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Ladys Island Holiday Rentals

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Holiday Rentals in Ladys Island

Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive

2.0 star property
Beaufort
10.0 out of 10, Exceptional, (2)
"Great place, very spacious and clean"
United States
James R.
Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive

Amazing Airstream, Beaufort, SC-Enjoy the Journey!

Beaufort
9.6 out of 10, Exceptional, (24)
"Quiet, clean, comfortable, near everything, responsive property manager and inexpensive. I will come back. "
United States
Wayne W.
The price is NZ$303
includes taxes & fees
9 Dec - 10 Dec
Amazing Airstream, Beaufort, SC-Enjoy the Journey!

Historic Beaufort, SC Near Parris Island, 4 Bed/2 Bath, Sleeps 7

Beaufort
9.8 out of 10, Exceptional, (27)
"Place was clean comfy, has everything you need. Will definately stay again."
United States
Alma T.
The price is NZ$451
includes taxes & fees
7 Jan - 8 Jan 2026
Historic Beaufort, SC Near Parris Island, 4 Bed/2 Bath, Sleeps 7

Marriott's Barony Beach Club

3.5 star property
Mid Island
9.6 out of 10, Exceptional, (241)
"The staff was so kind. The property and room was clean. "
United States
Sarah
The price is NZ$371
includes taxes & fees
4 Jan - 5 Jan 2026
Marriott's Barony Beach Club

Marriott's Harbour Club

3.5 star property
Sea Pines
9.2 out of 10, Wonderful, (61)
"The staff was extremely inviting, professional, and kind. Parking was extremely easy we stayed in villa 3939. It was very large, clean, and had a great view. The property was conveniently located within the area and very walkable. It is very dark at night but we felt safe walking back from dinner. I’d definitely recommend this property for a quiet and peaceful getaway."
United States
ANGELEE
The price is NZ$310
includes taxes & fees
3 Jan - 4 Jan 2026
Marriott's Harbour Club

501 Sunsuite - New to VRBO! Resort Access Included!

Fripp Island
9.8 out of 10, Exceptional, (11)
"This was a super getaway. From the friendly gate greeting, the comfortable, attractive room, the quick walk to the beach and everything for a wonderful 2 night stay! We hope to visit again!"
United States
Robbie
The price is NZ$624
includes taxes & fees
9 Dec - 10 Dec
501 Sunsuite - New to VRBO! Resort Access Included!

522 Sunsuite - New to VRBO! Resort Access Included!

Fripp Island
9.6 out of 10, Exceptional, (4)
"Relaxation was much needed and host was very accommodating and made check in easy. The room was clean, and perfect for our stay. The location was perfect. "
United States
Felicia R.
The price is NZ$577
includes taxes & fees
5 Jan - 6 Jan 2026
522 Sunsuite - New to VRBO! Resort Access Included!

Mariners' Nautical Nest on Port Royal's Battery Creek

Beaufort
9.8 out of 10, Exceptional, (24)
"We so loved our stay! Our stay was AMAZING! Great location, great views, and the downtown area is very close and easy to get to. Cannot wait to rebook your place!! "
United States
Glenn G.
The price is NZ$360
includes taxes & fees
9 Dec - 10 Dec
Mariners' Nautical Nest on Port Royal's Battery Creek

The Coral Pelican - 1 Block to Sand and Ocean!

Fripp Island
9.8 out of 10, Exceptional, (19)
"Enjoyed our stay here. Kids and husband loved it and we all had a great time on fripp. Would rent again. "
United States
Neely T.
The price is NZ$1,274
includes taxes & fees
3 Jan - 4 Jan 2026
The Coral Pelican - 1 Block to Sand and Ocean!

Gentleman Pirate (Ocean Views!)

Edisto Beach
10.0 out of 10, Exceptional, (15)
"Great vacation home!"
United States
Samuel J.
The price is NZ$781
includes taxes & fees
9 Dec - 10 Dec
Gentleman Pirate (Ocean Views!)

All Inn on Edisto - Cozy Studio Condo Close to Everything

Edisto Beach
9.8 out of 10, Exceptional, (149)
"The property was nice and comfortable. Perfect for a couples get away. We only stayed one night, but were impressed by the property. "
United States
Stephen F.
The price is NZ$337
includes taxes & fees
9 Dec - 10 Dec
All Inn on Edisto - Cozy Studio Condo Close to Everything

Coastal Elegance. Poolside. Just steps from the beach! Cards available.

Fripp Island
9.4 out of 10, Exceptional, (108)
"The property was great. We were close to all the amenities. "
United States
Dave W.
The price is NZ$548
includes taxes & fees
9 Dec - 10 Dec
Coastal Elegance. Poolside. Just steps from the beach! Cards available.

Players Club Resort

4.0 star property
South End
8.0 out of 10, Very good, (10)
"Clean, safe, and relaxing location. Enjoyed the beach and local restaurants. "
United States
Melvin
Players Club Resort

Marriott's Grande Ocean

3.5 star property
South End
9.4 out of 10, Exceptional, (163)
"Great hotel"
United States
WOOJIN
The price is NZ$493
includes taxes & fees
9 Dec - 10 Dec
Marriott's Grande Ocean

Marriott's Heritage Club

3.5 star property
Sea Pines
9.4 out of 10, Exceptional, (67)
"Another great Marriott, super clean and spacious with the comforts we needed to finish out a long trip (e.g. hot tub, laundry, kitchen). Friendly staff and convenient to the forest reserve."
United States
Landry
The price is NZ$310
includes taxes & fees
7 Jan - 8 Jan 2026
Marriott's Heritage Club

Cozy Edisto Condo-Close to the Beach!

Edisto Beach
9.0 out of 10, Wonderful, (83)
"Nice little place for two people."
United States
Melissa C.
The price is NZ$320
includes taxes & fees
9 Dec - 10 Dec
Cozy Edisto Condo-Close to the Beach!

A Room With a View-1 BR Efficiency Condo Close to Everything.

Edisto Beach
9.8 out of 10, Exceptional, (130)
"Perfect spot "
United States
Jennifer S.
The price is NZ$348
includes taxes & fees
9 Dec - 10 Dec
A Room With a View-1 BR Efficiency Condo Close to Everything.

Modern Carriage House in Old Town Bluffton + Walkable to everything!

Old Town Bluffton
9.8 out of 10, Exceptional, (22)
"Nice location in a sweet town"
United States
Maryellen M.
The price is NZ$570
includes taxes & fees
14 Dec - 15 Dec
Modern Carriage House in Old Town Bluffton + Walkable to everything!

Experience USMC History: 10 min to Parris Island

Port Royal
8.8 out of 10, Excellent, (11)
"Port Royal is charming & this was a great place to stay. Right next to a park, very clean and super comfy!"
United States
Julie S.
The price is NZ$378
includes taxes & fees
10 Dec - 11 Dec
Experience USMC History: 10 min to Parris Island

The Offbeat Oasis by the Marsh- State Park Pass Included🏖

Saint Helena Island
10.0 out of 10, Exceptional, (15)
"Beautiful marsh views. Close to the beach and state park. Peaceful and well taken care of. "
United States
Dorothy T.
The price is NZ$550
includes taxes & fees
18 Dec - 19 Dec
The Offbeat Oasis by the Marsh- State Park Pass Included🏖
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Ladys Island Hotel Reviews

Find out more about Ladys Island

Everything you need to know about Ladys Island holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Ladys Island holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Ladys Island holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Ladys Island holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Ladys Island. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Ladys Island holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Ladys Island holiday rentals we have selected for you start as low as NZ$310 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Ladys Island rentals

At Expedia, we put the best Ladys Island holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Ladys Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Ladys Island holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Ladys Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.