A waterfront with Spanish moss-covered trees, a wooden dock, and a distant shoreline.

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Check prices for these dates

Tonight
3 Oct - 4 Oct
Tomorrow
4 Oct - 5 Oct
Next weekend
9 Oct - 11 Oct
In two weeks
16 Oct - 18 Oct

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Our top choices for Melrose hotels

1. Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
Waldo
United States
Ana Laura
NZ$187
includes taxes & fees
11 Oct - 12 Oct
Best Western Waldo Inn and Suites

2. Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
Starke
United States
Judy
NZ$217
includes taxes & fees
11 Oct - 12 Oct
Holiday Inn Express Starke by IHG

3. Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
Downtown Gainesville
United States
Claire
NZ$196
includes taxes & fees
11 Oct - 12 Oct
Hyatt Place Gainesville Downtown

4. Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
Gainesville
United States
thomas
NZ$171
includes taxes & fees
11 Oct - 12 Oct
Comfort Suites Gainesville near University

5. Sweetwater Branch Inn

Sweetwater Branch Inn
Gainesville
United States
Jose
NZ$227
includes taxes & fees
6 Oct - 7 Oct
Sweetwater Branch Inn

6. Soho Inn Waldo

Soho Inn Waldo
Waldo
United States
Keith
NZ$108
includes taxes & fees
5 Oct - 6 Oct
Soho Inn Waldo

7. Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
Gainesville
United States
Joan
NZ$210
includes taxes & fees
8 Oct - 9 Oct
Drury Inn & Suites Gainesville

8. Hampton Inn & Suites Gainesville Downtown University

Hampton Inn & Suites Gainesville Downtown University
Downtown Gainesville
United States
Graziella
NZ$187
includes taxes & fees
11 Oct - 12 Oct
Hampton Inn & Suites Gainesville Downtown University

9. Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
Gainesville
United States
sherry
NZ$177
includes taxes & fees
12 Oct - 13 Oct
Country Inn & Suites by Radisson, Gainesville, FL

10. The Humming Bird Suite - Affordable Lakefront Fun

The Humming Bird Suite - Affordable Lakefront Fun
Keystone Heights
NZ$219
includes taxes & fees
5 Oct - 6 Oct
The Humming Bird Suite - Affordable Lakefront Fun

11. Best Western Starke

Best Western Starke
Starke
United States
Christopher
NZ$206
includes taxes & fees
5 Oct - 6 Oct
Best Western Starke

12. Holiday Inn Express & Suites Gainesville I-75 by IHG

Holiday Inn Express & Suites Gainesville I-75 by IHG
Gainesville
United States
Meredith
NZ$220
includes taxes & fees
3 Nov - 4 Nov
Holiday Inn Express & Suites Gainesville I-75 by IHG

13. Holiday Inn Gainesville - University Center by IHG

Holiday Inn Gainesville - University Center by IHG
University Heights
United States
Joseph
NZ$210
includes taxes & fees
7 Oct - 8 Oct
Holiday Inn Gainesville - University Center by IHG

14. Red Carpet Inn

Red Carpet Inn
Starke
United States
Mark
NZ$136
includes taxes & fees
5 Oct - 6 Oct
Red Carpet Inn

15. Home2 Suites by Hilton Gainesville Medical Center

Home2 Suites by Hilton Gainesville Medical Center
Gainesville
United States
Karri
NZ$220
includes taxes & fees
11 Oct - 12 Oct
Home2 Suites by Hilton Gainesville Medical Center

16. Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
Gainesville
United States
prakasa Babu
NZ$162
includes taxes & fees
26 Oct - 27 Oct
Sleep Inn & Suites University/Shands

17. Fairfield Inn & Suites by Marriott Gainesville I-75

Fairfield Inn & Suites by Marriott Gainesville I-75
Gainesville
United States
Robert
NZ$238
includes taxes & fees
11 Oct - 12 Oct
Fairfield Inn & Suites by Marriott Gainesville I-75

18. SpringHill Suites by Marriott Gainesville

SpringHill Suites by Marriott Gainesville
Gainesville
United States
Robert
NZ$179
includes taxes & fees
13 Oct - 14 Oct
SpringHill Suites by Marriott Gainesville

19. Aloft by Marriott Gainesville University Area

Aloft by Marriott Gainesville University Area
Gainesville
United States
Elizabeth H
NZ$206
includes taxes & fees
12 Oct - 13 Oct
Aloft by Marriott Gainesville University Area

20. Staybridge Suites Gainesville I-75 by IHG

Staybridge Suites Gainesville I-75 by IHG
Gainesville
United States
Lara
NZ$288
includes taxes & fees
5 Oct - 6 Oct
Staybridge Suites Gainesville I-75 by IHG
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Learn more about Melrose

Nestled along Lake Santa Fe, this charming town offers peaceful kayaking and fishing at Melrose Bay Park. Art lovers can browse local galleries and studios, then enjoy fresh farm-to-table dining at the weekend farmers' market.

See all hotels in Melrose
A waterfront with Spanish moss-covered trees, a wooden dock, and a distant shoreline.
Photo by Matt Mateo

Top Melrose Hotel Reviews

Recent Reviews in Melrose

Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville

10/10 Excellent
"Great location, clean too A, and great breakfast and dinner options."
Adam 4-night trip
Posted 5 hours ago
Drury Inn & Suites Gainesville
Gainesville Lodge

Gainesville Lodge

10/10 Excellent
"Will be booking here again and again whenever needing a place to stay in Gainesville. The rooms are clean, comfortable, and there's not enough love in the world to give to the staff."
Evangeline 2-night trip
Posted 1 day ago
Gainesville Lodge
Days Inn by Wyndham Gainesville Hospital/University Area

Days Inn by Wyndham Gainesville Hospital/University Area

10/10 Excellent
"The room was smoke free and very clean. I wish all properties could that clean and smoke free place. Also the bed,cabinets were made of good and strong materials"
ABDUL-HANAN 1-night trip
Posted 1 day ago
Days Inn by Wyndham Gainesville Hospital/University Area
Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL

10/10 Excellent
"The housekeepers should have checked behind the furniture prior to clearing it for the next occupants. The windows are not noise-quiet; we heard police sirens; motorists doing wheelies, and etc., during the nights. The parking was great. I Unable to eat breakfast due to a medical procedure next morning."
William 1-night trip
Posted 2 days ago
Country Inn & Suites by Radisson, Gainesville, FL
3 Bedroom House on Private Scenic Lake Mable

3 Bedroom House on Private Scenic Lake Mable

10/10 Excellent
"Very cozy, peaceful, laid back. It was just what we needed that weekend since we where dropping our son of at UF."
Heriberto 2-night trip
Posted 1 month ago
3 Bedroom House on Private Scenic Lake Mable

More cheap accommodation in Melrose

Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville

3500 Southwest 42nd St Gainesville FL
NZ$108
7 Oct - 8 Oct
includes taxes & fees
Red Roof Inn PLUS+ Gainesville
HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western

3905 Sw 43Rd St Gainesville FL
NZ$154
11 Oct - 12 Oct
includes taxes & fees
8.6/10 Excellent! (2,150 reviews)
HOM Hotel Gainesville, SureStay Collection by Best Western
Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands

4110 SW 40th Boulevard Gainesville FL
NZ$162
26 Oct - 27 Oct
includes taxes & fees
Sleep Inn & Suites University/Shands
Comfort Inn Gainesville - University Area

Comfort Inn Gainesville - University Area

3440 SW 40th Blvd Gainesville FL
NZ$170
15 Oct - 16 Oct
includes taxes & fees
Comfort Inn Gainesville - University Area
Comfort Suites Gainesville near University

Comfort Suites Gainesville near University

2603 SW 13TH STREET Gainesville FL
NZ$171
11 Oct - 12 Oct
includes taxes & fees
Comfort Suites Gainesville near University
Quality Inn & Suites Palatka Riverfront

Quality Inn & Suites Palatka Riverfront

201 N 1st Street Palatka FL
NZ$187
1 Nov - 2 Nov
includes taxes & fees
Quality Inn & Suites Palatka Riverfront

Frequently asked questions

What is the best area to stay in Melrose?
The best area to stay in Melrose is typically around the shores of Lake Melrose, particularly on the northern and western sides.This area provides direct access to the lake, which is the heart of Melrose's recreational activities. Properties here often feature private docks, offering convenience for those who enjoy boating, fishing, or simply relaxing by the water. The main roads like State Road 21 run nearby, providing easy access to local shops and eateries while still maintaining a peaceful, residential feel.Families often find this area ideal due to the focus on outdoor activities. Children can enjoy swimming, kayaking, or paddleboarding directly from their accommodation, and the open spaces around the lake are great for playing. The proximity to nature trails also offers opportunities for family walks and exploring the local wildlife.Couples looking for a peaceful retreat will appreciate the quiet surroundings and scenic views of the lake. Many accommodations in this area offer private settings, great for romantic evenings watching the sunset over the water or enjoying a quiet morning coffee on a lakeside porch.
When is the best time to go to Melrose?
The best time to go to Melrose, Florida, is during the spring (March to May) and autumn (September to November) months.During these periods, the weather is pleasantly warm with lower humidity, making it ideal for enjoying outdoor activities. Average temperatures range from 20-28°C (68-82°F), great for exploring the natural beauty of the area, like kayaking on Lake Santa Fe or hiking in the nearby state parks. These seasons also avoid the peak summer heat and the higher risk of hurricanes.Couples looking for a peaceful escape will appreciate the quieter atmosphere during these shoulder seasons. You can enjoy strolls through the small town centre, visit local antique shops, or have a relaxed meal at one of the lakeside restaurants without the larger crowds of peak tourist times.Families will find these times suitable for outdoor adventures. The comfortable temperatures mean children can comfortably explore the parks and enjoy water activities without the intensity of summer heat.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, although it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24 to 48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to 'My Trips' and selecting your reservation. To find flexible deals, filter your search by 'Fully refundable property' for hotels in Melrose.
How can I save on a hotel booking in Melrose with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Melrose hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Melrose?
Prices for hotels in Melrose often vary, but you can find a great deal from NZ$90 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by 'Price: low to high' for our cheapest rates.

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