Lake Nona Medical City Holidays

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Our guide on where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
International Drive showing landscape views

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Find hotels in International Drive District

Our pick of the best Lake Nona Medical City Hotel Deals

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

4 out of 5
8800 Vistana Centre Dr Orlando FL
Fully refundableReserve now, pay when you stay
The price is NZ$246 per night from 24 Mar to 25 Mar
NZ$246
24 Mar - 25 Mar
includes taxes & fees
9.2/10 Wonderful! (4,745 reviews)
Very late check in which delayed my plans.

Reviewed on 2 Mar 2026

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando

4 out of 5
5780 Major Blvd Orlando FL
Fully refundable
The price is NZ$198 per night from 29 Mar to 30 Mar
NZ$198
29 Mar - 30 Mar
includes taxes & fees
8.4/10 Very Good! (6,866 reviews)
A lot of nice perks. They gave me free fresh-baked cookies when I checked in and that made my day. It's nice that there's a car rental place right there so I rented a car last minute to visit other places. It's a convenient walk to the entrance if all you're doing is Universal Studios.

Reviewed on 2 Mar 2026

DoubleTree by Hilton at the Entrance to Universal Orlando
Vacation Village Orlando, Celebration

Vacation Village Orlando, Celebration

3 out of 5
2975 Arabian Nights Blvd Kissimmee FL
Fully refundableReserve now, pay when you stay
The price is NZ$209 per night from 15 Mar to 16 Mar
NZ$209
15 Mar - 16 Mar
includes taxes & fees
8.6/10 Excellent! (3,511 reviews)
The property is large it included various buildings but the man ones advertised in the pictures are the up to date buildings/hotel rooms. The building we stayed at was extremely outdated and the air in the room was not working/cooling it was a dreadful night of sleeping mixed with a strong old odor ...

Reviewed on 2 Mar 2026

Vacation Village Orlando, Celebration
See all 27,168 properties in Lake Nona Medical City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Lake Nona Medical City holiday package cost?
The cheapest Lake Nona Medical City package is , so your dream trip can become a reality — without burning a hole in your pocket. Combine flights, hotels and car rentals to tailor make a package that suits your travel style.
How do I get a cheap travel package to Lake Nona Medical City?
Find flights that fit your busy schedule, add a hotel to your booking and watch the savings rack up with a Lake Nona Medical City holiday package. It's as easy as that! From flights and hotels to tours and rental cars, Expedia makes travelling cheap and easy. And with more than 550 air carriers and 1 000 000 hotel options globally to pick from, you won't be short of choice.
Where should I stay in Lake Nona Medical City?
With loads to explore in Lake Nona Medical City, it'd be convenient for you to stay close to its attractions. Nemours Childrens Hospital, VA Medical Centre at Lake Nona and University of Central Florida College of Medicine are some fascinating ones to add to your to-do list.
What are the top hotels in Lake Nona Medical City?
Make a reservation at Residence Inn Orlando Lake Nona. It's one of the area's most sought-after properties. Another reputable option in Lake Nona Medical City is Courtyard Orlando Lake Nona.
How far in advance should I book my Lake Nona Medical City holiday?
It depends on the airline, but you can generally look up international fares on Expedia up to a year in advance. While it's generally a good idea to book ahead of time, lucky customers occasionally score a cheaper ticket just weeks prior to the date of departure.
What does an Expedia Lake Nona Medical City travel package include?
Expedia has everything you need to organise your Lake Nona Medical City getaway, but what goes into your package is totally up to you. Choose from a combination of hotels, rental cars and flights. In search of some experiences or tours to keep you busy? Once you've made your booking, you can add them too. Whatever your budget or style, there's a deal to match your needs.
What should I know before booking a Lake Nona Medical City travel package?
Locking in all the parts of your escape together is a great way to save. Combine your airfares, rental cars and hotels into one package. But hotels aren't your only option. Expedia has all types of properties, including holiday homes like beachside villas and city apartments. The list goes on!
Can I choose my airline with a Lake Nona Medical City Expedia holiday package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines worldwide. Our holiday packages give you the freedom to take your pick of available flight, hotel or activity options that fit your needs.
If I'm not able to travel, can I cancel my Lake Nona Medical City holiday package?
Don't worry if you're rethinking your Lake Nona Medical City holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur a fee from your airline, hotel or car rental company. We know life can throw the occasional spanner in the works, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.

Discover the most popular places to visit in Lake Nona Medical City

VA Medical Center at Lake Nona

If VA Medical Center at Lake Nona is what brings you to town, hopefully you'll have a chance to explore more of Orlando.

VA Medical Center at Lake Nona

Nemours Children's Hospital

If Nemours Children's Hospital is what brings you to town, hopefully you'll have a chance to explore more of Orlando.

Nemours Children's Hospital

Activities

Universal Orlando Resort

Universal Orlando Resort Theme Park Tickets

NZ$389
per adult
92% of travellers recommend
Universal Orlando Resort Theme Park Tickets
Aquatica Orlando

Aquatica Orlando

NZ$88
per traveller
84% of travellers recommend
Aquatica Orlando
Florida: 90 Minute Everglades Cruise

Florida: 90 Minute Everglades Cruise

NZ$92
per adult
100% of travellers recommend
Florida: 90 Minute Everglades Cruise
See all activities in Orlando
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.