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Luxury Hotels & Resorts in Lake Nona Medical City from NZ$195

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Check availability on Lake Nona Medical City Luxury Hotels

This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Lake Nona Medical City luxury hotels

An aerial view of a resort with multiple swimming pools, landscaped gardens, and outdoor seating areas.

1. Rosen Shingle Creek

Rosen Shingle Creek
4.5 star property
Orlando
9.6 out of 10, Exceptional, (4,958 reviews)
  • cleanliness
    Opulent Orlando retreat with 4 outdoor pools, 11 restaurants, and a luxurious spa experience.
The price is NZ$208
includes taxes & fees
17 Oct - 18 Oct
Rosen Shingle Creek
A nighttime view of a hotel pool area with a large pool, sun loungers, and a palm tree.

2. Rosen Plaza on International Drive

Rosen Plaza on International Drive
4.0 star property
International Drive District
9.2 out of 10, Wonderful, (1,958 reviews)
  • cleanliness
    Luxurious retreat offers poolside indulgence and multiple dining options near Orange County Convention Centre.
The price is NZ$196
includes taxes & fees
17 Oct - 18 Oct
Rosen Plaza on International Drive
A hotel pool area with lounge chairs, palm trees, and a large building with vertical lines and green lighting.

3. Rosen Centre Hotel

Rosen Centre Hotel
4.0 star property
International Drive District
9.0 out of 10, Wonderful, (4,442 reviews)
  • cleanliness
    Indulge in refined comfort at this Orlando resort offering full-service spa treatments, 7 upscale restaurants, and poolside relaxation.
The price is NZ$215
includes taxes & fees
28 Oct - 29 Oct
Rosen Centre Hotel
A man holding a glass of champagne overlooking a resort with a pool, lounge chairs, and a large building in the background.

4. Hyatt Regency Orlando

Hyatt Regency Orlando
4.5 star property
International Drive District
9.2 out of 10, Wonderful, (2,088 reviews)
  • cleanliness
    Unwind in ultimate comfort at this Orlando luxury hotel offering 2 outdoor pools, a full-service spa, and refined amenities on the strip.
The price is NZ$387
includes taxes & fees
17 Oct - 18 Oct
Hyatt Regency Orlando
A hotel with a large pool, palm trees, and a waterfall feature.

5. Caribe Royale Orlando, WorldHotels Elite

Caribe Royale Orlando, WorldHotels Elite
4.5 star property
Orlando
9.2 out of 10, Wonderful, (5,325 reviews)
  • cleanliness
    Lavish Orlando retreat featuring a full-service spa, 3 pools, and 5 restaurants for discerning travellers.
The price is NZ$456
includes taxes & fees
9 Oct - 10 Oct
Caribe Royale Orlando, WorldHotels Elite
A water park with multiple slides and a pool area surrounded by palm trees and a golf course.

6. The Ritz-Carlton Orlando, Grande Lakes

The Ritz-Carlton Orlando, Grande Lakes
5.0 star property
Orlando
9.2 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Opulent five-star haven boasts a full-service spa, championship golf course, and 7 restaurants in Orlando.
The price is NZ$962
includes taxes & fees
29 Oct - 30 Oct
The Ritz-Carlton Orlando, Grande Lakes
A bar area with a long counter, multiple stools, and a chandelier.

7. Hotel Beauden, Autograph Collection

Hotel Beauden, Autograph Collection
4.5 star property
Downtown Orlando
9.0 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    City centre luxury hotel with spa sanctuary offers poolside relaxation and upscale dining just steps from Orlando's entertainment district.
The price is NZ$442
includes taxes & fees
15 Oct - 16 Oct
Hotel Beauden, Autograph Collection
A hotel with a swimming pool, lounge chairs, and palm trees.

8. Waldorf Astoria Orlando - An Official Walt Disney World® Hotel

Waldorf Astoria Orlando - An Official Walt Disney World® Hotel
5.0 star property
Orlando
9.4 out of 10, Exceptional, (669 reviews)
  • cleanliness
    Exceptional luxury awaits at this 5-star resort featuring a full-service spa, 2 outdoor pools, and 12 restaurants near Walt Disney World®.
The price is NZ$927
includes taxes & fees
29 Oct - 30 Oct
Waldorf Astoria Orlando - An Official Walt Disney World® Hotel
A hotel with multiple floors, outdoor seating areas, and a well-lit courtyard.

9. The Alfond Inn

The Alfond Inn
4.0 star property
Winter Park
9.6 out of 10, Exceptional, (1,001 reviews)
  • cleanliness
    Tuscan-style elegance in Winter Park offers a boutique retreat with spa services, an outdoor pool, and southern fine dining nearby.
The price is NZ$648
includes taxes & fees
12 Oct - 13 Oct
The Alfond Inn
A resort with multiple swimming pools, lounge areas, and a modern building with balconies.

10. Conrad Orlando at Evermore

Conrad Orlando at Evermore
5.0 star property
Orlando
9.6 out of 10, Exceptional, (594 reviews)
  • cleanliness
    Nestled on a white sand beach, this Orlando resort pampers with a full-service spa, golf course, and private cabanas.
The price is NZ$924
includes taxes & fees
11 Oct - 12 Oct
Conrad Orlando at Evermore
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lake Nona Medical City Hotel Reviews

Drury Plaza Hotel Orlando - Disney Springs Area

Drury Plaza Hotel Orlando - Disney Springs Area

10/10 Excellent
"The Drury Hotel was excellent. The room was large and clean. The bed was comfortable. The staff was friendly. The free breakfast is satisfying. They have an afternoon snack that is great along with free beverages. There is also fresh popped popcorn. There is a laundry facility on-site. They have a large pool and a snack bar by the pool. It is a short walk to Disney Springs. Additionally, they have shuttle buses that can take you to Disney Springs a s well as the four theme park. We were blessed with a room that looked toward Epcot so we could see the fireworks show nightly. Great place. We will stay here again."
William 4-night trip
Posted less than an hour ago
Drury Plaza Hotel Orlando - Disney Springs Area

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Lake Nona Medical City?
Use Expedia to help you arrange a flight to Orlando International Airport (MCO) airport or Kissimmee, FL (ISM-Kissimmee Gateway) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a holiday, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel that has a spa, an indoor pool or luxury bedding, Expedia can help you find the best luxury hotel experience that Lake Nona Medical City offers. During your visit, you might want to enjoy the restaurants which Lake Nona Medical City is known for.
What's there to see and do in Lake Nona Medical City?
Experience Lake Nona Medical City with a stop at Orange County Convention Center, Universal Orlando Resort and Universal Studios Florida. If you have spare time during your trip, you might want to make a stop at Disney Springs™ and Epcot®.

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