Lake Nona Medical City Hotels, Orlando

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
8 Sept - 9 Sept
Tomorrow
9 Sept - 10 Sept
This weekend
12 Sept - 14 Sept
Next weekend
19 Sept - 21 Sept

Filter by

Guest rating
Guest rating
Star rating

27348 Cheap Hotels in Lake Nona Medical City - Specials, Reviews, & Last Minute Deals

Our top choices for Lake Nona Medical City hotels

Aloft Orlando Lake Nona
Lounge

Aloft Orlando Lake Nona

3.0 star property
9.6 out of 10, Exceptional, (219)
"Great Staff, Great Place. "
The price is NZ$265
includes taxes & fees
28 Sept - 29 Sept
Aloft Orlando Lake Nona
Courtyard Orlando Lake Nona
Outdoor pool

Courtyard Orlando Lake Nona

3.0 star property
9.6 out of 10, Exceptional, (569)
"Love this place I have stayed here about 6 times for buisness "
The price is NZ$299
includes taxes & fees
21 Sept - 22 Sept
Courtyard Orlando Lake Nona
Residence Inn Orlando Lake Nona
Outdoor pool

Residence Inn Orlando Lake Nona

3.0 star property
9.6 out of 10, Exceptional, (321)
"Good hotel "
The price is NZ$353
includes taxes & fees
21 Sept - 22 Sept
Residence Inn Orlando Lake Nona
La Quinta Inn & Suites by Wyndham Orlando UCF
Lobby

La Quinta Inn & Suites by Wyndham Orlando UCF

3.0 star property
8.6 out of 10, Excellent, (2648)
"Great stay! "
The price is NZ$177
includes taxes & fees
11 Sept - 12 Sept
La Quinta Inn & Suites by Wyndham Orlando UCF
The Delaney Hotel
Terrace/patio

The Delaney Hotel

3.5 star property
9.6 out of 10, Exceptional, (1005)
"great restaurant and even better rooms!"
The Delaney Hotel
Wingate by Wyndham - Orlando International Airport
Pillow-top beds, in-room safe, desk, blackout curtains

Wingate by Wyndham - Orlando International Airport

3.0 star property
8.8 out of 10, Excellent, (3595)
"Great stay for the weekend super close to airport and shops. "
The price is NZ$141
includes taxes & fees
10 Sept - 11 Sept
Wingate by Wyndham - Orlando International Airport
Ramada by Wyndham Suites Orlando Airport
Premium bedding, in-room safe, desk, blackout curtains

Ramada by Wyndham Suites Orlando Airport

3.0 star property
8.2 out of 10, Very good, (4814)
"Enjoyed our stay "
The price is NZ$141
includes taxes & fees
9 Sept - 10 Sept
Ramada by Wyndham Suites Orlando Airport
Ramada by Wyndham Hotel & Water Park
Water park

Ramada by Wyndham Hotel & Water Park

3.0 star property
7.2 out of 10, Good, (1468)
"Excellent place for familys"
The price is NZ$125
includes taxes & fees
10 Sept - 11 Sept
Ramada by Wyndham Hotel & Water Park
Country Inn & Suites by Radisson, Orlando Airport, FL
Exterior

Country Inn & Suites by Radisson, Orlando Airport, FL

3.0 star property
7.8 out of 10, Good, (4019)
"Excelente hotel "
The price is NZ$140
includes taxes & fees
29 Sept - 30 Sept
Country Inn & Suites by Radisson, Orlando Airport, FL
Wyndham Garden Orlando Airport
Outdoor pool, pool loungers

Wyndham Garden Orlando Airport

3.0 star property
9.0 out of 10, Wonderful, (3816)
"Great place to stay."
The price is NZ$166
includes taxes & fees
9 Sept - 10 Sept
Wyndham Garden Orlando Airport
SPOT X Hotel Orlando/Intl Dr by The Red Collection
Front of property - evening/night

SPOT X Hotel Orlando/Intl Dr by The Red Collection

3.0 star property
8.6 out of 10, Excellent, (2718)
"Had a nice stay"
The price is NZ$114
includes taxes & fees
28 Sept - 29 Sept
SPOT X Hotel Orlando/Intl Dr by The Red Collection
La Quinta Inn & Suites by Wyndham Orlando Airport North
Dining

La Quinta Inn & Suites by Wyndham Orlando Airport North

3.0 star property
7.8 out of 10, Good, (7303)
"Wonderful stay. "
The price is NZ$128
includes taxes & fees
1 Oct - 2 Oct
La Quinta Inn & Suites by Wyndham Orlando Airport North
DoubleTree by Hilton at the Entrance to Universal Orlando
Outdoor pool

DoubleTree by Hilton at the Entrance to Universal Orlando

4.0 star property
8.4 out of 10, Very good, (6601)
"It was an amazing stay! "
The price is NZ$177
includes taxes & fees
25 Sept - 26 Sept
DoubleTree by Hilton at the Entrance to Universal Orlando
Lake Nona Wave Hotel
Outdoor pool, open 8:00 AM to 10:00 PM, pool loungers

Lake Nona Wave Hotel

4.0 star property
9.6 out of 10, Exceptional, (1006)
"Great weekend getaway and loved the room, extended my stay!"
The price is NZ$411
includes taxes & fees
22 Sept - 23 Sept
Lake Nona Wave Hotel
The Eo Inn - Downtown
Front of property

The Eo Inn - Downtown

3.0 star property
8.0 out of 10, Very good, (1003)
"Great find with a friendly and hospitable staff!"
The price is NZ$170
includes taxes & fees
9 Sept - 10 Sept
The Eo Inn - Downtown
Kompose Boutique Resort at Theme Parks
Suite, 1 King Bed with Sofa bed, Balcony

Kompose Boutique Resort at Theme Parks

3.0 star property
9.4 out of 10, Exceptional, (1232)
"Great stay"
The price is NZ$133
includes taxes & fees
14 Sept - 15 Sept
Kompose Boutique Resort at Theme Parks
Orlando Palms Hotel
Outdoor pool, open 9 AM to 10 PM, pool loungers

Orlando Palms Hotel

2.5 star property
7.6 out of 10, Good, (2044)
"room was clean and staffs were friendly"
The price is NZ$97
includes taxes & fees
14 Sept - 15 Sept
Orlando Palms Hotel
Rosen Inn International
Front of property - evening/night

Rosen Inn International

3.0 star property
8.4 out of 10, Very good, (5801)
"Will stay here again!"
The price is NZ$141
includes taxes & fees
25 Sept - 26 Sept
Rosen Inn International
Hyatt Regency Grand Cypress
3 outdoor pools, open 7 AM to 10:00 PM, pool cabanas (surcharge)

Hyatt Regency Grand Cypress

4.0 star property
9.2 out of 10, Wonderful, (2239)
"Very beautiful resort."
The price is NZ$378
includes taxes & fees
19 Sept - 20 Sept
Hyatt Regency Grand Cypress
Fairfield Inn By Marriott Orlando Airport
Free daily continental breakfast

Fairfield Inn By Marriott Orlando Airport

3.5 star property
9.2 out of 10, Wonderful, (2185)
"Great place breakfast was great!!! "
The price is NZ$137
includes taxes & fees
14 Sept - 15 Sept
Fairfield Inn By Marriott Orlando Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Magic Kingdom® Theme Park featuring rides and interior views as well as a couple
Photo by ©Disney
Open Photo by ©Disney

Bay Lake

1 out of top 10 points of interest in this area

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

Downtown Orlando

One of the most popular neighborhoods in Florida, this bustling area is full of art galleries, shops, bars and restaurants.

Universal Studios Florida® which includes a city, night scenes and signage

Florida Center

2 out of top 10 points of interest in this area

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

Reunion

The top golf courses and fun-filled water parks are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

Top Lake Nona Medical City Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Lake Nona Medical City?

Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.

What's the best accommodation in Lake Nona Medical City?

Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.

How many hotels will I find in Lake Nona Medical City?

Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.

If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.

What is there to do around this Orlando neighbourhood?

Places you might want to visit in the area around Lake Nona Medical City include Eagle Creek Golf Club and Austin-Tindall Regional Park. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.