Santa Ana Hotels, Panama City

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Our top choices for Santa Ana hotels

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (85 reviews)
"The staff was absolutely phenomenal! So kind and accommodating even when certain events were out of their control they were still so wonderful!"
United States
Nicole
The price is NZ$230
includes taxes & fees
3 Apr - 4 Apr
Casco View Apartments

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (65 reviews)
"Excelente "
Mexico
David
The price is NZ$48
includes taxes & fees
6 Apr - 7 Apr
Hostal La Cigarra

La Manzana by Wynwood House

La Manzana by Wynwood House
3.0 star property
Santa Ana
7.2 out of 10, Good, (15 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is NZ$198
includes taxes & fees
7 Apr - 8 Apr
La Manzana by Wynwood House

Hotel República

Hotel República
2.0 star property
Santa Ana
6.6 out of 10, (188 reviews)
"It's meant for a short stay, close to Casco Viejo and coast line. Clean bed and bathroom. Needs some maintenance. Beware, there's no hot water if that's a deal breaker for you."
United States
Mario
The price is NZ$49
includes taxes & fees
28 Apr - 29 Apr
Hotel República

ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is NZ$71
includes taxes & fees
1 Apr - 2 Apr
ART CASCO The Hotel

Villa Caprichosa

Villa Caprichosa
3.0 star property
18.3 km from Santa Ana
9.8 out of 10, Exceptional, (58 reviews)
"Would definitely visit again "
United States
John
The price is NZ$379
includes taxes & fees
12 Apr - 13 Apr
Villa Caprichosa

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (91 reviews)
"Great place to stay with plenty of places nearby for food and drinks"
United States
Thomas
The price is NZ$271
includes taxes & fees
8 Apr - 9 Apr
ORHO HOTEL BOUTIQUE PANAMA Airport

Gamboa Rainforest Reserve

Gamboa Rainforest Reserve
3.5 star property
24.7 km from Santa Ana
8.0 out of 10, Very good, (731 reviews)
"Clean room, kind staff, good amenities and beautiful place with a lot of nature."
United States
Kazumi
The price is NZ$291
includes taxes & fees
15 Apr - 16 Apr
Gamboa Rainforest Reserve

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,500 reviews)
"Very clean and comfortable stay, beautiful lobby and restaurant."
United States
EL Heru
The price is NZ$260
includes taxes & fees
1 May - 2 May
Crowne Plaza Panama Airport by IHG

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very good, (1,859 reviews)
"Property was good, would stay there again. "
United States
Juan
The price is NZ$239
includes taxes & fees
8 Apr - 9 Apr
Riande Aeropuerto Hotel & Casino

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este, 10.2 km from Santa Ana
9.2 out of 10, Wonderful, (255 reviews)
"All units are very well equipped with everything that travelers will need. Comfortable and well located, easy access and safe neighborhood. "
United States
Jaime
The price is NZ$310
includes taxes & fees
3 Apr - 4 Apr
Arcadia Condo Suites

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
14.7 km from Santa Ana
9.0 out of 10, Wonderful, (1,009 reviews)
"Nice hotel will visit again"
United States
Deisha
The price is NZ$211
includes taxes & fees
27 Apr - 28 Apr
Courtyard by Marriott Panama Metromall

Panama Canal Inn

Panama Canal Inn
3.0 star property
2.4 km from Santa Ana
8.6 out of 10, Excellent, (19 reviews)
"Excellent hotel, good location, nice stay and great service."
United States
Rocio Hernandez
The price is NZ$104
includes taxes & fees
1 Apr - 2 Apr
Panama Canal Inn

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco, 5.7 km from Santa Ana
8.6 out of 10, Excellent, (1,005 reviews)
"Breakfast was great , clean room and staff was nice "
United States
Pauline
The price is NZ$287
includes taxes & fees
1 May - 2 May
Sheraton Grand Panama

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 12.7 km from Santa Ana
9.6 out of 10, Exceptional, (681 reviews)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is NZ$472
includes taxes & fees
5 Apr - 6 Apr
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador, 2.3 km from Santa Ana
8.6 out of 10, Excellent, (1,009 reviews)
"Breakfast buffet was good."
United States
CHRISTIAN
The price is NZ$145
includes taxes & fees
19 Apr - 20 Apr
Radisson Hotel Panama Canal

The Beach House

The Beach House
3.0 star property
Amador, 4.8 km from Santa Ana
8.4 out of 10, Very good, (426 reviews)
"Everting was clean and good nice place to stay "
United States
Kristine
The price is NZ$136
includes taxes & fees
6 Apr - 7 Apr
The Beach House

Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Campo Alegre, 3.3 km from Santa Ana
9.6 out of 10, Exceptional, (231 reviews)
"Great staff and the food was amazing. "
United States
Nyrisha
The price is NZ$273
includes taxes & fees
7 Apr - 8 Apr
Hyatt Regency Panama City

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este, 9.4 km from Santa Ana
9.0 out of 10, Wonderful, (325 reviews)
"Clean room, helpful staff, good breakfast."
United States
Stephanie
The price is NZ$396
includes taxes & fees
1 May - 2 May
The Westin Panama

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador, 4.8 km from Santa Ana
8.0 out of 10, Very good, (240 reviews)
"It’s always a pleasure to stay at the Marinn Tropical every time I visit Panamá City. "
United States
Lori
The price is NZ$192
includes taxes & fees
8 Apr - 9 Apr
MARINN Tropical Vibes Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
85 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
65 reviews
View
Double Room | View from room
Hotel República
2.0 star property
6.6
188 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View
Café
Hotel Doral
2.5 star property
6.2
29 reviews
View

Our guide on where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or National Theater while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Fiesta Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and National Theater.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Cinta Costera and Avenida Balboa while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Ana?
Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.
How many hotels can I expect to find in Santa Ana?
Expedia has 115 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana, Avenida Central and Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighbourhood. Albrook Shopping Mall, Amador Theater and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.

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