
2.0 out of 10, (1)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
The price is NZ$271
includes taxes & fees
30 Sept - 1 Oct
Room-sofa Bed Stay Rooftop Pool & Gym, A
w Charming 1BR in Santa Ana s Best Area
Apartment

w Charming 1BR in Santa Ana s Best Area

2.0 star property
The price is NZ$156
includes taxes & fees
26 Sept - 27 Sept
w Charming 1BR in Santa Ana s Best Area
Hyatt Regency Panama City
Restaurant

Hyatt Regency Panama City

4.5 star property
10.0 out of 10, Exceptional, (73)
"Great service & clean room throughout stay"
The price is NZ$316
includes taxes & fees
27 Sept - 28 Sept
Hyatt Regency Panama City
Panama House Bed & Breakfast
Terrace/patio

Panama House Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (172)
"Was amazing the host and the people there was super friendly and welcoming. Also has amazing local food spots within walking distance."
Panama House Bed & Breakfast
Gran Evenia Panama
Outdoor pool, pool loungers

Gran Evenia Panama

4.5 star property
9.2 out of 10, Wonderful, (182)
"Excellent hotel and staff."
Gran Evenia Panama
Toscana Inn
Exterior

Toscana Inn

3.5 star property
9.0 out of 10, Wonderful, (721)
"Great hotel"
Toscana Inn
Renaissance Panama City Hotel
40-inch Smart TV with cable channels, TV

Renaissance Panama City Hotel

5.0 star property
9.0 out of 10, Wonderful, (63)
"The Room was very clean, all staff were very kind and professional, the breakfast and dinner are so delicious, nothing comparative with other restaurant around. "
The price is NZ$195
includes taxes & fees
3 Oct - 4 Oct
Renaissance Panama City Hotel
Hotel Milan
Exterior

Hotel Milan

3.0 star property
9.0 out of 10, Wonderful, (397)
"I enjoyed my stay "
The price is NZ$75
includes taxes & fees
26 Sept - 27 Sept
Hotel Milan
Hotel Riu Plaza Panama
Outdoor pool, pool loungers

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4327)
"Really nice hotel With very good breakfast options "
The price is NZ$224
includes taxes & fees
28 Sept - 29 Sept
Hotel Riu Plaza Panama
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Suite, 1 Bedroom, Non Smoking, Golf View (Terrace)

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (608)
"Staff was lovely - especially front desk, door staff, cleaning team and room service. Only critique is that service was very slow in the restaurant both times but otherwise a lovely visit. "
The price is NZ$417
includes taxes & fees
3 Oct - 4 Oct
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Best Western Plus Panama Zen Hotel
Outdoor pool, pool umbrellas, pool loungers

Best Western Plus Panama Zen Hotel

4.0 star property
9.0 out of 10, Wonderful, (941)
"The staff was very nice love to stay every time I go home "
The price is NZ$150
includes taxes & fees
25 Oct - 26 Oct
Best Western Plus Panama Zen Hotel
TRYP by Wyndham Panamá Centro
Exterior

TRYP by Wyndham Panamá Centro

3.5 star property
9.2 out of 10, Wonderful, (1014)
"Place was very clean, lovely staff."
The price is NZ$154
includes taxes & fees
26 Sept - 27 Sept
TRYP by Wyndham Panamá Centro
Novotel Panama City
Front of property

Novotel Panama City

4.0 star property
9.0 out of 10, Wonderful, (1021)
"The Staff were all welcoming location was very convenient I highly recommend "
The price is NZ$189
includes taxes & fees
11 Oct - 12 Oct
Novotel Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Our guide on where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Top Santa Ana Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Everything and everyone was great food and the service from all staff was excellent "
Marvalyn 4-night trip
Posted 4 hours ago
Hotel Riu Plaza Panama

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Cinta Costera and Avenida Balboa while you're in the neighbourhood.

Where is the best hotel for a stay in Santa Ana?

Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.

How many hotels can I expect to find in Santa Ana?

Expedia has 116 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.

What is there to do in this Panama City neighbourhood?

If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighbourhood. Albrook Shopping Mall, Amador Theater and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.